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The Hippocampus
By. AAMIR ALI VEESAR
Visit us:
w w w . S t u d y Q u i c k l y . m l
 The hippocampus is the structure in the brain
most closely aligned to memory formation.
 It is important as an early storage place for
long–term memory, and it is involved in the
transition of long–term memory to even more
enduring permanent memory.
 The hippocampus also plays an important
role in spatial navigation.
Visit us:
w w w . S t u d y Q u i c k l y . m l
 In 1985, Clive Wearing, an English conductor, composer,
and musician, contracted viral encephalitis, which caused
extensive damage to the left and right hippocampus.
 Although his intellectual and perceptual abilities are intact,
he has severe memory impairments and has completely
lost the ability to form new declarative memories.
 This causes him to assume he has just awoken from a
coma, writing repetitively in his diary, “I am awake!” The
inability to remember has severely debilitated his life – he
cannot engage in conversation (he forgets the previous
sentence), he cannot go outside alone (he forgets where
he is going or coming from), and he is incapable of
comprehending the events that essentially define his
existence.
Visit us:
w w w . S t u d y Q u i c k l y . m l
• early memory storage
• formation of long–term memory
• spatial navigation
Visit us:
w w w . S t u d y Q u i c k l y . m l
 Classic symptoms of Alzheimer's disease
include memory loss and disorientation both
of which have been strongly associated with
decline in the hippocampus (Scheff and Price,
2006).
 There is also evidence linking hippocampal
atrophy to depression (e.g. Sheline and
colleagues, 2002), bipolar disorder, and
schizophrenia (Weis and colleagues, 2007).
Visit us:
w w w . S t u d y Q u i c k l y . m l
• severe memory impairment
• disorientation
Visit us:
w w w . S t u d y Q u i c k l y . m l

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Hippocampus

  • 1. The Hippocampus By. AAMIR ALI VEESAR Visit us: w w w . S t u d y Q u i c k l y . m l
  • 2.  The hippocampus is the structure in the brain most closely aligned to memory formation.  It is important as an early storage place for long–term memory, and it is involved in the transition of long–term memory to even more enduring permanent memory.  The hippocampus also plays an important role in spatial navigation. Visit us: w w w . S t u d y Q u i c k l y . m l
  • 3.  In 1985, Clive Wearing, an English conductor, composer, and musician, contracted viral encephalitis, which caused extensive damage to the left and right hippocampus.  Although his intellectual and perceptual abilities are intact, he has severe memory impairments and has completely lost the ability to form new declarative memories.  This causes him to assume he has just awoken from a coma, writing repetitively in his diary, “I am awake!” The inability to remember has severely debilitated his life – he cannot engage in conversation (he forgets the previous sentence), he cannot go outside alone (he forgets where he is going or coming from), and he is incapable of comprehending the events that essentially define his existence. Visit us: w w w . S t u d y Q u i c k l y . m l
  • 4. • early memory storage • formation of long–term memory • spatial navigation Visit us: w w w . S t u d y Q u i c k l y . m l
  • 5.  Classic symptoms of Alzheimer's disease include memory loss and disorientation both of which have been strongly associated with decline in the hippocampus (Scheff and Price, 2006).  There is also evidence linking hippocampal atrophy to depression (e.g. Sheline and colleagues, 2002), bipolar disorder, and schizophrenia (Weis and colleagues, 2007). Visit us: w w w . S t u d y Q u i c k l y . m l
  • 6. • severe memory impairment • disorientation Visit us: w w w . S t u d y Q u i c k l y . m l