Indonesia
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The document discusses a country that is facing a drug crisis, with over 16 million illegal drug users that the government has largely ignored. While the country has a population of around 17,500 islands and is economically emerging, its future will be affected if it doesn't address its large number of drug users and implement effective treatment and policy solutions. Tourism is also an industry that intersects with the widespread drug problems.
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Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
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Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
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Indonesia
- 1. A Country In Crisis Christina Haynes
- 2. Geography Population Economics Politics Summary Religion Tourism Treatment Solution
- 3. A Country With A Drug Problem
- 5. LA to NYC
- 6. Cosmopolitan
- 7. Remote
- 9. 16,120,000 Illegal Drug Users
- 10. Government Looks The Other Way
- 11. Economic Future Will Be Affected
- 12. Emerging Economy
- 13. 86% Muslim Though Not An Islamic State
- 15. Tourism and Drugs Go Hand In Hand
- 16. Drug Seizures