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Here are free downloadable DIMS LECTURE NOTES (DOCTORS ACADEMY), we made it accessible for you with removing hurdle of downloading problems. If any problem in downloading then please inform us. if you have data to provide share with us at our email address.
Dr.raiammar@gmail.com
For more Lecture notes and medical Books Follow us at facebook,
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The document discusses the benefits of meditation for reducing stress and anxiety. Regular meditation practice can help calm the mind and body by lowering heart rate and blood pressure. Making meditation a part of a daily routine, even if just 10-15 minutes per day, can have mental and physical health benefits over time by helping people feel more relaxed and better able to handle life's stresses.
This document describes Mosso's ergography experiment to study human fatigue. The experiment uses Mosso's ergograph apparatus to measure the work done by lifting weights with the middle finger over time. Various factors are tested like increasing weight, venous occlusion, and arterial occlusion. Calculations are provided to determine work done in kg-meters and time to fatigue in minutes under different conditions. The results show fatigue occurs sooner with venous occlusion due to metabolite buildup and earliest with arterial occlusion due to lack of nutrients and oxygen to the muscle. The experiment demonstrates the physiological significance of factors affecting fatigue and work done.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
High altitude physiology :Applied aspect of respiratory systemCharushila Rukadikar
Specific learning objectives
High altitude physiology
Critical altitude
Composition of air
Effect of altitude on it.
Hypoxia at high altitude
Clinical types
Clinical syndromes
Physiological compensatory response to high altitude hypoxia
Other effects of high altitude
This note paper is short notes of general physiology for medical students who which to understand the concept of the physiology, physiology is the mother of medicine.
These slides provide a simplified overview of Female Reproductive Physiology before Pregnancy by Sidra Arshad, delving into the mechanisms and physiology of the intricate cyclical changes characteristic of the female sexual cycle in the context of female reproductive hormones.
Learning objectives:
1. Briefly describe the functional anatomy of female reproductive tract
2. Explain the mechanisms responsible for initiating puberty in a female
3. Describe the role of estrogen in puberty
4. Describe the stages of oogenesis
5. Describe the development of a dominant follicle and corelate it with the phases of ovarian cycle
6. Explain the events of ovulation
7. Explain the significance of corpus luteum
8. Describe the phases of monthly endometrial/ menstrual cycle
9. Describe the functions of estrogen and progesterone
10. Summarise the regulation of the female monthly rhythm
11. Describe the process of fertilization with reference to the female reproductive tract
12. Explain how the rhythm method of contraception works
13. Describe the mechanism of action of contraceptive pills
14. Discuss a few abnormal conditions that cause infertility in females
15. Explain the physiology of menopause
Study Resources:
1. Chapter 82, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 22, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 44, Berne and Levy Physiology, 7th edition
4. Chapter 20 , Human Physiology, From Cells to Systems, Lauralee Sherwood, 9th edition
5. Chapter 10, Endocrine and Reproductive Physiology by Bruce A. White, 4th edition
6. Physiology, Ovulation – Stat Pearls; https://www.ncbi.nlm.nih.gov/books/NBK441996/
7. Physiology, Estrogen – Stat Pearls; https://www.ncbi.nlm.nih.gov/books/NBK538260/
8. Physiology, Progesterone – Stat Pearls; https://www.ncbi.nlm.nih.gov/books/NBK558960/
During the second week of embryo development:
- The blastocyst is partially or completely embedded in the endometrial lining, with the trophoblast differentiating into layers. The embryoblast also divides into the hypoblast and epiblast.
- A small cavity, the future amniotic cavity, appears in the epiblast. The syncytiotrophoblast penetrates deeper into the endometrial stroma and establishes the first circulatory system between the embryo and mother.
- By the end of the second week, the extraembryonic mesoderm and chorionic cavity have formed, and primary villi with syncytial covering have begun to develop in the chorionic cavity.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The document provides information on the ascending tracts of the spinal cord, which carry sensory information from the periphery to the brain. It discusses the three neuron pathway and lists eight major ascending tracts - the posterior white column tracts (fasciculus gracilis and cuneatus), lateral spinothalamic tract, anterior spinothalamic tract, spinocerebellar tracts, spinotectal tract, spino-olivary tract, and spinoreticular tract. Each tract is described in terms of its origin, course, termination, and function in sensory processing and perception. Lesions to different tracts can result in loss of specific sensory modalities.
cerebrum, sulci and gyri of cerebrum, lobes of cerebrum, frontal lobe , parietal lobe, temporal lobe and occipital lobe, sulci and gyri presnet in each lobes, and the functional areas , of cerebrum, brodmann areas of cerebrum, borders and surfaces of cerebrum, insula,
Stethography is a process that records respiratory movements in humans using a stethograph instrument. The stethograph is a corrugated rubber tube connected to a tambour, which is connected to a pen that writes on a moving drum. When the stethograph is applied to a person's chest, it can record their chest movements during respiration. The stethogram produced provides information about respiratory physiology by recording things like normal breathing, the effects of swallowing, hyperventilation, exercise, breath holding, and other respiratory actions.
This document summarizes the anatomy of the intercostal spaces. It describes that the intercostal spaces are located between adjacent ribs, and contain intercostal muscles and neurovascular bundles. The three types of intercostal muscles - external, internal, and innermost - are discussed, along with their actions and nerve/blood supply. The importance of the intercostal spaces in breathing, ECG placement, auscultation, and surgical access is also noted.
The document discusses the benefits of exercise for mental health. It states that regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness.
Description:
Embark on an enlightening journey with Dr. Faiza, Assistant Professor of Physiology at CIMS Multan, as she unravels the intricacies of male reproductive and hormonal functions. This comprehensive lecture explores the physiological anatomy of the male sexual organs, offering a deep dive into the blood-testis barrier and its significance in immunity.
Key Learning Objectives:
Understand the functional anatomy of male reproductive organs.
Explore the process of spermatogenesis, from initiation at puberty to sperm maturation and storage.
Examine the role of seminal vesicles and the prostate gland in male reproductive physiology.
Gain insights into abnormalities of spermatogenesis and male fertility, along with their pathophysiological basis.
Delve into the secretion and functions of testosterone, including the feedback loop regulating its production.
From the blood-testis barrier to the intricacies of spermatogenesis, Dr. Faiza guides participants through the essential hormonal and physiological aspects shaping male reproductive health. Discover the crucial role of hormones such as testosterone, luteinizing hormone, and follicle-stimulating hormone in the orchestration of spermatogenesis.
The lecture sheds light on the functions of seminal vesicles and the prostate gland, emphasizing their roles in nutrition, sperm motility, and semen alkalinity. Explore topics ranging from cryopreservation of spermatozoa to the captivating process of capacitation, and understand why only one sperm successfully fertilizes the ovum.
Dr. Faiza also addresses abnormalities in spermatogenesis, discussing conditions such as cryptorchidism, low sperm count, and issues with sperm morphology and motility. The lecture concludes with insights into male reproductive hormones, the intricacies of testosterone production, and its multifaceted functions from fetal development to adulthood.
Join us for this illuminating session on male reproductive health, ideal for students, healthcare professionals, and anyone intrigued by the wonders of human biology.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help boost feelings of calmness, happiness and focus.
The document discusses the benefits of meditation for reducing stress and anxiety. Regular meditation practice can help calm the mind and body by lowering heart rate and blood pressure. Making meditation a part of a daily routine, even if just 10-15 minutes per day, can have mental and physical health benefits over time by helping people feel more relaxed and better able to handle life's stresses.
This document describes Mosso's ergography experiment to study human fatigue. The experiment uses Mosso's ergograph apparatus to measure the work done by lifting weights with the middle finger over time. Various factors are tested like increasing weight, venous occlusion, and arterial occlusion. Calculations are provided to determine work done in kg-meters and time to fatigue in minutes under different conditions. The results show fatigue occurs sooner with venous occlusion due to metabolite buildup and earliest with arterial occlusion due to lack of nutrients and oxygen to the muscle. The experiment demonstrates the physiological significance of factors affecting fatigue and work done.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
High altitude physiology :Applied aspect of respiratory systemCharushila Rukadikar
Specific learning objectives
High altitude physiology
Critical altitude
Composition of air
Effect of altitude on it.
Hypoxia at high altitude
Clinical types
Clinical syndromes
Physiological compensatory response to high altitude hypoxia
Other effects of high altitude
This note paper is short notes of general physiology for medical students who which to understand the concept of the physiology, physiology is the mother of medicine.
These slides provide a simplified overview of Female Reproductive Physiology before Pregnancy by Sidra Arshad, delving into the mechanisms and physiology of the intricate cyclical changes characteristic of the female sexual cycle in the context of female reproductive hormones.
Learning objectives:
1. Briefly describe the functional anatomy of female reproductive tract
2. Explain the mechanisms responsible for initiating puberty in a female
3. Describe the role of estrogen in puberty
4. Describe the stages of oogenesis
5. Describe the development of a dominant follicle and corelate it with the phases of ovarian cycle
6. Explain the events of ovulation
7. Explain the significance of corpus luteum
8. Describe the phases of monthly endometrial/ menstrual cycle
9. Describe the functions of estrogen and progesterone
10. Summarise the regulation of the female monthly rhythm
11. Describe the process of fertilization with reference to the female reproductive tract
12. Explain how the rhythm method of contraception works
13. Describe the mechanism of action of contraceptive pills
14. Discuss a few abnormal conditions that cause infertility in females
15. Explain the physiology of menopause
Study Resources:
1. Chapter 82, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 22, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 44, Berne and Levy Physiology, 7th edition
4. Chapter 20 , Human Physiology, From Cells to Systems, Lauralee Sherwood, 9th edition
5. Chapter 10, Endocrine and Reproductive Physiology by Bruce A. White, 4th edition
6. Physiology, Ovulation – Stat Pearls; https://www.ncbi.nlm.nih.gov/books/NBK441996/
7. Physiology, Estrogen – Stat Pearls; https://www.ncbi.nlm.nih.gov/books/NBK538260/
8. Physiology, Progesterone – Stat Pearls; https://www.ncbi.nlm.nih.gov/books/NBK558960/
During the second week of embryo development:
- The blastocyst is partially or completely embedded in the endometrial lining, with the trophoblast differentiating into layers. The embryoblast also divides into the hypoblast and epiblast.
- A small cavity, the future amniotic cavity, appears in the epiblast. The syncytiotrophoblast penetrates deeper into the endometrial stroma and establishes the first circulatory system between the embryo and mother.
- By the end of the second week, the extraembryonic mesoderm and chorionic cavity have formed, and primary villi with syncytial covering have begun to develop in the chorionic cavity.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The document provides information on the ascending tracts of the spinal cord, which carry sensory information from the periphery to the brain. It discusses the three neuron pathway and lists eight major ascending tracts - the posterior white column tracts (fasciculus gracilis and cuneatus), lateral spinothalamic tract, anterior spinothalamic tract, spinocerebellar tracts, spinotectal tract, spino-olivary tract, and spinoreticular tract. Each tract is described in terms of its origin, course, termination, and function in sensory processing and perception. Lesions to different tracts can result in loss of specific sensory modalities.
cerebrum, sulci and gyri of cerebrum, lobes of cerebrum, frontal lobe , parietal lobe, temporal lobe and occipital lobe, sulci and gyri presnet in each lobes, and the functional areas , of cerebrum, brodmann areas of cerebrum, borders and surfaces of cerebrum, insula,
Stethography is a process that records respiratory movements in humans using a stethograph instrument. The stethograph is a corrugated rubber tube connected to a tambour, which is connected to a pen that writes on a moving drum. When the stethograph is applied to a person's chest, it can record their chest movements during respiration. The stethogram produced provides information about respiratory physiology by recording things like normal breathing, the effects of swallowing, hyperventilation, exercise, breath holding, and other respiratory actions.
This document summarizes the anatomy of the intercostal spaces. It describes that the intercostal spaces are located between adjacent ribs, and contain intercostal muscles and neurovascular bundles. The three types of intercostal muscles - external, internal, and innermost - are discussed, along with their actions and nerve/blood supply. The importance of the intercostal spaces in breathing, ECG placement, auscultation, and surgical access is also noted.
The document discusses the benefits of exercise for mental health. It states that regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help alleviate symptoms of mental illness.
Description:
Embark on an enlightening journey with Dr. Faiza, Assistant Professor of Physiology at CIMS Multan, as she unravels the intricacies of male reproductive and hormonal functions. This comprehensive lecture explores the physiological anatomy of the male sexual organs, offering a deep dive into the blood-testis barrier and its significance in immunity.
Key Learning Objectives:
Understand the functional anatomy of male reproductive organs.
Explore the process of spermatogenesis, from initiation at puberty to sperm maturation and storage.
Examine the role of seminal vesicles and the prostate gland in male reproductive physiology.
Gain insights into abnormalities of spermatogenesis and male fertility, along with their pathophysiological basis.
Delve into the secretion and functions of testosterone, including the feedback loop regulating its production.
From the blood-testis barrier to the intricacies of spermatogenesis, Dr. Faiza guides participants through the essential hormonal and physiological aspects shaping male reproductive health. Discover the crucial role of hormones such as testosterone, luteinizing hormone, and follicle-stimulating hormone in the orchestration of spermatogenesis.
The lecture sheds light on the functions of seminal vesicles and the prostate gland, emphasizing their roles in nutrition, sperm motility, and semen alkalinity. Explore topics ranging from cryopreservation of spermatozoa to the captivating process of capacitation, and understand why only one sperm successfully fertilizes the ovum.
Dr. Faiza also addresses abnormalities in spermatogenesis, discussing conditions such as cryptorchidism, low sperm count, and issues with sperm morphology and motility. The lecture concludes with insights into male reproductive hormones, the intricacies of testosterone production, and its multifaceted functions from fetal development to adulthood.
Join us for this illuminating session on male reproductive health, ideal for students, healthcare professionals, and anyone intrigued by the wonders of human biology.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help boost feelings of calmness, happiness and focus.
The document discusses the results of a study on the impact of COVID-19 lockdowns on air pollution. Researchers found that lockdowns led to significant short-term reductions in nitrogen dioxide and fine particulate matter pollution globally as transportation and industrial activities declined substantially. However, the document notes that the improvements in air quality were temporary and pollution levels rose back to pre-pandemic levels as restrictions eased and activity increased again.
Lecture 1/2022 General physiology I -Cell - nucleus and cytoplasm-Charushila Rukadikar
Brief information about all systems
1. Nucleus -
A. Nuclear membrane,
B. Nucleoplasm,
C. Nucleolus
2. Cytoplasm -
A. Organelles ,
B. Cytoplasmic inclusions , C. Cytoskeleton
Lecture 6/2022 Special senses -Vision 6 - Physiology of vision -Visual cort...Charushila Rukadikar
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help boost feelings of calmness, happiness and focus.
Lecture 4/2022 Special senses -Vision 4 -Physiology of vision - Processing o...Charushila Rukadikar
Specific learning objective
Physiology of vision
Processing & transmission of visual impulse in the retina
Horizontal cell
Bipolar cell
Amacrine cell
Ganglion cell
Lecture 1/2022 Special senses , Vision 1- Basics of vision, Optics of the eye...Charushila Rukadikar
Specific Learning Objectives
1. Functional anatomy of eye
2. Image forming mechanism
3. Principles of optics
4. Optics of the eye
5. Accommodation
6. Common defects of image forming mechanism
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms for those who already suffer from conditions like anxiety and depression.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The binding of cosmological structures by massless topological defectsSérgio Sacani
Assuming spherical symmetry and weak field, it is shown that if one solves the Poisson equation or the Einstein field
equations sourced by a topological defect, i.e. a singularity of a very specific form, the result is a localized gravitational
field capable of driving flat rotation (i.e. Keplerian circular orbits at a constant speed for all radii) of test masses on a thin
spherical shell without any underlying mass. Moreover, a large-scale structure which exploits this solution by assembling
concentrically a number of such topological defects can establish a flat stellar or galactic rotation curve, and can also deflect
light in the same manner as an equipotential (isothermal) sphere. Thus, the need for dark matter or modified gravity theory is
mitigated, at least in part.
EWOCS-I: The catalog of X-ray sources in Westerlund 1 from the Extended Weste...Sérgio Sacani
Context. With a mass exceeding several 104 M⊙ and a rich and dense population of massive stars, supermassive young star clusters
represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions
among stars.
Aims. In this paper we present the Extended Westerlund 1 and 2 Open Clusters Survey (EWOCS) project, which aims to investigate
the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars.
The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.
Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically,
the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec.
Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within
and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation
were carried out using the ACIS-Extract software.
Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a
photon flux threshold of approximately 2 × 10−8 photons cm−2
s
−1
. The X-ray sources exhibit a highly concentrated spatial distribution,
with 1075 sources located within the central 1 arcmin. We have successfully detected X-ray emissions from 126 out of the 166 known
massive stars of the cluster, and we have collected over 71 000 photons from the magnetar CXO J164710.20-455217.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Current Ms word generated power point presentation covers major details about the micronuclei test. It's significance and assays to conduct it. It is used to detect the micronuclei formation inside the cells of nearly every multicellular organism. It's formation takes place during chromosomal sepration at metaphase.
The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptxMAGOTI ERNEST
Although Artemia has been known to man for centuries, its use as a food for the culture of larval organisms apparently began only in the 1930s, when several investigators found that it made an excellent food for newly hatched fish larvae (Litvinenko et al., 2023). As aquaculture developed in the 1960s and ‘70s, the use of Artemia also became more widespread, due both to its convenience and to its nutritional value for larval organisms (Arenas-Pardo et al., 2024). The fact that Artemia dormant cysts can be stored for long periods in cans, and then used as an off-the-shelf food requiring only 24 h of incubation makes them the most convenient, least labor-intensive, live food available for aquaculture (Sorgeloos & Roubach, 2021). The nutritional value of Artemia, especially for marine organisms, is not constant, but varies both geographically and temporally. During the last decade, however, both the causes of Artemia nutritional variability and methods to improve poorquality Artemia have been identified (Loufi et al., 2024).
Brine shrimp (Artemia spp.) are used in marine aquaculture worldwide. Annually, more than 2,000 metric tons of dry cysts are used for cultivation of fish, crustacean, and shellfish larva. Brine shrimp are important to aquaculture because newly hatched brine shrimp nauplii (larvae) provide a food source for many fish fry (Mozanzadeh et al., 2021). Culture and harvesting of brine shrimp eggs represents another aspect of the aquaculture industry. Nauplii and metanauplii of Artemia, commonly known as brine shrimp, play a crucial role in aquaculture due to their nutritional value and suitability as live feed for many aquatic species, particularly in larval stages (Sorgeloos & Roubach, 2021).
ESPP presentation to EU Waste Water Network, 4th June 2024 “EU policies driving nutrient removal and recycling
and the revised UWWTD (Urban Waste Water Treatment Directive)”
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024