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For growth promotion through mycoplasma and
necrotic enteritis prevention
INNOKITINNOKIT(20% Kitasamycin micro-granulated Premix )
Efficiency
Effectiveness
Economy
Synergy at Work...Linco Vis G
Lincomycin 11% and Allicin 25% premix
(Colistin Sulfate 10% granular premix)
Many growth promoters and mycoplasma prevention programs have been used over the decades in chickens.
INNOKIT (Kitasamycin) is a new generation macrolide antibiotic for improving performance efficiency through
controlling infections related to mycoplasma and Clostridium perfringens.The antibacterial spectrum of Kitasamycin
iscomparabletotylosin,erythrocin,selectomycin,medecamycinandoleandomycin.
Kitasamycin works on 50S ribosome subunit of the sensitive bacteria to refrain from the synthesizing bacterial
protein by prohibition of peptide transfer action or m RNA shift INNOKIT has strong activity against G positive and
someGnegativebacteria,leptospira,rickettsiosis,mycoplasma,andsome viruses.
l Usingspecialaqueousentericmaterialandcuttingedgespraying-drytechnologytomakethecoating.
l MuchlessdestructionofKitasamycininacidicstomachandthebioavailabilityisincreasedby30-40%.
l NoirritationtostomachandG.I.tractofpoultryandswine.
l NobittertastesoInnokitdoesnotaffectthefeedintake.
l The particle technology increase the surface area of Innokit so it is more effective than unprocessed
Kitasamycin(Competitor)
l Broad spectrum antibacterial, particularly it has an obvious action on mycoplasma causing respiratory
diseaseofthelivestock.
l Low toxicity.Kitasamycin is a special antibiotic for livestock with high safety levels. Taken orally it has quick
absorbability. It can spread to various tissues and organs, in particular, it keeps higher plasma drug
concentrationcontinuouslyinbloodandlungtissues.
High stabilityinthefeed–nolossofactivityatpelletingtemperatures.
l Low residue. Administer large dose of kitasamycin (330-500m/kg) in the fodder to feed livestock
continuouslyfor14daysthenstop.Onthethirddayofwithdrawal,residueintissuesislessthan0.03mg/kg.
l Good growth promotion effect. Adding it with small dosage continuously can not only prevent the
disease,butpromoteanimals’growth
l High Safety. Kitasamycin has the highest compatability with all polyether antibiotics (Ionophores) compared
toanyotherin-feedantibiotic
Innokit can be used to cure the infection caused by gram positive bacteria, mycoplasma, clostridia, leptospira, and
promote growth in chickens.It mainly prevents from the diseases of intestinal and respiratory tract infection- chicken
necroticenteritiscausedbyclostridiumperfringensandCRDcausedmycoplasmaspp.
Usage and Dose in Feed
For Broilers:100 grams per ton of feed in all phases for growth promotion effects – prevention and control of CRD
andNecroticEnteritis.
For Breeders as Mycoplasma Prevention Program:
1000 grams per ton of feed for 2 days-every-week fromWeek 1 toWeek 24.Later 250 to 500 grams per ton of feed
uptocullingonadailyfeedingbasis.
For Layers:
500 grams per ton of feed for 2 days-every-week from Week 1 to Week 18. Later 250 grams per ton of feed upto
cullingonadailyfeedingbasis.
For treatment of Mycoplasmosis in chickens:1to2kgper tonoffeedfor5-7days.
l Un-processed Kitasamycin is quickly absorbed and metabolized within poultry GI Tract (less than 3 hours).
Therefore,itislesseffectiveinpoultryasgrowthpromoter.
l Because Kitasamycin is quickly transported into blood stream, there is less amount of Kitasamycin in G.I. tract
andcausespoorresultsofgrowthpromotion.
l Un-processed Kitasamycin has irritation to poultry stomach, causing reduction of feed intake and a slower
growth.
l Un-processed Kitasamycin has bitter taste, negatively affecting the palatability, so the feed intake can be
negativelyaffected.
l Theacidicsolutioninfore-gutcandestroytheactivityofKitasamycin.
25 Kg. in HDPE bag with inner polyliner.
Pharmacology
Product Description
Features
Indications
Problems using un-processed Kitasamycin powder (Competitor) as growth
promoters in Poultry
Presentation
Stable antibiotic growth promoter to
control gram negative infections
ColiVis
Lincomycin
Garlic –TheWonder Drug
Key Features
LincoVis G – Creating Synergies – 3 E's for more profits!
Dosage/Administration
Packing:
Storage :
Shelf Life :
A lincosamide antibiotic, one of the most commonly used antimicrobial feed additive in poultry to
increase weight gains and feed efficiency. Lincomycin is specifically active against gram positive
pathogens and anaerobic bacteria of clostridia spp. Lincomycin has beneficial effects to treat Necrotic
enteritis and mycoplasma.Therefore,lincomycin supplementation in feed can help improve performance
andhasbeenusedasaregularrotationoptionamongsttheexistingantibioticgrowthpromoters.
(Allicin- garlic oil extracts):
“History and all its wise men have extolled the virtues of garlic. Hippocrates, Galen, Pliny the Elder, and
Dioscorides, all have, at some point of time or another, mentioned the use of garlic for many disease
conditions that include parasitic infections, respiratory problems and poor digestion. Garlic first finds
mentioninA.D.510Chinesemedicaltreatise.Inmoderntimes,LouisPasteurhasconfirmedthegoodness
ofgarlicanditsanti-bacterialnaturein1858”.
“In its natural form, garlic is a pungent pod.The pungency is a result of allyl thiosulfinates, which are a
groupoforgano-sulfurcompoundswithauniquechemistry.TheactiveingredientingarliciscalledAllicin,
a volatile oil containing sulfur that is responsible for its pungent odor.These and some other compounds
in garlic help to protect the body from a large number of harmful conditions, sometimes even fatal
diseases”.
· Allicinhasbroadspectrum,non-specificantibacterial,antifungal,antiviralandanti-oxidant effects,
· Hasafeedattractanteffect: increasesappetite,increasesfeedintake,
· Pronouncedimpactongutmicroflora,
· Improvesurvivalrate,
· Increases egg production in laying birds, improves fertility in breeders, Improves FCR and weight
gainsinbroilers.
· Supportsleanmeatproductionandimprovesmeatqualitybyreducingfat
· Has antifungal effect: Tests have shown that use of of garlicin on Aspergillus flavus, Aspergillus
Niger,Aspergillus fumigatus has a very strong inhibition and cidal effect, therefore can effectively
preventmoldformation,improvekeepingqualityoffeedasanalternativefeedpreservative.
· Allicinisnon-toxicandhasnosideeffects.
· Nocrossresistancewithotherin-feedantibiotics.
For Increase in Rate ofWeight Gain and Improved Feed Efficiency:
LINCOVIS G should be mixed into the complete feed supplied to broiler chickens so that the final feed
contains40gramsofLincoVisGpertonoffeed.
For the Control of Necrotic Enteritis:
LINCOVIS G should be mixed into the complete feed supplied to broiler chickens so that the final feed
contains 40 grams of LincoVis G per ton of feed.
No drug withdrawal period before slaughter is required for poultry fed LINCOVIS G Feed Medication at
therecommendedlevel.
25kg/bag
Wellpreservedincoolanddryplace.
24months
Appearance
Content
Characteristics
Strong antibacterial action
Good Compatability
Good Stability
Good Security
Good Flowability
Actions
Dosage per ton of finished feed:(Recommended for reference only)
Precaution
Packaging:
Storage:
Shelf life:
Lightyellowcolor,granular,freeflowing,odorless
100 gm:10gm(300millioncolistinunits)
Broad antibiotic spectrum - Has strong antibiotic activity on gram negative bacteria such as
E.coli, Salmonella and Pseudomonas aeruginosa, etc. It is effective on prevention and
treatmentofentericdiseasescausedbybacteria.
Its effect mechanism is by blocking cell membrane selective permeation function. Thus, it is
very effective on killing enteric pathogenic bacteria, but no drug resistance profile is
established.
Bettereffectivenessincombinationwithgram-positiveantibacterialdrug.
Itisnoteffectedbyfeedenzymeandsecretivesubstances.
Nosideeffects,noresiduesinanimalbody
Granular product, no dust, no static electricity and no degradation and loss of activity in the
processofstorageandfeedmilling.
· Preventandcureloosedroppings,causedbygramnegativebacteriainpoultry,cattle
andswine.
· Promotegrowthandbetterperformance
· Improvefeedconversionratioandincreaselivability
Poultry:50to200grams
Cattle:50to400grams
Swine:50to200grams
Withdrawal period:Stop using 7 days before slaughter.Forbid using during the laying period in
layers.
25kgbags
Keep inventilatedanddryplaceandavoiddirectlight
24monthsinoriginalpacking
MegaCOXMegaCOX
12.5% Nicarbazin + 1% Maduramicin Ammonium unique granular Premix
RobiDON(Robenidine Hcl 10%, granular formulation)
The Bio-Regulator Acidifier and Performance Enhancer
KONZERVEKONZERVE PlusPlus
(Sodium Butyrate 90%, Coated, Granular Formulation)
MegaCOX provides an unique combination of ionophore maduramycin and chemical
nicarbazine for synergistic action against coccidiosis.MegaCOX offers superior performance in
weight gains over higher level of nicarbazine or recommended levels of ionophores. It is an
ideal starter for broader protection in a convenient year-round alternative to competitors both
inpriceandperformance.
1. Broadspectrumandhighefficacy.
2. Canbeusedinsummertime(temperaturesof35degreeCelsiusandabove)
3. Canbeusedincombinationwithcommongrowthpromoters.
4. Anticoccidiosis effect can be enhanced when used in combination with Innokit
(Kitasamycin20%)orLincoVisG.
As an aid in the prevention of coccidiosis caused by Eimeria necatrix,E.tenella,E.acervulina,E.
brunetti,E.maximaandE.mitisinbroilerchickens.
1. Donotfeedtoturkeysorbreedinghensinproduction.
2. Donotusethismixtureforthetreatmentofoutbreaksofcoccidiosis.
500g/Tfeed,mixedwiththefeedevenly.Feedcontinuouslyasthesoleration.
4daysbeforeslaughter.
25kg/bag
Wellconservedincoolanddryplace.
24months.
Characteristics
Indication
Caution
Dosages andAdministration
Withdrawal Period
Package:
Storage:
Shelf Life:
Proven
composition
of ionophore
and chemical
anticoccidials for
fighting high
cocci
challenges
Marketed by:
Office: Suite No. A-602,
Vasundhra CGHS,
Plot 16, Sector 6,
Dwarka, New Delhi, INDIA
ZIP: 110075
Email: office@innovistaconsulting.com
Innovista Consulting
YOUR PARTNER FOR PROFIT
www.innovistaconsulting.com
Marketing Solutions & Services Provider
In poultry productivity, to maintain a healthy gut is of immense importance. Short chain fatty acids
have an outstanding effect in maintaining gut health through their different area of action. Short
chain fatty acids successfully maintain the gut health in the anterior part of gastrointestinal tract.The
posterior part along with the caecum remains a challenge due to the inability of various short chain
fattyacidstoreachthere,inanundissociatedform.
KONZERVE Plus is a bio-regulator acidifier, which is comprised of a short chain fatty acid i.e. a
pureformofsodiumsaltofn-Butyricacid.
KONZERVE Plus CH -[CH ] – COONa3 2 2
KONZERVE Plus is Sodium Butyrate (90%) Coated with cellulose. This protects Sodium
Butyrate from being hygroscopic and covers up the pungent odor. KONZERVE Plus help to release
Sodium Butyrate at the gut. So the full potency of the salt can be achieved at the required site of
action.
The Butyric acid in KONZERVE Plus enters the microbial cell in undissociated form.Within the cell it
releases protons in an alkaline environment which results the decrease of intracellular pH. This
decrease of pH influences microbial metabolism by inhibiting the action of important microbial
enzymes. Microbial cells try to excrete proton by using its energy and ultimately end up to death.
KONZERVE Plus also supplies energy to the epithetical cells of villi to recover its damage caused by
theenteritis.
Dissociation
- +
CH -[CH ] – COOH - CH -[CH ] – COO + H3 2 2 3 2 2
In an undissociated state KONZERVE Plus is strongly lipophilic and easily cross membranes. The
dissociation rate is low due to its high pka value.The dissociation rate is also influenced by the pH of
theintestinalliquid.KONZERVE Plusremains
undissociatedeveninhighpHinthelargeintestineowingtoitshighpKavalueascomparedtoformic
acidandlacticacid.
KONZERVE Plus increases the Hemoglobin synthesis and stimulates the non specific and local
immunity.
KONZERVE Plus correlates lipopolysaccharides from pathogenic bacteria in such a way that it
controls the nitric oxide production. KONZERVE Plus stimulates proliferation of beneficial bacteria's
likeBifidobacteriaandlactobacillus.
KONZERVE Plus increases the length of the villi at the ileum by 30%. This implies a major
improvementofabsorptiveanddigestivecapacityandhenceincreasesthebodyweightofthebroiler.
· Broilers(0-21days) : 250gm./TonofFeed.
· Broilers(22d-market) : 150gm./TonofFeed.
· CommercialLayers : 250gm./TonofFeed.
· Breeders : 250gm./TonofFeed.
· WeanedPiglet : 600gm./TonofFeed.
· Growing&FinishingPigs : 300gm./TonofFeed.
KONZERVE Plus
Mode of Action
BENEFIT 1:Immunomodutatory effect
BENEFIT 2:Biological effect
KONZERVE Plus Dosage
Technical Papers
· Butyric acid-based feed additives protect
broiler chickens from Salmonella
enteritidis infection - Poultry Science
AssociationInc-R.Balf
· Supplementation of coated Butyric acid in
the feed reduces colonization and
shedding of Salmonella in poultry-Dept.
ofPathology,GHENTUniversity,Belgium.
· Microencapsulated SCFA in feed modify
colonization and invasion early after
infection with Salmonella Enteritidis in
young chicken - Dept. of Pathology,
GHENTUniversity,Belgium.
RobiDON comprises of a potent chemical anticoccidial Robenidine Hcl highly effective on
both caecal and intestinal coccidiosis. RobiDON has very low toxicity. It provides for an
idealsolutionforstarterprogramduringhighcoccidiosischallenges.
1. BroadSpectrumactivityinpreventionofpoultrycoccidiosis
2. Effectiveincontrolofcaecalandintestinalcoccidiosis
3. EffectiveonmultiplestagesoflifecycleEimeriaspp.ofPoultry
4. Lowtoxicity
Prevention of caecal and intestinal coccidiosis
330 grams per ton of feed incorporated in feed evenly
Bestresultswhenrotatedandshuttledwithmaduramycinandsalinomycin
20kg per carton
Well conserved in cool and dry place.
24 months.
Characteristics
Indications
Dosage and Administration
Caution
Packing
Storage
Shelf Life

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  • 1. For growth promotion through mycoplasma and necrotic enteritis prevention INNOKITINNOKIT(20% Kitasamycin micro-granulated Premix ) Efficiency Effectiveness Economy Synergy at Work...Linco Vis G Lincomycin 11% and Allicin 25% premix (Colistin Sulfate 10% granular premix) Many growth promoters and mycoplasma prevention programs have been used over the decades in chickens. INNOKIT (Kitasamycin) is a new generation macrolide antibiotic for improving performance efficiency through controlling infections related to mycoplasma and Clostridium perfringens.The antibacterial spectrum of Kitasamycin iscomparabletotylosin,erythrocin,selectomycin,medecamycinandoleandomycin. Kitasamycin works on 50S ribosome subunit of the sensitive bacteria to refrain from the synthesizing bacterial protein by prohibition of peptide transfer action or m RNA shift INNOKIT has strong activity against G positive and someGnegativebacteria,leptospira,rickettsiosis,mycoplasma,andsome viruses. l Usingspecialaqueousentericmaterialandcuttingedgespraying-drytechnologytomakethecoating. l MuchlessdestructionofKitasamycininacidicstomachandthebioavailabilityisincreasedby30-40%. l NoirritationtostomachandG.I.tractofpoultryandswine. l NobittertastesoInnokitdoesnotaffectthefeedintake. l The particle technology increase the surface area of Innokit so it is more effective than unprocessed Kitasamycin(Competitor) l Broad spectrum antibacterial, particularly it has an obvious action on mycoplasma causing respiratory diseaseofthelivestock. l Low toxicity.Kitasamycin is a special antibiotic for livestock with high safety levels. Taken orally it has quick absorbability. It can spread to various tissues and organs, in particular, it keeps higher plasma drug concentrationcontinuouslyinbloodandlungtissues. High stabilityinthefeed–nolossofactivityatpelletingtemperatures. l Low residue. Administer large dose of kitasamycin (330-500m/kg) in the fodder to feed livestock continuouslyfor14daysthenstop.Onthethirddayofwithdrawal,residueintissuesislessthan0.03mg/kg. l Good growth promotion effect. Adding it with small dosage continuously can not only prevent the disease,butpromoteanimals’growth l High Safety. Kitasamycin has the highest compatability with all polyether antibiotics (Ionophores) compared toanyotherin-feedantibiotic Innokit can be used to cure the infection caused by gram positive bacteria, mycoplasma, clostridia, leptospira, and promote growth in chickens.It mainly prevents from the diseases of intestinal and respiratory tract infection- chicken necroticenteritiscausedbyclostridiumperfringensandCRDcausedmycoplasmaspp. Usage and Dose in Feed For Broilers:100 grams per ton of feed in all phases for growth promotion effects – prevention and control of CRD andNecroticEnteritis. For Breeders as Mycoplasma Prevention Program: 1000 grams per ton of feed for 2 days-every-week fromWeek 1 toWeek 24.Later 250 to 500 grams per ton of feed uptocullingonadailyfeedingbasis. For Layers: 500 grams per ton of feed for 2 days-every-week from Week 1 to Week 18. Later 250 grams per ton of feed upto cullingonadailyfeedingbasis. For treatment of Mycoplasmosis in chickens:1to2kgper tonoffeedfor5-7days. l Un-processed Kitasamycin is quickly absorbed and metabolized within poultry GI Tract (less than 3 hours). Therefore,itislesseffectiveinpoultryasgrowthpromoter. l Because Kitasamycin is quickly transported into blood stream, there is less amount of Kitasamycin in G.I. tract andcausespoorresultsofgrowthpromotion. l Un-processed Kitasamycin has irritation to poultry stomach, causing reduction of feed intake and a slower growth. l Un-processed Kitasamycin has bitter taste, negatively affecting the palatability, so the feed intake can be negativelyaffected. l Theacidicsolutioninfore-gutcandestroytheactivityofKitasamycin. 25 Kg. in HDPE bag with inner polyliner. Pharmacology Product Description Features Indications Problems using un-processed Kitasamycin powder (Competitor) as growth promoters in Poultry Presentation Stable antibiotic growth promoter to control gram negative infections ColiVis Lincomycin Garlic –TheWonder Drug Key Features LincoVis G – Creating Synergies – 3 E's for more profits! Dosage/Administration Packing: Storage : Shelf Life : A lincosamide antibiotic, one of the most commonly used antimicrobial feed additive in poultry to increase weight gains and feed efficiency. Lincomycin is specifically active against gram positive pathogens and anaerobic bacteria of clostridia spp. Lincomycin has beneficial effects to treat Necrotic enteritis and mycoplasma.Therefore,lincomycin supplementation in feed can help improve performance andhasbeenusedasaregularrotationoptionamongsttheexistingantibioticgrowthpromoters. (Allicin- garlic oil extracts): “History and all its wise men have extolled the virtues of garlic. Hippocrates, Galen, Pliny the Elder, and Dioscorides, all have, at some point of time or another, mentioned the use of garlic for many disease conditions that include parasitic infections, respiratory problems and poor digestion. Garlic first finds mentioninA.D.510Chinesemedicaltreatise.Inmoderntimes,LouisPasteurhasconfirmedthegoodness ofgarlicanditsanti-bacterialnaturein1858”. “In its natural form, garlic is a pungent pod.The pungency is a result of allyl thiosulfinates, which are a groupoforgano-sulfurcompoundswithauniquechemistry.TheactiveingredientingarliciscalledAllicin, a volatile oil containing sulfur that is responsible for its pungent odor.These and some other compounds in garlic help to protect the body from a large number of harmful conditions, sometimes even fatal diseases”. · Allicinhasbroadspectrum,non-specificantibacterial,antifungal,antiviralandanti-oxidant effects, · Hasafeedattractanteffect: increasesappetite,increasesfeedintake, · Pronouncedimpactongutmicroflora, · Improvesurvivalrate, · Increases egg production in laying birds, improves fertility in breeders, Improves FCR and weight gainsinbroilers. · Supportsleanmeatproductionandimprovesmeatqualitybyreducingfat · Has antifungal effect: Tests have shown that use of of garlicin on Aspergillus flavus, Aspergillus Niger,Aspergillus fumigatus has a very strong inhibition and cidal effect, therefore can effectively preventmoldformation,improvekeepingqualityoffeedasanalternativefeedpreservative. · Allicinisnon-toxicandhasnosideeffects. · Nocrossresistancewithotherin-feedantibiotics. For Increase in Rate ofWeight Gain and Improved Feed Efficiency: LINCOVIS G should be mixed into the complete feed supplied to broiler chickens so that the final feed contains40gramsofLincoVisGpertonoffeed. For the Control of Necrotic Enteritis: LINCOVIS G should be mixed into the complete feed supplied to broiler chickens so that the final feed contains 40 grams of LincoVis G per ton of feed. No drug withdrawal period before slaughter is required for poultry fed LINCOVIS G Feed Medication at therecommendedlevel. 25kg/bag Wellpreservedincoolanddryplace. 24months Appearance Content Characteristics Strong antibacterial action Good Compatability Good Stability Good Security Good Flowability Actions Dosage per ton of finished feed:(Recommended for reference only) Precaution Packaging: Storage: Shelf life: Lightyellowcolor,granular,freeflowing,odorless 100 gm:10gm(300millioncolistinunits) Broad antibiotic spectrum - Has strong antibiotic activity on gram negative bacteria such as E.coli, Salmonella and Pseudomonas aeruginosa, etc. It is effective on prevention and treatmentofentericdiseasescausedbybacteria. Its effect mechanism is by blocking cell membrane selective permeation function. Thus, it is very effective on killing enteric pathogenic bacteria, but no drug resistance profile is established. Bettereffectivenessincombinationwithgram-positiveantibacterialdrug. Itisnoteffectedbyfeedenzymeandsecretivesubstances. Nosideeffects,noresiduesinanimalbody Granular product, no dust, no static electricity and no degradation and loss of activity in the processofstorageandfeedmilling. · Preventandcureloosedroppings,causedbygramnegativebacteriainpoultry,cattle andswine. · Promotegrowthandbetterperformance · Improvefeedconversionratioandincreaselivability Poultry:50to200grams Cattle:50to400grams Swine:50to200grams Withdrawal period:Stop using 7 days before slaughter.Forbid using during the laying period in layers. 25kgbags Keep inventilatedanddryplaceandavoiddirectlight 24monthsinoriginalpacking
  • 2. MegaCOXMegaCOX 12.5% Nicarbazin + 1% Maduramicin Ammonium unique granular Premix RobiDON(Robenidine Hcl 10%, granular formulation) The Bio-Regulator Acidifier and Performance Enhancer KONZERVEKONZERVE PlusPlus (Sodium Butyrate 90%, Coated, Granular Formulation) MegaCOX provides an unique combination of ionophore maduramycin and chemical nicarbazine for synergistic action against coccidiosis.MegaCOX offers superior performance in weight gains over higher level of nicarbazine or recommended levels of ionophores. It is an ideal starter for broader protection in a convenient year-round alternative to competitors both inpriceandperformance. 1. Broadspectrumandhighefficacy. 2. Canbeusedinsummertime(temperaturesof35degreeCelsiusandabove) 3. Canbeusedincombinationwithcommongrowthpromoters. 4. Anticoccidiosis effect can be enhanced when used in combination with Innokit (Kitasamycin20%)orLincoVisG. As an aid in the prevention of coccidiosis caused by Eimeria necatrix,E.tenella,E.acervulina,E. brunetti,E.maximaandE.mitisinbroilerchickens. 1. Donotfeedtoturkeysorbreedinghensinproduction. 2. Donotusethismixtureforthetreatmentofoutbreaksofcoccidiosis. 500g/Tfeed,mixedwiththefeedevenly.Feedcontinuouslyasthesoleration. 4daysbeforeslaughter. 25kg/bag Wellconservedincoolanddryplace. 24months. Characteristics Indication Caution Dosages andAdministration Withdrawal Period Package: Storage: Shelf Life: Proven composition of ionophore and chemical anticoccidials for fighting high cocci challenges Marketed by: Office: Suite No. A-602, Vasundhra CGHS, Plot 16, Sector 6, Dwarka, New Delhi, INDIA ZIP: 110075 Email: office@innovistaconsulting.com Innovista Consulting YOUR PARTNER FOR PROFIT www.innovistaconsulting.com Marketing Solutions & Services Provider In poultry productivity, to maintain a healthy gut is of immense importance. Short chain fatty acids have an outstanding effect in maintaining gut health through their different area of action. Short chain fatty acids successfully maintain the gut health in the anterior part of gastrointestinal tract.The posterior part along with the caecum remains a challenge due to the inability of various short chain fattyacidstoreachthere,inanundissociatedform. KONZERVE Plus is a bio-regulator acidifier, which is comprised of a short chain fatty acid i.e. a pureformofsodiumsaltofn-Butyricacid. KONZERVE Plus CH -[CH ] – COONa3 2 2 KONZERVE Plus is Sodium Butyrate (90%) Coated with cellulose. This protects Sodium Butyrate from being hygroscopic and covers up the pungent odor. KONZERVE Plus help to release Sodium Butyrate at the gut. So the full potency of the salt can be achieved at the required site of action. The Butyric acid in KONZERVE Plus enters the microbial cell in undissociated form.Within the cell it releases protons in an alkaline environment which results the decrease of intracellular pH. This decrease of pH influences microbial metabolism by inhibiting the action of important microbial enzymes. Microbial cells try to excrete proton by using its energy and ultimately end up to death. KONZERVE Plus also supplies energy to the epithetical cells of villi to recover its damage caused by theenteritis. Dissociation - + CH -[CH ] – COOH - CH -[CH ] – COO + H3 2 2 3 2 2 In an undissociated state KONZERVE Plus is strongly lipophilic and easily cross membranes. The dissociation rate is low due to its high pka value.The dissociation rate is also influenced by the pH of theintestinalliquid.KONZERVE Plusremains undissociatedeveninhighpHinthelargeintestineowingtoitshighpKavalueascomparedtoformic acidandlacticacid. KONZERVE Plus increases the Hemoglobin synthesis and stimulates the non specific and local immunity. KONZERVE Plus correlates lipopolysaccharides from pathogenic bacteria in such a way that it controls the nitric oxide production. KONZERVE Plus stimulates proliferation of beneficial bacteria's likeBifidobacteriaandlactobacillus. KONZERVE Plus increases the length of the villi at the ileum by 30%. This implies a major improvementofabsorptiveanddigestivecapacityandhenceincreasesthebodyweightofthebroiler. · Broilers(0-21days) : 250gm./TonofFeed. · Broilers(22d-market) : 150gm./TonofFeed. · CommercialLayers : 250gm./TonofFeed. · Breeders : 250gm./TonofFeed. · WeanedPiglet : 600gm./TonofFeed. · Growing&FinishingPigs : 300gm./TonofFeed. KONZERVE Plus Mode of Action BENEFIT 1:Immunomodutatory effect BENEFIT 2:Biological effect KONZERVE Plus Dosage Technical Papers · Butyric acid-based feed additives protect broiler chickens from Salmonella enteritidis infection - Poultry Science AssociationInc-R.Balf · Supplementation of coated Butyric acid in the feed reduces colonization and shedding of Salmonella in poultry-Dept. ofPathology,GHENTUniversity,Belgium. · Microencapsulated SCFA in feed modify colonization and invasion early after infection with Salmonella Enteritidis in young chicken - Dept. of Pathology, GHENTUniversity,Belgium. RobiDON comprises of a potent chemical anticoccidial Robenidine Hcl highly effective on both caecal and intestinal coccidiosis. RobiDON has very low toxicity. It provides for an idealsolutionforstarterprogramduringhighcoccidiosischallenges. 1. BroadSpectrumactivityinpreventionofpoultrycoccidiosis 2. Effectiveincontrolofcaecalandintestinalcoccidiosis 3. EffectiveonmultiplestagesoflifecycleEimeriaspp.ofPoultry 4. Lowtoxicity Prevention of caecal and intestinal coccidiosis 330 grams per ton of feed incorporated in feed evenly Bestresultswhenrotatedandshuttledwithmaduramycinandsalinomycin 20kg per carton Well conserved in cool and dry place. 24 months. Characteristics Indications Dosage and Administration Caution Packing Storage Shelf Life