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Antibiotics. General
characteristics and
Classification.
BY : HARSHITA HADA , 232E
Table of contents
ANTIBIOTICS
GENERAL
CLASSIFICATION
CLASSIFICATION
Conclusions
01
02
03
04
INTRODUCTION TO
ANTIBIOTICS
BASIC CHARACTERISTICS
AND CLASSFICATIONS .
BASED ON CHEMICAL
COMPOSITION AND
MODE OF ACTION.
CONCLUSIONS ON THE
TOPIC ANTIBIOTICS AND
THEIR CLASSIFICATIONS.
ANTIBIOTICS
WHAT ARE ANTIBIOTICS?
01
Introduction
Antibiotics are a class of drugs that inhibit the
growth of or destroy bacteria. ( anti - against,
bios - life ).
They are essential for treating bacterial
infections.
Antibiotics came into worldwide prominence with the
introduction of penicillin in 1941. Since then they have
revolutionized the treatment of bacterial infections in
humans and other animals
GENERAL CHARACTERISTICS
Antibiotics are naturally
derived or synthetic
compounds
They target bacteria, not
viruses or fungi.
They can be administered orally,
topically, or intravenously.
Prescribed by healthcare
professionals
GENERAL CLASSIFICATION
•Antibacterial agents are any
compounds natural, synthetic, or
semi-synthetic that are clinically useful
in the treatment of bacterial infections.
•Bacteriostatic agents
(sulfonamides,chloramphenicol) inhibit
bacterial growth
•Bacteriocidal agents (penicillin,
streptomycin) significantly reduce the
number of viable bacteria in the
culture. Bactericidal agents generally
kill only growing organisms
CLASSIFICATION
•Narrow spectrum antibacterial
agents are preferentially active
against other Gram + or Gram-
bacteria
•Broad-spectrum antibacterial agents
are active against Gr+ and Gr-
bacteria
A
Research
Mercury is the smallest
planet of them all
Preclinical
Jupiter is the biggest planet
of them all
Experimentation
Despite being red, Mars is
a cold place
Results
Saturn is a gas giant with
several rings
CLASSIFICATION BASED ON
SPECTRUM OF ACTION
Conclusions
Neptune is very far from
the Sun
B C D E
CLASSIFICATION BASED ON SOURCE
Based on the nature of the source, antibiotics can be
grouped into the following:
(i) natural compounds obtained from
microorganisms;
(ii) semi-synthetic members that are structurally
modified natural products; and
(iii) synthetic products.
Natural antibiotics (benzylpenicillin,
cephalosporins and gentamicin) present a critical
inconvenience, high toxicity, whereas
semi-synthetic (ampicillin and amikacin) and
synthetic antibiotics (moxifloxacin and norfloxacin)
ones exhibit an augmented therapeutical effect and
a lower toxicity as compared to natural antibiotics
β-lactam
PENICILLIN STREPTOMYCIN
CEPHAL-_ GENTAMYCIN
SPORIN
Aminoglycoside
OXYTETRCYCLIN POLYMYXIN B
DOXYTETRACYC-
LIN
Tetracycline
AZITHROMYCIN
ERYTHROMYCIN
Polypeptide
SULPHONAMIDES
QUINOLONES ETC.
Classification based on chemical structure
Macrolide Other
—Someone Famous
“This is a quote, words full of
wisdom that someone
important said and can make
the reader get inspired.”
Conclusions
ANTIBIOTICS ARE CRUCIAL FOR TREATING BACTERIAL
INFECTIONS .
THEY CAN BE CLASSIFIED BY DIFFERENT GROUPS BY
THEIR CHEMICAL COMPOSITION , MECHANISM OF
ACTION , THEIR SOURCE ETC.
ANTIBIOTIC RESISTANCE IS A GROWING CONCERN .
OVERUSE AND MISUSE CAN LEAD TO RESISTANCE .
PROPER USE AND STEWARDSHIP ARE ESSENTIAL.
CREDITS: This presentation template was
created by Slidesgo, including icons by
Flaticon and infographics & images by Freepik
By : HARSHITA HADA , 232E
Thank you
for your
attention .

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Microbiology_ ANTIBIOTICS , HARSHITA HADA 232E. .pdf

  • 2. Table of contents ANTIBIOTICS GENERAL CLASSIFICATION CLASSIFICATION Conclusions 01 02 03 04 INTRODUCTION TO ANTIBIOTICS BASIC CHARACTERISTICS AND CLASSFICATIONS . BASED ON CHEMICAL COMPOSITION AND MODE OF ACTION. CONCLUSIONS ON THE TOPIC ANTIBIOTICS AND THEIR CLASSIFICATIONS.
  • 4. Introduction Antibiotics are a class of drugs that inhibit the growth of or destroy bacteria. ( anti - against, bios - life ). They are essential for treating bacterial infections. Antibiotics came into worldwide prominence with the introduction of penicillin in 1941. Since then they have revolutionized the treatment of bacterial infections in humans and other animals
  • 5. GENERAL CHARACTERISTICS Antibiotics are naturally derived or synthetic compounds They target bacteria, not viruses or fungi. They can be administered orally, topically, or intravenously. Prescribed by healthcare professionals
  • 6. GENERAL CLASSIFICATION •Antibacterial agents are any compounds natural, synthetic, or semi-synthetic that are clinically useful in the treatment of bacterial infections. •Bacteriostatic agents (sulfonamides,chloramphenicol) inhibit bacterial growth •Bacteriocidal agents (penicillin, streptomycin) significantly reduce the number of viable bacteria in the culture. Bactericidal agents generally kill only growing organisms
  • 7. CLASSIFICATION •Narrow spectrum antibacterial agents are preferentially active against other Gram + or Gram- bacteria •Broad-spectrum antibacterial agents are active against Gr+ and Gr- bacteria
  • 8. A Research Mercury is the smallest planet of them all Preclinical Jupiter is the biggest planet of them all Experimentation Despite being red, Mars is a cold place Results Saturn is a gas giant with several rings CLASSIFICATION BASED ON SPECTRUM OF ACTION Conclusions Neptune is very far from the Sun B C D E
  • 9. CLASSIFICATION BASED ON SOURCE Based on the nature of the source, antibiotics can be grouped into the following: (i) natural compounds obtained from microorganisms; (ii) semi-synthetic members that are structurally modified natural products; and (iii) synthetic products. Natural antibiotics (benzylpenicillin, cephalosporins and gentamicin) present a critical inconvenience, high toxicity, whereas semi-synthetic (ampicillin and amikacin) and synthetic antibiotics (moxifloxacin and norfloxacin) ones exhibit an augmented therapeutical effect and a lower toxicity as compared to natural antibiotics
  • 10. β-lactam PENICILLIN STREPTOMYCIN CEPHAL-_ GENTAMYCIN SPORIN Aminoglycoside OXYTETRCYCLIN POLYMYXIN B DOXYTETRACYC- LIN Tetracycline AZITHROMYCIN ERYTHROMYCIN Polypeptide SULPHONAMIDES QUINOLONES ETC. Classification based on chemical structure Macrolide Other
  • 11. —Someone Famous “This is a quote, words full of wisdom that someone important said and can make the reader get inspired.”
  • 12. Conclusions ANTIBIOTICS ARE CRUCIAL FOR TREATING BACTERIAL INFECTIONS . THEY CAN BE CLASSIFIED BY DIFFERENT GROUPS BY THEIR CHEMICAL COMPOSITION , MECHANISM OF ACTION , THEIR SOURCE ETC. ANTIBIOTIC RESISTANCE IS A GROWING CONCERN . OVERUSE AND MISUSE CAN LEAD TO RESISTANCE . PROPER USE AND STEWARDSHIP ARE ESSENTIAL.
  • 13. CREDITS: This presentation template was created by Slidesgo, including icons by Flaticon and infographics & images by Freepik By : HARSHITA HADA , 232E Thank you for your attention .