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MIGRAINE - A HEADACHE FOR
PAEDIATRICIAN
Dr. Muzammil Koshish
MBBS DCH DNB(PAEDIATRICS)
z
Headache classification
• Primary headache
migraine, tension , cluster
• Secondary headache
Infection, trauma, hemorrhage, tumor, high
intracranial pressure.
• Cranial neuropathies
z
Migraine
• Episodic, periodic, paroxysmal attacks of modera
te to severe throbbing pain, separated by pain
free intervals,
• Associated with nausea, vomiting, photophobia,
abdominal pain and desire to sleep, motion sickn
ess.
• Family history 70-90%
z
Classification of migraine
(revised international headache society IHS 2004)
• Migraine without aura
• Migraine with aura
z
Migraine without aura (IHS 2004)
• A. at least 5 attacks fulfilling criteria B through D.
• B. Headache attacks lasting 4 to 72h
• C. headache has at least 2 of the following
-unilateral location
-pulsating quality
-moderate or severe pain intensity
-aggravation by or causing avoidence of
routine physical activity
• D. during headache at least one of the folowing:
nausea, vomiting, or both, photophobia, phonophobia
• E. not attributed to another disorder.
z
Migraine with aura (IHS 2004)
• A. at least 2 attacks fulfilling criteria B.
• B. migraine aura fulfilling criteria B or C for one of
the following subforms:
Typical aura with migraine headache
Typical aura with nonmigraine pain
Typical aura without headache
Familial hemiplegic migraine
Sporadic hemiplegic migraine
Basilar type migraine
• C. Not attributed to another disorder.
z
Childhood periodic syndromes
( precursors of migraine according to revised
HS criteria)
• Cyclic vomiting syndrome.
• Abdominal migraine.
• Benign paroxismal vertigo of childhood.
z
Clinical Evaluation
• Salient points in History
1. Headache characteristics
2. Trigger factors
3. Warning symptoms
4. Symptoms during attack
5. Relieving factors
6. Symptoms between attack
7. Family history
z
 Pattern of headache
1. Acute
2. Acute Recurrent
3. Chronic Progressive
4. Chronic Non-progressive
z
 Clues from clinical evaluation
1. Fever – URI and systemic infection
2. Weight loss – malignancy/tuberculosis
3. Neck rigidity – meningitis
4. Hypertension – renal/adrenal cause
5. Injuries – Trauma
z
Red Flag Signs
 Systemic signs and symptoms
 Neurologic signs and symptoms
 Sudden onset
 Occipital location
 Change in character of headache
 Age <6 years
z
When to perform neuroimaging
study ??
• Age < 6 years
• Abnormal neurological exam
• Chronic progressive pattern
• Family reassurance
z
MRI Vs CT
There was no sufficient data to make a
specific recommendation regarding
the relative sensitivity of MRI compar
ed with CT.
Most prefer MRI because of vascular
differential diagnosis.
z
EEG and migraine
• EEG is not indicated in the routine
evaluation of headache
• It is performed if seizures are
suspected.
z
Management of migraine
• Non-pharmacologic methods
1.Headache education
2.Lifestyle modification (Sleep,Meals,
Activity, Relaxation,Trigger avoidanc
e)
3.Biofeedback therapy (Relaxation
techniques, Hypnosis, Acupuncture,
Massage therapy)
z
Pharmacologic Treatment
• General pain medications
(acetaminophen, NSAIDS) alone or
in combination with antiemetic medi
cations
• Triptans-5HT1D agonists (Rizatriptan
, Almotriptan)
z
Indications for migraine
prophylaxis
• Attacks occur >2-4 times per month
• Disability occurs > 3 days per month
• Duration of attack > 48 h
• Medications for acute attack are ineff
ective, C.I or overused
• Attacks produce prolonged aura or
true migrainous infarction
• Patient preference
z
Duration of prophylactic
therapy
• The optimum duration of prophylact
ic therapy is uncertain
• The approach is to treat for 4-6 mo
nths and then taper over the course
of several weeks.
z
Preventive Therapy
• B blockers (Propranolol)
• Antihistaminic ( Cyproheptadine)
• Anticonvulsants (Topiramate, Valproi
c acid)
• Ca channel blocker (Flunarizine)
z
Key Messages
 History and detailed clinical examination
 Migraine is clinical diagnosis
 Identify Red Flags
 Neuroimaging only in suspected
secondary headache
 Lifestyle modification is an important part
of management
z
Thank you !

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migraine.pptx

  • 1. MIGRAINE - A HEADACHE FOR PAEDIATRICIAN Dr. Muzammil Koshish MBBS DCH DNB(PAEDIATRICS)
  • 2. z Headache classification • Primary headache migraine, tension , cluster • Secondary headache Infection, trauma, hemorrhage, tumor, high intracranial pressure. • Cranial neuropathies
  • 3. z Migraine • Episodic, periodic, paroxysmal attacks of modera te to severe throbbing pain, separated by pain free intervals, • Associated with nausea, vomiting, photophobia, abdominal pain and desire to sleep, motion sickn ess. • Family history 70-90%
  • 4. z Classification of migraine (revised international headache society IHS 2004) • Migraine without aura • Migraine with aura
  • 5. z Migraine without aura (IHS 2004) • A. at least 5 attacks fulfilling criteria B through D. • B. Headache attacks lasting 4 to 72h • C. headache has at least 2 of the following -unilateral location -pulsating quality -moderate or severe pain intensity -aggravation by or causing avoidence of routine physical activity • D. during headache at least one of the folowing: nausea, vomiting, or both, photophobia, phonophobia • E. not attributed to another disorder.
  • 6. z Migraine with aura (IHS 2004) • A. at least 2 attacks fulfilling criteria B. • B. migraine aura fulfilling criteria B or C for one of the following subforms: Typical aura with migraine headache Typical aura with nonmigraine pain Typical aura without headache Familial hemiplegic migraine Sporadic hemiplegic migraine Basilar type migraine • C. Not attributed to another disorder.
  • 7. z Childhood periodic syndromes ( precursors of migraine according to revised HS criteria) • Cyclic vomiting syndrome. • Abdominal migraine. • Benign paroxismal vertigo of childhood.
  • 8. z Clinical Evaluation • Salient points in History 1. Headache characteristics 2. Trigger factors 3. Warning symptoms 4. Symptoms during attack 5. Relieving factors 6. Symptoms between attack 7. Family history
  • 9. z  Pattern of headache 1. Acute 2. Acute Recurrent 3. Chronic Progressive 4. Chronic Non-progressive
  • 10. z  Clues from clinical evaluation 1. Fever – URI and systemic infection 2. Weight loss – malignancy/tuberculosis 3. Neck rigidity – meningitis 4. Hypertension – renal/adrenal cause 5. Injuries – Trauma
  • 11. z Red Flag Signs  Systemic signs and symptoms  Neurologic signs and symptoms  Sudden onset  Occipital location  Change in character of headache  Age <6 years
  • 12. z When to perform neuroimaging study ?? • Age < 6 years • Abnormal neurological exam • Chronic progressive pattern • Family reassurance
  • 13. z MRI Vs CT There was no sufficient data to make a specific recommendation regarding the relative sensitivity of MRI compar ed with CT. Most prefer MRI because of vascular differential diagnosis.
  • 14. z EEG and migraine • EEG is not indicated in the routine evaluation of headache • It is performed if seizures are suspected.
  • 15. z Management of migraine • Non-pharmacologic methods 1.Headache education 2.Lifestyle modification (Sleep,Meals, Activity, Relaxation,Trigger avoidanc e) 3.Biofeedback therapy (Relaxation techniques, Hypnosis, Acupuncture, Massage therapy)
  • 16. z Pharmacologic Treatment • General pain medications (acetaminophen, NSAIDS) alone or in combination with antiemetic medi cations • Triptans-5HT1D agonists (Rizatriptan , Almotriptan)
  • 17. z Indications for migraine prophylaxis • Attacks occur >2-4 times per month • Disability occurs > 3 days per month • Duration of attack > 48 h • Medications for acute attack are ineff ective, C.I or overused • Attacks produce prolonged aura or true migrainous infarction • Patient preference
  • 18. z Duration of prophylactic therapy • The optimum duration of prophylact ic therapy is uncertain • The approach is to treat for 4-6 mo nths and then taper over the course of several weeks.
  • 19. z Preventive Therapy • B blockers (Propranolol) • Antihistaminic ( Cyproheptadine) • Anticonvulsants (Topiramate, Valproi c acid) • Ca channel blocker (Flunarizine)
  • 20. z Key Messages  History and detailed clinical examination  Migraine is clinical diagnosis  Identify Red Flags  Neuroimaging only in suspected secondary headache  Lifestyle modification is an important part of management