Libelium IoT to promote democracy and transparencyJ On The Beach
The aim of the Internet of Things is to provide valuable information about everything around us. Citizens demand open access to know directly what happens in their cities without any intermediary. But nowadays we are impacted by countless news our sources and is very difficult to digest it.
Over-information is the new way of hiding information. If we demand context and facts instead of dumb numbers, the biggest legacy of the internet of things will be a world that is more transparent and democratic. Smart solutions also improve citizens daily lives by controlling pollution levels, providing alerts against medical epidemics or managing cities' traffic.
Libelium technology has been applied worldwide. During Fukushima crisis after the tsunami in 2011 we developed a sensor board to measure radiation. As a result, a series of boards were shipped at no charge to the Tokyo Hackerspace and other working groups in Japan to allow citizens monitoring autonomously radiation levels. With MySignals, an eHealth development platform, we want to cover one of the main challenges of the century: enhancing the universal accessibility to a healthcare system for more than 2 billion people worldwide.
Presentato al sesto WebMeetup del Machine Learning / Data Science Meetup Roma: https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/273089965/
Presentazione per il sesto WebMeetup del Machine Learning / Data Science Meetup Roma: https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/273089965/
Libelium IoT to promote democracy and transparencyJ On The Beach
The aim of the Internet of Things is to provide valuable information about everything around us. Citizens demand open access to know directly what happens in their cities without any intermediary. But nowadays we are impacted by countless news our sources and is very difficult to digest it.
Over-information is the new way of hiding information. If we demand context and facts instead of dumb numbers, the biggest legacy of the internet of things will be a world that is more transparent and democratic. Smart solutions also improve citizens daily lives by controlling pollution levels, providing alerts against medical epidemics or managing cities' traffic.
Libelium technology has been applied worldwide. During Fukushima crisis after the tsunami in 2011 we developed a sensor board to measure radiation. As a result, a series of boards were shipped at no charge to the Tokyo Hackerspace and other working groups in Japan to allow citizens monitoring autonomously radiation levels. With MySignals, an eHealth development platform, we want to cover one of the main challenges of the century: enhancing the universal accessibility to a healthcare system for more than 2 billion people worldwide.
Presentato al sesto WebMeetup del Machine Learning / Data Science Meetup Roma: https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/273089965/
Presentazione per il sesto WebMeetup del Machine Learning / Data Science Meetup Roma: https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/273089965/
Paolo Galeone - Dissecting tf.function to discover auto graph strengths and s...MeetupDataScienceRoma
Original presentation available on GitHub: https://pgaleone.eu/tf-function-talk/
Meetup: https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/264338606/
Multimodal AI Approach to Provide Assistive Services (Francesco Puja)MeetupDataScienceRoma
Presentazione dal Meetup del Machine Learning / Data Science Meetup di Roma - Giugno 2019:
https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/262120815/
Presentazione dal Meetup del Machine Learning / Data Science Meetup di Roma - Giugno 2019:
https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/262120815/
Zero, One, Many - Machine Learning in Produzione (Luca Palmieri)MeetupDataScienceRoma
Talk dal Meetup del Machine Learning / Data Science Meetup di Roma - Giugno 2019:
https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/262120815/
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Paolo Galeone - Dissecting tf.function to discover auto graph strengths and s...MeetupDataScienceRoma
Original presentation available on GitHub: https://pgaleone.eu/tf-function-talk/
Meetup: https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/264338606/
Multimodal AI Approach to Provide Assistive Services (Francesco Puja)MeetupDataScienceRoma
Presentazione dal Meetup del Machine Learning / Data Science Meetup di Roma - Giugno 2019:
https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/262120815/
Presentazione dal Meetup del Machine Learning / Data Science Meetup di Roma - Giugno 2019:
https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/262120815/
Zero, One, Many - Machine Learning in Produzione (Luca Palmieri)MeetupDataScienceRoma
Talk dal Meetup del Machine Learning / Data Science Meetup di Roma - Giugno 2019:
https://www.meetup.com/it-IT/Machine-Learning-Data-Science-Meetup/events/262120815/
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
4. THE BIG HACK
25-26 NOVEMBRE, ROMA
IoT
IBM
2-3 DICEMBRE, MILANO
AI/MACHINELEARNING
PROSSIMI HACKATHON!
RESTA AGGIORNATO
MAGGIORI INFO
bit.ly/prossimihackathon