Khure Health is a clinical decision support tool that uses AI to help physicians identify and care for patients with rare and complex conditions. It analyzes data from electronic medical records to instantly screen patients and identify those at high risk. The platform groups patients into risk categories and provides clinical criteria showing why each patient is at risk. It also provides clinical pathways, referral forms, and other tools to help optimize care. Currently it can screen for 78 rare diseases with a goal of adding more, including some chronic conditions, to reach 100 diseases by International Rare Disease Day in 2022.

2. Khure Health
Clinical Intelligence & Decision Support for Rare & Complex Conditions
Mission:
To help physicians save lives and end the suffering of rare and
complex disease patients and their families through the use of
advanced AI.
How:
• Harness the power of AI through a powerful clinical
decision-support tool
• Help physicians put the vast amounts of data sitting idle in
their EMR to good use for proactive, personalized patient
care

3. Khure Health’s Clinical Intelligence Platform
Instantly Screen EMR to Identify High-Risk Patients
• Rare Disease focused: AI-enabled algorithms to instantly
identify at risk patients and clinical support to help optimize
care pathways
• Instant In-Visit Screen: Screen a challenging patient
against all available pathologies instantly
• Advanced Education: Education material and accredited
programs available
• Participate in Clinical Research: algorithms based on
protocols, instantly identify High Fit patients for trials.
• Free to Canadian physicians as a result of our work with
Patient Advocacy Groups, Pharma, CROs and Academia

4. Khure Health’s Clinical Intelligence Platform
Instant Results Showing Patients at Risk
• Click-of-a-button complete practice reflective
• Instant summary results
• Patients grouped into risk categories:
o High-risk
o At Risk
o Flagged

5. Khure Health’s Clinical Intelligence Platform
Showing Patient Specific Clinical Criteria Indicating Risk
• Full EMR analysis of medications,
labs, reports, symptoms, longitudinal
history, physician notes
• Product & Service: Khure team
provides clinical care pathway support
for rare conditions and platform
navigation
• Streamlined Workflows: pre-
populated referral forms and lab
requisitions

6. Pathologies currently on the Khure Health platform
78 and counting (with integration of chronic conditions in development)
1. Aagenaes Syndrome
2. Acquired Hemophilia A
3. Adult Dermatomyositis
4. Adult ITP (Idiopathic Thrombocytopenic Purpura)
5. Adult Onset Still's Disease
6. Adult Polymyositis
7. Alpha Thalassemia
8. Ankylosing Spondylitis
9. Aquired Pure Red Cell Aplasia
10. Atypical Hemolytic Uremic Syndrome
11. Autosomal Dominant Polycystic Kidney Disease
12. Beta Thalassemia
13. Chronic Idiopathic Urticaria
14. Cushing's Syndrome
15. Diabetic Macular Edema
16. Essential Thrombocythemia
17. Fabry's Disease
18. Gaucher's Disease
19. Giant Cell Arteritis
20. hATTR Amyloidosis
21. Henoch Schonlein Purpura
22. Hepatitis C Virus (HCV)
23. Hepatopulmonary Syndrome
24. Hereditary Angiodema (HAE)
25. Hereditary Elliptocytosis
26. Hereditary Spherocytosis
27. HHRH (Hereditary Hypophosphatemic Rickets with Hypercalciuria)
28. Hunter Syndrome
29. Hurlers Disease
30. Hypophophatasia
31. Hypophosphatemia X-Linked
32. Juvenile Dermatomyositis
33. Juvenile ITP (Idiopathic Thrombocytopenic Purpura)
34. Juvenile Polymyositis
35. Kawasaki Disease
36. Loeyz-Dietz Syndrome
37. Multiple Myeloma
38. Mutli-focal Motor Neuropathy
39. Myelofibrosis
40. Neuroblastoma
41. Neuromyelitis Optica Spectrum Disorder
42. Paroxysmal Nocturnal Hemoglobinuria
43. Pompe Disease
44. PPP (Palmoplantar Pustular Psoriasis)
45. Primary Biliary Cholangitis
46. Pulmonary Arterial Hypertension
47. Severe Allergic Asthma
48. Severe Eosinophilic Asthma
49. Sideroblastic Anemia
50. Thrombotic Thrombocytopenic Purpura
51. Typical Hemolytic Uremic Syndrome
52. Von Willebrand’s
53. AA Amyloidosis
54. Atrial Fibrillation
55. Bernard-Soulier Syndrome
56. Brugada Syndrome
57. Cold Agglutinin Disease
58. Ebstein anomaly
59. Eisenmenger syndrome
60. Fanconi Anemia
61. Glanzmann Thrombasthenia
62. Immune Thrombocytopenia Purpura (ITP)
63. Marfans Syndrome
64. Myelodysplastic Syndrome
65. Non-ischemic pediatric cardiomyopathy
66. Patent ductus arteriosus
67. Polycythemia Vera
68. Psoariatic Arthritis
69. Severe Plaque Psoriasis
70. Shprintzen-Goldberg syndrome
71. Sickle Cell Anemia
72. ALS
73. nmCRPC
74. Transthretin Amyloid Cardiomyopathy
75. Recurrent Fever Syndromes
76. Castlemen's Disorder
77. Neiman Pick
78. Primary Sclerosing Cholangitis

7. Pathologies on the Khure Health Platform
100 by February 28, 2022 (International Rare Disease Day)
79. Rheumatoid Arthritis
80. Secondary hyperparathyroidism
81. Spinal Muscular Atrophy
82. Long-Chain Fatty Acid Oxidation Disorders
83. Anaplastic lymphoma kinase (ALK)-positive metastatic Non-small cell lung cancer
84. Best Vitelliform Macular Dystrophy
85. Budd-Chiari Syndrome
86. Cerebral Adrenoleukodystrophy
87. Cone Dystrophy
88. Cystic Fibrosis
89. Emphysema - severe hereditary deficiency of alpha1-PI alpha1-antitrypsin deficiency)
90. Endometrosis
91. Guillan-Barre Syndrome
92. Hemi-Plegic Migraines
93. Hepatopulmonary Syndrome
94. Juvenile idiopathic arthritis
95. Metastatic Colorectal Cancer
96. Morquio syndrome
97. Multiple Sclerosis (Remitting-Relapsing)
98. Myasthenia gravis
99. Narcolepsy
100. B-cell precursor acute lymphoblastic leukemia (relapsed or refractory)
By Specialty Total:100
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Immunology
Obstetrics & Gynaecology
Urology
Dermatology
Gastroenterology
Nephrology
Ophthamology
Pulmonology
Endocrinology
Hepatology
Metabolic
Oncology
Neurology
Cardiology
Rheumatology
Hematology