We can make negative sentences with the verb "to be" by placing "not" after the verb. For example, the affirmative sentence "I am at home" becomes the negative sentence "I am not at home." We can also form yes/no questions using "be" verbs like "am", "are", and "is" and answering with "yes" or "no" plus the subject and verb, such as answering "No, I am not" to the question "Are you a teacher?". The document provides examples of filling in sentences with the correct "be" verbs.