Molly And Her New Friend
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Molly was an outsider in her class because she had pale hair and pale eyes, unlike her dark-haired classmates. She was often mocked and excluded from playing. A new student named Milly then joins the class, and he also has pale hair and pale eyes. Molly offers Milly a piece of candy, and they become friends. From then on, Molly and Milly have each other for support and go on adventures together.
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Molly And Her New Friend
Molly is an odd girl who has pale hair and eyes, so the other children don't want to play with her. One day, a new student named Milly joins the class. Milly also has pale hair and eyes, so the other children reject him as well. However, Molly offers Milly a piece of candy and invites him to play, beginning a friendship between the two outsiders.
The Foxglove Legacy - Chapter 5
This chapter follows the daily lives and development of Holly Blue Foxglove and her sisters Madeline and Lauren. Key events include:
1) Holly Blue enjoys school and making new friends but still considers her best friend to be Orlando Bertino.
2) Madeline discovers the toilet but is told she can no longer play in it due to her upcoming birthday.
3) Dominic tells Madeline that Evangeline is not actually her mother and that she was conceived when he was abducted by aliens, though Evangeline still loves her.
4) Holly Blue and Madeline reaffirm their strong friendship despite this revelation about Madeline's origins.
The Foxglove Legacy - Chapter 4
This chapter summarizes the events in the Foxglove family. Evangeline gives birth to a daughter named Lauren who has unusually pale skin. Holly Blue starts school and proves to be well-behaved despite not getting great grades. Madeline is taught to walk and talk by her father Dominic. Lauren grows into a toddler who resembles her mother but has pale skin like her sister Lauren.
Playground script
Scarlet, a troubled teenager, is seen sitting alone in an empty school playground with bruises on her face. In her next class, Scarlet is well-dressed and joking with friends but not paying attention to the teacher's lecture about drugs. When called on, Scarlet cheekily accuses the teacher, Mr. Philips, of taking drugs behind the school. Though this should provoke a serious response, Mr. Philips simply gives Scarlet detention with a wink. The film title "Playground" is then shown, hinting at a dark storyline involving Scarlet and her teacher.
Dulcibella Legacy-G9 c1
Micah and his new wife Shelly celebrate their marriage at the Dulcibella house, avoiding conflict with Micah's father Almeric. Shelly reveals her real name is Michelle. They have a baby on the way for Generation 10 of the Dulcibella legacy. Regalia bonds with Shelly over music. Despite Almeric's disapproval, Micah and Shelly remain happily married. Shelly gives birth to a red-headed boy, completing the ten generation legacy.
Script final unit22 edited one
Michael gets into a fight at a friend's party and storms off, walking home alone at night despite warnings. On his walk, he encounters a homeless man who asks for change. Michael verbally abuses the man and continues on, becoming more angry and unstable. He sees a shadow that morphs into a demonic figure, which chases him and drags him into the ground, ending in a scream.
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Michael gets drunk at a friend's party and gets into a fight. His friends try to calm him down but he insists on leaving alone. While walking through the park upset, Michael encounters a homeless man who asks for change. Michael rudely tells the man to get a job and mocks him. Further along his walk, Michael sees a shadow taking the shape of his deceased grandfather then transforming into a large, horned figure. The figure reveals itself to be the homeless man, who laughs evilly as Michael screams in terror before the man drags Michael into the ground.
Teddysw swimming race
This story is about three teddy bear friends named Emily, Molly, and Emma who receive a mysterious letter inviting them to a swimming race. Emily checks that she has all her gear for the race, but when she arrives at the competition, she realizes her goggles are missing. She accuses Sugar, a mean girl teddy bear, of stealing her goggles. It is then announced that the swimming race has been cancelled.
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Molly And Her New Friend
Molly is an odd girl who has pale hair and eyes, so the other children don't want to play with her. One day, a new student named Milly joins the class. Milly also has pale hair and eyes, so the other children reject him as well. However, Molly offers Milly a piece of candy and invites him to play, beginning a friendship between the two outsiders.
The Foxglove Legacy - Chapter 5
This chapter follows the daily lives and development of Holly Blue Foxglove and her sisters Madeline and Lauren. Key events include:
1) Holly Blue enjoys school and making new friends but still considers her best friend to be Orlando Bertino.
2) Madeline discovers the toilet but is told she can no longer play in it due to her upcoming birthday.
3) Dominic tells Madeline that Evangeline is not actually her mother and that she was conceived when he was abducted by aliens, though Evangeline still loves her.
4) Holly Blue and Madeline reaffirm their strong friendship despite this revelation about Madeline's origins.
The Foxglove Legacy - Chapter 4
This chapter summarizes the events in the Foxglove family. Evangeline gives birth to a daughter named Lauren who has unusually pale skin. Holly Blue starts school and proves to be well-behaved despite not getting great grades. Madeline is taught to walk and talk by her father Dominic. Lauren grows into a toddler who resembles her mother but has pale skin like her sister Lauren.
Playground script
Scarlet, a troubled teenager, is seen sitting alone in an empty school playground with bruises on her face. In her next class, Scarlet is well-dressed and joking with friends but not paying attention to the teacher's lecture about drugs. When called on, Scarlet cheekily accuses the teacher, Mr. Philips, of taking drugs behind the school. Though this should provoke a serious response, Mr. Philips simply gives Scarlet detention with a wink. The film title "Playground" is then shown, hinting at a dark storyline involving Scarlet and her teacher.
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Micah and his new wife Shelly celebrate their marriage at the Dulcibella house, avoiding conflict with Micah's father Almeric. Shelly reveals her real name is Michelle. They have a baby on the way for Generation 10 of the Dulcibella legacy. Regalia bonds with Shelly over music. Despite Almeric's disapproval, Micah and Shelly remain happily married. Shelly gives birth to a red-headed boy, completing the ten generation legacy.
Script final unit22 edited one
Michael gets into a fight at a friend's party and storms off, walking home alone at night despite warnings. On his walk, he encounters a homeless man who asks for change. Michael verbally abuses the man and continues on, becoming more angry and unstable. He sees a shadow that morphs into a demonic figure, which chases him and drags him into the ground, ending in a scream.
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Michael gets drunk at a friend's party and gets into a fight. His friends try to calm him down but he insists on leaving alone. While walking through the park upset, Michael encounters a homeless man who asks for change. Michael rudely tells the man to get a job and mocks him. Further along his walk, Michael sees a shadow taking the shape of his deceased grandfather then transforming into a large, horned figure. The figure reveals itself to be the homeless man, who laughs evilly as Michael screams in terror before the man drags Michael into the ground.
Teddysw swimming race
This story is about three teddy bear friends named Emily, Molly, and Emma who receive a mysterious letter inviting them to a swimming race. Emily checks that she has all her gear for the race, but when she arrives at the competition, she realizes her goggles are missing. She accuses Sugar, a mean girl teddy bear, of stealing her goggles. It is then announced that the swimming race has been cancelled.
Body idioms
This document provides a summary of idioms related to parts of the body in English. It includes idioms using common body parts like leg, ears, tooth, eye, lips, hand, neck, skin, hair, nose, shoulder, stomach and mouth. Short explanations and examples are provided for each idiom. The document was created by Tatiana Grigorievna Piskunova, an English teacher at Gymnasium No. 15 named after N.N. Belousov using the "Spotlight" textbook for 10th grade.
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Marcy wakes up late for school and rushes to get ready. She jumps in the minivan with her family and they drive to school, where Marcy meets up with her best friend Demi. They discuss an upcoming math test they are nervous about. In history class, their teacher Mr. Holland discusses the early history of North America, focusing on Jamestown as the first permanent English colony, though acknowledging that others like Native Americans and Spanish explorers came before. The students complain they want a more exciting topic like the Civil War, but Mr. Holland insists they will be learning about American history.
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The document is a collection of short passages written by students about why their mothers are special or why they love their mothers. Many of the students say their mothers are special because they give hugs, kisses and cuddles. Other reasons mentioned include mothers baking together, going to the park, helping with cooking, and looking after their children. Overall, the students express love and appreciation for the caring relationships they have with their mothers.
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I have some plans for Halloween this year. First, I will accompany my cousin trick-or-treating because I enjoy seeing children participate in this Halloween tradition. If I have time afterwards, I may attend a costume party to dance, compete in contests, and have fun, as costume parties are one of the reasons I enjoy Halloween. Another option is to go trick-or-treating or disguising myself, but I think I am too old for that now. I could also try to scare children with my friends while in disguise, but that may be difficult since children are not easily frightened these days.
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A teenager named Scarlet is seen alone in an empty school playground with bruises and blood on her pale face. She looks troubled and in danger. In a classroom, Scarlet sits next to her teacher Mr. Philips. The two exchange a long stare with tension between them while the other students look confused. The school bell rings and Scarlet hesitates before leaving the classroom as the scene fades to black, implying something suspicious between Scarlet and her teacher.
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Willy gets in an argument with his friend Tom at a concert after making insensitive comments about a boy's swimwear. Willy runs away in a panic and gets lost in a poor neighborhood. Exhausted and without his phone, Willy meets a kind woman who offers him shelter and listens to his story. She offers to help Willy contact his friend to make amends.
Bholi english ncert syllabus class 11 presentation
Here are two possible responses to the question:
1. The story presents the social attitudes of the time that girls' value was tied to their beauty and ability to get married. People with disabilities faced neglect and ridicule. Bholi's teacher helped her overcome these barriers through kindness, encouragement and belief in her potential. She told Bholi that with regular school attendance and practice, she could overcome her stammer. The teacher gave Bholi confidence and hope for a better future where she could read, speak well and gain respect - showing that one caring person can make a significant difference in someone's life.
2. You're right that while God created the world, teachers play a crucial role in shaping human beings. B
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Molly Burke is a blind activist who has faced adversity from a young age. She was diagnosed with retinitis pigmentosa at age 4, which caused her vision to deteriorate until she became fully blind at age 14. In school, Molly experienced bullying from her peers for her blindness. She now shares her story of overcoming bullying through public speaking at events around the world to inspire others. After high school, Molly became involved with organizations like Free The Children and Me to We through her brother, finding her passion in helping others.
Maddie's P3 Project
Molly Burke is a blind activist who was diagnosed with retinitis pigmentosa at age 4, causing her vision to deteriorate until she became fully blind at age 14. She began public speaking at age 5 about her experiences with bullying and going blind. Though bullied in high school, she graduated and became involved with organizations like Free The Children and Me to We, going on trips to help others. She inspires many with her optimism and story of overcoming bullying and vision loss.
Dance Till Your Dreams Come True!!!
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Emily is excited to take the lead role of Rose the fairy in her ballet show after her friend Lauren injures her ankle. However, Emily starts to feel nervous that she will not be able to learn all the dance steps in just one day. On the day of the show, Emily is scared she will forget the steps and mess up the performance. However, with the support of her mother and ballet teacher, Emily successfully performs the dance and receives a standing ovation from the audience.
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Emily is excited to take the lead role of Rose the fairy in her ballet show after her friend Lauren injures her ankle. However, Emily has doubts about being able to learn the dance steps in just one day. On the day of the show, Emily is nervous but her mother reassures her. When Emily sees her beautiful costume and arrives at the theater, she gains confidence. Emily performs the dance perfectly on stage to the applause of the audience, realizing her dream of being the lead role.
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This story is about three teddy bear friends named Emily, Molly, and Emma who receive a mysterious letter inviting them to a swimming race. Emily checks that she has all her gear for the race, but when she arrives at the competition, she realizes her goggles are missing. She accuses Sugar, a mean girl teddy bear, of stealing her goggles. It is then announced that the swimming race has been cancelled.
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The document is a screenplay that depicts tender phone conversations between a mother, Molly, and her children while she is in prison. It shows Molly's release from prison and her struggles to secure housing and reunite with her children, who are in foster care. She lies to various people about her living and work situations due to shame and embarrassment over having been in prison. She has an emotional reunion with her old friend Amina at the council office.
LOLLIPOP (POSY STERLING).pdf
The document is a screenplay that depicts tender phone conversations between a mother, Molly, and her children while she is in prison. It shows Molly's release from prison and her struggles to secure housing and reunite with her children, who are in foster care. She lies to various people about her living and work situations due to shame and embarrassment over having been in prison. She has an emotional reunion with her old friend Amina at the council office.
Molly and the three bears
1) Molly gets transported into the story of Goldilocks and the Three Bears while her mother reads it to her.
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3) When the bears return home, Molly hides under the bed but is found and thanked by the bears for her improvements.
4) Molly realizes she must wait for the story to end to return home, and does so while waving goodbye to her new bear friends.
Discrimination
The document describes a story about twins John and Ellen and their normal school day. It provides details about their different activities throughout the day from waking up to doing homework. The story aims to show how stereotypes may lead one to incorrectly assume that because they are twins, John and Ellen must do all the same things, when in reality they have different interests and behaviors.
I am malala
This document provides background on Malala Yousafzai's early life in three paragraphs. She was born in Mingora, Pakistan to Ziauddin and Peshon Yousafzai. Though most Pashtuns see the birth of a daughter as unfortunate, her father celebrated her birth and saw her as special. She was named after Malalai of Maiwand, a famous Afghan folk heroine who inspired her people to defeat the British in battle. The document provides context on Pashtun culture and values like hospitality, honor, and fighting to defend their lands from outsiders.
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Body idioms
This document provides a summary of idioms related to parts of the body in English. It includes idioms using common body parts like leg, ears, tooth, eye, lips, hand, neck, skin, hair, nose, shoulder, stomach and mouth. Short explanations and examples are provided for each idiom. The document was created by Tatiana Grigorievna Piskunova, an English teacher at Gymnasium No. 15 named after N.N. Belousov using the "Spotlight" textbook for 10th grade.
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Marcy wakes up late for school and rushes to get ready. She jumps in the minivan with her family and they drive to school, where Marcy meets up with her best friend Demi. They discuss an upcoming math test they are nervous about. In history class, their teacher Mr. Holland discusses the early history of North America, focusing on Jamestown as the first permanent English colony, though acknowledging that others like Native Americans and Spanish explorers came before. The students complain they want a more exciting topic like the Civil War, but Mr. Holland insists they will be learning about American history.
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The document contains summaries of two fairy tales: Snow White and Cinderella. For Snow White, it describes how she fled into the woods after her aunt and uncle wanted to leave her behind, found shelter in a cottage belonging to seven dwarfs, and eventually came to live with them happily. For Cinderella, it tells how her fairy godmother helped her attend the king's ball, where she danced with and fell in love with the prince, and ultimately married him after her glass slipper revealed her identity. Both stories follow the common narrative structure of orientation, complication, and resolution.
Snow Fun At Marlcliffe
The sixth grade class at Marlcliffe School had a snow graffiti lesson outside while the rest of the school had an indoor writing competition, with the prize being time to play in the snow and throw snowballs at their teacher, Mr. Brooks. Students created snow angels and had snowball fights, with one student, Laurence, writing a poem about enjoying the sight of nighttime snowball fights from his bedroom window before having to go back to sleep.
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The document is a collection of short passages written by students about why their mothers are special or why they love their mothers. Many of the students say their mothers are special because they give hugs, kisses and cuddles. Other reasons mentioned include mothers baking together, going to the park, helping with cooking, and looking after their children. Overall, the students express love and appreciation for the caring relationships they have with their mothers.
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I have some plans for Halloween this year. First, I will accompany my cousin trick-or-treating because I enjoy seeing children participate in this Halloween tradition. If I have time afterwards, I may attend a costume party to dance, compete in contests, and have fun, as costume parties are one of the reasons I enjoy Halloween. Another option is to go trick-or-treating or disguising myself, but I think I am too old for that now. I could also try to scare children with my friends while in disguise, but that may be difficult since children are not easily frightened these days.
Playground final script
A teenager named Scarlet is seen alone in an empty school playground with bruises and blood on her pale face. She looks troubled and in danger. In a classroom, Scarlet sits next to her teacher Mr. Philips. The two exchange a long stare with tension between them while the other students look confused. The school bell rings and Scarlet hesitates before leaving the classroom as the scene fades to black, implying something suspicious between Scarlet and her teacher.
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A DAY IN THE LIFE OF THE FAMOUS INTERACTIVE GRAPHIC DESIGNER ALEJANDRO NICOLAS
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Willy gets in an argument with his friend Tom at a concert after making insensitive comments about a boy's swimwear. Willy runs away in a panic and gets lost in a poor neighborhood. Exhausted and without his phone, Willy meets a kind woman who offers him shelter and listens to his story. She offers to help Willy contact his friend to make amends.
Bholi english ncert syllabus class 11 presentation
Here are two possible responses to the question:
1. The story presents the social attitudes of the time that girls' value was tied to their beauty and ability to get married. People with disabilities faced neglect and ridicule. Bholi's teacher helped her overcome these barriers through kindness, encouragement and belief in her potential. She told Bholi that with regular school attendance and practice, she could overcome her stammer. The teacher gave Bholi confidence and hope for a better future where she could read, speak well and gain respect - showing that one caring person can make a significant difference in someone's life.
2. You're right that while God created the world, teachers play a crucial role in shaping human beings. B
Maddie's P3 Project
Molly Burke is a blind activist who has faced adversity from a young age. She was diagnosed with retinitis pigmentosa at age 4, which caused her vision to deteriorate until she became fully blind at age 14. In school, Molly experienced bullying from her peers for her blindness. She now shares her story of overcoming bullying through public speaking at events around the world to inspire others. After high school, Molly became involved with organizations like Free The Children and Me to We through her brother, finding her passion in helping others.
Maddie's P3 Project
Molly Burke is a blind activist who was diagnosed with retinitis pigmentosa at age 4, causing her vision to deteriorate until she became fully blind at age 14. She began public speaking at age 5 about her experiences with bullying and going blind. Though bullied in high school, she graduated and became involved with organizations like Free The Children and Me to We, going on trips to help others. She inspires many with her optimism and story of overcoming bullying and vision loss.
Dance Till Your Dreams Come True!!!
Emily is excited to take the lead role of Rose in her ballet show after her friend Lauren injures her ankle. Emily has only been taking ballet for a year but works hard to learn the steps. On the day of the show she is very nervous about performing alone but her mother reassures her. Emily shines in the performance and receives a standing ovation, realizing she was capable of more than she thought.
Eee
Emily is excited to take the lead role of Rose the fairy in her ballet show after her friend Lauren injures her ankle. However, Emily starts to feel nervous that she will not be able to learn all the dance steps in just one day. On the day of the show, Emily is scared she will forget the steps and mess up the performance. However, with the support of her mother and ballet teacher, Emily successfully performs the dance and receives a standing ovation from the audience.
Eee
Emily is excited to take the lead role of Rose the fairy in her ballet show after her friend Lauren injures her ankle. However, Emily has doubts about being able to learn the dance steps in just one day. On the day of the show, Emily is nervous but her mother reassures her. When Emily sees her beautiful costume and arrives at the theater, she gains confidence. Emily performs the dance perfectly on stage to the applause of the audience, realizing her dream of being the lead role.
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The third in a series of comics about Penny, a girl raised by penguins. Check out the full site at: www.pennythepenguingirl.com
Teddysw swimming race
This story is about three teddy bear friends named Emily, Molly, and Emma who receive a mysterious letter inviting them to a swimming race. Emily checks that she has all her gear for the race, but when she arrives at the competition, she realizes her goggles are missing. She accuses Sugar, a mean girl teddy bear, of stealing her goggles. It is then announced that the swimming race has been cancelled.
LOLLIPOP (POSY STERLING).pdf
The document is a screenplay that depicts tender phone conversations between a mother, Molly, and her children while she is in prison. It shows Molly's release from prison and her struggles to secure housing and reunite with her children, who are in foster care. She lies to various people about her living and work situations due to shame and embarrassment over having been in prison. She has an emotional reunion with her old friend Amina at the council office.
LOLLIPOP (POSY STERLING).pdf
The document is a screenplay that depicts tender phone conversations between a mother, Molly, and her children while she is in prison. It shows Molly's release from prison and her struggles to secure housing and reunite with her children, who are in foster care. She lies to various people about her living and work situations due to shame and embarrassment over having been in prison. She has an emotional reunion with her old friend Amina at the council office.
Molly and the three bears
1) Molly gets transported into the story of Goldilocks and the Three Bears while her mother reads it to her.
2) Inside the story, Molly improves the bears' house by making sandwiches instead of porridge and decorating their bare bedroom.
3) When the bears return home, Molly hides under the bed but is found and thanked by the bears for her improvements.
4) Molly realizes she must wait for the story to end to return home, and does so while waving goodbye to her new bear friends.
Discrimination
The document describes a story about twins John and Ellen and their normal school day. It provides details about their different activities throughout the day from waking up to doing homework. The story aims to show how stereotypes may lead one to incorrectly assume that because they are twins, John and Ellen must do all the same things, when in reality they have different interests and behaviors.
I am malala
This document provides background on Malala Yousafzai's early life in three paragraphs. She was born in Mingora, Pakistan to Ziauddin and Peshon Yousafzai. Though most Pashtuns see the birth of a daughter as unfortunate, her father celebrated her birth and saw her as special. She was named after Malalai of Maiwand, a famous Afghan folk heroine who inspired her people to defeat the British in battle. The document provides context on Pashtun culture and values like hospitality, honor, and fighting to defend their lands from outsiders.
presentation "Hidden Danger"
The scenario introduces Kim, a shy nerdy girl in college, and three popular cool girls who bully her. In scene 1, one of the cool girls drops a piece of paper on Kim during class as everyone laughs. In scene 2, another cool girl spills coffee on Kim in the cafeteria. In scene 3, two cool girls push Kim in the hallway, causing her to drop her books. In scene 4, the three cool girls confront Kim after school, punching her and causing her to fall down. When Kim looks up angrily, her eyes turn red and she grows teeth before there is a scream and darkness. In scene 5, Kim is seen confidently walking through the school with her hair down and
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This document discusses different types of bullying and its effects. It defines bullying as intentional, repeated harm against someone through verbal, physical, or online means. Cyberbullying is discussed as being able to occur anywhere at any time. The story of Amanda Todd, who committed suicide after being bullied both in school and online, is presented. The document also shares a first-hand account of someone who was bullied throughout middle school and developed depression and started self-harming as a result. It provides information on ways to get help, such as talking to friends, family or teachers or filling out complaint forms at school.
Pregnancy six
Flora gave birth to twins Ginger and Geranium. Her oldest children Chamomile, Borage, and Dill worked hard to save money for college by fixing up cars. They were able to sell the cars and earn enough for college. Flora was proud to see her eldest children leave for their first semester at a dorm. Meanwhile, Euca earned money through dating and found pirate treasure, which she shared with her siblings. On the twins' birthday, Flora threw a party and said goodbye to the oldest kids as they left for college. Shortly after, Flora gave birth to another daughter named Heather.
Jamaican children right summative assesment
1) The narrator, Olivier, moved from Jamaica to the US for school but faced racism and bullying from his classmates and teachers.
2) With the help of his friend James, Olivier joined the NAAP organization to fight against unfair treatment and convince others that racism should not be tolerated.
3) Through their efforts, the NAAP organization was able to successfully spread the message of equality and fairness for all people and end racism in the schools and community.
Jamaican children right's
1) The narrator, Olivier, moved from Jamaica to the US for school but faced racism and bullying from his classmates and teachers due to his race.
2) With the help of his friend James, Olivier joined the NAAP organization to fight against unfair treatment and convince others that racism should not be tolerated.
3) Through their efforts, the NAAP organization was able to successfully spread an anti-racism message around the school and world, resulting in Olivier's bullies apologizing and everyone learning to treat each other fairly.
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Bholi english ncert syllabus class 11 presentation
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Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
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How to Control Your Asthma Tips by gokuldas hospital.
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- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
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Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
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1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
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Molly And Her New Friend
- 1. By: Rebecca Holman Someone Like Molly
- 2. Molly lived in a black and white world. Her biggest thrill was to run down sidewalks and play in mud puddles. Sadly, Molly did not have many friends to play with since she had pale hair and pale eyes. Everyone else has dark hair and dark eyes.
- 3. Molly ran down the sidewalk as fast as she could to lunch. “Stop running this instant Molly!” Mrs. Yelnan yelled at her.
- 4. Molly stopped and waited for the teacher to catch up. “Really, Molly, what an odd girl you are. No more running after that butterfly. Now, you best get back in line.” Molly nodded her head and went back to the empty spot in front of the curly haired girl.
- 5. The curly-haired girl behind her mocked, ”You are so hideous, Molly, with your pale eyes and pale hair.” Molly didn’t say anything in return to the nasty comment.
- 6. The bell rang. “Yippee, school is out!” she cheered when she opened the door. Molly ran home excitedly, so she could see her mother.
- 7. Molly told her mom and dad all about her day and asked if she could go out and play. “Yes, but only for a little while,” her mom said while making dinner.
- 8. The neighbor kids were jumping rope, so Molly made her way over to ask if she could jump too. “May I jump with you?” Molly asked as politely as she could. “No you can’t. You are so hideous, Molly, with your pale eyes and pale hair. You are not welcome here,” the boy skipping rope replied.
- 9. Molly walked away from the laughing children and went home.
- 10. The next day at school, Mrs. Yelnan announced that there was a new student from Blauren, a neighboring town, joining the class. The boy boldly stood in front of the class.
- 11. His pale eyes and pale hair made everyone grimace and look at Molly, but they all yelled, “Welcome!” Brrrrrrng! Everyone jumped out of their seats for recess.
- 12. Molly walked outside and found the boy sitting alone on the swings. Nobody had even invited him to play in the sandbox with all of the other boys. Molly timidly offered the boy a piece of candy that she was going to devour later after school.
- 13. The boy looked up at her. " My name is Milly. What is yours?” he asked. Molly told Milly his name while he ate the piece of candy. “Would you like to play on the slide with me?” Molly asked. “Sure!” Milly jumped up excitedly and made for the slide.
- 14. From then on Molly and Milly were the best of friends and had many wacky adventures. They made friends with new people along the way, but that is another story.