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NURS 6501: Advanced Pathophysiology
Week 1: Cellular Processes and the Genetic EnvironmentOne of the more common biology
analogies refers to cells as the “building blocks” of life. This rightfully places an emphasis on
understanding cells, cellular behavior, and the impact of the environment in which they
function.Such an understanding helps explain how healthy cell activity contributes to good
health. Just as importantly, it helps explain how breakdowns in cellular behavior and
alterations to cells lead to health issues.This week, you examine cellular processes that are
subject to alterations that can lead to disease. You evaluate the genetic environments within
which these processes exist as well as the impact these environments have on
disease.Learning ObjectivesStudents will:Evaluate cellular processes and alterations within
cellular processesEvaluate the impact of the genetic environment on diseaseLearning
ResourcesRequired Readings (click to expand/reduce)Required Media (click to
expand/reduce)Discussion: Alterations in Cellular ProcessesPhoto Credit: Getty ImagesAt
its core, pathology is the study of disease. Diseases occur for many reasons. But some, such
as cystic fibrosis and Parkinson’s Disease, occur because of alterations that prevent cells
from functioning normally.Understanding of signals and symptoms of alterations in cellular
processes is a critical step in diagnosis and treatment of many diseases. For the Advanced
Practice Registered Nurse (APRN), this understanding can also help educate patients and
guide them through their treatment plans.For this Discussion, you examine a case study and
explain the disease that is suggested. You examine the symptoms reported and explain the
cells that are involved and potential alterations and impacts.To prepare:By Day 1 of this
week, you will be assigned to a specific scenario for this Discussion. Please see the “Course
Announcements” section of the classroom for your assignment from your Instructor.By Day
3 of Week 1Post an explanation of the disease highlighted in the scenario you were
provided. Include the following in your explanation:The role genetics plays in the
disease.Why the patient is presenting with the specific symptoms described.The physiologic
response to the stimulus presented in the scenario and why you think this response
occurred.The cells that are involved in this process.How another characteristic (e.g., gender,
genetics) would change your response.Read a selection of your colleagues’ responses.By
Day 6 of Week 1Respond to at least two of your colleagues on 2 different days and
respectfully agree or disagree with your colleague’s assessment and explain your reasoning.
In your explanation, include why their explanations make physiological sense or why they
do notNote: For this Discussion, you are required to complete your initial post before you
will be able to view and respond to your colleagues’ postings. Begin by clicking on the "Post
to Discussion Question" link and then select "Create Thread" to complete your initial post.
Remember, once you click on Submit, you cannot delete or edit your own posts, and you
cannot post anonymously. Please check your post carefully before clicking
on Submit!Submission and Grading InformationGrading CriteriaTo access your rubric:Week
1 Discussion RubricPost by Day 3 of Week 1 and Respond by Day 6 of Week 1To Participate
in this Discussion:Week 1 DiscussionAssignmentPracticum Manual AcknowledgmentThe
Practicum Manual describes the structure and timing of the classroom-based and practicum
experiences and the policies students must follow to be successful in the nurse practitioner
(NP) specialties.Field Experience: MSN Nurse Practitioner Practicum ManualClick here and
follow the instructions to confirm you have downloaded and read the entire MSN Nurse
Practitioner Practicum Manual and will abide by the requirements described in order to
successfully complete this program.What's Coming Up in Week 2?Photo Credit:
[BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesNext week, you will examine
alterations in the immune system and the resultant disease processes. You will also
consider patient characteristics, including racial and ethnic variables, that may impact
altered physiology.Practicum - Upcoming DeadlineIn the Nurse Practitioner programs of
study (FNP, AGACNP, AGPCNP, and PMHNP) you are required to take several practicum
courses. If you plan on taking a practicum course within the next two terms, you will need
to submit your application via Meditrek .For information on the practicum application
process and deadlines, please visit the Field Experience: College of Nursing: Application
Process – Graduate web page.Please take the time to review the Appropriate Preceptors and
Field Sites for your courses.Please take the time to review the practicum manuals, FAQs,
Webinars and any required forms on the Field Experience: College of Nursing: Student
Resources and Manuals web page.Field Experience: College of Nursing Quick AnswersField
Experience: MSN Nurse Practitioner Practicum ManualStudent Practicum Resources: NP
Student OrientationNext WeekTo go to the next week:Week 2 Week 2: Altered
PhysiologyWith a place squarely in the spotlight for patients diagnosed with all manner of
disease, APRNs must demonstrate not only support and compassion, but expertise to guide
patients’ understanding of diagnoses and treatment plans.This expertise goes beyond an
understanding of disease and sciences, such as cellular pathophysiology. APRNs must
become experts in their patients, understanding their medical backgrounds, pertinent
characteristics, and other variables that can be factors in their diagnoses and
treatments.This week, you examine alterations in the immune system and the resultant
disease processes. You consider patient characteristics, including racial and ethnic
variables, and the impact they have on altered physiology.Learning ObjectivesStudents
will:Evaluate cellular processes and alterations within cellular processesAnalyze alterations
in the immune system that result in disease processesIdentify racial/ethnic variables that
may impact physiological functioningEvaluate the impact of patient characteristics on
disorders and altered physiologyLearning ResourcesRequired Readings (click to
expand/reduce)Required Media (click to expand/reduce)Module 1 Assignment: Case Study
AnalysisAn understanding of cells and cell behavior is a critically important component of
disease diagnosis and treatment. But some diseases can be complex in nature, with a variety
of factors and circumstances impacting their emergence and severity.Effective disease
analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the
environments in which cell processes operate, the impact of patient characteristics, and
racial and ethnic variables all can have an important impact.Photo Credit: Getty
Images/Hero ImagesAn understanding of the signals and symptoms of alterations in
cellular processes is a critical step in the diagnosis and treatment of many diseases. For
APRNs, this understanding can also help educate patients and guide them through their
treatment plans.In this Assignment, you examine a case study and analyze the symptoms
presented. You identify cell, gene, and/or process elements that may be factors in the
diagnosis, and you explain the implications to patient health.To prepare:By Day 1 of this
week, you will be assigned to a specific case study for this Case Study Assignment. Please
see the “Course Announcements” section of the classroom for your assignment from your
Instructor.The Assignment (1- to 2-page case study analysis)Develop a 1- to 2-page case
study analysis in which you:Explain why you think the patient presented the symptoms
described.Identify the genes that may be associated with the development of the
disease.Explain the process of immunosuppression and the effect it has on body systems.By
Day 7 of Week 2Submit your Case Study Analysis Assignment by Day 7 of Week
2.Reminder: The College of Nursing requires that all papers submitted include a title page,
introduction, summary, and references. The sample paper provided at the Walden Writing
Center provides an example of those required elements (available
at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted
must use this formatting.Submission and Grading InformationTo submit your completed
Assignment for review and grading, do the following:Please save your Assignment using the
naming convention “M1Assgn+last name+first initial.(extension)” as the name.Click
the Module 1 Assignment Rubric to review the Grading Criteria for the Assignment.Click
the Module 1 Assignment link. You will also be able to “View Rubric” for grading criteria
from this area.Next, from the Attach File area, click on the Browse My Computer button.
Find the document you saved as “M1Assgn+last name+first initial.(extension)” and
click Open.If applicable: From the Plagiarism Tools area, click the checkbox for I agree to
submit my paper(s) to the Global Reference Database.Click on the Submit button to
complete your submission.Grading CriteriaTo access your rubric:Module 1 Assignment
RubricCheck Your Assignment Draft for AuthenticityTo check your Assignment draft for
authenticity:Submit your Module 1 Assignment draft and review the originality
report.Submit Your Assignment by Day 7 of Week 2To participate in this
Assignment:Module 1 AssignmentWhat's Coming Up in Module 2?Photo Credit:
[BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 2, you will analyze
processes related to cardiovascular and respiratory disorders. To do this, you will analyze
alterations in the cardiovascular and respiratory systems and the resultant disease
processes. You will also consider patient characteristics, including racial and ethnic
variables, which may impact physiological functioning and altered physiology.Week 3
Knowledge Check: Cardiovascular and Respiratory DisordersIn the Week 3 Knowledge
Check, you will demonstrate your understanding of the topics covered during Module 2.
This Knowledge Check will be composed of a series of questions related to specific
scenarios provided. It is highly recommended that you review the Learning Resources in
their entirety prior to taking the Knowledge Check, since the resources cover the topics
addressed. Plan your time accordingly.Next ModuleTo go to the next Module:Module 2Week
3: Concepts of Cardiovascular and Respiratory DisordersThe circulatory system and the
respiratory system are powerful partners in health. While they work closely together in
good health, a disease or disorder that manifests in one can have a significant impact on
both, hampering the pair’s ability to collaborate.Cardiovascular and respiratory disease and
disorders are among the most common reasons for hospital visits, and among the leading
causes of fatality. Heart disease and pneumonias are among the most familiar, but a wide
variety of issues can impact physiological functioning of one or both systems.This week, you
examine fundamental concepts of cardiovascular and respiratory disorders. You explore
common diseases and disorders that impact these systems, and you apply the key terms and
concepts that help communicate the pathophysiological nature of these issues to
patients.Learning ObjectivesStudents will:Analyze concepts and principles of
pathophysiology across the lifespanLearning ResourcesRequired Readings (click to
expand/reduce)Required Media (click to expand/reduce)Knowledge Check: Cardiovascular
and Respiratory DisordersIn this exercise, you will complete a 5-essay type question
Knowledge Check to gauge your understanding of this module’s content.Possible topics
covered in this Knowledge Check include:myocardial
infarctionendocarditismyocarditisvalvular disorderslipid panelscoagulationclotting
cascadedeep vein thrombosishypertensionheart failureCOPDasthmapneumoniasPhoto
Credit: Getty Images/Science Photo Library RFComplete the Knowledge Check by Day 7 of
Week 3To complete this Knowledge Check:Module 2 Knowledge CheckWhat’s Coming Up in
Week 4?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesNext
week, you will examine the alterations in the cardiovascular and respiratory systems and
the resultant disease processes through case study analysis. You will also consider patient
characteristics, including racial and ethnic variables, which may impact altered
physiology.Next WeekTo go to the next week:Week 4 Week 4: Alterations in the
Cardiovascular and Respiratory SystemsCardiovascular and respiratory disorders can
quickly become dangerous healthcare matters, and they routinely land among the leading
causes of hospital admissions. Disorders in these areas are complicated by the fact that
these two systems work so closely as contributors to overall health. APRNs working to form
a similarly close partnership with patients must demonstrate not only support and
compassion, but expertise to guide the understanding of diagnoses and treatment plans.
This includes an understanding of patient medical backgrounds, relevant characteristics,
and other variables that can be factors in their diagnoses and treatments.This week, you
examine alterations in the cardiovascular and respiratory systems and the resultant disease
processes. You also consider patient characteristics, including racial and ethnic variables,
and the impact they have on altered physiology.Learning ObjectivesStudents will:Analyze
processes related to cardiovascular and respiratory disordersAnalyze alterations in the
cardiovascular and respiratory systems and the resultant disease processesAnalyze
racial/ethnic variables that may impact physiological functioningEvaluate the impact of
patient characteristics on disorders and altered physiologyLearning ResourcesRequired
Readings (click to expand/reduce)Required Media (click to expand/reduce)Module 2
Assignment: Case Study AnalysisAn understanding of the cardiovascular and respiratory
systems is a critically important component of disease diagnosis and treatment. This
importance is magnified by the fact that these two systems work so closely together. A
variety of factors and circumstances that impact the emergence and severity of issues in one
system can have a role in the performance of the other.Effective disease analysis often
requires an understanding that goes beyond these systems and their capacity to work
together. The impact of patient characteristics, as well as racial and ethnic variables, can
also have an important impact.Photo Credit: yodiyim / Adobe StockAn understanding of the
symptoms of alterations in cardiovascular and respiratory systems is a critical step in
diagnosis and treatment of many diseases. For APRNs this understanding can also help
educate patients and guide them through their treatment plans.In this Assignment, you
examine a case study and analyze the symptoms presented. You identify the elements that
may be factors in the diagnosis, and you explain the implications to patient health.To
prepare:By Day 1 of this week, you will be assigned to a specific case study scenario for this
Case Study Assignment. Please see the “Course Announcements” section of the classroom
for your assignment from your Instructor.Assignment (1- to 2-page case study analysis)In
your Case Study Analysis related to the scenario provided, explain the followingThe
cardiovascular and cardiopulmonary pathophysiologic processes that result in the patient
presenting these symptoms.Any racial/ethnic variables that may impact physiological
functioning.How these processes interact to affect the patient.By Day 7 of Week
4Submit your Case Study Analysis Assignment by Day 7 of Week 4Reminder: The College of
Nursing requires that all papers submitted include a title page, introduction, summary, and
references. The sample paper provided at the Walden Writing Center provides an example
of those required elements (available
at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted
must use this formatting.Submission and Grading InformationTo submit your completed
Assignment for review and grading, do the following:Please save your Assignment using the
naming convention “M2Assgn+last name+first initial.(extension)” as the name.Click
the Module 2 Assignment Rubric to review the Grading Criteria for the Assignment.Click
the Module 2 Assignment link. You will also be able to “View Rubric” for grading criteria
from this area.Next, from the Attach File area, click on the Browse My Computer button.
Find the document you saved as “M2Assgn+last name+first initial.(extension)” and
click Open.If applicable: From the Plagiarism Tools area, click the checkbox for I agree to
submit my paper(s) to the Global Reference Database.Click on the Submit button to
complete your submission.Grading CriteriaTo access your rubric:Module 2 Assignment
RubricCheck Your Assignment Draft for AuthenticityTo check your Assignment draft for
authenticity:Submit your Module 2 Assignment draft and review the originality
report.Submit Your Assignment by Day 7 of Week 4To participate in this
Assignment:Module 2 AssignmentWhat's Coming Up in Module 3?Photo Credit:
[BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 3, you will analyze
processes related to gastrointestinal and hepatobiliary disorders through case study
analysis. To do this, you will analyze alterations in the relevant systems and the resultant
disease processes. You will also consider patient characteristics, including racial and ethnic
variables, which may impact physiological functioning and altered physiology.Week 5
Knowledge Check: Gastrointestinal and Hepatobiliary DisordersIn Week 5 Knowledge
Check, you will demonstrate your understanding of the topics covered during Module 3.
This Knowledge Check will be composed of a series of questions related to specific
scenarios provided. It is highly recommended that you review the Learning Resources in
their entirety prior to taking the Knowledge Check since the resources cover the topics
addressed. Plan your time accordingly.Next ModuleTo go to the next Module:Module 3Week
5: Concepts of Gastrointestinal and Hepatobiliary DisordersPatients of gastrointestinal and
hepatobiliary disorders often face life-altering changes, including changes to diet, new
treatment regimens, and more. For some disorders, treatments can include
surgery.Gastrointestinal conditions, such as ulcers, diverticulitis, and pancreatitis, often
cause varying levels of pain and discomfort. Hepatobiliary conditions can also bring
significant changes to patient routines and well-being.This week, you examine fundamental
concepts of gastrointestinal and hepatobiliary disorders. You explore common disorders in
these categories, and you apply the key terms and concepts that help communicate
the pathophysiological nature of these issues to patients.Learning ObjectivesStudents
will:Analyze concepts and principles of pathophysiology across the life spanLearning
ResourcesRequired Readings (click to expand/reduce)Required Media (click to
expand/reduce)Knowledge Check: Gastrointestinal and Hepatobiliary DisordersIn this
exercise, you will complete a 5-essay type question Knowledge Check to gauge your
understanding of this module’s content.Possible topics covered in this Knowledge Check
include:UlcersHepatitis markersAfter HP shotsGastroesophageal Reflux
DiseasePancreatitisLiver failure—acute and chronicGall bladder diseaseInflammatory
bowel diseaseDiverticulitisJaundiceBilirubinGastrointestinal bleed – upper and
lowerHepatic encephalopathyIntra-abdominal infections (e.g., appendicitis)Renal blood
flowGlomerular filtration rateKidney stonesInfections – urinary tract infections,
pyelonephritisAcute kidney injuryRenal failure – acute and chronicPhoto Credit: Getty
ImagesComplete the Knowledge Check By Day 7 of Week 5To complete this Knowledge
Check:Module 3 Knowledge CheckWhat's Coming Up in Module 4?Photo Credit:
[BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 4, you will analyze
processes related to endocrine disorders. To do this, you will analyze alterations in the
relevant systems and the resultant disease processes. You will also consider patient
characteristics, including racial and ethnic variables, that may impact physiological
functioning and altered physiology.Week 6 Knowledge Check: Endocrine DisordersIn the
Week 6 Knowledge Check, you will demonstrate your understanding of the topics covered
during Module 4. This Knowledge Check will be composed of a series of questions related to
specific scenarios provided. It is highly recommended that you review the Learning
Resources in their entirety prior to taking the Knowledge Check, since the resources cover
the topics addressed. Plan your time accordingly.Also, during this week you will take your
Midterm Exam. Please make sure to finalize and complete your Knowledge Check prior to
completing your exam.Next ModuleTo go to the next Module:Module 4Week 6: Concepts of
Endocrine DisordersEndocrine disorders are complex matters, and there is not always a
one-size-fits-all treatment. Particularly in matters requiring the adjustment of hormone
levels, treatment may require a custom approach tailored to individual patients. An
understanding of these complications is essential to supporting these individual treatment
plans.This week, you examine alterations in the endocrine system and the resultant disease
processes. You also consider patient characteristics, including racial and ethnic variables,
and the impact they have on altered physiology.Learning ObjectivesStudents will:Analyze
concepts and principles of pathophysiology across the lifespanLearning ResourcesRequired
Readings (click to expand/reduce)Required Media (click to expand/reduce)Optional
Resources (click to expand/reduce)Knowledge Check: Endocrine DisordersIn this exercise,
you will complete a 5-essay type question Knowledge Check to gauge your understanding of
this module’s content.Possible topics covered in this Knowledge Check
include:DiabetesHyper- and hypothyroidismAdrenal disordersParathyroidism (hyper and
hypo)Checks & balances / negative feedbackSyndrome of Inappropriate Antidiuretic
HormonePheochromocytosisDiabetes insipidusDiabetic ketoacidosisPhoto Credit: Getty
Images/Science Photo Library RF(Note: It is strongly recommended that you take the
Knowledge Check at least 48 hours before taking the Midterm Exam.)Complete the
Knowledge Check By Day 5 of Week 6To complete this Knowledge Check:Module 4
Knowledge CheckMidterm ExamThis 101-question exam is a test of your knowledge in
preparation for your certification exam. No outside resources, including books, notes,
websites, or any other type of resource, are to be used to complete this exam. You are
expected to comply with Walden University’s Code of Conduct.This exam will be on topics
covered in Weeks 1, 2, 3, 4, 5, and 6. Prior to starting the exam, you should review all of your
materials. This exam is timed with a limit of 2 hours for completion. When time is up, your
exam will automatically submit.(Note: It is strongly recommended that you take the
Knowledge Check at least 48 hours before taking the Midterm exam.)Photo Credit: Getty
ImagesTo prepare:To help you review for your midterm exam, access the Midterm Exam
Review document found in this week's Learning Resources as well as any Knowledge Check
feedback you might have received. (Note: You will also need to review all of your materials
from each of these weeks to also help you better prepare for your midterm.)By Day 7 of
Week 6Submit your Midterm Exam.To complete your exam:Midterm ExamWhat’s Coming
Up in Module 5?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn
Module 5, you will analyze processes related to neurological and musculoskeletal disorders
through case study analysis. To do this, you will analyze alterations in the relevant systems
and the resultant disease processes. You will also consider patient characteristics, including
racial and ethnic variables, which may impact physiological functioning and altered
physiology.Week 7 Knowledge Check: Neurological and Musculoskeletal DisordersIn the
Week 7 Knowledge Check, you will demonstrate your understanding of the topics covered
during Module 5. This Knowledge Check will be composed of a series of questions related to
specific scenarios provided. It is highly recommended that you review the Learning
Resources in their entirety prior to taking the Knowledge Check, since the resources cover
the topics addressed. Plan your time accordingly.Next ModuleTo go to the next
Module:Module 5Week 7: Concepts of Neurological and Musculoskeletal Disorders – Part
1Anatomists often use the analogy of a house to explain the human body, with skeletal
systems, respiratory systems, and circulatory systems represented as a home’s framing
structure, ventilation, and piping, respectively. Such analogies further emphasize the point
that relationships between systems can result in complications when issues arise in one
system.With hundreds of diseases that can impact the brain, spine, and nerves, neurological
disorders represent a complicated array of issues that present significant health concerns.
Disorders such as strokes and Parkinson’s disease not only affect the nervous system,
however; they can have secondary impacts in other areas, especially the musculoskeletal
system.This week, you examine fundamental concepts of neurological disorders. You
explore common disorders that impact these systems and you apply the key terms and
concepts that help communicate the pathophysiological nature of these issues to
patients.Learning ObjectivesStudents will:Analyze concepts and principles of
pathophysiology across the lifespanLearning ResourcesRequired Readings (click to
expand/reduce)Required Media (click to expand/reduce)Knowledge Check: Neurological
and Musculoskeletal DisordersIn this exercise, you will complete a 5-essay type question
Knowledge Check to gauge your understanding of this module’s content.Possible topics
covered in this Knowledge Check include:StrokeMultiple sclerosisTransient Ischemic
AttackMyasthenia gravisHeadacheSeizure disordersHead injurySpinal cord
injuryInflammatory diseases of the musculoskeletal
systemOsteoporosisOsteopeniaBursitisTendinitisGoutLyme
DiseaseSpondylosisFracturesParkinson’sAlzheimer’sThree basic bone-
formations:OsteoblastsOsteocytesOsteoclastsPhoto Credit: Getty Images/Science Photo
LibraComplete the Knowledge Check By Day 7 of Week 7To complete this Knowledge
Check:Module 5 Knowledge CheckNext WeekTo go to the next week:Week 8Week 8:
Concepts of Neurological and Musculoskeletal Disorders – Part 2As homeowners know all
too well, there is a continuous need for maintenance and repair. Some efforts are
precautionary in nature, while others are the result of issues that surface over
time.Similarly, musculoskeletal disorders can develop over time. For some disorders, such
as osteoporosis, precautionary treatments are a potential option. But much like issues that
surface in a home over time, many musculoskeletal issues can be very serious concerns, and
they can have a significant impact on patients’ lives.This week, you continue to examine
fundamental concepts of neurological and musculoskeletal disorders. You explore common
disorders that impact these systems and you apply the key terms and concepts that help
communicate the pathophysiological nature of these issues to patients.Learning
ObjectivesStudents will:Analyze processes related to neurological and musculoskeletal
disordersIdentify racial/ethnic variables that may impact physiological functioningEvaluate
the impact of patient characteristics on disorders and altered physiologyLearning
ResourcesNote: The below resources were first presented in Week 7. If you have previously
reviewed them, you are encouraged to read or view them again here. Required
Readings (click to expand/reduce)Required Media (click to expand/reduce)Module 5
Assignment: Case Study AnalysisAn understanding of the neurological and musculoskeletal
systems is a critically important component of disease and disorder diagnosis and
treatment. This importance is magnified by the impact that that these two systems can have
on each other. A variety of factors and circumstances affecting the emergence and severity
of issues in one system can also have a role in the performance of the other.Effective
analysis often requires an understanding that goes beyond these systems and their mutual
impact. For example, patient characteristics such as, racial and ethnic variables can play a
role.Photo Credit: jijomathai - stock.adobe.comAn understanding of the symptoms of
alterations in neurological and musculoskeletal systems is a critical step in diagnosis and
treatment. For APRNs this understanding can also help educate patients and guide them
through their treatment plans.In this Assignment, you examine a case study and analyze the
symptoms presented. You identify the elements that may be factors in the diagnosis, and
you explain the implications to patient health.To prepare:By Day 1 of this week, you will be
assigned to a specific case study scenario for this Case Study Assignment. Please see the
“Course Announcements” section of the classroom for your assignment from your
Instructor.Assignment (1- to 2-page case study analysis)In your Case Study Analysis related
to the scenario provided, explain the following:Both the neurological and musculoskeletal
pathophysiologic processes that would account for the patient presenting these
symptoms.Any racial/ethnic variables that may impact physiological functioning.How these
processes interact to affect the patient.Day 7 of Week 8Submit your Case Study Analysis
Assignment by Day 7 of Week 8.Reminder: The College of Nursing requires that all papers
submitted include a title page, introduction, summary, and references. The sample paper
provided at the Walden Writing Center provides an example of those required elements
(available at https://academicguides.waldenu.edu/writingcenter/templates). All papers
submitted must use this formatting.Submission and Grading InformationTo submit your
completed Assignment for review and grading, do the following:Please save your
Assignment using the naming convention “M5Assgn+last name+first initial.(extension)” as
the name.Click the Module 5 Assignment Rubric to review the Grading Criteria for the
Assignment.Click the Module 5 Assignment link. You will also be able to “View Rubric” for
grading criteria from this area.Next, from the Attach File area, click on the Browse My
Computer button. Find the document you saved as “M5Assgn+last name+first
initial.(extension)” and click Open.If applicable: From the Plagiarism Tools area, click the
checkbox for I agree to submit my paper(s) to the Global Reference Database.Click on
the Submit button to complete your submission.Grading CriteriaTo access your
rubric:Module 5 Assignment RubricCheck Your Assignment Draft for AuthenticityTo check
your Assignment draft for authenticity:Submit your Module 5 Assignment draft and review
the originality report.Submit Your Assignment by Day 7 of Week 8To participate in this
Assignment:Module 5 AssignmentWhat's Coming Up in Module 6?Photo Credit:
[BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 6, you will identify
processes related to psychological disorders. You will also examine the neurobiology of
various psychological issues and consider variables that may impact physiological
functioning and altered physiology.

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  • 1. NURS 6501: Advanced Pathophysiology Week 1: Cellular Processes and the Genetic EnvironmentOne of the more common biology analogies refers to cells as the “building blocks” of life. This rightfully places an emphasis on understanding cells, cellular behavior, and the impact of the environment in which they function.Such an understanding helps explain how healthy cell activity contributes to good health. Just as importantly, it helps explain how breakdowns in cellular behavior and alterations to cells lead to health issues.This week, you examine cellular processes that are subject to alterations that can lead to disease. You evaluate the genetic environments within which these processes exist as well as the impact these environments have on disease.Learning ObjectivesStudents will:Evaluate cellular processes and alterations within cellular processesEvaluate the impact of the genetic environment on diseaseLearning ResourcesRequired Readings (click to expand/reduce)Required Media (click to expand/reduce)Discussion: Alterations in Cellular ProcessesPhoto Credit: Getty ImagesAt its core, pathology is the study of disease. Diseases occur for many reasons. But some, such as cystic fibrosis and Parkinson’s Disease, occur because of alterations that prevent cells from functioning normally.Understanding of signals and symptoms of alterations in cellular processes is a critical step in diagnosis and treatment of many diseases. For the Advanced Practice Registered Nurse (APRN), this understanding can also help educate patients and guide them through their treatment plans.For this Discussion, you examine a case study and explain the disease that is suggested. You examine the symptoms reported and explain the cells that are involved and potential alterations and impacts.To prepare:By Day 1 of this week, you will be assigned to a specific scenario for this Discussion. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.By Day 3 of Week 1Post an explanation of the disease highlighted in the scenario you were provided. Include the following in your explanation:The role genetics plays in the disease.Why the patient is presenting with the specific symptoms described.The physiologic response to the stimulus presented in the scenario and why you think this response occurred.The cells that are involved in this process.How another characteristic (e.g., gender, genetics) would change your response.Read a selection of your colleagues’ responses.By Day 6 of Week 1Respond to at least two of your colleagues on 2 different days and respectfully agree or disagree with your colleague’s assessment and explain your reasoning. In your explanation, include why their explanations make physiological sense or why they do notNote: For this Discussion, you are required to complete your initial post before you will be able to view and respond to your colleagues’ postings. Begin by clicking on the "Post
  • 2. to Discussion Question" link and then select "Create Thread" to complete your initial post. Remember, once you click on Submit, you cannot delete or edit your own posts, and you cannot post anonymously. Please check your post carefully before clicking on Submit!Submission and Grading InformationGrading CriteriaTo access your rubric:Week 1 Discussion RubricPost by Day 3 of Week 1 and Respond by Day 6 of Week 1To Participate in this Discussion:Week 1 DiscussionAssignmentPracticum Manual AcknowledgmentThe Practicum Manual describes the structure and timing of the classroom-based and practicum experiences and the policies students must follow to be successful in the nurse practitioner (NP) specialties.Field Experience: MSN Nurse Practitioner Practicum ManualClick here and follow the instructions to confirm you have downloaded and read the entire MSN Nurse Practitioner Practicum Manual and will abide by the requirements described in order to successfully complete this program.What's Coming Up in Week 2?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesNext week, you will examine alterations in the immune system and the resultant disease processes. You will also consider patient characteristics, including racial and ethnic variables, that may impact altered physiology.Practicum - Upcoming DeadlineIn the Nurse Practitioner programs of study (FNP, AGACNP, AGPCNP, and PMHNP) you are required to take several practicum courses. If you plan on taking a practicum course within the next two terms, you will need to submit your application via Meditrek .For information on the practicum application process and deadlines, please visit the Field Experience: College of Nursing: Application Process – Graduate web page.Please take the time to review the Appropriate Preceptors and Field Sites for your courses.Please take the time to review the practicum manuals, FAQs, Webinars and any required forms on the Field Experience: College of Nursing: Student Resources and Manuals web page.Field Experience: College of Nursing Quick AnswersField Experience: MSN Nurse Practitioner Practicum ManualStudent Practicum Resources: NP Student OrientationNext WeekTo go to the next week:Week 2 Week 2: Altered PhysiologyWith a place squarely in the spotlight for patients diagnosed with all manner of disease, APRNs must demonstrate not only support and compassion, but expertise to guide patients’ understanding of diagnoses and treatment plans.This expertise goes beyond an understanding of disease and sciences, such as cellular pathophysiology. APRNs must become experts in their patients, understanding their medical backgrounds, pertinent characteristics, and other variables that can be factors in their diagnoses and treatments.This week, you examine alterations in the immune system and the resultant disease processes. You consider patient characteristics, including racial and ethnic variables, and the impact they have on altered physiology.Learning ObjectivesStudents will:Evaluate cellular processes and alterations within cellular processesAnalyze alterations in the immune system that result in disease processesIdentify racial/ethnic variables that may impact physiological functioningEvaluate the impact of patient characteristics on disorders and altered physiologyLearning ResourcesRequired Readings (click to expand/reduce)Required Media (click to expand/reduce)Module 1 Assignment: Case Study AnalysisAn understanding of cells and cell behavior is a critically important component of disease diagnosis and treatment. But some diseases can be complex in nature, with a variety of factors and circumstances impacting their emergence and severity.Effective disease
  • 3. analysis often requires an understanding that goes beyond isolated cell behavior. Genes, the environments in which cell processes operate, the impact of patient characteristics, and racial and ethnic variables all can have an important impact.Photo Credit: Getty Images/Hero ImagesAn understanding of the signals and symptoms of alterations in cellular processes is a critical step in the diagnosis and treatment of many diseases. For APRNs, this understanding can also help educate patients and guide them through their treatment plans.In this Assignment, you examine a case study and analyze the symptoms presented. You identify cell, gene, and/or process elements that may be factors in the diagnosis, and you explain the implications to patient health.To prepare:By Day 1 of this week, you will be assigned to a specific case study for this Case Study Assignment. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.The Assignment (1- to 2-page case study analysis)Develop a 1- to 2-page case study analysis in which you:Explain why you think the patient presented the symptoms described.Identify the genes that may be associated with the development of the disease.Explain the process of immunosuppression and the effect it has on body systems.By Day 7 of Week 2Submit your Case Study Analysis Assignment by Day 7 of Week 2.Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted must use this formatting.Submission and Grading InformationTo submit your completed Assignment for review and grading, do the following:Please save your Assignment using the naming convention “M1Assgn+last name+first initial.(extension)” as the name.Click the Module 1 Assignment Rubric to review the Grading Criteria for the Assignment.Click the Module 1 Assignment link. You will also be able to “View Rubric” for grading criteria from this area.Next, from the Attach File area, click on the Browse My Computer button. Find the document you saved as “M1Assgn+last name+first initial.(extension)” and click Open.If applicable: From the Plagiarism Tools area, click the checkbox for I agree to submit my paper(s) to the Global Reference Database.Click on the Submit button to complete your submission.Grading CriteriaTo access your rubric:Module 1 Assignment RubricCheck Your Assignment Draft for AuthenticityTo check your Assignment draft for authenticity:Submit your Module 1 Assignment draft and review the originality report.Submit Your Assignment by Day 7 of Week 2To participate in this Assignment:Module 1 AssignmentWhat's Coming Up in Module 2?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 2, you will analyze processes related to cardiovascular and respiratory disorders. To do this, you will analyze alterations in the cardiovascular and respiratory systems and the resultant disease processes. You will also consider patient characteristics, including racial and ethnic variables, which may impact physiological functioning and altered physiology.Week 3 Knowledge Check: Cardiovascular and Respiratory DisordersIn the Week 3 Knowledge Check, you will demonstrate your understanding of the topics covered during Module 2. This Knowledge Check will be composed of a series of questions related to specific scenarios provided. It is highly recommended that you review the Learning Resources in
  • 4. their entirety prior to taking the Knowledge Check, since the resources cover the topics addressed. Plan your time accordingly.Next ModuleTo go to the next Module:Module 2Week 3: Concepts of Cardiovascular and Respiratory DisordersThe circulatory system and the respiratory system are powerful partners in health. While they work closely together in good health, a disease or disorder that manifests in one can have a significant impact on both, hampering the pair’s ability to collaborate.Cardiovascular and respiratory disease and disorders are among the most common reasons for hospital visits, and among the leading causes of fatality. Heart disease and pneumonias are among the most familiar, but a wide variety of issues can impact physiological functioning of one or both systems.This week, you examine fundamental concepts of cardiovascular and respiratory disorders. You explore common diseases and disorders that impact these systems, and you apply the key terms and concepts that help communicate the pathophysiological nature of these issues to patients.Learning ObjectivesStudents will:Analyze concepts and principles of pathophysiology across the lifespanLearning ResourcesRequired Readings (click to expand/reduce)Required Media (click to expand/reduce)Knowledge Check: Cardiovascular and Respiratory DisordersIn this exercise, you will complete a 5-essay type question Knowledge Check to gauge your understanding of this module’s content.Possible topics covered in this Knowledge Check include:myocardial infarctionendocarditismyocarditisvalvular disorderslipid panelscoagulationclotting cascadedeep vein thrombosishypertensionheart failureCOPDasthmapneumoniasPhoto Credit: Getty Images/Science Photo Library RFComplete the Knowledge Check by Day 7 of Week 3To complete this Knowledge Check:Module 2 Knowledge CheckWhat’s Coming Up in Week 4?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesNext week, you will examine the alterations in the cardiovascular and respiratory systems and the resultant disease processes through case study analysis. You will also consider patient characteristics, including racial and ethnic variables, which may impact altered physiology.Next WeekTo go to the next week:Week 4 Week 4: Alterations in the Cardiovascular and Respiratory SystemsCardiovascular and respiratory disorders can quickly become dangerous healthcare matters, and they routinely land among the leading causes of hospital admissions. Disorders in these areas are complicated by the fact that these two systems work so closely as contributors to overall health. APRNs working to form a similarly close partnership with patients must demonstrate not only support and compassion, but expertise to guide the understanding of diagnoses and treatment plans. This includes an understanding of patient medical backgrounds, relevant characteristics, and other variables that can be factors in their diagnoses and treatments.This week, you examine alterations in the cardiovascular and respiratory systems and the resultant disease processes. You also consider patient characteristics, including racial and ethnic variables, and the impact they have on altered physiology.Learning ObjectivesStudents will:Analyze processes related to cardiovascular and respiratory disordersAnalyze alterations in the cardiovascular and respiratory systems and the resultant disease processesAnalyze racial/ethnic variables that may impact physiological functioningEvaluate the impact of patient characteristics on disorders and altered physiologyLearning ResourcesRequired Readings (click to expand/reduce)Required Media (click to expand/reduce)Module 2
  • 5. Assignment: Case Study AnalysisAn understanding of the cardiovascular and respiratory systems is a critically important component of disease diagnosis and treatment. This importance is magnified by the fact that these two systems work so closely together. A variety of factors and circumstances that impact the emergence and severity of issues in one system can have a role in the performance of the other.Effective disease analysis often requires an understanding that goes beyond these systems and their capacity to work together. The impact of patient characteristics, as well as racial and ethnic variables, can also have an important impact.Photo Credit: yodiyim / Adobe StockAn understanding of the symptoms of alterations in cardiovascular and respiratory systems is a critical step in diagnosis and treatment of many diseases. For APRNs this understanding can also help educate patients and guide them through their treatment plans.In this Assignment, you examine a case study and analyze the symptoms presented. You identify the elements that may be factors in the diagnosis, and you explain the implications to patient health.To prepare:By Day 1 of this week, you will be assigned to a specific case study scenario for this Case Study Assignment. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.Assignment (1- to 2-page case study analysis)In your Case Study Analysis related to the scenario provided, explain the followingThe cardiovascular and cardiopulmonary pathophysiologic processes that result in the patient presenting these symptoms.Any racial/ethnic variables that may impact physiological functioning.How these processes interact to affect the patient.By Day 7 of Week 4Submit your Case Study Analysis Assignment by Day 7 of Week 4Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted must use this formatting.Submission and Grading InformationTo submit your completed Assignment for review and grading, do the following:Please save your Assignment using the naming convention “M2Assgn+last name+first initial.(extension)” as the name.Click the Module 2 Assignment Rubric to review the Grading Criteria for the Assignment.Click the Module 2 Assignment link. You will also be able to “View Rubric” for grading criteria from this area.Next, from the Attach File area, click on the Browse My Computer button. Find the document you saved as “M2Assgn+last name+first initial.(extension)” and click Open.If applicable: From the Plagiarism Tools area, click the checkbox for I agree to submit my paper(s) to the Global Reference Database.Click on the Submit button to complete your submission.Grading CriteriaTo access your rubric:Module 2 Assignment RubricCheck Your Assignment Draft for AuthenticityTo check your Assignment draft for authenticity:Submit your Module 2 Assignment draft and review the originality report.Submit Your Assignment by Day 7 of Week 4To participate in this Assignment:Module 2 AssignmentWhat's Coming Up in Module 3?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 3, you will analyze processes related to gastrointestinal and hepatobiliary disorders through case study analysis. To do this, you will analyze alterations in the relevant systems and the resultant disease processes. You will also consider patient characteristics, including racial and ethnic
  • 6. variables, which may impact physiological functioning and altered physiology.Week 5 Knowledge Check: Gastrointestinal and Hepatobiliary DisordersIn Week 5 Knowledge Check, you will demonstrate your understanding of the topics covered during Module 3. This Knowledge Check will be composed of a series of questions related to specific scenarios provided. It is highly recommended that you review the Learning Resources in their entirety prior to taking the Knowledge Check since the resources cover the topics addressed. Plan your time accordingly.Next ModuleTo go to the next Module:Module 3Week 5: Concepts of Gastrointestinal and Hepatobiliary DisordersPatients of gastrointestinal and hepatobiliary disorders often face life-altering changes, including changes to diet, new treatment regimens, and more. For some disorders, treatments can include surgery.Gastrointestinal conditions, such as ulcers, diverticulitis, and pancreatitis, often cause varying levels of pain and discomfort. Hepatobiliary conditions can also bring significant changes to patient routines and well-being.This week, you examine fundamental concepts of gastrointestinal and hepatobiliary disorders. You explore common disorders in these categories, and you apply the key terms and concepts that help communicate the pathophysiological nature of these issues to patients.Learning ObjectivesStudents will:Analyze concepts and principles of pathophysiology across the life spanLearning ResourcesRequired Readings (click to expand/reduce)Required Media (click to expand/reduce)Knowledge Check: Gastrointestinal and Hepatobiliary DisordersIn this exercise, you will complete a 5-essay type question Knowledge Check to gauge your understanding of this module’s content.Possible topics covered in this Knowledge Check include:UlcersHepatitis markersAfter HP shotsGastroesophageal Reflux DiseasePancreatitisLiver failure—acute and chronicGall bladder diseaseInflammatory bowel diseaseDiverticulitisJaundiceBilirubinGastrointestinal bleed – upper and lowerHepatic encephalopathyIntra-abdominal infections (e.g., appendicitis)Renal blood flowGlomerular filtration rateKidney stonesInfections – urinary tract infections, pyelonephritisAcute kidney injuryRenal failure – acute and chronicPhoto Credit: Getty ImagesComplete the Knowledge Check By Day 7 of Week 5To complete this Knowledge Check:Module 3 Knowledge CheckWhat's Coming Up in Module 4?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 4, you will analyze processes related to endocrine disorders. To do this, you will analyze alterations in the relevant systems and the resultant disease processes. You will also consider patient characteristics, including racial and ethnic variables, that may impact physiological functioning and altered physiology.Week 6 Knowledge Check: Endocrine DisordersIn the Week 6 Knowledge Check, you will demonstrate your understanding of the topics covered during Module 4. This Knowledge Check will be composed of a series of questions related to specific scenarios provided. It is highly recommended that you review the Learning Resources in their entirety prior to taking the Knowledge Check, since the resources cover the topics addressed. Plan your time accordingly.Also, during this week you will take your Midterm Exam. Please make sure to finalize and complete your Knowledge Check prior to completing your exam.Next ModuleTo go to the next Module:Module 4Week 6: Concepts of Endocrine DisordersEndocrine disorders are complex matters, and there is not always a one-size-fits-all treatment. Particularly in matters requiring the adjustment of hormone
  • 7. levels, treatment may require a custom approach tailored to individual patients. An understanding of these complications is essential to supporting these individual treatment plans.This week, you examine alterations in the endocrine system and the resultant disease processes. You also consider patient characteristics, including racial and ethnic variables, and the impact they have on altered physiology.Learning ObjectivesStudents will:Analyze concepts and principles of pathophysiology across the lifespanLearning ResourcesRequired Readings (click to expand/reduce)Required Media (click to expand/reduce)Optional Resources (click to expand/reduce)Knowledge Check: Endocrine DisordersIn this exercise, you will complete a 5-essay type question Knowledge Check to gauge your understanding of this module’s content.Possible topics covered in this Knowledge Check include:DiabetesHyper- and hypothyroidismAdrenal disordersParathyroidism (hyper and hypo)Checks & balances / negative feedbackSyndrome of Inappropriate Antidiuretic HormonePheochromocytosisDiabetes insipidusDiabetic ketoacidosisPhoto Credit: Getty Images/Science Photo Library RF(Note: It is strongly recommended that you take the Knowledge Check at least 48 hours before taking the Midterm Exam.)Complete the Knowledge Check By Day 5 of Week 6To complete this Knowledge Check:Module 4 Knowledge CheckMidterm ExamThis 101-question exam is a test of your knowledge in preparation for your certification exam. No outside resources, including books, notes, websites, or any other type of resource, are to be used to complete this exam. You are expected to comply with Walden University’s Code of Conduct.This exam will be on topics covered in Weeks 1, 2, 3, 4, 5, and 6. Prior to starting the exam, you should review all of your materials. This exam is timed with a limit of 2 hours for completion. When time is up, your exam will automatically submit.(Note: It is strongly recommended that you take the Knowledge Check at least 48 hours before taking the Midterm exam.)Photo Credit: Getty ImagesTo prepare:To help you review for your midterm exam, access the Midterm Exam Review document found in this week's Learning Resources as well as any Knowledge Check feedback you might have received. (Note: You will also need to review all of your materials from each of these weeks to also help you better prepare for your midterm.)By Day 7 of Week 6Submit your Midterm Exam.To complete your exam:Midterm ExamWhat’s Coming Up in Module 5?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 5, you will analyze processes related to neurological and musculoskeletal disorders through case study analysis. To do this, you will analyze alterations in the relevant systems and the resultant disease processes. You will also consider patient characteristics, including racial and ethnic variables, which may impact physiological functioning and altered physiology.Week 7 Knowledge Check: Neurological and Musculoskeletal DisordersIn the Week 7 Knowledge Check, you will demonstrate your understanding of the topics covered during Module 5. This Knowledge Check will be composed of a series of questions related to specific scenarios provided. It is highly recommended that you review the Learning Resources in their entirety prior to taking the Knowledge Check, since the resources cover the topics addressed. Plan your time accordingly.Next ModuleTo go to the next Module:Module 5Week 7: Concepts of Neurological and Musculoskeletal Disorders – Part 1Anatomists often use the analogy of a house to explain the human body, with skeletal systems, respiratory systems, and circulatory systems represented as a home’s framing
  • 8. structure, ventilation, and piping, respectively. Such analogies further emphasize the point that relationships between systems can result in complications when issues arise in one system.With hundreds of diseases that can impact the brain, spine, and nerves, neurological disorders represent a complicated array of issues that present significant health concerns. Disorders such as strokes and Parkinson’s disease not only affect the nervous system, however; they can have secondary impacts in other areas, especially the musculoskeletal system.This week, you examine fundamental concepts of neurological disorders. You explore common disorders that impact these systems and you apply the key terms and concepts that help communicate the pathophysiological nature of these issues to patients.Learning ObjectivesStudents will:Analyze concepts and principles of pathophysiology across the lifespanLearning ResourcesRequired Readings (click to expand/reduce)Required Media (click to expand/reduce)Knowledge Check: Neurological and Musculoskeletal DisordersIn this exercise, you will complete a 5-essay type question Knowledge Check to gauge your understanding of this module’s content.Possible topics covered in this Knowledge Check include:StrokeMultiple sclerosisTransient Ischemic AttackMyasthenia gravisHeadacheSeizure disordersHead injurySpinal cord injuryInflammatory diseases of the musculoskeletal systemOsteoporosisOsteopeniaBursitisTendinitisGoutLyme DiseaseSpondylosisFracturesParkinson’sAlzheimer’sThree basic bone- formations:OsteoblastsOsteocytesOsteoclastsPhoto Credit: Getty Images/Science Photo LibraComplete the Knowledge Check By Day 7 of Week 7To complete this Knowledge Check:Module 5 Knowledge CheckNext WeekTo go to the next week:Week 8Week 8: Concepts of Neurological and Musculoskeletal Disorders – Part 2As homeowners know all too well, there is a continuous need for maintenance and repair. Some efforts are precautionary in nature, while others are the result of issues that surface over time.Similarly, musculoskeletal disorders can develop over time. For some disorders, such as osteoporosis, precautionary treatments are a potential option. But much like issues that surface in a home over time, many musculoskeletal issues can be very serious concerns, and they can have a significant impact on patients’ lives.This week, you continue to examine fundamental concepts of neurological and musculoskeletal disorders. You explore common disorders that impact these systems and you apply the key terms and concepts that help communicate the pathophysiological nature of these issues to patients.Learning ObjectivesStudents will:Analyze processes related to neurological and musculoskeletal disordersIdentify racial/ethnic variables that may impact physiological functioningEvaluate the impact of patient characteristics on disorders and altered physiologyLearning ResourcesNote: The below resources were first presented in Week 7. If you have previously reviewed them, you are encouraged to read or view them again here. Required Readings (click to expand/reduce)Required Media (click to expand/reduce)Module 5 Assignment: Case Study AnalysisAn understanding of the neurological and musculoskeletal systems is a critically important component of disease and disorder diagnosis and treatment. This importance is magnified by the impact that that these two systems can have on each other. A variety of factors and circumstances affecting the emergence and severity of issues in one system can also have a role in the performance of the other.Effective
  • 9. analysis often requires an understanding that goes beyond these systems and their mutual impact. For example, patient characteristics such as, racial and ethnic variables can play a role.Photo Credit: jijomathai - stock.adobe.comAn understanding of the symptoms of alterations in neurological and musculoskeletal systems is a critical step in diagnosis and treatment. For APRNs this understanding can also help educate patients and guide them through their treatment plans.In this Assignment, you examine a case study and analyze the symptoms presented. You identify the elements that may be factors in the diagnosis, and you explain the implications to patient health.To prepare:By Day 1 of this week, you will be assigned to a specific case study scenario for this Case Study Assignment. Please see the “Course Announcements” section of the classroom for your assignment from your Instructor.Assignment (1- to 2-page case study analysis)In your Case Study Analysis related to the scenario provided, explain the following:Both the neurological and musculoskeletal pathophysiologic processes that would account for the patient presenting these symptoms.Any racial/ethnic variables that may impact physiological functioning.How these processes interact to affect the patient.Day 7 of Week 8Submit your Case Study Analysis Assignment by Day 7 of Week 8.Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The sample paper provided at the Walden Writing Center provides an example of those required elements (available at https://academicguides.waldenu.edu/writingcenter/templates). All papers submitted must use this formatting.Submission and Grading InformationTo submit your completed Assignment for review and grading, do the following:Please save your Assignment using the naming convention “M5Assgn+last name+first initial.(extension)” as the name.Click the Module 5 Assignment Rubric to review the Grading Criteria for the Assignment.Click the Module 5 Assignment link. You will also be able to “View Rubric” for grading criteria from this area.Next, from the Attach File area, click on the Browse My Computer button. Find the document you saved as “M5Assgn+last name+first initial.(extension)” and click Open.If applicable: From the Plagiarism Tools area, click the checkbox for I agree to submit my paper(s) to the Global Reference Database.Click on the Submit button to complete your submission.Grading CriteriaTo access your rubric:Module 5 Assignment RubricCheck Your Assignment Draft for AuthenticityTo check your Assignment draft for authenticity:Submit your Module 5 Assignment draft and review the originality report.Submit Your Assignment by Day 7 of Week 8To participate in this Assignment:Module 5 AssignmentWhat's Coming Up in Module 6?Photo Credit: [BrianAJackson]/[iStock / Getty Images Plus]/Getty ImagesIn Module 6, you will identify processes related to psychological disorders. You will also examine the neurobiology of various psychological issues and consider variables that may impact physiological functioning and altered physiology.