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High-Gradient FFL Simulations
for Human-Sized MPI
Lucas Jenkins, MGH Wald Lab
Background and Goals
 For Magnetic Particle Imaging, an integral part of the hardware setup is the main
magnetic gradient
 The strength of the magnetic field gradient is directly correlated to the possible
resolution of the Magnetic Particle Image
 Previous MPI scanners have all had bores that would fit rats
 The goal of these simulations was to create a high gradient in a human-sized bore.
Software Used
 COMSOL Multiphysics 5.1
 AC/DC Module
 Magnetic Fields, No Currents package (mfnc)
 Magnetic Fields package (mf)
 Licensed from MIT
Location of .mph Files From Simulations
 Stored on MIT Linux box jotunn.mit.edu:2
 /
 home
 clzimmer
 mpi_sims
 Anything with prefix “Lucas”
 To see all: $ls /home/clzimmer/mpi_sims/Lucas*
Materials Simulated: Permanent Magnets
 Used in mfnc module
 Magnet specs from http://www.magnet4less.com/index.php?cPath=1_122
 N52 Grade Neodymium Magnets used – remnant flux density BrMax = 14,800 gauss
= 1.48 T
 Some arc magnets used – but for the most part, combinations of 4cm x 1cm x
1/2cm N52 magnets used to create different geometries
 Other important property for permanent magnets: μrelative
 Neodymium μrelative = 1.05
 Air μrelative = 1
 For simulations with iron yolks - μrelative of iron can vary with field strength – I chose an
intermediate value from what I had seen for Low Carbon Cold Rolled (aka laminated)
Annealed Steel of μrelative = 1200
Approaches for Permanent Magnets
 Many different geometries of permanent magnets were simulated
 1.) Arc Magnets
 2.) 2 opposite sets of Magnets ***
 3.) Magnets set up at Vertices of Equilateral Triangle
 4.) Quadrupole Magnet
 Some geometries were also simulated with an iron yolk around the magnets to
concentrate the flux lines
***Most successful method for FFL
List of all Simulations
(some with descriptive
names)
First approach– 2 opposing sets of 2
4x1x1” N52 magnets
 Relatively short magnets
 North Poles faced inward
(towards other set of magnets)
 Not successful – magnets
were not tall enough
 Not thick enough
 Takeaways – try taller
and thicker magnets
Results from first attempt – more of a field
free point than FFL
Red arrows are flux density norms (small fields)
Y-Z Plane View X-Z Plane View X-Y Plane View
First Results (continued)
Cut lines endpoints (cm): Y Field and Gradient (0, -15, 5.08)  (0, 15, 5.08) **z=5.08cm is centered in z dir
Z Field and Gradient (0, 0, -10)  (0, 0, 20)
X Field and Gradient (-10, 0, 5.08)  (10, 0, 5.08)
Second approach – 2 Opposing Tall
Arc-Shaped Magnets
 Again, North poles faced inwards
 Geometric Properties (arcs are identical but opposite):
 ID of arc: 10.16cm
 OD of arc: 17.78cm
 y coordinate of the center of each arc: ±9cm (x=0)
 Inner arc angle = 180°
 Extrusion Height: 60cm
Intermediate Geometric Step
(distances in cm)
Arc Magnet Results
 Better than small magnets
 Arc shape did not seem to help
 Height and thickness made main difference
 Gradient strengths still too weak
 Again, red arrows are flux density norms
Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
Arc Magnet Results (continued)
Cut lines endpoints (cm): Y Field and Gradient (0, -30, 30)  (0, 30, 30) **z=30cm is centered in z dir
Z Field and Gradient (0, 0, 10)  (0, 0, 50)
X Field and Gradient (-10, 0, 5.08)  (10, 0, 5.08)
Low x and y gradients at center = unfit for MPI
Third Approach: Triangular Setup
 Place groups of magnets at vertices of
equilateral triangle with side length=36cm.
 Groups of:
 single 1x1” N52 magnets
 2 side by side 1x1” N52 magnets
 And a 2x2 square of 1x1” N52 magnets
 Were used in these simulations
 Results from 2x2 square (best results) are
shown
 Extrusion Height (z-dir) = 60mm
Triangular Approach Results
 Magnetic fields from each group of magnets were directed at center of triangle –
however, this meant that the fields were not evenly opposed
 As can be seen in the Y-Z plane view, flux distributions were uneven
Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
Triangular Flux Density Plots
We struggled to plot the gradients along non-axial lines in COMSOL,
but given the similar flux density curves for the y-axis field and the
field along Cut Lines 3 and 4, we assume that the gradient curves
along Cut Lines 3 and 4 were similar to the Y Gradient, as the
geometric and magnetic properties of the magnets at each vertex of
the triangle were identical.
The Y Axis Field and Cut Lines 3 and 4 emanated from
magnet groups at the vertices of the triangle
Cut Line 3:
Cut Line 4:
Triangular Magnets Takeaways
 Gradients too small
 Fields do not cancel effectively at center
 R^2 decreasing field effects seem to dominate flux decrease as opposed to true
cancellations – theme of all simulations so far = low slope magnetic fields
 Unfit for human MPI
Two Sets of Opposing Magnets pt. II
 Two sets of opposing magnets – taller with different geometric layout
 3 magnets in the back and 4 in the front (1”x1” N52)
 70cm extrusion
Optimized Opposing Magnets Results
Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
Optimized Opposing Magnets Results (cont.)
Optimized Opposing Magnets Results
 First Example of actual Free Field “Line” in Spectrum/Arrow plots
 Gradient Strength of 0.5 T/m still relatively low – thicker magnets may help?
 Gradients of at least 1-2 T/m desired
 Optimized opposite magnets do not quite reach desired gradients - quadrupole
magnets were attempted next
Quadrupole Magnetic Setup
 Quadrupole Magnets are a rough
approximation to a k=3 Halbach cylinder,
leaving no field in the center of the bore
 Our quadrupole setup used the same 4+3
1x1” groups of magnets placed on the vertices
of an imaginary square of diagonal 36 cm
 This setup left ~18.5 cm between each corner
magnet – enough room for an average human
head to slide in sideways while leaving the FFL
approximately at the center of the head
 Extrusion height of 70 cm
Quadrupole Magnets Results
Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
 Most clear free field line for permanent magnets
 Promising Results – line is very uniform for whole length of magnet – can shorten
magnet?
Quadrupole Magnets Results
 Magnetic Flux density curve look uniform for 30 cm around center of magnet in z
direction – x and y flux density curves are nearly identical
 Gradient strengths approaching desired levels – could possibly be increased with
Iron Yolk?
Yolked Quadrupole Setup
 Quadrupole magnets are in same arrangement as previous simulation
 Iron Yolk placed around Magnets with hole through direction which allows head
entrance
Cold Rolled (laminated) annealed steel used in
simulation with μrelative = 1200
Goal with yolk is to concentrate flux lines within the yolk,
ideally increasing gradient
Note – yolked simulations for dual opposite magnets in
same folder, not as successful
Yolked Quadrupole results
Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
 Slightly more uniform gradients – gradient falls off more
slowly in z-dir compared to no yolk
Yolked Quadrupole results
 Gradients are >1 T/m – possibly high enough for human sized
MPI (althought maybe claustrophobic).
 Yolk seems to add ~0.3 T/m to gradient at center
Electromagnetic Simulations
 Not as many simulations done as for static magnetic fields
 Copper coils with cross section of 1.25mm were used as inductors
 Golay gradient coils were simulated – inverse Helmholtz coils remain a future
simulation
 Due to COMSOL’s use of Magnetic Potential to calculate Magnetic Flux, the
magnetic flux elements calculated in the AC/DC mf module needed to be mapped
to a coefficient PDE so that Lagrangian elements could be used to calculate the
gradient of the magnetic flux density
Golay Coil Setup
 8 sets of 17.5cm radius arcs – connected by straight lines as
shown. Arc angle is 120 degrees
 Current flows in the same direction on the 2 upper inner arcs,
and in the opposite direction on the 2 lower inner arcs
 Coils excited with 100V at the center of the outside arc
Golay Coil Results
 All simulations can be found in the mpi_sims folder
 Some results:
Golay Coil Results
 Higher gradients can be created with electromagnets than permanent magnets
 Electromagnets are more complex to simulate in COMSOL
 Future efforts would go towards mastering the Magnetic Fields interface in
COMSOL, and simulating inverted Helmholtz coils

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High-Gradient FFL Simulations for Human-Sized Bore MPI

  • 1. High-Gradient FFL Simulations for Human-Sized MPI Lucas Jenkins, MGH Wald Lab
  • 2. Background and Goals  For Magnetic Particle Imaging, an integral part of the hardware setup is the main magnetic gradient  The strength of the magnetic field gradient is directly correlated to the possible resolution of the Magnetic Particle Image  Previous MPI scanners have all had bores that would fit rats  The goal of these simulations was to create a high gradient in a human-sized bore.
  • 3. Software Used  COMSOL Multiphysics 5.1  AC/DC Module  Magnetic Fields, No Currents package (mfnc)  Magnetic Fields package (mf)  Licensed from MIT
  • 4. Location of .mph Files From Simulations  Stored on MIT Linux box jotunn.mit.edu:2  /  home  clzimmer  mpi_sims  Anything with prefix “Lucas”  To see all: $ls /home/clzimmer/mpi_sims/Lucas*
  • 5. Materials Simulated: Permanent Magnets  Used in mfnc module  Magnet specs from http://www.magnet4less.com/index.php?cPath=1_122  N52 Grade Neodymium Magnets used – remnant flux density BrMax = 14,800 gauss = 1.48 T  Some arc magnets used – but for the most part, combinations of 4cm x 1cm x 1/2cm N52 magnets used to create different geometries  Other important property for permanent magnets: μrelative  Neodymium μrelative = 1.05  Air μrelative = 1  For simulations with iron yolks - μrelative of iron can vary with field strength – I chose an intermediate value from what I had seen for Low Carbon Cold Rolled (aka laminated) Annealed Steel of μrelative = 1200
  • 6. Approaches for Permanent Magnets  Many different geometries of permanent magnets were simulated  1.) Arc Magnets  2.) 2 opposite sets of Magnets ***  3.) Magnets set up at Vertices of Equilateral Triangle  4.) Quadrupole Magnet  Some geometries were also simulated with an iron yolk around the magnets to concentrate the flux lines ***Most successful method for FFL
  • 7. List of all Simulations (some with descriptive names)
  • 8. First approach– 2 opposing sets of 2 4x1x1” N52 magnets  Relatively short magnets  North Poles faced inward (towards other set of magnets)  Not successful – magnets were not tall enough  Not thick enough  Takeaways – try taller and thicker magnets
  • 9. Results from first attempt – more of a field free point than FFL Red arrows are flux density norms (small fields) Y-Z Plane View X-Z Plane View X-Y Plane View
  • 10. First Results (continued) Cut lines endpoints (cm): Y Field and Gradient (0, -15, 5.08)  (0, 15, 5.08) **z=5.08cm is centered in z dir Z Field and Gradient (0, 0, -10)  (0, 0, 20) X Field and Gradient (-10, 0, 5.08)  (10, 0, 5.08)
  • 11. Second approach – 2 Opposing Tall Arc-Shaped Magnets  Again, North poles faced inwards  Geometric Properties (arcs are identical but opposite):  ID of arc: 10.16cm  OD of arc: 17.78cm  y coordinate of the center of each arc: ±9cm (x=0)  Inner arc angle = 180°  Extrusion Height: 60cm Intermediate Geometric Step (distances in cm)
  • 12. Arc Magnet Results  Better than small magnets  Arc shape did not seem to help  Height and thickness made main difference  Gradient strengths still too weak  Again, red arrows are flux density norms Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
  • 13. Arc Magnet Results (continued) Cut lines endpoints (cm): Y Field and Gradient (0, -30, 30)  (0, 30, 30) **z=30cm is centered in z dir Z Field and Gradient (0, 0, 10)  (0, 0, 50) X Field and Gradient (-10, 0, 5.08)  (10, 0, 5.08) Low x and y gradients at center = unfit for MPI
  • 14. Third Approach: Triangular Setup  Place groups of magnets at vertices of equilateral triangle with side length=36cm.  Groups of:  single 1x1” N52 magnets  2 side by side 1x1” N52 magnets  And a 2x2 square of 1x1” N52 magnets  Were used in these simulations  Results from 2x2 square (best results) are shown  Extrusion Height (z-dir) = 60mm
  • 15. Triangular Approach Results  Magnetic fields from each group of magnets were directed at center of triangle – however, this meant that the fields were not evenly opposed  As can be seen in the Y-Z plane view, flux distributions were uneven Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
  • 16. Triangular Flux Density Plots We struggled to plot the gradients along non-axial lines in COMSOL, but given the similar flux density curves for the y-axis field and the field along Cut Lines 3 and 4, we assume that the gradient curves along Cut Lines 3 and 4 were similar to the Y Gradient, as the geometric and magnetic properties of the magnets at each vertex of the triangle were identical. The Y Axis Field and Cut Lines 3 and 4 emanated from magnet groups at the vertices of the triangle Cut Line 3: Cut Line 4:
  • 17. Triangular Magnets Takeaways  Gradients too small  Fields do not cancel effectively at center  R^2 decreasing field effects seem to dominate flux decrease as opposed to true cancellations – theme of all simulations so far = low slope magnetic fields  Unfit for human MPI
  • 18. Two Sets of Opposing Magnets pt. II  Two sets of opposing magnets – taller with different geometric layout  3 magnets in the back and 4 in the front (1”x1” N52)  70cm extrusion
  • 19. Optimized Opposing Magnets Results Y-Z Plane ViewX-Z Plane ViewX-Y Plane View
  • 20. Optimized Opposing Magnets Results (cont.)
  • 21. Optimized Opposing Magnets Results  First Example of actual Free Field “Line” in Spectrum/Arrow plots  Gradient Strength of 0.5 T/m still relatively low – thicker magnets may help?  Gradients of at least 1-2 T/m desired  Optimized opposite magnets do not quite reach desired gradients - quadrupole magnets were attempted next
  • 22. Quadrupole Magnetic Setup  Quadrupole Magnets are a rough approximation to a k=3 Halbach cylinder, leaving no field in the center of the bore  Our quadrupole setup used the same 4+3 1x1” groups of magnets placed on the vertices of an imaginary square of diagonal 36 cm  This setup left ~18.5 cm between each corner magnet – enough room for an average human head to slide in sideways while leaving the FFL approximately at the center of the head  Extrusion height of 70 cm
  • 23. Quadrupole Magnets Results Y-Z Plane ViewX-Z Plane ViewX-Y Plane View  Most clear free field line for permanent magnets  Promising Results – line is very uniform for whole length of magnet – can shorten magnet?
  • 24. Quadrupole Magnets Results  Magnetic Flux density curve look uniform for 30 cm around center of magnet in z direction – x and y flux density curves are nearly identical  Gradient strengths approaching desired levels – could possibly be increased with Iron Yolk?
  • 25. Yolked Quadrupole Setup  Quadrupole magnets are in same arrangement as previous simulation  Iron Yolk placed around Magnets with hole through direction which allows head entrance Cold Rolled (laminated) annealed steel used in simulation with μrelative = 1200 Goal with yolk is to concentrate flux lines within the yolk, ideally increasing gradient Note – yolked simulations for dual opposite magnets in same folder, not as successful
  • 26. Yolked Quadrupole results Y-Z Plane ViewX-Z Plane ViewX-Y Plane View  Slightly more uniform gradients – gradient falls off more slowly in z-dir compared to no yolk
  • 27. Yolked Quadrupole results  Gradients are >1 T/m – possibly high enough for human sized MPI (althought maybe claustrophobic).  Yolk seems to add ~0.3 T/m to gradient at center
  • 28. Electromagnetic Simulations  Not as many simulations done as for static magnetic fields  Copper coils with cross section of 1.25mm were used as inductors  Golay gradient coils were simulated – inverse Helmholtz coils remain a future simulation  Due to COMSOL’s use of Magnetic Potential to calculate Magnetic Flux, the magnetic flux elements calculated in the AC/DC mf module needed to be mapped to a coefficient PDE so that Lagrangian elements could be used to calculate the gradient of the magnetic flux density
  • 29. Golay Coil Setup  8 sets of 17.5cm radius arcs – connected by straight lines as shown. Arc angle is 120 degrees  Current flows in the same direction on the 2 upper inner arcs, and in the opposite direction on the 2 lower inner arcs  Coils excited with 100V at the center of the outside arc
  • 30. Golay Coil Results  All simulations can be found in the mpi_sims folder  Some results:
  • 31. Golay Coil Results  Higher gradients can be created with electromagnets than permanent magnets  Electromagnets are more complex to simulate in COMSOL  Future efforts would go towards mastering the Magnetic Fields interface in COMSOL, and simulating inverted Helmholtz coils