in	
  Silicon	
  Valley
NASA’s Space Technology Program - Development Approach


                          Idea
                                          Idea

                                   Idea                                                                                                             Infusion
                                                                Idea
                                                                                                                                                    Opportunities
                                                 Idea                                                  Possible
                                                                                                       Solution                                     for NASA
                                                                                                                                                    Mission
  Visions of the Future




                                   Idea                        Idea                         Possible               Possible
                                                                                            Solution               Solution




                                                                         Does it WORK?




                                                                                                                              Is it Flight Ready?
                                                                                                       Possible
                                                                                                                                                    Directorates,
                                                 Idea
                                                                                                       Solution                                     Other Govt.
                                                                Idea
                                   Idea                                                                                                             Agencies, and
                                                        Idea                                                                                        Industry
                                 Idea
 Industry
 Academia
 Gov’t




                                                                                                                  Mature crosscutting capabilities
 Creative ideas regarding                                       Prove feasibility of novel, early-stage
                                                                                                                  that advance multiple future space
 future NASA systems or                                         ideas with potential to revolutionize a
                                                                                                                  missions to flight readiness status
 solutions to national needs.                                   future NASA mission and/or fulfill
                                                                national need.


                                                                                                                                                                    8
TECHNOLOGY & INNOVATION DEFINITION FLOWDOWN


Na$onal	
  Innova$on	
  Strategy	
  


    NASA	
  Strategic	
  Goals	
  


            NASA	
  Grand	
  Challenges	
  


                      Space	
  Technology	
  Roadmap(s)	
  

                                                   IPTs	
          Proposals,	
  
    ARC	
  Tech	
              Strategic	
  
                                               (Tech	
  Wrkg	
      Projects,	
  
     Areas	
                  Ini2a2ves	
  
                                                  Grps)	
           Products	
  
NASA’s Space Technology Program




OFFICE OF THE CHIEF TECHNOLOGIST       www.nasa.gov/oct      4	
  
Developing systems to monitor the health and
performance of NASA personnel and the functional
      status of the systems that support them
Physiological	
  Monitoring	
  of	
  Astronauts	
  




                                                      Biotelemeter implanted in amimals, or
                                                      ingested by/attached to astronauts!
 TriSponder!                                          senses Body Temperature,!
 quickly displays!                                    Blood Pressure, Blood pH,!
 Health Status.                                       and Heart Rate.




                                                                                 Transponder relays
                                                                                 biotelemeter signal !
                                                                                 to other monitoring
                                                          ECG
                                                                                 devices.
                                                                     HR 87
                                                          Temp 36.8C
                                                                     pH 7.35
                                                           BP 125/80


Physiological!                                                                    Laptop!
Signal Conditioner!                                                               monitors and!
(PSC) acquires ECG,!                                                              analyzes!
EEG, EMG, and EOG !                                                               Physiological!
(and other bio-                                                                   Parameters.!
parameters of interest.!
MONITORING                                                           Output Module
Temperature       Biosensors DEVICE                                                               (FHSS
  Sensor                                                                                          Transmitter,
                  Respiration                                                                     Datalogger,
                                                                                                  Display, etc.)
                   Ingest                                                               Battery
                   able
                   Sensor                                                            Core Module
                     Pulse
                     Oximeter                                                        Transceiver Modules

                                                               Commands
   Monitoring
   Device



                ECG                                            Data & Status
                Electrodes

                             Temp.               ECG               Bio

                                                   ECG                   Bio
                                Temp.

                                                       ECG                     Bio

                        WIRELESS                                                                          Pulse Oximeter
                                                                                                          (Blood Gases)
                        SENSORS
                      (Transducer + Signal
                    Conditioner + Transceiver)     Pressure, Core Temp.    pH, Calcium, Glucose,...
Fetal Biotelemetry System
Distributed Environmental and Physiological Monitoring

HMD                         Environmental
(TBD)           SpO2        Monitor (MPM)
                (Nonin)        •  Temp.
                               •  Pressure
                               •  O2
                               •  CO2
         ECG
        (QRS)
                              Head Mount
                              Display
                             Physiological
                             Monitor (iPAQ)
                               •  Body Temp.
        iPAQ                   •  Blood Pressure
                               •  SpO2
                               •  Respiration
                    RF         •  Heart Rate / ECG
                 (Proxim)      •  Activity




                                                              Space Station / Shuttle Scenario



                                                                     Server
                                                                       •  Data Display
                             Server                                    •  Data Distribution
Dave Williams                                                          •  Data Analysis
                            (Laptop)
Demonstration
PEM	

                             Personal	

                              Status	

               PPM	

                               Comm	

                             Monitor	

                              (PSM)	

               PCM	




                         Decision	

            Data	

     Controller	

       Assistant	

        Management	





       PSM: Personal Status Monitor 	

	

                              PSM: Personal Status Monitor
                                                                      PA: PreAmplifier               S: Sensor
     PPM: Personal Physiological Monitor      	

              BT: BlueTooth    USB: Universal Systems Buss
	

 PEM: Personal Environmental Monitor      	

                                A: Actuator
                                                                      TM: Telemetry Transmitter Module
      PCM: Personal Clinical Monitor 	

                           FHSS: Freq. Hopping Spread Spectrum
                                                                               IR: InfraRed
                                                              Mem: Memory             TMRx: Telemetry Reveiver
Space Station Intranet
                                                                                                   Prior System: Smart Health
                                          Optional link to
                                             Intranet
                                                                              Access
                                                                               Point
                                                                                                   Care Management System
                                iPAQ SwitchBoard                                                                  (SHMS)
                                              Wireless LAN
                                             (RL2, 802.11b,
  iPAQ Client                                  Bluetooth)
                                                                               Laptop                Various Data Sources supported
                                                                               Client                 (Physiological and Environmental
                                                                                                      Sensors, Video (wired/wireless), GPS)
                                                                                                     Various Client Devices supported
                                                                          Laptop Video                (Pocket PCs, HMDs, Laptops, PCs)
                                                                             Server                  Local ad-hoc Networking using iPAQ-
                                                                                                      SwitchBoard or Laptop-SwitchBoard
                                                                                                     Ad-hoc Network can be connected to
                                                                                                      Intranet as soon as Access Point is in
                                                                                                      range, as well as Internet
iPAQ Client with ECG/                                                                                Compatible with most Wireless LAN
   Resp. Monitor                                                                                      Technologies (RangeLAN2, 802.11b,
                                                                       iPAQ Client                    Bluetooth)
                                                                         with HMD                    Low Bandwidth Requirement (128-kbps
     iPAQ Client with
                                  GPS-iPAQ
      Pulse Oximeter                                                                                  S-Band compatible)
                                                              Environmental Monitor                  Modular, Flexible, Reliable, and Secure



          Downlink
          (S-Band or Ku-Band)                                                           Internet
                                                                                                                             Client
                                                   Wireless
                                                    Video
                                                   Server                                               Video
                                                              Access                                    Server
                                                               Point
                                                                                                      Stanford University,
                                      JSC Intranet                                                      NASA Ames, .
                                                                         iPAQ Client
LIFEGUARD

                          LifeGuard Monitoring System - Overview


                                             Nexan ECG/Repsiration Sensor
Nexan           Physiological Logger with
Sensor          Streaming Capabilities
                (CPOD)
                                                                                      Nonin Pulse
               BP
               Cuff                                                                   Oximeter (SpO2)


   BP
   Monitor
                  Nonin
                  SpO2



                                                                                Accutracker II Blood
                                                                                Pressure Monitor
                                                                                (flight qualified)
                                               CPOD Data Logger

                                            Base Station
   CPOD logs data.                                                          Base Station
   Download via                                            or
   RS-232 or wireless:
Non-NASA
Application of SHMS:
Homeland Security
and Defense




                       NASA DART
                       Participation
Test, Applications, and Integration	

Testing, testing, and more testing




        INMARSAT	

        SATELLITE
EVA and IVA Physiological Monitoring	

•  Keep crew safe, healthy, and performing optimally	

•  Prevent, recognize, diagnose, and treat illness and injury	


  IVA – medical exams, exercise, research, fitness evaluations
EVA and IVA Physiological Monitoring Requirements	

                        Current	
  HSIR	
  requirements	
  
                                                                                                         Requirements	
  (Medical	
  Opera$ons)	
                                Requirements	
  (Research)	
  
 TABLE 3.10.5.1-1 - MEASUREMENT OF PHYSIOLOGICAL PARAMETERS
                                     Unpressurized and
                                          Ventilation            Pressurized             Lunar Surface    Monitoring	
  ECG	
       Minimum	
  of	
  2	
                  Holter	
  Monitor/          Minimum	
  of	
  2	
  
          Suit Parameter                                                                                                            independent	
  
                                           Pressure               Operations              Operations                                                                      ECG	
                       independent	
  
                                                                                                                                    channels	
  for	
  up	
  to	
                                     channels	
  for	
  up	
  
                                         Operations                                                                                 48-­‐hours	
                                                      to	
  48-­‐hours	
  
Breathing gas flow rate (real-time)           X                        X                       X
                                                                                                                                                                          Diagnos$c	
  ECG	
          12-­‐lead	
  ECG	
  for	
  a	
  
ppO 2                                         X                        X                                  Diagnos$c	
  ECG	
        12-­‐lead	
  for	
  both	
                                        minimum	
  of	
  10	
  
Oxygen consumption rate (real-                                                                                                      10-­‐30	
  second	
                                               sequen$al	
  
                                                                                               X                                    "snapshot"	
  mode,	
  
time)                                                                                                                                                                                                 minutes	
  that	
  
                                                                                                                                    and	
  10-­‐minute	
                                              employs	
  8	
  
Suit pressure (real-time)                                              X                       X                                    "full	
  disclosure”	
                                            independent	
  
ppCO2 (real-time)                                                      X                       X                                    mode	
                                                            channels	
  (using	
  a	
  
                                                                                                                                                                                                      standard	
  10-­‐
Consumables (power, oxygen,                                                                                                                                                                           electrode	
  
                                              X                        X                       X
water, etc., real-time)                                                                                                                                                                               configura$on)	
  
                                                                                                          Heart	
  Rate	
           0-­‐250	
  beats	
  per	
  
Thermal loading to each EVA                                                                                                         minute	
                              Cardiac	
  Output	
  	
     Con$nuous	
  
                                                                                               X
crewmember (calculated)                                                                                   Respiratory	
  Rate	
     0-­‐150	
  breaths	
  per	
                                       cardiac	
  output	
  for	
  
Heart rate (real-time)                                                 X                       X                                    minute	
  	
                                                      up	
  to	
  24	
  hours	
  

Metabolic Rate (calculated)                                                                    X                                                                          Con$nuous	
  Blood	
        Con$nuous	
  Blood	
  
                                                                                                          Body	
  Temperature	
     84.0	
  °F	
  to	
  108.0	
  °F	
     Pressure	
  	
              Pressure	
  for	
  up	
  to	
  
Radiation Exposure Data                                                                        X                                                                                                      24	
  hours	
  
Notes:                                                                                                    Blood	
  Pressure	
       Systolic	
  60-­‐250	
  
                                                                                                                                    mmHg	
                                Body	
                      84.0	
  °F	
  to	
  108.0	
  
         For suited operations, measure the parameters in gray on an individual suit basis.                                                                               Temperature	
               °F	
  
                                                                                                                                    Diastolic	
  30-­‐160	
  
         For a single gas environment, ppO2 and total suit pressure are identical values and do not                                 mmHg	
  
        require separate sensors. Otherwise
                                                                                                          Blood	
  Oxygen	
         70-­‐100%	
  	
  
                                                                                                          Satura$on	
  
The Challenges                        EVA HR
•    Maximize the comfort, ease of use,
     reliability, and accuracy 	

                                               Monitoring
•    Minimize the equipment's mass, volume,
                                              Requirements	

     power, and time for set-up and use 	


 Apollo                     Shuttle
Sensors	

                  Sensors	





      Space
      Station
     Hardware
Market	
  Survey/Lessons	
  Learned	
  
•   Many systems rely on perspiration/moisture
•   Nearby EMI can totally disrupt biomedical signals
•   Not all systems have local display, ensure data is actually recording
•   Have no buttons on the device that can be accidentally toggled
•   The sensor is only the front end - many other factors contribute to final
     signal quality
•   Motion artifact remains one of key problems
•   Wireless an option - but many technical issues remain
•   Some devices need attention to keeping them in place on the body
•   Three considerations for sensor contact to skin
•   Placement of sensors sometimes key
•   Pick a financially viable company
•   Get agreement on the definition of easy to don/doff
Future Space Medicine Health Care
•  Portability and application of
   nano-technology
•  Minimally/non-invasive,
   efficient diagnostic systems
   capable of detecting
   abnormal human function
   across all body systems
•  Health care approaches
   capable of therapeutic
   intervention for a wide range
   of pathological and trauma
   scenarios
BAN / Wireless monitoring systems
    problems for acceptance



                       Business     Applications



                                  BAN
                      Standards     Technology
Conclusion	

Continue to improve the human to biomedical sensor interface!
Business      Applications



            BAN
Standards     Technology

Lessons Learned from Space Technology Development

  • 1.
  • 2.
    NASA’s Space TechnologyProgram - Development Approach Idea Idea Idea Infusion Idea Opportunities Idea Possible Solution for NASA Mission Visions of the Future Idea Idea Possible Possible Solution Solution Does it WORK? Is it Flight Ready? Possible Directorates, Idea Solution Other Govt. Idea Idea Agencies, and Idea Industry Idea Industry Academia Gov’t Mature crosscutting capabilities Creative ideas regarding Prove feasibility of novel, early-stage that advance multiple future space future NASA systems or ideas with potential to revolutionize a missions to flight readiness status solutions to national needs. future NASA mission and/or fulfill national need. 8
  • 3.
    TECHNOLOGY & INNOVATIONDEFINITION FLOWDOWN Na$onal  Innova$on  Strategy   NASA  Strategic  Goals   NASA  Grand  Challenges   Space  Technology  Roadmap(s)   IPTs   Proposals,   ARC  Tech   Strategic   (Tech  Wrkg   Projects,   Areas   Ini2a2ves   Grps)   Products  
  • 4.
    NASA’s Space TechnologyProgram OFFICE OF THE CHIEF TECHNOLOGIST www.nasa.gov/oct 4  
  • 6.
    Developing systems tomonitor the health and performance of NASA personnel and the functional status of the systems that support them
  • 7.
    Physiological  Monitoring  of  Astronauts   Biotelemeter implanted in amimals, or ingested by/attached to astronauts! TriSponder! senses Body Temperature,! quickly displays! Blood Pressure, Blood pH,! Health Status. and Heart Rate. Transponder relays biotelemeter signal ! to other monitoring ECG devices. HR 87 Temp 36.8C pH 7.35 BP 125/80 Physiological! Laptop! Signal Conditioner! monitors and! (PSC) acquires ECG,! analyzes! EEG, EMG, and EOG ! Physiological! (and other bio- Parameters.! parameters of interest.!
  • 8.
    MONITORING Output Module Temperature Biosensors DEVICE (FHSS Sensor Transmitter, Respiration Datalogger, Display, etc.) Ingest Battery able Sensor Core Module Pulse Oximeter Transceiver Modules Commands Monitoring Device ECG Data & Status Electrodes Temp. ECG Bio ECG Bio Temp. ECG Bio WIRELESS Pulse Oximeter (Blood Gases) SENSORS (Transducer + Signal Conditioner + Transceiver) Pressure, Core Temp. pH, Calcium, Glucose,...
  • 9.
  • 10.
    Distributed Environmental andPhysiological Monitoring HMD Environmental (TBD) SpO2 Monitor (MPM) (Nonin) •  Temp. •  Pressure •  O2 •  CO2 ECG (QRS) Head Mount Display Physiological Monitor (iPAQ) •  Body Temp. iPAQ •  Blood Pressure •  SpO2 •  Respiration RF •  Heart Rate / ECG (Proxim) •  Activity Space Station / Shuttle Scenario Server •  Data Display Server •  Data Distribution Dave Williams •  Data Analysis (Laptop) Demonstration
  • 11.
    PEM Personal Status PPM Comm Monitor (PSM) PCM Decision Data Controller Assistant Management PSM: Personal Status Monitor PSM: Personal Status Monitor PA: PreAmplifier S: Sensor PPM: Personal Physiological Monitor BT: BlueTooth USB: Universal Systems Buss PEM: Personal Environmental Monitor A: Actuator TM: Telemetry Transmitter Module PCM: Personal Clinical Monitor FHSS: Freq. Hopping Spread Spectrum IR: InfraRed Mem: Memory TMRx: Telemetry Reveiver
  • 12.
    Space Station Intranet Prior System: Smart Health Optional link to Intranet Access Point Care Management System iPAQ SwitchBoard (SHMS) Wireless LAN (RL2, 802.11b, iPAQ Client Bluetooth) Laptop   Various Data Sources supported Client (Physiological and Environmental Sensors, Video (wired/wireless), GPS)   Various Client Devices supported Laptop Video (Pocket PCs, HMDs, Laptops, PCs) Server   Local ad-hoc Networking using iPAQ- SwitchBoard or Laptop-SwitchBoard   Ad-hoc Network can be connected to Intranet as soon as Access Point is in range, as well as Internet iPAQ Client with ECG/   Compatible with most Wireless LAN Resp. Monitor Technologies (RangeLAN2, 802.11b, iPAQ Client Bluetooth) with HMD   Low Bandwidth Requirement (128-kbps iPAQ Client with GPS-iPAQ Pulse Oximeter S-Band compatible) Environmental Monitor   Modular, Flexible, Reliable, and Secure Downlink (S-Band or Ku-Band) Internet Client Wireless Video Server Video Access Server Point Stanford University, JSC Intranet NASA Ames, . iPAQ Client
  • 13.
    LIFEGUARD LifeGuard Monitoring System - Overview Nexan ECG/Repsiration Sensor Nexan Physiological Logger with Sensor Streaming Capabilities (CPOD) Nonin Pulse BP Cuff Oximeter (SpO2) BP Monitor Nonin SpO2 Accutracker II Blood Pressure Monitor (flight qualified) CPOD Data Logger Base Station CPOD logs data. Base Station Download via or RS-232 or wireless:
  • 14.
    Non-NASA Application of SHMS: HomelandSecurity and Defense NASA DART Participation
  • 15.
    Test, Applications, andIntegration Testing, testing, and more testing INMARSAT SATELLITE
  • 20.
    EVA and IVAPhysiological Monitoring •  Keep crew safe, healthy, and performing optimally •  Prevent, recognize, diagnose, and treat illness and injury   IVA – medical exams, exercise, research, fitness evaluations
  • 21.
    EVA and IVAPhysiological Monitoring Requirements Current  HSIR  requirements   Requirements  (Medical  Opera$ons)   Requirements  (Research)   TABLE 3.10.5.1-1 - MEASUREMENT OF PHYSIOLOGICAL PARAMETERS Unpressurized and Ventilation Pressurized Lunar Surface Monitoring  ECG   Minimum  of  2   Holter  Monitor/ Minimum  of  2   Suit Parameter independent   Pressure Operations Operations ECG   independent   channels  for  up  to   channels  for  up   Operations 48-­‐hours   to  48-­‐hours   Breathing gas flow rate (real-time) X X X Diagnos$c  ECG   12-­‐lead  ECG  for  a   ppO 2 X X Diagnos$c  ECG   12-­‐lead  for  both   minimum  of  10   Oxygen consumption rate (real- 10-­‐30  second   sequen$al   X "snapshot"  mode,   time) minutes  that   and  10-­‐minute   employs  8   Suit pressure (real-time) X X "full  disclosure”   independent   ppCO2 (real-time) X X mode   channels  (using  a   standard  10-­‐ Consumables (power, oxygen, electrode   X X X water, etc., real-time) configura$on)   Heart  Rate   0-­‐250  beats  per   Thermal loading to each EVA minute   Cardiac  Output     Con$nuous   X crewmember (calculated) Respiratory  Rate   0-­‐150  breaths  per   cardiac  output  for   Heart rate (real-time) X X minute     up  to  24  hours   Metabolic Rate (calculated) X Con$nuous  Blood   Con$nuous  Blood   Body  Temperature   84.0  °F  to  108.0  °F   Pressure     Pressure  for  up  to   Radiation Exposure Data X 24  hours   Notes: Blood  Pressure   Systolic  60-­‐250   mmHg   Body   84.0  °F  to  108.0   For suited operations, measure the parameters in gray on an individual suit basis. Temperature   °F   Diastolic  30-­‐160   For a single gas environment, ppO2 and total suit pressure are identical values and do not mmHg   require separate sensors. Otherwise Blood  Oxygen   70-­‐100%     Satura$on  
  • 22.
    The Challenges EVA HR •  Maximize the comfort, ease of use, reliability, and accuracy Monitoring •  Minimize the equipment's mass, volume, Requirements power, and time for set-up and use Apollo Shuttle Sensors Sensors Space Station Hardware
  • 24.
    Market  Survey/Lessons  Learned   • Many systems rely on perspiration/moisture • Nearby EMI can totally disrupt biomedical signals • Not all systems have local display, ensure data is actually recording • Have no buttons on the device that can be accidentally toggled • The sensor is only the front end - many other factors contribute to final signal quality • Motion artifact remains one of key problems • Wireless an option - but many technical issues remain • Some devices need attention to keeping them in place on the body • Three considerations for sensor contact to skin • Placement of sensors sometimes key • Pick a financially viable company • Get agreement on the definition of easy to don/doff
  • 26.
    Future Space MedicineHealth Care •  Portability and application of nano-technology •  Minimally/non-invasive, efficient diagnostic systems capable of detecting abnormal human function across all body systems •  Health care approaches capable of therapeutic intervention for a wide range of pathological and trauma scenarios
  • 27.
    BAN / Wirelessmonitoring systems problems for acceptance Business Applications BAN Standards Technology
  • 28.
    Conclusion Continue to improvethe human to biomedical sensor interface!
  • 29.
    Business Applications BAN Standards Technology