- ADC Review | Journal of Antibody-drug Conjugates | www.adcreview.com
- Onco' Zine | The International Oncology Network | www.oncozine.com
- The Onco'Zine Brief | Public Radio | https://www.oncozine.com/the-oncozine-brief-episodes/
- ADC Directory | A Guide to the World of Antibody-drug Conjugates | www.adcdirectory.com
- The Oncology Directory | www.oncologydirectory.com
The global anti-snoring & sleep apnea devices market was valued at US$ 7,399.7 million in 2015 and is forecast to grow to US$ 10,122.9 million by 2020 at a CAGR of 6.4% from 2016 to 2020.
Mouth ulcer treatment Market PPT 2021: Size, Growth, Demand and Forecast till...IMARC Group
According to the latest report by IMARC Group, the global mouth ulcer treatment market reached a value of US$ XX Billion in 2020.
Mouth ulcers are round or oval sores that occur on the mucous membrane of the oral cavity.
Asian hospitals and healthcare managementyahyasultan
The market for medical equipment and technology in Asia is booming. In excess of US$24 billion is being spent each year with major hospital construction projects underway in nearly all of the Asian countries. Government spending on the health sector is expected to grow at approximately 8-10% per annum.
Anal Cancer Therapeutics Market Competitive Research And Precise Outlook 2023...subishsam
The research firm Contrive Datum Insights has just recently added to its database a report with the heading global Anal Cancer Therapeutics Market .Both primary and secondary research methodologies have been utilised in order to conduct an analysis of the worldwide Anal Cancer Therapeutics Market . In order to provide a comprehensive comprehension of the topic at hand, it has been summed up using appropriate and accurate market insights. According to Contrive Datum Insights, this worldwide comprehensive report is broken up into several categories in order to present the data in a way that is understandable, succinct, and presented in a professional manner.
Circulating Tumor Cell, Cell Free DNA, Exosome and Vesicle Cancer Diagnostic ...MarketResearch.com
A revolution in cancer diagnostics is occurring using in vitro blood testing to identify cancer DNA. GRAIL, a new company with impressive backing, has announced a single blood test to detect all cancers. The technology is moving faster than the market. New technology that definitively identifies disease conditions from blood samples is poised to replace expensive invasive surgical biopsy procedures. The market is still in its infancy but has outstanding growth potential. The impact on the health care industry is enormous. The report forecasts the market size out to 2020. In addition, the report looks at potential market sizes by country, by cancer and by the three different opportunities: detection, management and screening.
Digital Health: Company presentation by Cristian Pascual, CEO and Co-founder of Mediktor, at the NOAH Conference London 2019, 30-31 October, Old Billingsgate.
The global anti-snoring & sleep apnea devices market was valued at US$ 7,399.7 million in 2015 and is forecast to grow to US$ 10,122.9 million by 2020 at a CAGR of 6.4% from 2016 to 2020.
Mouth ulcer treatment Market PPT 2021: Size, Growth, Demand and Forecast till...IMARC Group
According to the latest report by IMARC Group, the global mouth ulcer treatment market reached a value of US$ XX Billion in 2020.
Mouth ulcers are round or oval sores that occur on the mucous membrane of the oral cavity.
Asian hospitals and healthcare managementyahyasultan
The market for medical equipment and technology in Asia is booming. In excess of US$24 billion is being spent each year with major hospital construction projects underway in nearly all of the Asian countries. Government spending on the health sector is expected to grow at approximately 8-10% per annum.
Anal Cancer Therapeutics Market Competitive Research And Precise Outlook 2023...subishsam
The research firm Contrive Datum Insights has just recently added to its database a report with the heading global Anal Cancer Therapeutics Market .Both primary and secondary research methodologies have been utilised in order to conduct an analysis of the worldwide Anal Cancer Therapeutics Market . In order to provide a comprehensive comprehension of the topic at hand, it has been summed up using appropriate and accurate market insights. According to Contrive Datum Insights, this worldwide comprehensive report is broken up into several categories in order to present the data in a way that is understandable, succinct, and presented in a professional manner.
Circulating Tumor Cell, Cell Free DNA, Exosome and Vesicle Cancer Diagnostic ...MarketResearch.com
A revolution in cancer diagnostics is occurring using in vitro blood testing to identify cancer DNA. GRAIL, a new company with impressive backing, has announced a single blood test to detect all cancers. The technology is moving faster than the market. New technology that definitively identifies disease conditions from blood samples is poised to replace expensive invasive surgical biopsy procedures. The market is still in its infancy but has outstanding growth potential. The impact on the health care industry is enormous. The report forecasts the market size out to 2020. In addition, the report looks at potential market sizes by country, by cancer and by the three different opportunities: detection, management and screening.
Digital Health: Company presentation by Cristian Pascual, CEO and Co-founder of Mediktor, at the NOAH Conference London 2019, 30-31 October, Old Billingsgate.
CHI's 10th Annual Next Generation Dx Summit, August 20-24, 2018, Washington, DCJames Prudhomme
Next Generation Dx Summit has grown to more than 1,000 international diagnostic professionals working in the field and offers unparalleled insight from the comprehensive programming and networking with key opinion leaders in the industry. The event is unique in the marketplace. This year the coverage spans cell- and cell-free biopsies, commercialization, reimbursement, biomarkers and companion diagnostics for immunotherapy, point-of-care testing, infectious disease, microfluidics and precision medicine. Now in its tenth year, Next Generation Dx Summit is a must-attend event with complete coverage of the most timely and important issues for the industry.
Cancer Tumor Profiling Market Growth, Demand and Challenges of the Key Indust...IMARC Group
The global cancer tumor profiling market reached a value of US$ 9.38 Billion in 2021. Looking forward, IMARC Group expects the market to reach a value of US$ 18.22 Billion by 2027 exhibiting a growth rate (CAGR) of 11.20% during 2022-2027.
More Info:- https://www.imarcgroup.com/cancer-tumor-profiling-market
Latest investor deck for Avatr's seed campaign.
Our technology called Avatr is a unique AI technology that pools multiple sources of data to create a digital representation of a patient.
AVATR keeps the patient permanently connected with their doctor in real time, and delivers timely patient insights as and when the doctor needs it.
We have launched our MVP in Singapore, and are raising £300k for 10% equity
The Pharma Research 2018 Conference includes a wide range of Keynote presentations, Oral talks, Poster presentations, Symposia, Workshops, Exhibitions and Career development programs. The conference invites delegates from Leading Universities, Pharmaceutical companies, Formulation Scientists, Medical Devices, Researchers, Health care professionals, students, business delegates and Young researchers across the globe providing a better podium, interconnecting the latest research, technological developments in the arena as well as therapeutic aspects. Participating at Pharma Research 2018 International conference will be an excellent opportunity to meet eminent personalities in the fields of pharmaceutics and learn about the latest technological advancements.
Companyprofilesandconferences.com glad to promote a new report on "Digna Biotech, S.L. - Product Pipeline Analysis" which are focuses on the development and commercialization of robust clinical therapeutic candidates through partnerships with pharmaceutical companies.
HIV Drugs Market Competitive Research And Precise Outlook 2023 To 2030subishsam
The research firm Contrive Datum Insights has just recently added to its database a report with the heading global HIV Drugs Market .Both primary and secondary research methodologies have been utilised in order to conduct an analysis of the worldwide HIV Drugs Market . In order to provide a comprehensive comprehension of the topic at hand, it has been summed up using appropriate and accurate market insights. According to Contrive Datum Insights, this worldwide comprehensive report is broken up into several categories in order to present the data in a way that is understandable, succinct,
Overview of the Health B2B2C Ecosystem; Use Social Media as a Market Focus Tool; Measure Your Performance; American Health Insurance Reality; Lack of Doctor Relationship; PR is the New Primary Care Facilitator; For Health Marketers – End-users Matter; Innovation drives healthcare advances; Ways to Improve Health and Make Money; Medicine Is a Team Sport; Big Data- Allowing Individual Patients to Leverage The Many; Some Examples of What Works- Equashield, EarlySense, MD Anderson, LifePoint; 3D Systems; American Association for Cancer Research,
2014 Overview of significant trends in the life sciences (Biotechnology, Pharmaceutical, Device and Diagnostics) industry with Big Data in the Life Sciences featured articles.
ZenOnco.io :
"Saving lives from cancer"
We provide end-to-end care to cancer patients regarding both medical (surgery, chemo, radiation, advanced treatment) as well as complementary treatment (eg, Anti Cancer Diet, Medical Cannabis, Ayurveda, etc) to improve their quality of life and increase chances of cure.
We educate and empower patients and their caregivers, plan their treatment roadmap, standardize service providers, facilitate treatment for last-mile care delivery, connect with other survivors, and do regular follow-ups. We are leveraging technology to do this in a scalable manner. For instance, we were recognized at ESMO for launching the World’s first tool to generate free directional Integrative Oncology treatment reports (ZIOPAR). We have also recently launched a community platform to connect cancer patients, survivors & caregivers (akin to Quora for Integrative Oncology).
The cancer journey itself is long and complicated - we aspire to be a constant companion throughout this journey for any need and requirement to extend life and improve quality of life. We help with:
Medical treatment: Identifying which oncologist to meet, validating treatment opinions, getting high-quality affordable diagnostic tests, searching for best available hospitals (from least-cost to best-facility to most-optimal), helping patients take the treatment, post-treatment rehabilitation
Complementary treatment: Helping with side effects & symptoms management through scientific evidence-based protocols involving Medical Cannabis, Ayurveda, Anti cancer diet, Oxygen therapy, etc
Few important resources:
You can find few important links here - this includes list of oncologists, dietitian connect, medical cannabis, AI-based treatment report, cancer survivor stories: https://linktr.ee/zenoncoio
We understand that it is very easy to get lost in this whole new world of cancer. Our dedicated team of cancer coaches shall be your constant companions to help you navigate through this entire cancer journey and shall provide all the comfort that you may need. You can connect with our cancer coaches by calling or sending WhatsApp at +919930709000.
https://zenonco.io/
Social Media Links:
Facebook: https://www.facebook.com/ZenOnco.ioOfficial
Instagram: https://www.instagram.com/zenoncoio
LinkedIn: https://in.linkedin.com/company/zenonco-io
Twitter: https://twitter.com/ZenOncoIO
YouTube:
https://www.youtube.com/c/ZenOncoIo
10 most reliable cro’s to watch in 2021insightscare
We featured a few trustworthy CROs making a difference in the health space in our latest edition of Insights Care - 10 Most Reliable CROs to Watch in 2021.
Let us share with you our successes, impacts and performance over the past year. The Innovation Agency is proud to bring you our Annual Report for 2015/16.
Ahead of the marcus evans Evolution Summit 2023 and the Evolution Europe Summit 2023, read here an interview with Alexander Fetkovsky discussing the gaps in the clinical trial supply chain.
Liquid Biopsy Market PPT 2023: Size, Growth, Demand and Forecast till 2028IMARC Group
The global liquid biopsy market size reached US$ 1.8 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 4.3 Billion by 2028, exhibiting a growth rate (CAGR) of 15.3% during 2023-2028.
More Info:- https://www.imarcgroup.com/liquid-biopsy-market
Endoscope Reprocessing Market by Product Type, Distribution Channel, End User...IMARC Group
The global endoscope reprocessing market size reached US$ 2.0 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 3.2 Billion by 2028, exhibiting a growth rate (CAGR) of 7.6% during 2023-2028.
More Info:- https://www.imarcgroup.com/endoscope-reprocessing-market
Oncology Startups 2017, is the first unique attempt to provide highly precise and updated information on newly established cancer drug developing companies and enables their early identification.
The Report illuminates Top 500 cancer drug developers established during 2010-2016, and without any doubt is one of the world’s largest focused data coverage on Active Drug Developers working with numerous methodologies to target cancer.
For Details https://omicsx.com/reports/cancer/oncology-startups-2017/
Companion Diagnostics Market PPT: Growth, Outlook, Demand, Keyplayer Analysis...IMARC Group
The global companion diagnostics market size reached US$ 5.0 Billion in 2021. Looking forward, IMARC Group expects the market to reach US$ 11.7 Billion by 2027, exhibiting a growth rate (CAGR) of 14.78% during 2022-2027.
More Info:- https://www.imarcgroup.com/companion-diagnostics-market
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
CHI's 10th Annual Next Generation Dx Summit, August 20-24, 2018, Washington, DCJames Prudhomme
Next Generation Dx Summit has grown to more than 1,000 international diagnostic professionals working in the field and offers unparalleled insight from the comprehensive programming and networking with key opinion leaders in the industry. The event is unique in the marketplace. This year the coverage spans cell- and cell-free biopsies, commercialization, reimbursement, biomarkers and companion diagnostics for immunotherapy, point-of-care testing, infectious disease, microfluidics and precision medicine. Now in its tenth year, Next Generation Dx Summit is a must-attend event with complete coverage of the most timely and important issues for the industry.
Cancer Tumor Profiling Market Growth, Demand and Challenges of the Key Indust...IMARC Group
The global cancer tumor profiling market reached a value of US$ 9.38 Billion in 2021. Looking forward, IMARC Group expects the market to reach a value of US$ 18.22 Billion by 2027 exhibiting a growth rate (CAGR) of 11.20% during 2022-2027.
More Info:- https://www.imarcgroup.com/cancer-tumor-profiling-market
Latest investor deck for Avatr's seed campaign.
Our technology called Avatr is a unique AI technology that pools multiple sources of data to create a digital representation of a patient.
AVATR keeps the patient permanently connected with their doctor in real time, and delivers timely patient insights as and when the doctor needs it.
We have launched our MVP in Singapore, and are raising £300k for 10% equity
The Pharma Research 2018 Conference includes a wide range of Keynote presentations, Oral talks, Poster presentations, Symposia, Workshops, Exhibitions and Career development programs. The conference invites delegates from Leading Universities, Pharmaceutical companies, Formulation Scientists, Medical Devices, Researchers, Health care professionals, students, business delegates and Young researchers across the globe providing a better podium, interconnecting the latest research, technological developments in the arena as well as therapeutic aspects. Participating at Pharma Research 2018 International conference will be an excellent opportunity to meet eminent personalities in the fields of pharmaceutics and learn about the latest technological advancements.
Companyprofilesandconferences.com glad to promote a new report on "Digna Biotech, S.L. - Product Pipeline Analysis" which are focuses on the development and commercialization of robust clinical therapeutic candidates through partnerships with pharmaceutical companies.
HIV Drugs Market Competitive Research And Precise Outlook 2023 To 2030subishsam
The research firm Contrive Datum Insights has just recently added to its database a report with the heading global HIV Drugs Market .Both primary and secondary research methodologies have been utilised in order to conduct an analysis of the worldwide HIV Drugs Market . In order to provide a comprehensive comprehension of the topic at hand, it has been summed up using appropriate and accurate market insights. According to Contrive Datum Insights, this worldwide comprehensive report is broken up into several categories in order to present the data in a way that is understandable, succinct,
Overview of the Health B2B2C Ecosystem; Use Social Media as a Market Focus Tool; Measure Your Performance; American Health Insurance Reality; Lack of Doctor Relationship; PR is the New Primary Care Facilitator; For Health Marketers – End-users Matter; Innovation drives healthcare advances; Ways to Improve Health and Make Money; Medicine Is a Team Sport; Big Data- Allowing Individual Patients to Leverage The Many; Some Examples of What Works- Equashield, EarlySense, MD Anderson, LifePoint; 3D Systems; American Association for Cancer Research,
2014 Overview of significant trends in the life sciences (Biotechnology, Pharmaceutical, Device and Diagnostics) industry with Big Data in the Life Sciences featured articles.
ZenOnco.io :
"Saving lives from cancer"
We provide end-to-end care to cancer patients regarding both medical (surgery, chemo, radiation, advanced treatment) as well as complementary treatment (eg, Anti Cancer Diet, Medical Cannabis, Ayurveda, etc) to improve their quality of life and increase chances of cure.
We educate and empower patients and their caregivers, plan their treatment roadmap, standardize service providers, facilitate treatment for last-mile care delivery, connect with other survivors, and do regular follow-ups. We are leveraging technology to do this in a scalable manner. For instance, we were recognized at ESMO for launching the World’s first tool to generate free directional Integrative Oncology treatment reports (ZIOPAR). We have also recently launched a community platform to connect cancer patients, survivors & caregivers (akin to Quora for Integrative Oncology).
The cancer journey itself is long and complicated - we aspire to be a constant companion throughout this journey for any need and requirement to extend life and improve quality of life. We help with:
Medical treatment: Identifying which oncologist to meet, validating treatment opinions, getting high-quality affordable diagnostic tests, searching for best available hospitals (from least-cost to best-facility to most-optimal), helping patients take the treatment, post-treatment rehabilitation
Complementary treatment: Helping with side effects & symptoms management through scientific evidence-based protocols involving Medical Cannabis, Ayurveda, Anti cancer diet, Oxygen therapy, etc
Few important resources:
You can find few important links here - this includes list of oncologists, dietitian connect, medical cannabis, AI-based treatment report, cancer survivor stories: https://linktr.ee/zenoncoio
We understand that it is very easy to get lost in this whole new world of cancer. Our dedicated team of cancer coaches shall be your constant companions to help you navigate through this entire cancer journey and shall provide all the comfort that you may need. You can connect with our cancer coaches by calling or sending WhatsApp at +919930709000.
https://zenonco.io/
Social Media Links:
Facebook: https://www.facebook.com/ZenOnco.ioOfficial
Instagram: https://www.instagram.com/zenoncoio
LinkedIn: https://in.linkedin.com/company/zenonco-io
Twitter: https://twitter.com/ZenOncoIO
YouTube:
https://www.youtube.com/c/ZenOncoIo
10 most reliable cro’s to watch in 2021insightscare
We featured a few trustworthy CROs making a difference in the health space in our latest edition of Insights Care - 10 Most Reliable CROs to Watch in 2021.
Let us share with you our successes, impacts and performance over the past year. The Innovation Agency is proud to bring you our Annual Report for 2015/16.
Ahead of the marcus evans Evolution Summit 2023 and the Evolution Europe Summit 2023, read here an interview with Alexander Fetkovsky discussing the gaps in the clinical trial supply chain.
Liquid Biopsy Market PPT 2023: Size, Growth, Demand and Forecast till 2028IMARC Group
The global liquid biopsy market size reached US$ 1.8 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 4.3 Billion by 2028, exhibiting a growth rate (CAGR) of 15.3% during 2023-2028.
More Info:- https://www.imarcgroup.com/liquid-biopsy-market
Endoscope Reprocessing Market by Product Type, Distribution Channel, End User...IMARC Group
The global endoscope reprocessing market size reached US$ 2.0 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 3.2 Billion by 2028, exhibiting a growth rate (CAGR) of 7.6% during 2023-2028.
More Info:- https://www.imarcgroup.com/endoscope-reprocessing-market
Oncology Startups 2017, is the first unique attempt to provide highly precise and updated information on newly established cancer drug developing companies and enables their early identification.
The Report illuminates Top 500 cancer drug developers established during 2010-2016, and without any doubt is one of the world’s largest focused data coverage on Active Drug Developers working with numerous methodologies to target cancer.
For Details https://omicsx.com/reports/cancer/oncology-startups-2017/
Companion Diagnostics Market PPT: Growth, Outlook, Demand, Keyplayer Analysis...IMARC Group
The global companion diagnostics market size reached US$ 5.0 Billion in 2021. Looking forward, IMARC Group expects the market to reach US$ 11.7 Billion by 2027, exhibiting a growth rate (CAGR) of 14.78% during 2022-2027.
More Info:- https://www.imarcgroup.com/companion-diagnostics-market
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
2. 2
Page 3 About Sunvalley Communication
Page 4 Media Properties
Page 5 – 8 ADC Review, Journal of Antibody-drug Conjugates
Page 9 ADC Directory, A Guide to the World of Antibody-drug Conjugate
Page 10 - 12 OncoZine, The International Oncology Network
Page 13 – 15 The OncoZine Brief (Radio)
Page 16 Oncology Directory
Page 17 Event Coverage
Page 18 Specifications
Headquarters:
Sunvalley Communication, LLC
4960 S. Gilbert Road, Suite 1-286
Chandler, AZ 85249
Phone +1 480 626 7218
Fax +1 480 452 1195
sunvalleycommunication.com
Advertising & Sponsorship Contact:
Shaun Mehr
Associate Publisher
+1 949 923 1660
s.mehr@sunvalleycommunication.com
3. About Sunvalley Communication
We Are Strategic Medical Communication
Sunvalley Communication is a global
strategic medical communications agency.
We provide innovative, customized and
effective solutions for pharmaceutical,
medical device and diagnostic companies
active in oncology, hematology, cancer
supportive care and neurology.
Our competencies and expertise are unique
to the industry, making us a trusted partner
with a dedicated, multidisciplinary teams that
work with you from strategy development and
content development, to flawless execution.
3
• Dynamic team of healthcare
education and communication
specialists.
• Develop engaging educational
content and programs for global,
regional and single market
audiences.
• Specialize in translating complex
scientific data into compelling
content targeting scientists,
researchers, clinicians and
physicians.
• We offer strategy, content
development and publication
planning.
• Publishers of ADC Review,
OncoZine, ADC Directory and
Oncology Directory.
4. Media Properties
ADC Review, Journal of Antibody-drug Conjugates
Peer reviewed journal targeting an international audience of over 17,000 industry professionals engaged in the research,
development, regulation and manufacturing of antibody-drug conjugates.
OncoZine, The International Oncology Network
Peer reviewed journal targeting an international audience of over 5,000 physicians, clinicians, patients and advocates focused on
the practice of oncology and hematology in the treatment of all forms of cancer.
The OncoZine Brief
International radio program and podcast providing the latest news and information on cancer, cancer diagnosis and treatment with
an average audience of 400,000 listeners, 90% of which are between the ages of 25-65. Distribution channels include UK Health
Radio, PRX, KNFX 1100 AM Radio (Phoenix, AZ) and iTunes, plus event / annual meeting coverage of industry events AACR,
ASCO and ASH.
ADC Directory, A Guide to the World of Antibody-drug Conjugates
A companion to the ADC Review, the ADC Directory provides a seamless exchange of information between businesses and
professionals focused on the research, development and manufacture of antibody-drug conjugates. Members of the ADC Directory
can share reviews, articles, videos, events products, career opportunities and more.
Oncology Directory
A companion to OncoZine, the Oncology Directory provides a member drive resource for medical professionals, clinicians, patients
and their advocates on the topic of oncology and hematology. Members of the Oncology Directory can share reviews, articles,
videos, events products, career opportunities and more.
4
5. About
ADC Review, Journal of Antibody-drug Conjugates (ISSN 2327-0152) is
an international peer-reviewed journal.
ADC Review, launched in 2013, is designed to serve the needs of a
diverse community of individuals including academia, life sciences,
pharma, research (basic, translational and clinical), clinicians,
physicians, regulatory, government authorities and representatives from
payers to policy makers.
The content includes peer reviewed research, commentaries, news
features, discussions, editorials and blogs on topics relevant to a broad
international readership. Additional resources include ADC University, a
knowledge center offering the latest and most relevant information about
Antibody-drug Conjugates, Small Molecule Drug Conjugates (SMDC),
and Engineered Antibody Fragments.
The purpose of ADC Review is a platform where all stakeholders can
access easy to understand and useful information about ADCs.
5
New Site
6. Editorial Calendar
Manuscript Guidelines & Editorial Calendar
January - March 2019
q Development of the Next Generation of ADCs
q Challenges in Scaling Up Process Development in ADCs
q Payloads with differentiated mechanism of action
q Analytical Development and QC in ADC Manufacturing
April - June 2019
q How to maximize the clinical therapeutics window of ADCs
q Project management, cGMP production, technology transfer and
outsourcing in ADC manufacturing
q Minimizing off-targeted toxicity of Chemistry, Manufacture and
Control (CMC) design and IND submission
July – September 2019
q Overcoming challenges in conjugation manufacturing
q How to reduce toxicities and enhance tumor antigen targeting
q Maximizing the clinical potential of ADCs • Regulatory
expectations in ADCs
October – December 2019
q Analytical development and QC in ADC manufacturing
q Analytical method development and method validation
q Comparison of ADCs with current stand of care
6
7. Audience
Audience: 17,121 Readers
Target Audience:
q Large Drug Development (Pharma / Biotech)
q Small & Medium Drug Development
q Equipment Manufacturers
q Contract Clinical Research Organizations
q Physicians & Clinicians
q Contract Development & Manufacturing
Organizations
q Regulatory & Government Agencies
q Platform Technology
q Academia
7
1. USA
2. Netherlands
3. UK
4. India
5. Germany
6. Japan
7. Canada
8. France
9. South Korea
10.China
11.Italy
12.Taiwan
13.Switzerland
14.Australia
15.Spain
16.Ireland
17.Sweden
18.Russia
19.Poland
20.Singapore
21.Belgium
22.Hong Kong
23.Brazil
24.Denmark
Audience Location (Ranked)
8. Programs
Banner Advertising:
300 x 250 / Run of Site @ $1,650 per month
Large Leaderboard / 970 x 250 – non-animated / rotate per impression / ROS @ $1,850
Poster Talk Video: $2,500 per video
Includes recording, video production and hosting for 1 year.
Native Ad Post: $1,650 per post
Up to 500 words, ideal for promoting lead generation resource like white papers. Includes monthly lead reporting 1 year.
Sponsored Article: $4,500 per article
Up to 3,000 word sponsored editorial, including interview, writing, layout and design, with images provided by advertiser.
Custom Email Blast: $3,500 per email blast
Provide content in either word document or HTML and schedule mailing.
Lead Generation Webinar: $8,500 per webinar
Generate leads with a custom webinar, including moderator and weekly lead reports.
The Review Sponsor: Request Quote
ADC Drug Map Sponsorship: $1,500 per month
Recognition as sponsor, including banner ad, your logo and short description of your company.
Video Vine: $1,000 per video
Up to 60 second news brief formatted for social media news feeds, ideal for summarizing a press release.
Video Documentary and Publication Planning: Request Quote
8
9. ADC Directory
As an companion to ADC Review, we created ADC Directory
to provide our readers a comprehensive tool to discover new
resources in their pursuit to develop ADCs and our
advertisers a cost effective way to promote those resources.
We offer two levels of membership to serve needs of our
readers and our advertisers:
Professional Memberships are free and allow individuals to
create a profile to promote their expertise and share review.
Business Memberships allow companies to share their
expertise by posting articles, videos, podcasts, events,
promotions, products, jobs and internships. Businesses can
also generate leads when users request more information on
their profile.
9
Business Membership:
$2,970 per year / $275 per month /
$25 CPL
Get Listed Today!
Banner Ad Bundle: $1,200 per month
728 x 90 Top Leaderboard
300 x 250 Right Rail
728 x 90 Footer
10. About
Onco’Zine – The International Oncology Network (ISSN 21688-
5339) is published jointly by InPress Media Group and Sunvalley
Communication. Our online journal publishes a broad range of
topics and timely news updates focused on all oncology disciplines
and specialties from around the world. Onco’Zine is a sponsor-
supported, interactive online community for healthcare
professionals and other medical specialists involved in the
management and care of cancer patients.
With correspondents located throughout the United States, Canada
and Europe, we offer in-person specialized coverage of scientific
meetings and conferences. Our aim is to provide first-hand reports
and interviews with researchers, clinicians, industry executives and
government figures whose work and actions are shaping the
practice of oncology and hematology.
10
11. Audience
Audience: 2,962
Target Audience:
q Oncologists
q Hematologists
q Physicians & Clinicians
q Large Drug Development (Pharma /
Biotech)
q Small & Medium Drug Development
q Equipment Manufacturers
q Contract Clinical Research Organizations
q Contract Development & Manufacturing
Organizations
q Regulatory & Government Agencies
q Platform Technology
q Academia
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1. USA
2. France
3. Germany
4. India
5. Philippines
6. Italy
7. Brazil
8. United Kingdom
9. Canada
10. Peru
11. Japan
12. South Africa
Audience Location (Ranked)
12. Programs
Banner Advertising: $1,250 per month
Leaderboard (728 x 90), Square (250 x 250), Skyscraper (322 x 600)
Poster Talk Video: $2,500 per video
Includes recording, video production and hosting for 1 year.
Sponsored Article: $4,500 per article
Up to 3,000 word sponsored editorial, including interview, writing, layout and design, with images
provided by advertiser.
Custom Email Blast: $3,500 per email blast
Provide content in either word document or HTML and schedule mailing.
Lead Generation Webinar: $8,500 per webinar
Generate leads with a custom webinar, including moderator and weekly lead reports.
Video Vine: $1,000 per video
Up to 60 second news brief formatted for social media news feeds, ideal for summarizing a press
release.
Video Documentary and Publication Planning: Request Quote
12
13. The Onco’Zine Brief
The Onco’Zine Brief is an educational program developed for public
radio focused on cancer, from early diagnosis to treatment. Our aim
is to create engaging programming that delivers the latest scientific
and health related information for a broad audience of stakeholders
that range from patients and their advocates to physicians and
clinicians.
With both studio broadcasts and onsite coverage of leading cancer
events including the American Association for Cancer Research
(AACR), American Society of Clinical Research (ASCO), American
Society of Hematology (ASH) and CPhI Worldwide.
Our program is syndicated via PRX | Public Radio Exchange, UK
Health Radio, iHeart Radio, Independent Talk 1100 KFNX, iTunes,
Spreaker, Stitcher and Google Play. We also include bonus
distribution to the attendees of the events we cover.
13
14. Who’s Listening
q Syndicated in the United States and worldwide via
PRX, iHeart Radio, UK Health Radio, 1100 KFNX,
iTunes, Spreaker, Stitcher and Google Play
q Bonus distribution at leading industry events
including AACR, ASCO, ASH and CPhI.
q Over 5-6 million listeners per month
q Over 90% of our listeners are between the ages of
25-65 year
q Audience includes the full spectrum of stakeholders
from patients to medical professionals to clinicians.
14
Syndication Partners
Event Partners
15. Underwriting
We offer monthly, quarterly and annual underwritings
opportunities that include promotions consistent with
public (non-commercial) broadcasts. These include 15
second spot at opening, entry from break and closing of
each program. We produce a minimum of four
programs with an average audience of 5–6 million
listeners per month, plus bonus distribution during event
coverage with our event partners
Rates are as follows:
$ 3,800 per month
$ 9,900 per quarter
$ 18,600 semi-annually (6 months)
$ 36,000 annually (12 months)
15
16. Oncology Directory
As a companion to Onco’Zine, we created the Oncology Directory to
provide our readers a comprehensive tool to discover the latest
developments in cancer treatment, while offering medical professionals,
businesses, institutions and foundations the opportunity to share their
expertise.
We offer three levels of membership to serve needs of our readers and
our advertisers:
Basic Memberships offer a free option for patients and their
advocates to join the Oncology Directory.
Professional Memberships are ideal for medical professionals and
industry executives, offering the ability to generate leads and post up to
3 articles.
Business Memberships allow companies to share their expertise by
posting articles, videos, podcasts, events, promotions, products, jobs
and internships. Businesses can also generate leads when users
request more information on their profile
16
Business Membership:
$249 month / $2,499 year/ $25 CPL
Get Listed Today!
Banner Ad Bundle: $1,200 per month
728 x 90 Top Leaderboard
300 x 250 Right Rail
728 x 90 Footer
17. Event Coverage
17
March 2019
q 15th Annual Symposium on Pancreatic Cancer, Los Angeles,
CA
q 9th Annual World ADC, London, United Kingdom
q 72nd Annual Society of Surgical Oncology Annual
Symposium, San Diego, CA
q American Association for Cancer Research (AACR) Annual
Meeting, Atlanta, GA
April 2019
q ELCC 2019 – European Lung Cancer Conference, Geneva,
Switzerland
q CPhI North America, Chicago, IL
May 2019
q ESMO Breast Cancer, Berlin, Germany
q EACR-ESMO Joint Conference on Liquid Biopsies,
Bergamo, Italy
q American Society of Clinical Oncology Annual Meeting
(ASCO), Chicago, IL
June 2019
q 24th Congress of EHA (European Hematology Association),
Amsterdam, The Netherlands
q 7th International Conference on Advances in Hematology
and Oncology, ICAHO19, Seattle, WA
July 2019
q ESMO 21st World Congress on Gastrointestinal Cancer,
Barcelona, Spain
September 2019
q IASLC 2019 World Conference on Lung Cancer, Barcelona,
Spain
q 2019 American Society for Radiation Oncology (ASTRO),
Chicago, IL
q European Society of Medical Oncology ESMO 2019
Congress, Barcelona, Spain
October 2019
q 10th Annual World ADC, San Diego, CA
q 16th Society for Integrative Oncology (SIO) 16th International
Conference, New York, NY
q International Society of Pediatric Oncology (SIOP), Lyon,
France
November 2019
q CPhI Worldwide, Frankfurt, Germany
q MAP 2019 – Molecular Analysis for Personalized Therapy,
London, UK
q 11th European Multidisciplinary Congress on Urological
Cancers (EMUC), Vienna, Austria
q 5th ESMO Asia Congress, Singapore
December 2019
q ESMO Immuno-Oncology Congress 2019, Geneva,
Switzerland
q 61st ASH Annual Meeting & Exposition, Orlando, FL
q 42nd Annual SABCS, San Antonio, TX
18. Specifications
18
Site Name Dimensions Max Size
Max Animation
Length
File Format
ADC Review Top Leaderboard 600 x 90 200k 8 seconds GIF or Animated GIF
ADC Review Right Rail 316 x 117 200k 8 seconds
GIF or Animated GIF
ADC Review
(Available April 2019)
Top Large
Leaderboard
970 x 250 250k No Animation GIF
OncoZine
ADC Directory
Oncology Directory
Top Leaderboard 728 x 90 200k 8 seconds
GIF or Animated GIF
OncoZine Right Rail, Skyscraper 322 x 600 250k 8 seconds GIF or Animated GIF
OncoZine
ADC Directory
Oncology Directory
Right Rail, Square 250 x 250 200k 8 seconds GIF or Animated GIF
ADC Directory
Oncology Directory
Footer 970 x 90 200k 8 seconds GIF or Animated GIF
For questions or to submit materials, please contact:
Shaun Mehr | +1 949 923 1660
s.mehr@sunvalleycommunication.com