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Malaria
a story of ELIMINATION
A partnership of:
T oday, we know
some things about
malaria...
We know the main culprits
parasites & mosquitoes...
Malaria parasites
(genre: Plasmodium)
Female mosquitoes
(genre: Anopheles)
We know how it’s transferred
to people...
Transmission of parasites via
mosquito bite
and more…
and more people
and more....
and more…
We know how to control it:
prevention
Insecticide treated
bed nets
Indoor residual
spraying
Drugs
(prophylactic use)
vs mosquitoes vs vector-human
contact
vs the parasite
Environmental
interventions
Larvicides
We know how to control it:
Rapid Diagnostic
Tests
Microscopy
&
diagnosis treatment
ACTs
(Artemisinin-based
Combination Therapies)
Other drugs
We know how far we’ve come...
Malaria endemic areas
1900
1946
Malaria endemic areas
1975
Malaria endemic areas
2002
Malaria endemic areas
2010
Malaria endemic areas
...and we know 99 countries
are still malaria endemic,
although
United Arab Emirates
2007
Morocco & Turkmenistan
2010
Armenia
2011 2012
Kazakhstan
5 have been acknowledged by WHO as
in the past six years:
“MALARIA FREE”
We also know
just how far we NEED to go:
In 2010
Malaria
Killed an estimated
660,000
People
with an estimated
219 million
Currently
1/2
of the world
population
lives in
countries
where
transmission
continues
cases
BURDEN
of
MALARIA
…and we must
face the daily
In Africa, the economic growth is
hindered every year due
to the costs associated to malaria
In some African countries the cost to prevent and
treat the disease may be up to 1/3 of the
families total annual income
In countries like Tanzania, they spend nearly
40% of their entire health budget
to fight malaria
Resistance to
Drugs
Resistance to
Insecticides
Environmental
Changes
On top of ALL of this
we face significant
CHALLENGES:
On top of ALL of this
we face significant
CHALLENGES:
Risk of reintroduction
& resurgence
Sustaining
funds
Sustaining political
commitment & public
awareness
and most importantly:
oday’s malaria
story is about
T control & elimination,
and working together
towards global eradication.
But available tools are
not enough in some parts
of the world…
- Joint statement of the Malaria Eradication Research Agenda
(malERA) Initiative Leadership Council, January 2011.
“
The dream of ending this
scourge of humanity is within
reach, but demands our BEST
COLLECTIVE EFFORTS”
Malaria elimination means:
1. NO local transmission
2. ZERO infections in a
defined-geographical area
Transmission of parasites
In other words, we need to
interrupt transmission
and eliminate all reservoirs
To achieve elimination, we must treat
infections and prevent mosquitoes from
passing the parasites
means
= less than one new infection
per existing infection
R 1
<
0
that one infection…
does not cause another…
…and another
BLOCKING
transmission
Malaria elimination
is strengthening R&D to develop new
ways of interrupting transmission
New insecticides New drugs that kill all
stages of the parasite
life cycle
Vaccines that interrupt
malaria transmission
...with these
NEW TOOLS & STRATEGIES
we aim to:
Drive down transmission and block it
Eliminate the very last infections
Keep infection rate at zero
malaria infection
0
3 years with NO local
malaria transmission =
ELIMINATION
Elimination worldwide =
ERADICATION
Eradication =
LIBERATION
from malaria for
all of humanity
For more
information:
www.isglobal.org

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ISGlobal-Malaria-A-Story-of-Elimination.ppt

  • 1. Malaria a story of ELIMINATION A partnership of:
  • 2. T oday, we know some things about malaria...
  • 3. We know the main culprits parasites & mosquitoes... Malaria parasites (genre: Plasmodium) Female mosquitoes (genre: Anopheles)
  • 4. We know how it’s transferred to people... Transmission of parasites via mosquito bite and more… and more people and more.... and more…
  • 5. We know how to control it: prevention Insecticide treated bed nets Indoor residual spraying Drugs (prophylactic use) vs mosquitoes vs vector-human contact vs the parasite Environmental interventions Larvicides
  • 6. We know how to control it: Rapid Diagnostic Tests Microscopy & diagnosis treatment ACTs (Artemisinin-based Combination Therapies) Other drugs
  • 7. We know how far we’ve come... Malaria endemic areas 1900
  • 12. ...and we know 99 countries are still malaria endemic, although United Arab Emirates 2007 Morocco & Turkmenistan 2010 Armenia 2011 2012 Kazakhstan 5 have been acknowledged by WHO as in the past six years: “MALARIA FREE”
  • 13. We also know just how far we NEED to go: In 2010 Malaria Killed an estimated 660,000 People with an estimated 219 million Currently 1/2 of the world population lives in countries where transmission continues cases
  • 14. BURDEN of MALARIA …and we must face the daily In Africa, the economic growth is hindered every year due to the costs associated to malaria In some African countries the cost to prevent and treat the disease may be up to 1/3 of the families total annual income In countries like Tanzania, they spend nearly 40% of their entire health budget to fight malaria
  • 15. Resistance to Drugs Resistance to Insecticides Environmental Changes On top of ALL of this we face significant CHALLENGES:
  • 16. On top of ALL of this we face significant CHALLENGES: Risk of reintroduction & resurgence Sustaining funds Sustaining political commitment & public awareness and most importantly:
  • 17. oday’s malaria story is about T control & elimination, and working together towards global eradication. But available tools are not enough in some parts of the world…
  • 18. - Joint statement of the Malaria Eradication Research Agenda (malERA) Initiative Leadership Council, January 2011. “ The dream of ending this scourge of humanity is within reach, but demands our BEST COLLECTIVE EFFORTS”
  • 19. Malaria elimination means: 1. NO local transmission 2. ZERO infections in a defined-geographical area Transmission of parasites
  • 20. In other words, we need to interrupt transmission and eliminate all reservoirs To achieve elimination, we must treat infections and prevent mosquitoes from passing the parasites
  • 21. means = less than one new infection per existing infection R 1 < 0 that one infection… does not cause another… …and another BLOCKING transmission
  • 22. Malaria elimination is strengthening R&D to develop new ways of interrupting transmission New insecticides New drugs that kill all stages of the parasite life cycle Vaccines that interrupt malaria transmission
  • 23. ...with these NEW TOOLS & STRATEGIES we aim to: Drive down transmission and block it Eliminate the very last infections Keep infection rate at zero malaria infection 0
  • 24. 3 years with NO local malaria transmission = ELIMINATION