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Food Borne Diseases
 Diseases caused by microorganisms
through food
 Microorganisms can cause
Food spoilage
Diseases
Foodborne Diseases
Usually called “Food Poisoning”  caused by
eating the food contaminated with toxin.
 Two main types:
1. Toxin is produced in the food (exotoxin) causes
the disease called food poisoning
2. Food, being a mechanical carrier, carries
pathogens and cause disease on ingestion.
Food borne Pathogens
Gram Negative Bacteria
 Salmonella (Typhimurium and Enteritidis)
 Shigella
 Vibrio cholerae
Other Organisms
 Amoeba
Giardia lamblia
Entamoeba histolytica
Cryptosporidium
 Fungi 100s of poisonous mushrooms
Aspergillus  aflatoxins
Claviceps hallucinogens
 Algae certain marine algae produce
neurotoxins contaminate shell fish
Intoxication vs. Infection
Intoxication
 Manifested much
more quickly
 Toxin is already
present to cause
harm
 Toxin is the direct
cause of disease
Infection
 Pathogen has to be
ingested
 After a period of
incubation ,pathogen
establishes itself,
usually in the intestine
 Causes infection
Transmission of Foodborne Diseases
 4 main ways 4Fs
Food
Feces
Fingers
Flies
 Food is the immediate source of the
pathogen/toxin
 May be acquired by close contact with an
infected person or a carrier
 Involves the fecal-oral route
General Measures of Prevention
 Clean & store produce properly
 Prepare food properly cooking adequately
 Employ general sanitary procedures while
handling food
 Eat cooked food promptly
 Restrict carriers from food preparation
 Protect food from insects, rodents
 Use pure water
Prevention cont…
Based on the route of transmission two
main ways of prevention
1. Reduce the possibility of food handlers
contaminating food
( education in general hygiene)
2. Keep cold foods cold, hot foods hot
( serve foods when prepared or keep
refrigerated, do not allow foods to sit at
room temperature)
Food Poisoning
Staphylococcal Food Poisoning
 Staphylococcus aureus  gm +ve
 Humans harbor these organisms, present in
boils, skin lesions
 Food poisoning is caused when staph is
transferred from person to food
Could come from an open boil, lesions sneeze, etc
Staphylococcal Food Poisoning
 Exotoxins are heat stable proteins known as
enterotoxins (affecting the intestines)
 Inhibit water absorption from the intestine &
induce diarrhea & vomiting
 Damages the intestinal lining colitis
 Nausea, vomiting, abdominal cramps, diarrhea
Onset 1-6 hours after eating the contaminated
food
Clostridium botulinum & Botulism
 C. botulinum Gm(+) , endospore
forming organism, anaerobic
 Present in soil, ponds and lakes
Botulism
 Infrequent, but fatal
 Caused by exotoxins produced by
C. botulinum most deadly
biological toxin neurotoxin and
affects the CNS
Prevention
 Endospores present may not be
removed by washing
 Proper canning
 After canning avoid bulging
can/jar
Clostridium perfringes
 Anaerobic spore former
 Present in soil & intestines of humans and
animals hence also in sewage
 Typical illness diarrhea, abdominal cramps,
nausea and vomiting
 Sickness lasts a day, incubation period is
usually 6—24 hours
 Prevention: refrigerate food and cook
adequately

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Microbiology in everyday life By Shan Ali

  • 1.
  • 2. Food Borne Diseases  Diseases caused by microorganisms through food  Microorganisms can cause Food spoilage Diseases
  • 3. Foodborne Diseases Usually called “Food Poisoning”  caused by eating the food contaminated with toxin.  Two main types: 1. Toxin is produced in the food (exotoxin) causes the disease called food poisoning 2. Food, being a mechanical carrier, carries pathogens and cause disease on ingestion.
  • 4. Food borne Pathogens Gram Negative Bacteria  Salmonella (Typhimurium and Enteritidis)  Shigella  Vibrio cholerae
  • 5. Other Organisms  Amoeba Giardia lamblia Entamoeba histolytica Cryptosporidium  Fungi 100s of poisonous mushrooms Aspergillus  aflatoxins Claviceps hallucinogens  Algae certain marine algae produce neurotoxins contaminate shell fish
  • 6. Intoxication vs. Infection Intoxication  Manifested much more quickly  Toxin is already present to cause harm  Toxin is the direct cause of disease Infection  Pathogen has to be ingested  After a period of incubation ,pathogen establishes itself, usually in the intestine  Causes infection
  • 7. Transmission of Foodborne Diseases  4 main ways 4Fs Food Feces Fingers Flies  Food is the immediate source of the pathogen/toxin  May be acquired by close contact with an infected person or a carrier  Involves the fecal-oral route
  • 8. General Measures of Prevention  Clean & store produce properly  Prepare food properly cooking adequately  Employ general sanitary procedures while handling food  Eat cooked food promptly  Restrict carriers from food preparation  Protect food from insects, rodents  Use pure water
  • 9. Prevention cont… Based on the route of transmission two main ways of prevention 1. Reduce the possibility of food handlers contaminating food ( education in general hygiene) 2. Keep cold foods cold, hot foods hot ( serve foods when prepared or keep refrigerated, do not allow foods to sit at room temperature)
  • 11. Staphylococcal Food Poisoning  Staphylococcus aureus  gm +ve  Humans harbor these organisms, present in boils, skin lesions  Food poisoning is caused when staph is transferred from person to food Could come from an open boil, lesions sneeze, etc
  • 12. Staphylococcal Food Poisoning  Exotoxins are heat stable proteins known as enterotoxins (affecting the intestines)  Inhibit water absorption from the intestine & induce diarrhea & vomiting  Damages the intestinal lining colitis  Nausea, vomiting, abdominal cramps, diarrhea Onset 1-6 hours after eating the contaminated food
  • 13. Clostridium botulinum & Botulism  C. botulinum Gm(+) , endospore forming organism, anaerobic  Present in soil, ponds and lakes
  • 14. Botulism  Infrequent, but fatal  Caused by exotoxins produced by C. botulinum most deadly biological toxin neurotoxin and affects the CNS
  • 15. Prevention  Endospores present may not be removed by washing  Proper canning  After canning avoid bulging can/jar
  • 16. Clostridium perfringes  Anaerobic spore former  Present in soil & intestines of humans and animals hence also in sewage  Typical illness diarrhea, abdominal cramps, nausea and vomiting  Sickness lasts a day, incubation period is usually 6—24 hours  Prevention: refrigerate food and cook adequately