We are the Students from the University of Rizal System-Rodriguez Rizal. This power point presentation aims to help the other students to find more reliable sources like ours when it comes to Mythology and Folklore. Special thanks to the group members and to Dr. Stephen P. Soliguen. To God be the Glory!
Prof. OP Budholia and Dr Naveen K Mehta's Compilation of the Study Stuff in the larger benefit and interest of student community .
Greatly acknowledge all the sources......
We are the Students from the University of Rizal System-Rodriguez Rizal. This power point presentation aims to help the other students to find more reliable sources like ours when it comes to Mythology and Folklore. Special thanks to the group members and to Dr. Stephen P. Soliguen. To God be the Glory!
Prof. OP Budholia and Dr Naveen K Mehta's Compilation of the Study Stuff in the larger benefit and interest of student community .
Greatly acknowledge all the sources......
Sophocles wrote more than 120 plays, but only seven complete tragedies survive. Of the rest, only some titles and fragments remain. Sophocles’ repute as a playwright rests on the seven surviving plays: Ajax, Antigone, Electra, Oedipus the King, The Trachinae, Philoctetes, and Oedipus at Colonus. Oedipus Rex generally regarded as Sophocles’ masterpiece, presents the myth of Oedipus, the man fated to kill his father and marry his mother.
Otus and Ephialtes are one of the stories of the four great adventures. Otus and Ephialtes were Poseidon's twin Giant brothers. They were massive and ambitious, and they had to show that they were better than the gods.
Jason and the Argonauts, who sailed in search of the Golden Fleece is one of the most famous stories in Greek Mythology. The story is made into movie and TV series several times.
Sophocles wrote more than 120 plays, but only seven complete tragedies survive. Of the rest, only some titles and fragments remain. Sophocles’ repute as a playwright rests on the seven surviving plays: Ajax, Antigone, Electra, Oedipus the King, The Trachinae, Philoctetes, and Oedipus at Colonus. Oedipus Rex generally regarded as Sophocles’ masterpiece, presents the myth of Oedipus, the man fated to kill his father and marry his mother.
Otus and Ephialtes are one of the stories of the four great adventures. Otus and Ephialtes were Poseidon's twin Giant brothers. They were massive and ambitious, and they had to show that they were better than the gods.
Jason and the Argonauts, who sailed in search of the Golden Fleece is one of the most famous stories in Greek Mythology. The story is made into movie and TV series several times.
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Top 10 Best Ayurvedic Kidney Stone Syrups in India
MYTHPOP A53 Final Project
1. A MYTHPOP A53 Final Requirement by Franco “Ren” Morales
2. LEGEND OF PERSEUS
Perseus was born to
Danae, the daughter of
king Apollo, and the
almighty Zeus after his
mother was locked in a
tower by her father after an
oracle prophesized that her
son will kill him.
3. RISE OF THE GUARDIANS
Jack Frost ‘awakens’, having
no memory of who he is,
and finds himself to be
literally a ghost among the
people. Dejected, he then
sets off alone…
4. LEGEND OF PERSEUS
After being cast away with
his mother to the sea by
Apollo, the pair ended up
on the island of Seriphos,
ruled by Polydectes. There,
they were saved by the
fisherman, Dictys, and they
soon lived a normal life for
many years…
5. RISE OF THE GUARDIANS
As the centuries go by and the
modern era arrives, Jack Frost
becomes known (at least to himself
and other magical beings) as a
mischievous spirit, using his powers
over ice and frost to cause mischief,
but never fails to leave a trail of fun
in his wake. However, he is dejected
when he is the one magical being in
the world who no one believes in.
6. LEGEND OF PERSEUS
When Perseus was a young
man, he protected his
mother from being
forcefully married by
Polydectes. As a result, the
king devised a plan to get
rid of Perseus—have him
bring back the head of
Medusa, which he was sure
he would fail to do.
7. RISE OF THE GUARDIANS
The Guardians—North/Santa
Claus, Tooth Fairy,
Bunnymund/Easter Bunny,
and Sandy/Sandman, call
upon Jack to join them
because he was chosen by the
‘Man in the Moon’, an
omnipotent spirit responsible
for choosing Guardians to
protect the imagination and
beliefs of children around the
world.
9. RISE OF THE GUARDIANS
However, Jack refuses to join
the Guardians, but is
persuaded into doing so when
the appearance of Pitch
Black/Boogeyman threatens
their very existence and the
beliefs of all children in the
world.
10. LEGEND OF PERSEUS
While on his way to slay
Medusa, Hermes and Athena
appeared before Perseus to
give him three things—a pair
winged sandals, a sickle, and
a shield to aid him against
Medusa. Later on, the
Nymphs of the North gave
him a cap to turn himself
invisible, and a magic wallet.
11. RISE OF THE GUARDIANS
To aid in his spread of
mischief and the ‘Jack Frost
kind of fun’, Jack uses a
wooden staff he has been
in possession of ever since
he was ‘born’.
12. LEGEND OF PERSEUS
While on his way to the lair
of the Gorgons, Perseus
suddenly fell into a bout of
hopelessness when he
realized how dangerous
they were, only for the
appearance of Hermes and
Athena to prevent his heart
from giving into the fear.
13. RISE OF THE GUARDIANS
With children around the
world losing faith in the
Tooth Fairy, and being
subjected to nightmares
now that Sandy is ‘dead’,
Jack and the remaining
Guardians try to help
Bunnymund in preparing
for Easter to keep Pitch
Black from succeeding in
his mission.
14. LEGEND OF PERSEUS
After being instructed by
Hermes and Athena on
where to go and what to
do, Perseus went to the lair
of the Graeae, stealing
their single eye and
demanding the location of
the Nymph of the North in
order to be given items
that will help him defeat
Medusa.
15. RISE OF THE GUARDIANS
After failing to defend Tooth Fairy’s
lair and helpers, except for one,
from being kidnapped by Pitch
Black, Jack soon learns that he could
regain his human memories if he
helps the Guardians collect
children’s teeth from the around the
world, which he willingly accepts.
16. LEGEND OF PERSEUS
Reaching his destination,
Perseus managed to
behead Medusa and put
her severed head into his
magic wallet, narrowly
escaping the wrath of her
Gorgon sister in the
process.
17. RISE OF THE GUARDIANS
When fighting against
Pitch Black for the second
time that results in Sandy’s
‘death’, Jack finds out that
his powers over ice are
more potent than he
thought of them to be,
being channeled through
the very wooden staff that
he has used ever since he
was ‘born’.
18. LEGEND OF PERSEUS
Perseus never encountered
a ‘temptress’ or anything
like that to distract him
from his journey of
returning home to
Seriphos, although he did
stop to save Andromeda
from a sea monster, and
before marrying her later
on.
19. RISE OF THE GUARDIANS
Having no memory of his past
life, Jack is distracted by Pitch
Black with a container
containing his baby tooth, which
also carries his memories when
he was still a human.
Unfortunately, this distraction
proves disastrous as Jack fails to
save Bunnymund’s lair from
being attacked, thus, the spirit of
Easter vanishes from children. As
a result of being blamed for
failing to protect them, Jack
leaves and goes on a selfimposed exile.
20. LEGEND OF PERSEUS
While having never met his father before, from the
encounter with Hermes and Athena, Perseus learns that he is
the son of Zeus, which is enough to merit him their support
in his quest.
21. RISE OF THE GUARDIANS
After making a deal with Pitch Black
that results in his staff being broken,
he manages to regain his baby tooth
and find out his origins– that of a
regular teenage boy who died while
saving his little sister from falling
into an ice pond, only for his
sacrifice to have the Man in the
Moon turn him into who he is now—
Jack Frost. Overjoyed that he finally
regained his memories, Jack repairs
his staff through sheer will and sets
off to rejoin the Guardians.
22. LEGEND OF PERSEUS
Having returned to
Seriphos, Perseus finds out
from Dictys that his while
he was away, Polydectes
forced his mother to
become his servant. This
would lead to Perseus
confronting the king and
turning him to stone with
Medusa’s severed head.
23. RISE OF THE GUARDIANS
Trying to prevent Pitch Black from
achieving his goals by helping a boy,
Jamie, whom Jack firmly believed earlier
could believe in him and successfully
does, Jack, the Guardians, Jamie and his
friends confront Pitch Black, resulting in
a revival of the children’s faith that
resurrects Sandy, allowing the Guardians
to finally defeat Pitch Black for good.
24. LEGEND OF PERSEUS
With Polydectes gone and his mother set free, Perseus was
finally able to return to his normal life, but now with
Andromeda by his side as his loyal wife.
25. RISE OF THE GUARDIANS
Having helped defeat and
drive back Pitch Black to
where he came from, Jack
finally accepts his place as
a member of the
Guardians, and sets off
with them to continue
protecting the world of
children’s imaginations and
beliefs.