ISB is a biotechnology company founded in 2006 and located in Gerenzano, Italy that provides mass spectrometry services and develops customized analytical applications and kits. Its mission is to simplify the mass spectrometry field for customers by developing methods and applications that can be directly used in its labs or transferred to customers through customized kit production. ISB offers a range of proteomics, metabolomics, quantitative and qualitative analysis, and other services using various mass spectrometry techniques.

1. ISB - Ion Source & Biotechnologies
Simone Cristoni, Ph.D.
Founder & CEO
Phone: +39-0296474437
Email: simone.cristoni@isbiolab.com
ISB-Headquarters & Laboratories: Insubrias Biopark, Via Roberto Lepetit 34 Gerenzano (VA) – Italy.
Tel. 02/96474438; Fax 02/700410252 info@isbiolab.com

2. Company Overview
Founded on September 5th, 2006
ISB Core Business
We semplify mass spectrometry world

3. Strategic Location
Insubrias BioPark
is one of the eight technological parks and bio-incubators of the Italian
biotechnology sector. It is located in Gerenzano, Varese. The BioPark
covers an area of 52,000sm; 15,000sm of which include office space
and laboratories, equipped with the most advanced technologies in the
bio-medical sector.
The BioPark is located in a beautiful green area in a geographical and economical
strategic position aiming at creating an effective network of partners in the territory. It was
created by the cooperation of Italian and Swiss entrepreneurship found in the historical
area called Insubriac Region, shared by Lombardia, Piemonte and Cantone Ticino.

4. Mission
Classical strategy: from product to customer
SERVICES CUSTOMIZED kits
ISB offers an extensive array APPLICATIONS
After the development,
of services, ranging from ISB develops standardized ISB produces and sells
development of customized analytical applications that analytical kits (reagent,
analytical methods, to the can be directly used in our controls, proprietary
analysis of molecules for laboratory or transferred to technology etc) to apply
R&D purposes (e.g: the customer through the developed method on
biomarker discovery, customized kit production. the customer’s
proteomics, metabolomics) instrument.
ISB strategy: from customer to product

5. Proteomic Services
ISB provides a comprehensive range of proteomics services using
both gel-based and gel-free proteome analysis platforms.
Protein separation by monodimensional gel electrophoresis
Protein identification from SDS-PAGE, 2-D electrophoresis by LC-MS/MS
(Database searching and De novo sequencing) *
Characterization of post-translational modifications (e.g. phosphorylation)
Global small proteins/peptides profiling with quantitative comparisons
between samples
Targeted small proteins/peptides profiling with quantitative comparisons
between samples
Comparative proteomics: “Label free approach” for identification of
differentially expressed proteins using SACI (Surface Activated Chemical
Ionization) technology
* 350 € + IVA (21%) for each spot/band

6. Other services
1. Analyses of metabolomic profiles for disease early diagnosis & biomarker discovery
Development of innovative technologies for the detection of metabolites in biological
fluids (plasma, urines, cell extracts)
Creation of novel possible diagnostic strategies based on the database search
software NIST ‘The National Institute of Standards and Technologies’ for an
effective disease early diagnosis & biomarker discovery (e.g. cancer)
2. Quantitative and qualitative analyses of compounds, even at trace levels, from different
matrices (e.g. street drugs, peticides, pharmaceuticals, hormones)
3. Characterization of complex mixtures (e.g. plant extracts) by USIS (Universal Soft Ionization
Source)and SACI (Surface Activated Chemical Ionization) technologies.
4. Determination of exact mass of compounds and characterization of their formula bruta
5. Search for molecules of nutraceutical interest in plant extracts (e.g. pulp extracts)
6. Analyses of volatile organic compounds (VOCs) from biological fluids or foods

7. ISB Contacts
Contact us:
Dr. Simone Cristoni
Tel: +39-02-96474438 Cel: +39-340-9639745
e-mail: simone.cristoni@isbiolab.com
e-mail2: simone.cristoni@gmail.com
Web page: http://www.isbiolab.com