The document discusses nuclear reactors, including their basic components and functions. It describes how nuclear fission reactions produce energy in a reactor's core through a sustained chain reaction, using elements like U-235 as fuel. It also notes safety concerns around nuclear reactors, mentioning past disasters like Chernobyl. The document aims to explain the basic workings and elements of nuclear reactors.
A presenation on Nuclear Power Plant Presentation.Fission is the splitting of a nucleus into two or more separate nuclei of comparable mass and this process takes place in Nuclear Power Plant
nuclear power generation
types of nuclear reactor
position in india
waste management of nuclear waste
generation of nuclear reactor
advantages and disadvantages
A presenation on Nuclear Power Plant Presentation.Fission is the splitting of a nucleus into two or more separate nuclei of comparable mass and this process takes place in Nuclear Power Plant
nuclear power generation
types of nuclear reactor
position in india
waste management of nuclear waste
generation of nuclear reactor
advantages and disadvantages
Contents:
Nuclear Technology.
Atom.
Nuclear Energy.
Splitting the uranium atom.
chain reaction.
Types of nuclear reaction.
Nuclear fission.
Nuclear fusion.
Where does energy comes from.
Construction & Working of Nuclear Reactors.
Nuclear Weapons.
Types of Fission Bombs.
Gun Triggered fission bombs.
Implosion Triggered fission bombs.
Hydrogen bomb & Functioning & its effects.
Advantages and Disadvantages
The Future of Nuclear Energy
Nuclear energy & its Pros and cons and disasters.Sunesh Malik
A detailed presentation on Nuclear reactions - fission & fusion and how they are used to form energy. Pros and cons of Nuclear energy and perminent examples.
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A nuclear power plant is a thermal power station in which the heat source is a nuclear reactor. As in a conventional thermal power station the heat is used to generate steam which drives a steam turbine connected to a generator which produces electricity.
Contents:
Nuclear Technology.
Atom.
Nuclear Energy.
Splitting the uranium atom.
chain reaction.
Types of nuclear reaction.
Nuclear fission.
Nuclear fusion.
Where does energy comes from.
Construction & Working of Nuclear Reactors.
Nuclear Weapons.
Types of Fission Bombs.
Gun Triggered fission bombs.
Implosion Triggered fission bombs.
Hydrogen bomb & Functioning & its effects.
Advantages and Disadvantages
The Future of Nuclear Energy
Nuclear energy & its Pros and cons and disasters.Sunesh Malik
A detailed presentation on Nuclear reactions - fission & fusion and how they are used to form energy. Pros and cons of Nuclear energy and perminent examples.
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A nuclear power plant is a thermal power station in which the heat source is a nuclear reactor. As in a conventional thermal power station the heat is used to generate steam which drives a steam turbine connected to a generator which produces electricity.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
2. Prepared By :- Rudra Pratap Sen
Roll No :- 3029
Student Id :- 2020-574
Section :- Day
Paper
3. Nuclear Reactor
Types of Nuclear Reactor
Nuclear Fission Reaction
U-235 Fission
Basic Elements of a Nuclear Reactor
Dangers Of Nuclear Reactor
Acknowledgement
4. What is a Nuclear Reactor ?
A Nuclear Reactor is essentially a device wherein a neutron-induced self-sustained chain
reaction involving fission of heavy elements take place. The purpose of the reactor is (i)
initiate nuclear fission reaction, (ii) control these reactions, and (iii) extract the energy
produced by fission. The control of neutrons is the key to the functioning of a nuclear
reactor.
Nuclear Reactors are used at Nuclear Power Plants , Nuclear Marine Propulsions .
Chicago Pile-1 (CP-1) was the world's first artificial nuclear reactor. On 2 December 1942,
the first human-made self-sustaining nuclear chain reaction was initiated in CP-1, during an
experiment led by Enrico Fermi. It was then called a uranium-carbon pile.
India’s first Research Nuclear Reactor became operational in August 1956 at Trombay
Campus of Bhaba Atomic Research Centre . It was decommissioned in 2009. The first
nuclear power reactors built in India were two BWRs at Tarapur, constructed by GE as
turnkey projects through Indo-US cooperation.
Fig-1:- First Reactor
construction in 1942
Fig-2:- ‘APSARA’ , India’s
first research nuclear
reactor
5. There are several types of Nuclear Reactors which are used to
generate heat energy at power plants . Main types of reactors
follows as
Pressurized water reactor (PWR)
Boiling water reactor (BWR)
Advanced gas-cooled reactor (AGR)
Light water graphite-moderated reactor (LWGR)
Fast neutron reactor (FNR)
Pressurized heavy water reactor (PHWR)
High temperature gas-cooled reactor (HTGR)
Among these various types of Reactors PWR is widely used . Fig-3:- Schematic of a Pressurized
Water Reactor
6. The phenomenonof the division or disintegration of a heavy nucleus into two nuclei of
comparable masses is termed nuclear fission. It is analogous to cell division in biology. Nuclear
Fission can either be rapid or controlled . Controlled nuclear fission is used in Nuclear Reactor.
Nuclear fission of heavy elements was discovered on 19th December 1938 by German chemist
Otto Hahn & his assistant Fritz Strassman in co-operationwith Austrian Swedish physicist Lise
Meitner .
The chemical element isotopes that can sustain a fission chain reaction are called nuclear fuel,
are said to be fissile. The most common nuclear fuels are 92
235𝑈 & 94
239𝑃𝑢 . In a nuclear reactor or
nuclear weapon, the overwhelming majority of fission events are induced by bombardment with
another particle, a neutron which is itself produced by prior fission events.
Nuclear fission can occur without neutron bombardment as a type of radioactive decay. This
type of fission ( Called spontaneous fission) is rare except in a few heavy isotopes.
Fig-4:- Uranium metal
highly enriched in
uranium-235
Fig-5:- A 99.96% pure ring
of plutonium
7. 92
235
𝑈 FISSION
Uranium-235 is the most used nuclear fuel . When a slow neutron ( having
therefore a high value for capture cross-section ) bombardedinto a
Uranium-235 atom , a highly unstable isotope of Uranium , 92
236
𝑈 is created .
Instantly this isotope breaks apart and creates two daughter nuclei which
follows as 56
141
𝐵𝑎 & 36
92
𝐾𝑟 . Three neutron is also created & a huge amount of
energy which is nearly 200 MeV is released.That three neutrons also take
part into the reaction & bombards another Uranium-235 atoms. This process
takes place rapidly and a chain reactions starts. As a result we get a
overwhelmingamount of energy in a fractions of seconds.
The Reaction follows as :-
92
235
𝑈 + 0
1
𝑛 -> 92
236
𝑈 -> 56
141
𝐵𝑎 + 36
92
𝐾𝑟 + 30
1
𝑛 + 200 MeV
This reactions happens in the core of a nuclear reactor in a controlled way.
Natural Uranium contains 0.7% of U-235 isotope. The remaining 99.3% being
U-238, which is not fissionableby thermal neutrons.One of the common
methods to enrich natural uranium with U-235 isotope is the gaseous
diffusion through a porous barrier. Naturally enriched uranium by U-235
isotope is also used in many reactors. Fig-6:- Chain Reaction of U-235 Fission
Fig-5:- U-235 fission by thermal neutron
8. All types of nuclear reactors contain the following basic essential elements or component
I. Fuels:- Fuel undergoes fission and thereby supplies neutrons for inducing further fissions. The commonly used
reactor fuels are the Uranium isotope U-235 , Thorium isotope Th-232 , Plutonium isotope Pu-239 .
II. Reflector:- Some of the neutrons produced by fission will leak out of the reactor and so not be part of the chain
reaction. Leakage is a surface effect, its magnitude is proportional to the squarer of a typical reactor dimension. A
reflector is placed around the reactor core to prevent neutrons from escaping from the core. Efficiency of a
reflector increases rapidly with its thickness. Good moderators are usually good reflectors.
III. Moderator:- The neutrons produced by fission are fast, with kinetic energy of about 2 MeV. However, Fission is
induced most effectively by thermal neutrons. The fast neutrons can be slowed down by mixing the uranium fuel
with a substance – called Moderator –that has two properties: It is effective in slowing down neutrons via elastic
collisions, and it does not remove neutrons from the core by absorbing them so that they do not result in fission.
Good moderators should have a large scattering cross section and small neutron capture cross section. The usual
moderators are : Graphite , Heavy Water , Beryllium Oxide , Hydrides of metal and organic liquids. The nuclei of
these materials hardly absorbs neutron.
IV. Cooling System:- The cooling system in a reactor helps to control the temperature of the fuel element and
transport the heat generated by fission to the heat engine. There are four types of possible coolants. These are (i)
Gases: air , carbon-di-oxide, helium or steam, (ii) Water type liquids: water or heavy water, (iii) Molten Metals: Hg,
Na, K, Pb, Bi & (iv) fused salts. Each type has its own merits & demerits.
V. Safety System:- Safety of reactor is accomplished by surrounding the reactor with massive layers of concrete and
lead and by providing completely closed coolant circuits.
9. VI. Control Rods:- An important reactor parameter is the ratio of the number of neutrons present at the conclusion of a
particular generation to the number present at the beginning of that generation. In Fig-7 the multiplication factor is
1000/1000, or exactly unity. For k=1 , the operation of reactor is said to be exactly critical, which is what we wish it to be for
steady power operation. Reactors are actually designed so that they are inherently supercritical (k>1) . The multiplication
factor is then adjusted to critical operation by inserting control rods into the reactor core . These rods, containing a material
such as cadmium that absorbs neutrons readily, can be inserted farther to reduce the operating power level and withdrawn
to increase the power level or to compensate for the tendency of reactors to go subcritical as (neutron absorbing) fission
products build up I the core during continued operation.
Fig-7:- Neutron Bookkeeping in a reactor
*NOTE* The Neutron Capture Problem:- As fast (2 MeV) neutrons generated by
fissions are slowed down in the moderator to thermal energies (about 0.04 MeV)
they must pass through acritical energy interval (from 1 to 100 MeV) in which
they are particularly susceptible to nonfission capture by U-238 nuclei. Such
resonance capture , which results in the emission of a gamma ray, removes the
neutron from the fission chain. To minimize such nonfission capture, the uranium
fuel and the moderator are not intimately mixed but rather are placed in
different regions of the reactor volume.
VII. Steam Generator:- It is the part where heat is exchanged with water and water become vapor.
Pressurized vapor is send to turbine through a narrow channel . Steam turbines are connected to
dynamos which generates electricity.
10. Nuclear Power is no doubt a greener energy option . We often see smoke coming out of big
chimneys of nuclear power plant . But that is vaporized water which is used to cool the reactor
core . Most of the water used in reactor is reused in the process. Only a small amount of fuel in
enough to generate sufficient amount of energy . But like other energy resources it has its own
demerits. Though we can tell Nuclear Energy pollution free to most extent but it is hazardous if it
is not handled properly. Nuclear Reactors produces radioactive plutonium isotopes as nuclear
waste . Till today nuclear waste disposal is major concern for nations worldwide. Mishandled
nuclear waste can easily contaminate environment which can have a far reaching bad effects on
the living organism of earth.
Fig-8:- Nuclear waste disposal
in a nuclear power plant
Another concern for nuclear reactor is nuclear disasters . Sudden failure of
safety system , uncontrolled power surge , failure of cooling system , even human errors
can cause a severe nuclear disaster . The Chernobyl disaster was a nuclear accident that
occurred on 26 April 1986 at the No. 4 reactor in the Chernobyl Nuclear Power Plant, near
the city of Pripyat in the north of the Ukrainian SSR in the Soviet Union. It is one of only
two nuclear energy accidents rated at seven—the maximum severity—on the International
Nuclear Event Scale, the other being the 2011 Fukushima nuclear disaster in Japan.
Fig-9:- Chernobyl Nuclear Disaster
Keeping in mind that fossil fuels will not be available at near future we
have to make efforts to make nuclear energy as safe as possible .
11. Principles of Physics ; International Student
Version ; Tenth Edition by Haliday, Resnick,
Walker
Modern Atomic and Nuclear Physics ; Fourth
Edition by A.B.Gupta
https://en.Wikipedia.org
https://www.google.com
https://www.barc.gov.in
https://world-nuclear.org