This document discusses establishing evidence for enterovirus infection in chronic diseases like type 1 diabetes mellitus (T1DM). It outlines how enteroviruses have been associated with the development of prediabetic autoimmunity and the onset of clinical diabetes through epidemiological, seroprevalence, and temporal correlation studies. Sensitive reverse transcription polymerase chain reaction (RT-PCR) methods need to be used to detect viruses prior to diabetic symptoms in large prospective studies to firmly establish a causal relationship. The authors have developed a sensitive nested RT-PCR protocol and molecular typing methods to identify enterovirus serotypes that will be valuable in examining relationships between specific viruses and diseases.
The Medical Journal of Basra University 2002
Abstract:
Mesotheliomas are rare tumours. While the benign type is curable by surgery, the malignant forms are difficult to diagnose and treat with a bad prognosis even with modern multimodality treatment. Herein we report four cases of mesothelioma in Iraqi housewives (3 pleural and one pericardial). The diagnosis and treatment of these cases are discussed with review of literature. The primary pericardial mesothelioma has presented as cardiac tamponade. Such presentation was reported only once before in the literature. The three cases of pleural mesotheliomas represented all types i.e., the localized benign, localized malignant and the diffuse malignant. Although exposure to asbestos is reported in 72 -95% of the malignant varieties; none of our patients had such an exposure.
Sontext are an International supplier and manufacturer of Decorative and Acoustic Panels. The finishes include Fabric, Wood/Timber, and painted finishes.
Sontext products include Serenity
Fabric Covered acoustic panels, Murano Acoustic Wood/timber panels, Sonofonic Painted acoustic ceiling panels.
Sontext distributes its products throughout the following regions, United Kingdom, Qatar, UAE, Kuwait, Jordan, Italy and Australia.
The Medical Journal of Basra University 2002
Abstract:
Mesotheliomas are rare tumours. While the benign type is curable by surgery, the malignant forms are difficult to diagnose and treat with a bad prognosis even with modern multimodality treatment. Herein we report four cases of mesothelioma in Iraqi housewives (3 pleural and one pericardial). The diagnosis and treatment of these cases are discussed with review of literature. The primary pericardial mesothelioma has presented as cardiac tamponade. Such presentation was reported only once before in the literature. The three cases of pleural mesotheliomas represented all types i.e., the localized benign, localized malignant and the diffuse malignant. Although exposure to asbestos is reported in 72 -95% of the malignant varieties; none of our patients had such an exposure.
Sontext are an International supplier and manufacturer of Decorative and Acoustic Panels. The finishes include Fabric, Wood/Timber, and painted finishes.
Sontext products include Serenity
Fabric Covered acoustic panels, Murano Acoustic Wood/timber panels, Sonofonic Painted acoustic ceiling panels.
Sontext distributes its products throughout the following regions, United Kingdom, Qatar, UAE, Kuwait, Jordan, Italy and Australia.
Managing Security Threat In SaaS Essential: "How To's"Aspire Systems
Despite SaaS helping enterprises survive the economic downturn, uncertainties around security issues still seem to hamper SaaS adoption.
This webinar moderated by Aspire Systems featured SaaS experts Alexey Lef, Chief Technical Architect of SciQuest and Jothi Rengarajan, Senior Technical Architect of Aspire Systems discussing key topics and questions faced by software providers like-
- What is your Security policy? How secure is my data? Who can access my data in your company?
- How separated is my data from your other customers?
- How does your solution address authorization and encryption need?
- What kind of physical security measures are being followed?
At Work, Home or On-the-Go: How to Make Organizing & De-Cluttering Tools Work...ACCO Brands
During this “how-to” session presented at the NAPO 2012 Conference, Lissa Cupp, director of Digital Strategy & e-Commerce for MeadWestvaco Consumer & Office Products, provides innovative thinking for professional organizers and their businesses as well as fresh ideas to help their on-the-go professional or busy “home CEO” clients improve their productivity or organize their space.
Quality of supply and market regulation: survey within EuropeLeonardo ENERGY
Highlights:
* Appreciation of voltage quality is different from appreciation of reliability.
* Voltage quality consists of many different dimensions.
* Measurement of voltage quality needs special measurement devices.
* Cause of lack of voltage quality is often not as clear as lack of reliability.
* Determination of costs of lack of voltage quality is even more complicated.
Veranstaltung "Confluence & JIRA Community Day 2013" in Frankfurt/M. am 21. November 2013.
Eine Präsentation zum Thema "JIRA goes i18n" von Jan Schulz, Head of Project bei der catWorkX GmbH.
Wer ist Stuttgart? Und was bedeutet das für die Menschen, die hier leben? Der stuttgart|salon ist ein exploratives Format auf der Suche nach Fragen und Themen, die verknüpft neue Ansätze bieten und die Basis für Neues Lernen und Innovation schaffen.
Managing Security Threat In SaaS Essential: "How To's"Aspire Systems
Despite SaaS helping enterprises survive the economic downturn, uncertainties around security issues still seem to hamper SaaS adoption.
This webinar moderated by Aspire Systems featured SaaS experts Alexey Lef, Chief Technical Architect of SciQuest and Jothi Rengarajan, Senior Technical Architect of Aspire Systems discussing key topics and questions faced by software providers like-
- What is your Security policy? How secure is my data? Who can access my data in your company?
- How separated is my data from your other customers?
- How does your solution address authorization and encryption need?
- What kind of physical security measures are being followed?
At Work, Home or On-the-Go: How to Make Organizing & De-Cluttering Tools Work...ACCO Brands
During this “how-to” session presented at the NAPO 2012 Conference, Lissa Cupp, director of Digital Strategy & e-Commerce for MeadWestvaco Consumer & Office Products, provides innovative thinking for professional organizers and their businesses as well as fresh ideas to help their on-the-go professional or busy “home CEO” clients improve their productivity or organize their space.
Quality of supply and market regulation: survey within EuropeLeonardo ENERGY
Highlights:
* Appreciation of voltage quality is different from appreciation of reliability.
* Voltage quality consists of many different dimensions.
* Measurement of voltage quality needs special measurement devices.
* Cause of lack of voltage quality is often not as clear as lack of reliability.
* Determination of costs of lack of voltage quality is even more complicated.
Veranstaltung "Confluence & JIRA Community Day 2013" in Frankfurt/M. am 21. November 2013.
Eine Präsentation zum Thema "JIRA goes i18n" von Jan Schulz, Head of Project bei der catWorkX GmbH.
Wer ist Stuttgart? Und was bedeutet das für die Menschen, die hier leben? Der stuttgart|salon ist ein exploratives Format auf der Suche nach Fragen und Themen, die verknüpft neue Ansätze bieten und die Basis für Neues Lernen und Innovation schaffen.
Whitepaper "Mobile Marketing in der Hotellerie"Thomas Hendele
"Das mobile Internet startet durch - wie kann die Hotellerie davon profitieren"
Ein Whitepaper von some communication (Autoren: Wolfgang Schlösser, Thomas Hendele)
Walking through time – einen Spaziergang durch die Geschichte präsentiert Helge David in seinem Vortrag und zeigt, wie Museumsprofile und Ausstellungen in digital erweiterter Form konzipiert werden können. Er stellt ein gemeinsam mit dem Deutschen Museum Bonn konzipiertes Projekt vor, das eine Ausstellung zu Heinrich Hertz – dem berühmten Physiker und Entdecker der elektromagnetischen Wellen – mit dem Stadtraum von Bonn real und digital verbindet und den inhaltlichen und räumlichen Kontext des Museums mit einem Blog, einer digitalen Culturecaching-Stadtralley und digitaler Co-Kuratierung erweitert.
Mobile Anwendungen heben die Trennung vom Ort „Museum“ und dem Stadtraum auf. Per Geo-Tagging und QR-Code lassen sich digitale Inhalte mit dem begehbaren Raum verbinden. Sie erweitern das Angebot des Museums nach Außen und führen zugleich neue Besuchergruppen ins Museum.
Die Ausstellung zu Heinrich Hertz wird vom Deutschen Museum Bonn kuratiert und umgesetzt. Das Blog, die digitale Stadtralley und die digitale Co-Kuratierung werden von Helge David geplant und realisiert.
Museen im Medienwandel: Der digitale KuratorHelge_David
Mobile Anwendungen heben die Trennung vom Ort „Museum“ und dem Stadtraum, der Kulturlandschaft auf. Per Geo-Tagging und QR-Code lassen sich digitale Inhalte mit dem begehbaren Raum verbinden. Sie erweitern das Angebot des Museums in urbane Räume oder in die Landschaft und führen zugleich neue Besuchergruppen ins Museum. Im Museum entstehen neue Aufgabenbereiche und Herausforderungen für den Kurator.
Die folgenden Kommentare wurden von britischen Frauen gemacht, in einem Formular der Child Support Agency (Kindergeldstelle?) in Bezug auf den Vater ihres Kindes. Alle Aussagen sind echt!
Prozessleitsystem in der QuarzsandaufbereitungThomas Schulz
In Hohenbocka entstand Ende letzten Jahres ein Quarzsandaufbereitungswerk mit einem hochmodernen Prozeßleitstand ausgerüstet. Dank des hohen Automatisierungsgrads überwacht und bedient nur ein Anlagenfahrer das ganze Werk.
Avales científicos de Lirón. Programa detallado de I+D, Participación en Congresos Nacionales e Internacionales, Publicación de artículos en revistas de prestigio internacional, Aval de Sociedades Médicas.
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
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