Left heart failure
Definisi: Disfungsi ventrikel kiri yang menyebabkan insufisiensi pengaliran
darah ke seluruh organ vital tubuh
Etiologi:
• CAD
• Hipertensi
• Cardiomyopati
Patofisiologi: terjadi peningkatan tekanan kapiler pulmo  cairan berlebih
mengisi interstisial bronkovaskuler
Stage I : Redistribusi (12-18 mmHg)
• Patofis
↑ PCWP (pulmonary capillary wedge
pressure) mengakibatkan distensi
vessel yang telah mengalami perfusi
sebelumnya
• Adanya peningkatan resistensi
terhadap aliran ke base (arteri dan
vena ke lobus bawah dikompresi
oleh edema perivaskular)
peningkatan aliran ke apeks
(chepalisasi)
• Awalnya terjadi penyeimbangan aliran
darah kemudian redistribusi aliran dari
lobus bawah ke lobus atas
• Gambaran radiologi: cephalisasi,
Cardiomegaly, broad vascular pedicle
Stage II : Interstisial Oedema (18-25 mmHg)
- Patofis: bocornya cairan ke interstisial
peribronkial dan interlobular
- Gambaran radiologi:
Kerley B line
peribronchial cuffing
hazy contour vessel
penebalan fisura interlobular
Stage II : interstisial odem
• Penebalan septal lines karena
odem interstisial
• Subtle ground glass opacity in the
dependent part of the lungs (HU
difference of 100-150 between
the dependent and non-
dependent part of the lung).
• Bilateral pleural fluid
Stage III: alveolar odem (>25 mmHg)
Patofis: kebocoran lanjutan ke
interstisium, yang tidak bs
dikompensasi drainage limfatik 
sehingga bocor ke alveoli (alveolar
odem) dan ke ruang pleura (efusi
pleura)
Gambaran radiologi:
- Efusi pleura
- Air bronchogram
- Konsolidasi
- Bat-wing appearance
Stage III: alveolar odem
Pada rontgen dada dan pada
CT, edema bergantung pada
gravitasi dan perbedaan
densitas dapat diukur
Pulmonary odem
• 1. cardiogenic
• 2. non kardiogenik: ARDS
DD
• Diffuse pneumonia
• Massive aspiration
• Pulmonary hemmorhage
Pulmonary odem Left ventricular failure
In these settings, the hydrostatic pressure in the capillaries
exceeds the oncotic pressure and fluid is driven out of the
vasculature into the pulmonary interstitium and eventually
into the alveoli through the capillary endothelium and
alveolar epithelium.
• Chronic Left-Sided Heart Failure
• This condition is suggested by enlarged left-sided cardiac
chambers, with evidence of pulmonary venous hypertension
and with bilateral or a right-sided pleural effusion. (From 10% to
15% of patients with chronic left-sided heart failure have only a
left-sided pleural effusion, which, being unusual, should prompt
consideration of other causes of pleural disease.) Kerley B lines
are common.

Left heart failure.pptx

  • 1.
  • 2.
    Definisi: Disfungsi ventrikelkiri yang menyebabkan insufisiensi pengaliran darah ke seluruh organ vital tubuh Etiologi: • CAD • Hipertensi • Cardiomyopati Patofisiologi: terjadi peningkatan tekanan kapiler pulmo  cairan berlebih mengisi interstisial bronkovaskuler
  • 3.
    Stage I :Redistribusi (12-18 mmHg) • Patofis ↑ PCWP (pulmonary capillary wedge pressure) mengakibatkan distensi vessel yang telah mengalami perfusi sebelumnya • Adanya peningkatan resistensi terhadap aliran ke base (arteri dan vena ke lobus bawah dikompresi oleh edema perivaskular) peningkatan aliran ke apeks (chepalisasi) • Awalnya terjadi penyeimbangan aliran darah kemudian redistribusi aliran dari lobus bawah ke lobus atas • Gambaran radiologi: cephalisasi, Cardiomegaly, broad vascular pedicle
  • 4.
    Stage II :Interstisial Oedema (18-25 mmHg) - Patofis: bocornya cairan ke interstisial peribronkial dan interlobular - Gambaran radiologi: Kerley B line peribronchial cuffing hazy contour vessel penebalan fisura interlobular
  • 5.
    Stage II :interstisial odem
  • 6.
    • Penebalan septallines karena odem interstisial • Subtle ground glass opacity in the dependent part of the lungs (HU difference of 100-150 between the dependent and non- dependent part of the lung). • Bilateral pleural fluid
  • 7.
    Stage III: alveolarodem (>25 mmHg) Patofis: kebocoran lanjutan ke interstisium, yang tidak bs dikompensasi drainage limfatik  sehingga bocor ke alveoli (alveolar odem) dan ke ruang pleura (efusi pleura) Gambaran radiologi: - Efusi pleura - Air bronchogram - Konsolidasi - Bat-wing appearance
  • 8.
    Stage III: alveolarodem Pada rontgen dada dan pada CT, edema bergantung pada gravitasi dan perbedaan densitas dapat diukur
  • 9.
    Pulmonary odem • 1.cardiogenic • 2. non kardiogenik: ARDS DD • Diffuse pneumonia • Massive aspiration • Pulmonary hemmorhage
  • 10.
    Pulmonary odem Leftventricular failure In these settings, the hydrostatic pressure in the capillaries exceeds the oncotic pressure and fluid is driven out of the vasculature into the pulmonary interstitium and eventually into the alveoli through the capillary endothelium and alveolar epithelium.
  • 11.
    • Chronic Left-SidedHeart Failure • This condition is suggested by enlarged left-sided cardiac chambers, with evidence of pulmonary venous hypertension and with bilateral or a right-sided pleural effusion. (From 10% to 15% of patients with chronic left-sided heart failure have only a left-sided pleural effusion, which, being unusual, should prompt consideration of other causes of pleural disease.) Kerley B lines are common.

Editor's Notes

  • #10 Pulmonary hemmorhage : 1. goodpasture syndrome: penyakit auto imun yg menyebabkan inflamasi pada glomerulus/ glomerulonefritis dan alveolus. Anti-glomerular basement membrane antibody (+), usia 20-30 th atau >60 tahun, male. Xray: prominent pada regio base dan perihilar (seperti edema pulmonary)  dalam 2-3 hr, darah diabsorbsi ke interstisium  reticular interstisial  dlm 10 hari, menghilang  progresif pulmonary fibrosis 2. idiopatik pulmonary hemmorage (IPH): anak <10 th, jika pada dewasa: 2x lbh sering male Keduanya menyebabkan anemia def zat besi, episode berulang perdarahan pada paru