This document summarizes the capabilities of the RAMDO software for reliability-based design optimization (RBDO). It discusses both sensitivity-based and sampling-based RBDO approaches in RAMDO. It also provides examples of multidisciplinary applications of RAMDO in areas like fatigue analysis, casting process design, vehicle crashworthiness, and more. Several published case studies demonstrate how RAMDO has been used to optimize designs while accounting for input variability and reliability constraints.