This document summarizes the benefits of ALGISIUM, a silanol compound that improves skin health in several ways:
1. ALGISIUM increases skin cell proliferation, collagen production, hydration and communication while preventing inflammation, glycation and damage from free radicals.
2. It stabilizes an organic silicium core that provides anti-aging benefits and additional benefits depending on the stabilizing molecule.
3. Studies show ALGISIUM stimulates keratinocyte and fibroblast activity, improves skin elasticity and firmness, and reduces signs of aging like wrinkles, eye bags and cellulite.
Collagen is the most important protein in the bodyKolagen24.pl
NATURAL COLLAGEN AND OTHER EPOCHAL, POLISH BIOTECHNOLOGICAL INVENTIONS PRODUCT CATALOG
Natural Collagen – The Protein of Life Natural Collagen The Protein Of Youth Cosmetic and medical benefits of Natural Collagen Nowadays Supplementation is a must not a luxury
Collagen is a protein commonly found in humans and animals. Collagen is the most important protein in the body, as it constitutes 30% of total human protein, 70% of skin protein, 30-60% of bones, 99% of eye protein and is the main component of connective tissue.
Collagen Select is a food supplement aimed at maintaining beautiful, firm, and healthy skin through its 9-component formula containing VERISOL® collagen hydrolysate, which contributes to increased skin elasticity and reduction of wrinkles. Collagen Select supports collagen production to improve the health of skin, hair, and nails while also keeping mucous membranes healthy. It helps delay the aging process by neutralizing free radicals to protect cells and promote a healthy, youthful appearance.
According to dermatologists, collagen is a skin protein. It is responsible for skin strength, elasticity, its well-defined structure, and firmness. In other words, collagen keeps the skin youthful.
This document discusses causes and treatments for cellulite. It states that cellulite affects over 85% of women and is caused by a combination of factors including the connective tissue architecture, hormones, circulation issues, diet, genetics, inflammation, and a sedentary lifestyle. It then evaluates and rates various treatment options for cellulite including vigorous massage, LPG Endermologie, topical creams, and mesotherapy. Topical creams are found to have only temporary and partial effects while Endermologie and targeted exercise programs show more promising longer-term results.
Apple Stem Cell PLus - Your Solutions For Skin ProblemJovito Oracion
This document provides information about a business opportunity with BiogreenScience in the Philippines. It summarizes that millions of people are looking for more time with family, extra income, freedom from debt, and a balanced lifestyle. Through BiogreenScience, individuals can find these things and help others. The business opportunity allows people to earn income quickly through their own home-based business. The document then provides details about the company's products that meet consumer needs for nutrition and financial well-being. It encourages readers to become part of BiogreenScience and reach new levels of success.
Ampelopsin (Dihydromyricetin) from Ampelopsis Grossedentata acts in three ways 1).Lipogenesis inhibition 2).Lipolysis stimulation and 3).Adipogenesis decrease.
Dihydromyricetin, a type of avonols, is a major bioactive component in Ampelopsis grossedentata. Scientic research has suggested that Dihydromyricetin can be used as cosmetic ingredient for body slimming. With substantiated activity on the lipid metabolism of the adipocyte. It is suitable to be formulated into any kind of anti-cellulite, slimming and/or body modelling cosmetic treatment . Traditionally, active compounds acting only on the two pathways (Lipogenesis inhibition & Lipolysis stimulation), usually via adrenergic receptors, such as caffeine, etc.
Differently from traditional cosmetic ingredients, Dihydromyricetin acts on three pathways 1).Lipogenesis inhibition: by reducing the synthesis of new triglyceride into the adipocytes. 2).Lipolysis stimulation: by activating degradation of triglycerides stored in the adipocytes. 3).Adipogenesis decrease: by suppressing cell differentiation from pre-adipocytes into mature adipocytes, thus preventing adipocyte cell renovation and reducing triglyceride accumulation.
With the aboved triple-action. It is also scientifically demonstrated and based on a new mechanism of action on the adipocyte metabolism. Marked decrease of adipogenesis and lipogenesis as well as increase of lipolysis makes it a novel molecule applicable in cosmetic products aimed at both prevention and treatment as well as keep-fit.
Collagen comprises of about one third of total protein of our body
Collagen peptide ingestion results in more collagen-producing cells and increases the density of collagen in the skin.
Nizona’s Collagen Peptide has been clinically tested in Japan. Use of hydrolyzed collagen improves skin suppleness, hydration and elasticity which allows its users to look younger and be healthier.
Hydrolyzed collagen contains 20 amino acids, predominantly glycine, proline and hydroxyproline
Hydrolyzed collagen is absorbed as amino acids and small peptides in the blood
Hydrolyzed Japanese collagen reduces wrinkles and results in significant improvement in wrinkle depth, improvement in elasticity and hydration of the skin
Beauty Nectar Collagen Drink is the anti-aging solution for all your aging issues. Reduce wrinkles and get Glowing skin with best Collagen Drink by Ashieda.
Collagen is the most important protein in the bodyKolagen24.pl
NATURAL COLLAGEN AND OTHER EPOCHAL, POLISH BIOTECHNOLOGICAL INVENTIONS PRODUCT CATALOG
Natural Collagen – The Protein of Life Natural Collagen The Protein Of Youth Cosmetic and medical benefits of Natural Collagen Nowadays Supplementation is a must not a luxury
Collagen is a protein commonly found in humans and animals. Collagen is the most important protein in the body, as it constitutes 30% of total human protein, 70% of skin protein, 30-60% of bones, 99% of eye protein and is the main component of connective tissue.
Collagen Select is a food supplement aimed at maintaining beautiful, firm, and healthy skin through its 9-component formula containing VERISOL® collagen hydrolysate, which contributes to increased skin elasticity and reduction of wrinkles. Collagen Select supports collagen production to improve the health of skin, hair, and nails while also keeping mucous membranes healthy. It helps delay the aging process by neutralizing free radicals to protect cells and promote a healthy, youthful appearance.
According to dermatologists, collagen is a skin protein. It is responsible for skin strength, elasticity, its well-defined structure, and firmness. In other words, collagen keeps the skin youthful.
This document discusses causes and treatments for cellulite. It states that cellulite affects over 85% of women and is caused by a combination of factors including the connective tissue architecture, hormones, circulation issues, diet, genetics, inflammation, and a sedentary lifestyle. It then evaluates and rates various treatment options for cellulite including vigorous massage, LPG Endermologie, topical creams, and mesotherapy. Topical creams are found to have only temporary and partial effects while Endermologie and targeted exercise programs show more promising longer-term results.
Apple Stem Cell PLus - Your Solutions For Skin ProblemJovito Oracion
This document provides information about a business opportunity with BiogreenScience in the Philippines. It summarizes that millions of people are looking for more time with family, extra income, freedom from debt, and a balanced lifestyle. Through BiogreenScience, individuals can find these things and help others. The business opportunity allows people to earn income quickly through their own home-based business. The document then provides details about the company's products that meet consumer needs for nutrition and financial well-being. It encourages readers to become part of BiogreenScience and reach new levels of success.
Ampelopsin (Dihydromyricetin) from Ampelopsis Grossedentata acts in three ways 1).Lipogenesis inhibition 2).Lipolysis stimulation and 3).Adipogenesis decrease.
Dihydromyricetin, a type of avonols, is a major bioactive component in Ampelopsis grossedentata. Scientic research has suggested that Dihydromyricetin can be used as cosmetic ingredient for body slimming. With substantiated activity on the lipid metabolism of the adipocyte. It is suitable to be formulated into any kind of anti-cellulite, slimming and/or body modelling cosmetic treatment . Traditionally, active compounds acting only on the two pathways (Lipogenesis inhibition & Lipolysis stimulation), usually via adrenergic receptors, such as caffeine, etc.
Differently from traditional cosmetic ingredients, Dihydromyricetin acts on three pathways 1).Lipogenesis inhibition: by reducing the synthesis of new triglyceride into the adipocytes. 2).Lipolysis stimulation: by activating degradation of triglycerides stored in the adipocytes. 3).Adipogenesis decrease: by suppressing cell differentiation from pre-adipocytes into mature adipocytes, thus preventing adipocyte cell renovation and reducing triglyceride accumulation.
With the aboved triple-action. It is also scientifically demonstrated and based on a new mechanism of action on the adipocyte metabolism. Marked decrease of adipogenesis and lipogenesis as well as increase of lipolysis makes it a novel molecule applicable in cosmetic products aimed at both prevention and treatment as well as keep-fit.
Collagen comprises of about one third of total protein of our body
Collagen peptide ingestion results in more collagen-producing cells and increases the density of collagen in the skin.
Nizona’s Collagen Peptide has been clinically tested in Japan. Use of hydrolyzed collagen improves skin suppleness, hydration and elasticity which allows its users to look younger and be healthier.
Hydrolyzed collagen contains 20 amino acids, predominantly glycine, proline and hydroxyproline
Hydrolyzed collagen is absorbed as amino acids and small peptides in the blood
Hydrolyzed Japanese collagen reduces wrinkles and results in significant improvement in wrinkle depth, improvement in elasticity and hydration of the skin
Beauty Nectar Collagen Drink is the anti-aging solution for all your aging issues. Reduce wrinkles and get Glowing skin with best Collagen Drink by Ashieda.
This document discusses collagen and its use in cosmetics. It begins with a brief history of cosmetics use dating back to ancient Egypt and China. It then discusses the key ingredients in cosmetics including bases, coloring agents, and additives. It focuses on creams as a type of cosmetic, describing their composition and emulsion types. The bulk of the document is dedicated to collagen, describing its structure, functions, sources and role in skin health. It discusses how collagen is used in anti-aging cosmetics and the importance of maintaining its triple helix structure for effectiveness when applied topically.
Collagen : Foundation of youth or edible hoax - DR Naveen (BDS)Dr Naveen Gokul R
SAVEETHA INTERNATIONAL CONFERENCE 2018
SECURED 1ST PLACE
Guided by - Prof PRISCILLA (biochemistry)
Collagen is the main structural protein of the different connective tissues present in animals.
It is mostly found in fibrous tissues, such as tendons and ligaments, and is also abundant in the cornea, cartilage, bones, blood vessels, the gut, and intervertebral discs.
Collagen is the major insoluble fibrous protein found in the extracellular matrix of the skin, together with elastin and hyaluronic acid.
Reverse aging is one of the most important health benefits of collagen use
Cellulite is caused by fat deposits under the skin that give a dimpled appearance, especially on thighs and buttocks. It is most common in women due to hormonal factors. While many treatments claim to reduce cellulite, medical studies found no significant difference between cellulitic fat and normal fat. Endermologie and body wraps provide temporary water loss but effects are not long lasting. Liposuction and lipodissolve are more effective at permanently removing fat deposits that cause cellulite.
The document discusses cellulite, including its history, physiology, causes, grading stages, medical evaluation and treatments. It notes that cellulite is caused by fat deposits under the skin that give a dimpled appearance, mostly seen in women due to hormones. Early medical studies found no difference between cellulite fat and normal fat. A growing multi-billion dollar industry markets various anti-cellulite products and devices, though many claims lack scientific evidence and some products were found to have no effect or risks. Endermologie treatments showed some temporary reduction in body circumference in studies but require many sessions and ongoing maintenance.
1) Skinside is a new drinkable nutricosmetic from Switzerland that combines collagen peptides, vitamins, and milk serum to reduce wrinkles and increase collagen production from within.
2) While topical skincare products only affect the outer epidermis layer, Skinside provides nutrients that penetrate to the dermis layer through ingestion to promote collagen synthesis from within.
3) A clinical study of 50 people aged 20-85 showed that most users found Skinside noticeably improved skin texture and appearance with no side effects after 6-8 weeks of daily use.
This document discusses the negative effects of sugar consumption on skin health. It states that sugar provides no nutritional value and leads to overeating by not inducing satiety. When sugar circulates in the bloodstream, it attaches to proteins through a process called glycation, producing advanced glycation end products (AGEs) that cause collagen and elastin to become rigid and damaged, leading to wrinkles and sagging skin. The document recommends consuming a low-glycemic diet, exercising regularly, and taking antioxidants and supplements to reduce AGE formation and promote youthful skin.
This document discusses powerful anti-aging skin care products containing potent antioxidant combinations. It describes a line of products containing a vitamin C derivative and pomegranate extract that have been shown to have superior antioxidant activity. The products are said to help combat skin aging caused by oxidation, improving hydration, elasticity, clarity and reducing signs of damage like wrinkles and discoloration. Clinical tests showed the products increased skin radiance, uniformity and firmness for many users.
♥Revolutionary Anti-Aging Cosmetics
♥ No. 1 in the world! ♥ http://anti-age.tilda.ws/cosmetics
Amazing results without injections, plastic surgery or any other health risks. Thanks to the combination of three key ingredients – the hits of modern cosmetology – stem cells, bio-peptides, epidermal growth factors in one bottle!
This document provides information about Dr. Gene, a Korean skincare company. It lists the company's contact information, certifications obtained since 2010 for new skincare technology, and patented skincare devices. Product images and descriptions are presented for various skincare items containing stem cells and active hydrogen. Information is provided on the anti-aging benefits of hydrogen and how the company's hydrogen beauty device works. Key ingredients and their skin benefits are defined. Test results show the device and ingredients improve wrinkles and skin elasticity.
What happened if we do not help our own body to produce collagen?
Very simple, when you look at the mirror and you see those wrinkles that is not supposed to be there at your age.
KB Collagen is not just ordinary collagen that you can see in the market. Our collagen is made in japan specifically in hokkaido and it is coming from the Salmon Ovary Peptide (S.O.P) KB Collagen helps to slow down the aging process but increasing the production of the collagen in our body plus it has a finest quality pearl powder
uses by royals and even cleopatra long time ago for glowing skin.
KB Collagen is cost Php750 30tablets (3 x a day) Available in all Mercury drugs and other leading drugstores or Php1500 for 3 bottles promo available only in all Asian Massage & Asianskymall reseller.
Lastly, KB Collagen is a good combination with our KB Glutanac plus Rosehips for skin whitening. Price Php439 / 20caps Php1195/60caps
Open for distributorship.
This document is a 2015 company presentation for Skincode that outlines the company's philosophy, products, and clinical studies. It discusses Skincode's Swiss heritage and use of advanced technology in product development. The presentation describes Skincode's two product lines, key ingredients like CM-Glucan and ACR Complex G2, and clinical studies showing their anti-aging benefits. Maps and images showcase Skincode's global presence and retail stores.
Acti-Labs UK Ambassador, Shannan Johnson and Her Glam Squad, Southern Beauty, Offer
Surgery Like & Medically Inspired Treatments, Skincare, Body Care, Slimming Weight Loss and Cosmetics For Home Use
ShannanJohnson.com
The document discusses aging at the cellular level and strategies to combat it, introducing the [ProGEN-in] technology which uses active ingredients like a biomimetic peptide and Menyanthes trifoliata extract to inhibit progerin synthesis, protect vitamin C, and improve skin properties in the dermis. This technology is the basis for Skeyndor's Global Lift anti-aging treatment program that clinical results show provides a firming effect and attenuation of wrinkles through products used in salon sessions and continued at home.
Collagen is a fibrous protein found in connective tissues like bones, skin, and organs. It provides structure, strength, and firmness to tissues. As we age, collagen levels decrease, causing wrinkles and joint weakness. Collagen's structure involves hydrogen bonding between amino acids that forms collagen fibers. This hydrogen bonding gives collagen its strength and suitability for uses in tendons, bones, and skin.
Cellulite is the peak self-confidence giant among the women packed with fat wallet to take on their skin, creating protrusions to look. It is considered brought on by residing an motionless life structure and harmful diet, and toxic core and bad blood deliver pull together in the torso.
More Related Content
Similar to Mesoskinline-Algesium -Silicium for Skin Reconstruction
This document discusses collagen and its use in cosmetics. It begins with a brief history of cosmetics use dating back to ancient Egypt and China. It then discusses the key ingredients in cosmetics including bases, coloring agents, and additives. It focuses on creams as a type of cosmetic, describing their composition and emulsion types. The bulk of the document is dedicated to collagen, describing its structure, functions, sources and role in skin health. It discusses how collagen is used in anti-aging cosmetics and the importance of maintaining its triple helix structure for effectiveness when applied topically.
Collagen : Foundation of youth or edible hoax - DR Naveen (BDS)Dr Naveen Gokul R
SAVEETHA INTERNATIONAL CONFERENCE 2018
SECURED 1ST PLACE
Guided by - Prof PRISCILLA (biochemistry)
Collagen is the main structural protein of the different connective tissues present in animals.
It is mostly found in fibrous tissues, such as tendons and ligaments, and is also abundant in the cornea, cartilage, bones, blood vessels, the gut, and intervertebral discs.
Collagen is the major insoluble fibrous protein found in the extracellular matrix of the skin, together with elastin and hyaluronic acid.
Reverse aging is one of the most important health benefits of collagen use
Cellulite is caused by fat deposits under the skin that give a dimpled appearance, especially on thighs and buttocks. It is most common in women due to hormonal factors. While many treatments claim to reduce cellulite, medical studies found no significant difference between cellulitic fat and normal fat. Endermologie and body wraps provide temporary water loss but effects are not long lasting. Liposuction and lipodissolve are more effective at permanently removing fat deposits that cause cellulite.
The document discusses cellulite, including its history, physiology, causes, grading stages, medical evaluation and treatments. It notes that cellulite is caused by fat deposits under the skin that give a dimpled appearance, mostly seen in women due to hormones. Early medical studies found no difference between cellulite fat and normal fat. A growing multi-billion dollar industry markets various anti-cellulite products and devices, though many claims lack scientific evidence and some products were found to have no effect or risks. Endermologie treatments showed some temporary reduction in body circumference in studies but require many sessions and ongoing maintenance.
1) Skinside is a new drinkable nutricosmetic from Switzerland that combines collagen peptides, vitamins, and milk serum to reduce wrinkles and increase collagen production from within.
2) While topical skincare products only affect the outer epidermis layer, Skinside provides nutrients that penetrate to the dermis layer through ingestion to promote collagen synthesis from within.
3) A clinical study of 50 people aged 20-85 showed that most users found Skinside noticeably improved skin texture and appearance with no side effects after 6-8 weeks of daily use.
This document discusses the negative effects of sugar consumption on skin health. It states that sugar provides no nutritional value and leads to overeating by not inducing satiety. When sugar circulates in the bloodstream, it attaches to proteins through a process called glycation, producing advanced glycation end products (AGEs) that cause collagen and elastin to become rigid and damaged, leading to wrinkles and sagging skin. The document recommends consuming a low-glycemic diet, exercising regularly, and taking antioxidants and supplements to reduce AGE formation and promote youthful skin.
This document discusses powerful anti-aging skin care products containing potent antioxidant combinations. It describes a line of products containing a vitamin C derivative and pomegranate extract that have been shown to have superior antioxidant activity. The products are said to help combat skin aging caused by oxidation, improving hydration, elasticity, clarity and reducing signs of damage like wrinkles and discoloration. Clinical tests showed the products increased skin radiance, uniformity and firmness for many users.
♥Revolutionary Anti-Aging Cosmetics
♥ No. 1 in the world! ♥ http://anti-age.tilda.ws/cosmetics
Amazing results without injections, plastic surgery or any other health risks. Thanks to the combination of three key ingredients – the hits of modern cosmetology – stem cells, bio-peptides, epidermal growth factors in one bottle!
This document provides information about Dr. Gene, a Korean skincare company. It lists the company's contact information, certifications obtained since 2010 for new skincare technology, and patented skincare devices. Product images and descriptions are presented for various skincare items containing stem cells and active hydrogen. Information is provided on the anti-aging benefits of hydrogen and how the company's hydrogen beauty device works. Key ingredients and their skin benefits are defined. Test results show the device and ingredients improve wrinkles and skin elasticity.
What happened if we do not help our own body to produce collagen?
Very simple, when you look at the mirror and you see those wrinkles that is not supposed to be there at your age.
KB Collagen is not just ordinary collagen that you can see in the market. Our collagen is made in japan specifically in hokkaido and it is coming from the Salmon Ovary Peptide (S.O.P) KB Collagen helps to slow down the aging process but increasing the production of the collagen in our body plus it has a finest quality pearl powder
uses by royals and even cleopatra long time ago for glowing skin.
KB Collagen is cost Php750 30tablets (3 x a day) Available in all Mercury drugs and other leading drugstores or Php1500 for 3 bottles promo available only in all Asian Massage & Asianskymall reseller.
Lastly, KB Collagen is a good combination with our KB Glutanac plus Rosehips for skin whitening. Price Php439 / 20caps Php1195/60caps
Open for distributorship.
This document is a 2015 company presentation for Skincode that outlines the company's philosophy, products, and clinical studies. It discusses Skincode's Swiss heritage and use of advanced technology in product development. The presentation describes Skincode's two product lines, key ingredients like CM-Glucan and ACR Complex G2, and clinical studies showing their anti-aging benefits. Maps and images showcase Skincode's global presence and retail stores.
Acti-Labs UK Ambassador, Shannan Johnson and Her Glam Squad, Southern Beauty, Offer
Surgery Like & Medically Inspired Treatments, Skincare, Body Care, Slimming Weight Loss and Cosmetics For Home Use
ShannanJohnson.com
The document discusses aging at the cellular level and strategies to combat it, introducing the [ProGEN-in] technology which uses active ingredients like a biomimetic peptide and Menyanthes trifoliata extract to inhibit progerin synthesis, protect vitamin C, and improve skin properties in the dermis. This technology is the basis for Skeyndor's Global Lift anti-aging treatment program that clinical results show provides a firming effect and attenuation of wrinkles through products used in salon sessions and continued at home.
Collagen is a fibrous protein found in connective tissues like bones, skin, and organs. It provides structure, strength, and firmness to tissues. As we age, collagen levels decrease, causing wrinkles and joint weakness. Collagen's structure involves hydrogen bonding between amino acids that forms collagen fibers. This hydrogen bonding gives collagen its strength and suitability for uses in tendons, bones, and skin.
Cellulite is the peak self-confidence giant among the women packed with fat wallet to take on their skin, creating protrusions to look. It is considered brought on by residing an motionless life structure and harmful diet, and toxic core and bad blood deliver pull together in the torso.
Similar to Mesoskinline-Algesium -Silicium for Skin Reconstruction (20)
2. CH
I N A C O
M
PLIANT
www.exsymol.com
.Increases skin cell proliferation
.Stimulates collagen production
.Improves cell communication
.Preserves skin hydration
.Stimulates lipolysis
.Prevents inflammation
.Prevents glycation
.Protects skin cells from free radicals
Detailed scientific files are available on demand for each of these benefits.
INCI name: METHYLSILANOL MANNURONATE
Silanols is a family of compounds where all members share
the same core of organic silicium. However, this silicium is
prone to polymerization that will lead to a loss of activity.
It is therefore mandatory to stabilize this organic silicium
core in order to ensure an optimal activity.
The silanol technology relies on exchangeable molecules to
stabilize the organic silicium core and, with each different
molecule chosen to stabilize this core, we have a different,
more specialized silanol.
ALGISIUM is the father of the silanol family. Its organic
silicium core is stabilized with alginic acid that has virtually
no cosmetic benefits. All of ALGISIUM’s benefits therefore
come from the organic silicium core only.
Active molecule Active molecule
Active molecule
Organic
silicium
core
STABILIZATION
Si Cafeine+
CAFEISILANE
For anti-aging benefits coupled
with strong slimming benefits
For anti-aging benefits coupled
with strong soothing benefits
Si Salicylic acid+
D.S.B. C
Si Hyaluronic acid+
For strong anti-aging benefits in
all skin compartments
EPIDERMOSIL
Because all silanols have the same core of organic silicium, they also have all the benefits it provides. However, depending on which
molecule the silicium core is stabilized with, we can have additional and specific benefits.
Silicium is an essential component of the skin. Indeed, by
interacting with structure and elastic proteins within the
dermis such as collagen fibers,elastin and proteoglycans,the
silicium insures optimal skin organization and architecture.
Furthermore, many studies show that silicium is capable
of stimulating skin cell metabolism for enhanced cell
proliferation and activity (e.g. collagen production,
contraction ability…).
However, with age the amount of silicium naturally present
in the skin tends to decrease. As a result, an overall
collapse of the skin architecture will happen, which will in
turn induce skin metabolism slow down, inevitably leading
to wrinkles.
With the silanol technology, we replenish the natural pool
of silicium hence allowing a complete skin restructuration
for global benefits at all levels.
Alginic acid Alginic acid
Alginic acid
Organic
silicium
core
SPECIALIZATION
Wrinkles
Time
Silanol
www.exsymol.com
.Anti-aging
.Anti-wrinkle
.Eye contour
.Hydration
.Anti-cellulite
.Slimming
.Firming
.Hydration
3. www.exsymol.comwww.exsymol.com
With age, there are more and more adipocytes (fat storing
cells). This causes a fat accumulation leading for example
to cellulite on the body and eye bags on the face.
ALGISIUM stimulates adipocite ability to get rid of the
fat by improving lipolysis. A treatment with ALGISIUM
improves three folds the amount of fat released by
adipocytes. Cellulite is strongly reduced, skin is firmer and
eye bags are reduced.
Because of aging, keratinocytes have a lower proliferation
rate that slowly leads to an epidermis thinning and eventually
weakens skin protection and reduce skin hydration because
of an increased transepidermis water loss.
ALGISIUM improves the number of proliferative
keratinocytes (in bright green) in human reconstructed
epidermis.That leads to a thickening of the epidermis for
a skin that will be better protected and better hydrated.
The dermal epidermal junction (DEJ) is the interface
between both skin compartments. It is responsible for
skin cohesion.With age, the DEJ becomes thinner and can
be duplicated, hence leading to a loss of cohesion and a
decreased cell communication.
ALGISIUM is capable of improving collagen VII (in green)
expression, one of the key constituent of the DEJ in human
skin explants. This leads to an improved skin cohesion and
skin cell communication.
With age,all metabolisms tend to slow down.In the dermis
this results in a lower proliferation rate and a lower activity
of fibroblasts.There are too few collagen fibers and the skin
is flaccid and wrinkled.
ALGISIUM stimulates fibroblast number and activity.
In the dermis, there will be more fibroblasts and each one
of them will produce more collagen. This strong collagen
booster effect leads to a firmer and more elastic skin.
Wrinkles are filled and erased.
HYPODERMIS
Reduced cellulite
Leaner body
DERMIS
Improved elasticity
Filled wrinkles
EPIDERMIS
Better protection
Better hydration
Keratinocyteproliferation
(%ofcontrol)
Control OSC
eq. ALGISIUM
(5%)
130
120
110
100
90
CollagenVIIexpression
(%ofcontrol)
Control OSC
eq. ALGISIUM
(5%)
130
120
110
100
90
Fatreleased
(%ofcontrol)
Young cells
(10% FCS)
300
200
100
0
ALGISIUM
(3%)
DEJ
Better cohesion
Better cell
communication
+20%
+20%
+163%
Control Organic silicium core
Control Organic silicium core
Control Organic silicium core
Keratinocytes have the ability to support
fibroblast proliferation by secreting
cytokines that will go from the epidermis
through the DEJ and into the dermis
where fibroblasts are located. With
age, this cross-communication decreases
and keratinocytes lose this ability to
support fibroblast proliferation. That
leads to a generalized impairment of skin
architecture.
ALGISIUM stimulates keratinocyte’s
ability to support fibroblast proliferation
and therefore restores an optimal cell
communication for global benefits.
Collagenproduction
(%ofcontrol)
Young cells
(10% FCS)
200
100
80
60
40
20
0
Aged cells
(2% FCS)
ALGISIUM
(2.5%)Aged cells
(3% FCS)
ALGISIUM
(0.01%)
ALGISIUM
(0.1%)
200
150
100
50
0
Fibroblastnumber
(%ofcontrol)
+15%
+96%
+165%
Fibroblastproliferation
(%ofcontrol)
Fibroblasts alone
(10% FCS)
200
150
100
50
0
+ aged
keratinocytes
+ ALGISIUM
(1%)
+ ALGISIUM
(1.5%)
+93%
+41%
+60%
Because of aging, the whole skin
architecture is altered, and this is
especially true within the dermis as
the thick dark collagen bundles ( )
observed in a younger skin completely
vanish.
Because of the silicium ability to
stimulate fibroblast combined with its
affinity for collagen fibers, a treatment
with ALGISIUM leads to a complete
reorganization of skin fibers for strong
and long lasting rejuvenation effect.
Control
Aged + MTS
Aged + OSC (eq. 4% ALGISIUM)Young Aged
Epidermis
Dermis
Epidermis Epidermis
Dermis Dermis
DEJ
DEJ
DEJ
4. www.exsymol.comwww.exsymol.com
Monomethylsilanetriol 0.3%
Including organic SILICIUM 0.09%
Mannuronic acid 0.6%
Water and preservative (sqf) 100%
Limpid and colorless liquid.
Miscible with water, alcohol and glycol.
Not miscible in oil.
Different preservative systems are available in order to fit with
your requirements. Please contact us for additional details about the
available versions.
ALGISIUM is perfectly tolerated. Tolerance and toxicity studies were
performed using both in vitro (cell culture and reconstructed epidermis)
and in vivo (human volunteers) methods.
Advised doses: 3 to 6%.
ALGISIUM is not temperature sensitive.
Formula pH: 4 to 7.
ALGISIUM is not compatible with high concentrations of calcium salts,
alcohol and glycols.
ALGISIUM is available in 5, 30 kg drums and 1 ton container (IBC).
CH
I N A C O
M
PLIANT
Thanks to ALGISIUM’s restructuration properties, global
of the treatment at 28 days.
Realized under dermatological control, this test was
performed on 10 women aged 25 to 35. All volunteers
received a treatment with ALGISIUM (5%) for ten weeks.
by the end of the treatment.
Ten volunteers aged 28 to 52 received a treatment with
ALGISIUM (6%) and we measured skin hydration only
minutes after a treatment. A dramatic improvement of skin
hydration with a strong long lasting effect was measured.
Before After
Mature skin
(50+)
Deep wrinkles
Adult skin
(40+)
Expression lines
Young skin
(30+)
Skin tone
D14
D28
Improvement(%)
Moisturization
Softness
Luminosity
Radiance
General aspect
30
25
20
15
10
5
0
D14
D28
Placebo
ALGISIUM(5%)
-3.5
-4.4
-1.7
-0.6
Waist Hip Thigh Knee
0
-1
-2
-3
-4
-5
Cirtometry(cm)
Placebo
ALGISIUM(6%)
Corneometryunit
100
90
80
70
60
50
0 100 200 300 400
Time (min)
At different age, different problems arise. Thanks to
ALGISIUM’s global benefits, specific problems to all skin
type is treated and solved.
Realized under dermatological control, this test was performed on 35 women aged 32 to 60.
All volunteers received a facial treatment with ALGISIUM (5%) twice a day for 28 days.
+20% after 2h
+37% after 6h