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Cognitive & Biopsychological
        Perspectives


Structure & Functioning of Neuron

             (Neuron 1)
Structure & Functioning of Neuron

 To provide a basic understanding of:

• The structure of the neuron
• Transmission of the neural impulse along
  the neuron
NERVOUS
                                    SYSTEM


        Central Nervous                                    Peripheral Nervous
         System (CNS)                                         System (PNS)



                          Spinal        Somatic System             Autonomic Nervous
BRAIN                      Cord
                                       (Motor & Sensory)
                                                                      System (ANS)
                                          Voluntary



                                                                                 Sympathetic


                                                                                Parasympathetic
Side View
Structure of the

   Neuron
Structure of Neuron
The Neuron

• Resting Potential

• Threshold

• Action Potential

• ‘All or none’ law
The Neuron

• Sodium ions (Na+)

• Potassium ions (K+)

• Chloride ions (CL-)



• (Also, Protein ions An-)
Resting Potential
Axon




       -   -       -   -       -       -
       -   -   -       -   -       -       -
Distribution of Negative Ions

Axon

         CL- CL-        CL-         CL-
              An- CL- An-            An-
                  An-   An-          CL-

           CL-        CL-     CL-    CL-



An- Trapped inside axon
CL- greater concentration outside axon than inside
Distribution of Positive Ions

Axon



       Na+    Na+ Na+ Na+ K+
          Na+ K+    K+    K+
       K+    K+ Na+    K+    K+
          Na+     Na+            K+     Na+         Na+




K+     greater concentration inside axon than outside
Na+    greater concentration outside axon than inside
Resting Potential


The resting potential is maintained by:

1. Selectively Permeable Membrane

2. Sodium – Potassium Pump
Resting Potential
Axon



       Na+    Na+ Na+ Na+ K+
          Na+ K+    K+    K+
       K+    K+ Na+    K+    K+
          Na+     Na+           K+    Na+         Na+




  3 Sodium ions (Na+) pumped out for every 2 Potassium ions (K+)
  drawn in
Propagation


Propagation of the action potential
refers to the transmission of the action
potential along the axon.
Propagation
Axon



       +
       +++       -       -       -       -       -
       +++   -       -       -       -       -       -
       +
Propagation
Axon




       -       -    +++ -       -       -       -
       -   -       - +++    -       -       -
Propagation
Axon




       -       -   -       -   -     +++
           -   -   -      -    -   - +++
Saltatory Conduction


Saltatory conduction is the
transmission of the impulse
from node to node
"All or None" law

If the threshold is reached the neuron
will 'fire' (ie a neural impulse will
occur) if it is not reached the neuron
will not fire

 • Therefore, the size and shape of the
   action potential are independent of
   the intensity of the stimulus that
   initiated it
Refractory Period

   For a few milliseconds following a neural
   impulse the membrane is temporarily
   unexcitable and the axon cannot be fired
   again regardless of the strength of the
   stimulus.

This interval is known as the
           Absolute Refractory period
Refractory Period

Following the Absolute Refractory period

• there is a short period of time just before
  the membrane returns to normal during
  which the neuron will fire but a stronger
  than normal stimulus is required

• This period of time is called the
  Relative Refractory period
Neuron Plasticity & Age

 The structure of the neuron is fairly
   ‘plastic’, that is the fibres of the
neuron can increase or decrease their
  branching pattern as a function of
    age, experience and chemical
               influences.
Dendritic Growth
Glia (Neuroglia)

• Glia are the other main component of
  the nervous system besides neurons

• Occupy about the same total space as
  neurons

• They do not transmit information
Glia

Functions

• Remove waste
• Fill space left by dead neurons (form
  scar tissue)
• Build the myelin sheath
 - Schwann cells (PNS)
 - Oligodendrocytes (CNS)
Spinal Research


Raisman (1997)

• Olfactory cells from the nose (although
  CNS cells) can regenerate and form
  functional connections after damage
Spinal Research

Raisman (1997)
• Studies using Schwann sheath, found
  although they provide guidance to a
  regenerating spinal cord, the cord can
  not make the connection at the other
  end into the oligodendrocyte

• Olfactory cells were able to make that
  connection.
EEG

Electroencephalograph (EEG)
  Machine that records the electrical activity of the
  brain via electrodes placed on the surface of the
  scalp


Electroencephalogram (EEG)
      Trace or record of the electrical activity of the
      brain
Brain Waves
References

Carlson, N. (2010). Physiology of Behavior, (10th
      ed). London: Allyn & Bacon.

Kalat, J. (2009). Biological Psychology, (10th ed).
       Belmont, California: Wadsworth.

Pinel, J.P. (2008). Biopsychology, (7th ed).
       London: Allyn & Bacon.

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Neuron lect1 -handout

  • 1. Cognitive & Biopsychological Perspectives Structure & Functioning of Neuron (Neuron 1)
  • 2. Structure & Functioning of Neuron To provide a basic understanding of: • The structure of the neuron • Transmission of the neural impulse along the neuron
  • 3. NERVOUS SYSTEM Central Nervous Peripheral Nervous System (CNS) System (PNS) Spinal Somatic System Autonomic Nervous BRAIN Cord (Motor & Sensory) System (ANS) Voluntary Sympathetic Parasympathetic
  • 4.
  • 8.
  • 9. The Neuron • Resting Potential • Threshold • Action Potential • ‘All or none’ law
  • 10. The Neuron • Sodium ions (Na+) • Potassium ions (K+) • Chloride ions (CL-) • (Also, Protein ions An-)
  • 11. Resting Potential Axon - - - - - - - - - - - - -
  • 12. Distribution of Negative Ions Axon CL- CL- CL- CL- An- CL- An- An- An- An- CL- CL- CL- CL- CL- An- Trapped inside axon CL- greater concentration outside axon than inside
  • 13. Distribution of Positive Ions Axon Na+ Na+ Na+ Na+ K+ Na+ K+ K+ K+ K+ K+ Na+ K+ K+ Na+ Na+ K+ Na+ Na+ K+ greater concentration inside axon than outside Na+ greater concentration outside axon than inside
  • 14. Resting Potential The resting potential is maintained by: 1. Selectively Permeable Membrane 2. Sodium – Potassium Pump
  • 15. Resting Potential Axon Na+ Na+ Na+ Na+ K+ Na+ K+ K+ K+ K+ K+ Na+ K+ K+ Na+ Na+ K+ Na+ Na+ 3 Sodium ions (Na+) pumped out for every 2 Potassium ions (K+) drawn in
  • 16. Propagation Propagation of the action potential refers to the transmission of the action potential along the axon.
  • 17. Propagation Axon + +++ - - - - - +++ - - - - - - +
  • 18. Propagation Axon - - +++ - - - - - - - +++ - - -
  • 19. Propagation Axon - - - - - +++ - - - - - - +++
  • 20. Saltatory Conduction Saltatory conduction is the transmission of the impulse from node to node
  • 21.
  • 22. "All or None" law If the threshold is reached the neuron will 'fire' (ie a neural impulse will occur) if it is not reached the neuron will not fire • Therefore, the size and shape of the action potential are independent of the intensity of the stimulus that initiated it
  • 23. Refractory Period For a few milliseconds following a neural impulse the membrane is temporarily unexcitable and the axon cannot be fired again regardless of the strength of the stimulus. This interval is known as the Absolute Refractory period
  • 24. Refractory Period Following the Absolute Refractory period • there is a short period of time just before the membrane returns to normal during which the neuron will fire but a stronger than normal stimulus is required • This period of time is called the Relative Refractory period
  • 25. Neuron Plasticity & Age The structure of the neuron is fairly ‘plastic’, that is the fibres of the neuron can increase or decrease their branching pattern as a function of age, experience and chemical influences.
  • 27. Glia (Neuroglia) • Glia are the other main component of the nervous system besides neurons • Occupy about the same total space as neurons • They do not transmit information
  • 28. Glia Functions • Remove waste • Fill space left by dead neurons (form scar tissue) • Build the myelin sheath - Schwann cells (PNS) - Oligodendrocytes (CNS)
  • 29. Spinal Research Raisman (1997) • Olfactory cells from the nose (although CNS cells) can regenerate and form functional connections after damage
  • 30. Spinal Research Raisman (1997) • Studies using Schwann sheath, found although they provide guidance to a regenerating spinal cord, the cord can not make the connection at the other end into the oligodendrocyte • Olfactory cells were able to make that connection.
  • 31.
  • 32. EEG Electroencephalograph (EEG) Machine that records the electrical activity of the brain via electrodes placed on the surface of the scalp Electroencephalogram (EEG) Trace or record of the electrical activity of the brain
  • 33.
  • 35. References Carlson, N. (2010). Physiology of Behavior, (10th ed). London: Allyn & Bacon. Kalat, J. (2009). Biological Psychology, (10th ed). Belmont, California: Wadsworth. Pinel, J.P. (2008). Biopsychology, (7th ed). London: Allyn & Bacon.