Histochemistry in pathology and it'sbranches.pptxDrMUSTAFAAlAmeri
Thi is a simple overview about histochemistry and its branches, how the histological diseases can be diagnosed and what methods are used to examine the tissue.
PROTEINS: Proteins are the large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds.
Protein > 50 amino acids
PEPTIDES: These are short polymers formed from the linking, in a defined order of amino acids.
Peptide < 50 amino acids
Cell biology is the study of cell structure and function, and it revolves around the concept that the cell is the fundamental unit of life. Focusing on the cell permits a detailed understanding of the tissues and organisms that cells compose.
Protein and Peptide drug delivery system are the Novel drug Delivery System. Proteins and peptides are the most abundant components of biological cells. They exist functioning such as enzymes, hormones, structural element and immunoglobulin. Proteins and peptides are therefore almost exclusively administered by the parenteral route. Although parenteral administration serves the purpose, it has several shortcomings. It encounters, many barriers affecting its stability, such as poor cellular membrane permeability at the GIT site, enzymatic degradation (various proteases), and first-pass hepatic metabolism.
Histochemistry in pathology and it'sbranches.pptxDrMUSTAFAAlAmeri
Thi is a simple overview about histochemistry and its branches, how the histological diseases can be diagnosed and what methods are used to examine the tissue.
PROTEINS: Proteins are the large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds.
Protein > 50 amino acids
PEPTIDES: These are short polymers formed from the linking, in a defined order of amino acids.
Peptide < 50 amino acids
Cell biology is the study of cell structure and function, and it revolves around the concept that the cell is the fundamental unit of life. Focusing on the cell permits a detailed understanding of the tissues and organisms that cells compose.
Protein and Peptide drug delivery system are the Novel drug Delivery System. Proteins and peptides are the most abundant components of biological cells. They exist functioning such as enzymes, hormones, structural element and immunoglobulin. Proteins and peptides are therefore almost exclusively administered by the parenteral route. Although parenteral administration serves the purpose, it has several shortcomings. It encounters, many barriers affecting its stability, such as poor cellular membrane permeability at the GIT site, enzymatic degradation (various proteases), and first-pass hepatic metabolism.
OMICS is the comprehensive analysis of the biological system. The technologies which made a revolution such as Genomics, Transcriptomics, Proteomics, Metabolomics and Phenomics, in screening traits and develop novel improved organisms are mentioned here. The presentation gives a brief idea about various OMICS technology used in crop improvement, their steps, techniques used, applications, scope, advantages and disadvantages.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
OMICS is the comprehensive analysis of the biological system. The technologies which made a revolution such as Genomics, Transcriptomics, Proteomics, Metabolomics and Phenomics, in screening traits and develop novel improved organisms are mentioned here. The presentation gives a brief idea about various OMICS technology used in crop improvement, their steps, techniques used, applications, scope, advantages and disadvantages.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
How to Create Map Views in the Odoo 17 ERPCeline George
The map views are useful for providing a geographical representation of data. They allow users to visualize and analyze the data in a more intuitive manner.
This is a presentation by Dada Robert in a Your Skill Boost masterclass organised by the Excellence Foundation for South Sudan (EFSS) on Saturday, the 25th and Sunday, the 26th of May 2024.
He discussed the concept of quality improvement, emphasizing its applicability to various aspects of life, including personal, project, and program improvements. He defined quality as doing the right thing at the right time in the right way to achieve the best possible results and discussed the concept of the "gap" between what we know and what we do, and how this gap represents the areas we need to improve. He explained the scientific approach to quality improvement, which involves systematic performance analysis, testing and learning, and implementing change ideas. He also highlighted the importance of client focus and a team approach to quality improvement.
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
Andreas Schleicher presents at the OECD webinar ‘Digital devices in schools: detrimental distraction or secret to success?’ on 27 May 2024. The presentation was based on findings from PISA 2022 results and the webinar helped launch the PISA in Focus ‘Managing screen time: How to protect and equip students against distraction’ https://www.oecd-ilibrary.org/education/managing-screen-time_7c225af4-en and the OECD Education Policy Perspective ‘Students, digital devices and success’ can be found here - https://oe.cd/il/5yV
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Digital Tools and AI for Teaching Learning and Research
histochemistryoforaltissues-160811144259.pdf
1.
2. What is
histochemistry?
It is the study of qualitative identification &
quantitative assessment of chemical
groupings within cells and tissues.
Histochemical techniques are based on
precise chemical rationales for their ability to
identify or stain different biochemical
substances.
Visualizing Chemicals and Enzymes in
Tissue.
3. Based on chemical reactions between
cell components and stains.
The end products of the reaction are
permanent, colored precipitates that
can be viewed under the microscope.
There are stains specific to each
component of the cell, based on the
basic or acidic nature of the dye.
10. Histochemical study of teeth
and bone
Simultaneous fixation and decalcification with
formaldehyde or gluteraldehyde and EDTA
(ethylenediaminetetraacetic acid) for light and
electron microscopic histochemistry.
Recently techniques have been developed for
sectioning freeze-dried, undecalcified tissues.
(eg: for studying DC).
Bone- deproteinization with conc. Hydrazine.
11. Specific histochemical methods
Carbohydrates- PAS
Proteoglycans- Toluidine blue, Azure A, Alcian
blue.
Proteins- Dinitrofluorobenzene, Ninhydrin or
Ferric ferricyanide
Lipids- Sudan dyes (Sudan black- phospholipids)
Enzymes (For eg-Phosphatases- Gomori
method)
12. Immunohistochemistry
Immunohistochemistry takes advantage of
antigen-antibody affinity through its ability to
identify and localize proteins of interest via
detection with labelled conjugates (fluorescent
dyes).
13.
14. Enzyme Histochemistry
The techniques of enzyme histochemistry, which relate
structure and function, can be used to locate many enzymes,
including acid phosphatase, dehydrogenases, and
peroxidases.
Enzymes indicates what is happening in the tissue
15. Histochemistry of Oral hard
tissues
Carbohydrates(PAS)
Proteins (dinitrofluorobenzene, ninhydrin or
ferric ferricyanide)
Lipids(Sudan dyes)
16. Enzyme histochemistry
Alkaline phosphatase- absorption
Adenosine triphosphatase- pre absorptive
ameloblasts
Acid phosphatase- resorption
Esterase- matrix of bone and dentin
Aminopeptidase- human osteoclasts
Cytochrome oxidase- oxidation (osteoblasts,
osteoclasts)
Succinate dehydrogenase- osteoclasts
17. Histochemistry of oral soft tissues
Polysaccharides
Proteins
Lipids
Mucins(PAS for neutral mucins & alcian blue
for acid mucins)
