Congenital valvular heart disease in pregnancy :
analyzing risk factors of delivering low birth
weight neonates
Karina Niken Pratiwi, Pangeran Akbar Syah, Ardhia
Kusuma Putri, Oktavia Lilyasari, Radityo Prakoso
Background :
Valvular
Heart
DIsease
Christine M, Warrick MD, Jan E, et al. Prevalence and descriptive analysis of congenital heart disease in
parturients : obstetric, nenonatal,and aesthetic outcomes
Fetus and neonate at risk of : SGA,
Prematurity, IUFD, neonatal death, low
birth weight
Congenital cardiac lesions
are 3 times higher than
acquired
Affecting heamodynamic
changes
Rao S, ginns JN. Adult congenitalheat disease and pregnancy. Seminars of perinatology. 2014
Methods
Data were collected through a year period from April
2013 – April 2014 in Cipto Mangunkusumo General
Hospital
Incomplete records were
excluded
142 Pregnancy
Complicated with
Congenital Heart
Disease
42 Congenital
Heart Disease
Diagnosed by clinical
examination, electrocardiograph,
laboratory, chest x-ray,
echocardiograph examination
• maternal age
• parity
• Ejection Fraction
• Week of gestation
• MAP
• anemia during antenatal care
(ANC), labor
Risk Factors
Bivariate and multivariate analysis using SPSS
Results
Variable p-value Adjusted OR* 95%CI
Preterm birth 0.009*
0.052 0.006 – 0.483
Multiparous 0.169 0.312 0.059 – 1.642
DiscussionThis Study Other studies
Prevalence
Congenital Heart
Disease in Pregnancy
142/ 4561 CHD in
pregnancy
117/18.226 CHD in
pregnancy (Warrick
CM et al )
Prevalence
Congenital Valvular
Heart Disease in
Pregnancy
30% (42/142) Valvular
Heart Disease in
pregnancy with CHD
• Preterm birth (aOR 0.052) • Multiparous
P<0.05 P>0.05
Premature birth rate appeared higher in patients with more complex
CHD. Premature birth tend to deliver nenonates with low birth weight
Warrick CM et al. Prevalence and descriptive analysis of congenital heart disease in parturients: obstetric, neonatal, and anesthetic outcomes. Journal of clinical
Aesthesia. 2015
Conclusions
Preterm birth in women with congenital valvular heart
disease were the risk factor of Delivering low birth weight
neonates.
Karina Niken Pratiwi, MD - UCCVS2016

Karina Niken Pratiwi, MD - UCCVS2016

  • 1.
    Congenital valvular heartdisease in pregnancy : analyzing risk factors of delivering low birth weight neonates Karina Niken Pratiwi, Pangeran Akbar Syah, Ardhia Kusuma Putri, Oktavia Lilyasari, Radityo Prakoso
  • 2.
    Background : Valvular Heart DIsease Christine M,Warrick MD, Jan E, et al. Prevalence and descriptive analysis of congenital heart disease in parturients : obstetric, nenonatal,and aesthetic outcomes
  • 3.
    Fetus and neonateat risk of : SGA, Prematurity, IUFD, neonatal death, low birth weight Congenital cardiac lesions are 3 times higher than acquired Affecting heamodynamic changes Rao S, ginns JN. Adult congenitalheat disease and pregnancy. Seminars of perinatology. 2014
  • 5.
    Methods Data were collectedthrough a year period from April 2013 – April 2014 in Cipto Mangunkusumo General Hospital Incomplete records were excluded 142 Pregnancy Complicated with Congenital Heart Disease 42 Congenital Heart Disease Diagnosed by clinical examination, electrocardiograph, laboratory, chest x-ray, echocardiograph examination • maternal age • parity • Ejection Fraction • Week of gestation • MAP • anemia during antenatal care (ANC), labor Risk Factors Bivariate and multivariate analysis using SPSS
  • 6.
  • 8.
    Variable p-value AdjustedOR* 95%CI Preterm birth 0.009* 0.052 0.006 – 0.483 Multiparous 0.169 0.312 0.059 – 1.642
  • 9.
    DiscussionThis Study Otherstudies Prevalence Congenital Heart Disease in Pregnancy 142/ 4561 CHD in pregnancy 117/18.226 CHD in pregnancy (Warrick CM et al ) Prevalence Congenital Valvular Heart Disease in Pregnancy 30% (42/142) Valvular Heart Disease in pregnancy with CHD • Preterm birth (aOR 0.052) • Multiparous P<0.05 P>0.05 Premature birth rate appeared higher in patients with more complex CHD. Premature birth tend to deliver nenonates with low birth weight Warrick CM et al. Prevalence and descriptive analysis of congenital heart disease in parturients: obstetric, neonatal, and anesthetic outcomes. Journal of clinical Aesthesia. 2015
  • 10.
    Conclusions Preterm birth inwomen with congenital valvular heart disease were the risk factor of Delivering low birth weight neonates.

Editor's Notes

  • #9 Cofounding : yang mempngearhui dependen dan independen.
  • #11 Kami berharap penelitian lanjutan dapat dilakukan dengan design prospective dan faktor resiko yang lebih komprehensive. TERIMAKASIH ata sperhatiannya.