The document discusses a conference call on selected zoonotic diseases from November 4, 2009. It provides updates on H1N1 influenza, brucellosis in the United States, and bat-associated rabies virus in Arizona. It also discusses oral rabies vaccination opportunities, complexities, and challenges in North America.

1. Selected Zoonotic Diseases Conference Call November 4, 2009

2. Carol Rubin, DVM, MPH , National Center for Zoonotic, Vector-borne, and Enteric Diseases, CDC 404-639-7378 [email_address] Selected Zoonotic Diseases Conference Call November 4, 2009 Update on H1N1

4. Kendra E. Stauffer, DVM ; Bacterial Zoonoses Branch, CDC 404-639-3435 kstauffer@cdc.gov Selected Zoonotic Diseases Conference Call November 4, 2009 The Changing Face of Brucellosis in the United States http ://www.cdc.gov/Features/HuntingSafety/Brucellosis_and_HogHunters_508.pdf Additional zoonotic resources for hunters from the AVMA include: http://www.avma.org/public_health/zoonotic_risks/hunters.asp http://www.avma.org/public_health/zoonotic_risks/hunters_precautions.asp

5. Steven Baty, DVM, MPH, Arizona Department of Health Services 602-364-3875 batys@azdhs.gov Andrea McCollum, PhD, Poxvirus and Rabies Branch, CDC 404-639-4164 amccollum@cdc.gov Selected Zoonotic Diseases Conference Call November 4, 2009 Bat-associated Rabies Virus in Skunks and Foxes, Flagstaff, Arizona 2009

6. Bat-associated Rabies Virus Variant Arizona, 2009 Steven Baty, DVM, MPH Arizona Department of Health Services EIS Field Assignments Branch, CDD, OWCD Andrea McCollum, PhD Division of Viral and Rickettsial Diseases, CDC

10. Big Brown Bat Variant Grey Fox Variant South-Central Skunk Variant

11. Number of cases Wildlife Rabies Cases Arizona 1999 – 2009 Year

12. Flagstaff

14. Wildlife Rabies Cases Coconino County 1999 – 2009 Number of cases Year

15. Wildlife Rabies Cases Coconino County November 2008 –October 2009 Oral Rabies Vaccine (ORV) Trap Vaccinate Release (TVR) Quarantine Number of cases Month

26. William H. Wunner, PhD, Professor and Director of Outreach Education and Technology Training; The Wistar Institute; 215-898-3854 wunner@wistar.org Deborah J. Briggs, PhD, Adjunct Professor, College of Veterinary Medicine, Kansas State University briggs@vet.k-state.edu Selected Zoonotic Diseases Conference Call November 4, 2009 Overview of special collections on papers on rabies appearing in the journals Vaccine and PLoS NTD

27. Richard B. Chipman, National Rabies Management Program, USDA, APHIS, Wildlife Services 518-477-5628 Richard.B.Chipman@ aphis.usda.gov Selected Zoonotic Diseases Conference Call November 4, 2009 Oral vaccination opportunities, complexities and challenges in North America

28. Rich Chipman Asst. Rabies Management Coordinator USDA, APHIS, WS-National Rabies Management Program

29. 10 Minute Paper Summary “ Oral Rabies Vaccination in North America: Opportunities, Complexities and Challenges” (In Press) Public Library of Science Neglected Tropical Diseases Dennis Slate, Timothy P. Algeo, Kathleen M. Nelson, Richard B. Chipman, Dennis Donovan, Jesse D. Blanton, Michael Niezgoda, and Charles E. Rupprecht

30. Background

31. Diverse meso-carnivore community…

32. U.S. Rabies Virus Variants 2008

33. North American borders and key meso-carnivore ranges Coyote Red fox Gray fox Raccoon Striped skunk Bobcat

34. In 1969, Dr. George Baer, then at CDC, and associates prove oral rabies vaccination feasible in foxes… Baer, G.M., M.K. Abelseth, and J.G. Debbie. (1971). Oral vaccination of foxes against rabies. Am. J. of Epidemiol. 93:487-490. Oral Rabies Vaccination from proof of concept To control reality

36. Wildlife Management Agencies Public Health Agencies Agriculture Agencies Universities Oral Rabies Vaccination Wildlife Health Agriculture

37. Collaboration & Strategic Planning

40. … areas for collaboration North American Rabies Management Plan Information transfer Research Surveillance and monitoring Rabies prevention and control Wildlife Public Health Agriculture

42. Enhanced Surveillance

45. Enhanced Surveillance WS Trap & Euthanize WS Firearms WS Road Kill Non-WS Collection 2009 Source Types

46. Trap-Vaccinate-Release Raccoon Variant Rabies

47. Oral Rabies Vaccination

49. ORV Zones 2009 gray fox coyote raccoon

50. ORV in the U.S. (2009)

54. Year Rabies Cases ORV zone 1995 2000- 2007 Rabies case in 2001 and 2004 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 166 58 21 6 5 10 0 1 0 0 1 0 0 0 0 0 Canine Rabies in Coyote, South Texas W e b b D u v a l F r i o S t a r r B e e U v a l d e B e x a r H i d a l g o K i n n e y Z a v a l a D i m m i t M e d i n a L a S a l l e K e n e d y Z a p a t a M a v e r i c k B r o o k s G o l i a d L a v a c a A t a s c o s a D e W i t t V i c t o r i a W i l s o n L i v e O a k M c M u l l e n J i m H o g g G o n z a l e s N u e c e s K a r n e s K l e b e r g J a c k s o n R e f u g i o C a m e r o n J i m W e l l s W i l l a c y G u a d a l u p e S a n P a t r i c i o C a l h o u n A r a n s a s W e b b D u v a l F r i o S t a r r B e e U v a l d e B e x a r H i d a l g o K i n n e y Z a v a l a D i m m i t M e d i n a L a S a l l e K e n e d y Z a p a t a M a v e r i c k B r o o k s G o l i a d L a v a c a A t a s c o s a D e W i t t V i c t o r i a W i l s o n L i v e O a k M c M u l l e n J i m H o g g G o n z a l e s N u e c e s K a r n e s K l e b e r g J a c k s o n R e f u g i o C a m e r o n J i m W e l l s W i l l a c y G u a d a l u p e S a n P a t r i c i o C a l h o u n A r a n s a s ORV begins W e b b D u v a l F r i o S t a r r B e e U v a l d e B e x a r H i d a l g o K i n n e y Z a v a l a D i m m i t M e d i n a L a S a l l e K e n e d y Z a p a t a M a v e r i c k B r o o k s G o l i a d L a v a c a A t a s c o s a D e W i t t V i c t o r i a W i l s o n L i v e O a k M c M u l l e n J i m H o g g G o n z a l e s N u e c e s K a r n e s K l e b e r g J a c k s o n R e f u g i o C a m e r o n J i m W e l l s W i l l a c y G u a d a l u p e S a n P a t r i c i o C a l h o u n A r a n s a s

56. ??Gray fox var. TX

57. 125,278 by baits air 4,322 by baits ground ORV targeting gray fox TVR targeting skunks Big brown bat clades

58. Complexities, and other Considerations

60. Seroconversion Post-ORV

61. Skunks infected with raccoon rabies Skunks

62. Raccoon Rabies Contingency Actions in FY 2009

64. WS ORV (75 baits/km 2 ) WS ORV (150 baits/km 2 ) NYSDOH ORV (75 baits/km 2 ) TVR area Border Contingency Action areas 2009

67. Trap-Vaccinate-Release Raccoon Variant Rabies in ORV Zone

70. Susan Moore, Rabies Laboratory Manager, K-State Rabies Laboratory 785-532-4472 smoore@vet.ksu.edu Selected Zoonotic Diseases Conference Call November 4, 2009 Rabies specific antibodies: measuring surrogates of protection against a fatal disease

71. Rabies Specific Antibodies: Measuring Surrogates of Protection Against a Fatal Disease Susan M. Moore and Cathleen A. Hanlon

73. Serum Neutralization test ELISA test

77. Selected Zoonotic Diseases Conference Call November 4, 2009