In a single strand of DNA, the individual nucleotides are covalenty linked together by bonds, indirecty linking the of adjacent pentose sugars In a single strand of DNA, the individual nucleotides are covalently linked together by. bonds, indrectly liking the di ajpcet petsse guss phosphodiester, bases phosphodiester, 2' carbon and 3' carbon hydrogen; 3 ' carbon and 2 ' carbon phosphodiester, 5 carbon and 3 carbon hydrogen; bases.