UPDATE OF HIGH RISK PCI . . . IMPELLA vs IABP : INCLUDES THE SHOCK II TRIAL
•Download as PPTX, PDF•
2 likes•965 views
This presentation is an UPDATE of the previous one, related to High Risk PCI in very sick patients compares the Use of IABP versus Impella. Includes the most recents results of the SHOCK II TRIAL published in NEJM August 27, 2012 and presented at the European Society of Cardiology in Munich in the last few days.
Report
Share
Report
Share
Recommended
1 1 quality-principles
This document discusses principles of quality control for registered medicines, non-registered medicines, and counterfeits. It provides background on the EDQM and regulatory frameworks for quality control of registered medicines. For non-registered medicines, it notes the lack of standardized testing methods and importance of developing recognized standards given their traditional origins and limited data. The document also defines counterfeited medicines as illegal and discusses basic areas targeted, including blockbuster and expensive drugs, as well as how, when, and where counterfeiting occurs. It emphasizes the importance of representative sampling and specialized expertise in quality control testing.
sitikiyut KKPI-cafetaria
Dokumen ini merupakan iklan promosi untuk cafetaria di SMK N 1 Sukoharjo. Cafetaria ini dilayani oleh siswa sebagai tempat praktek dan terletak di belakang BCS serta sebelah barat kelas XID/AP 2. Mereka menawarkan berbagai menu makanan dan minuman seperti nasi, gorengan, sate, roti, es, teh dan air mineral dengan harga terjangkau antara Rp. 500 - Rp. 1500. Cafetaria ini menjamin kehalalan mak
Gesture recognition1
The document discusses gesture recognition systems, which allow humans to interact with machines through visible bodily motions or facial expressions. It describes how such systems work by capturing images of gestures via cameras, preprocessing the images, and identifying the gestures. Examples of applications mentioned include sign language recognition, game control through gestures, and using facial expressions for affective computing. Challenges with gesture recognition systems include the cost and difficulty of developing them, as each gesture must be assigned a specific command.
Anteprima modulo 4
Il Modulo che ti proponiamo oggi è dedicato alla scoperta delle "Strategie per gestire le risorse umane" che devono trovare applicazione all'interno dello studio in quanto la capacità dello studio di assicurare alla propria clientela un servizio di qualità che sia al tempo stesso remunerativo è strettamente legata alla professionalità e all'abilità dello staff e della direzione.
Support The Young Innovators Awards Program
The Young Innovators Association (YIA) was founded in 2004 to stimulate research and development (R&D) in Egypt. YIA provides annual awards to fund university student research projects and prototypes. It also offers traineeships to help scientific startups commercialize. YIA has benefited over 3,700 students across 19 universities. Past award winners have developed successful products and startups. However, Egypt spends only 0.25% of its GDP on R&D, ranking 50th out of 53 countries. YIA seeks to address this by raising awareness, encouraging innovation, and connecting researchers to the market. Sponsoring YIA provides benefits like access to talented innovators, brand awareness, and linkages to new
Recommended
1 1 quality-principles
This document discusses principles of quality control for registered medicines, non-registered medicines, and counterfeits. It provides background on the EDQM and regulatory frameworks for quality control of registered medicines. For non-registered medicines, it notes the lack of standardized testing methods and importance of developing recognized standards given their traditional origins and limited data. The document also defines counterfeited medicines as illegal and discusses basic areas targeted, including blockbuster and expensive drugs, as well as how, when, and where counterfeiting occurs. It emphasizes the importance of representative sampling and specialized expertise in quality control testing.
sitikiyut KKPI-cafetaria
Dokumen ini merupakan iklan promosi untuk cafetaria di SMK N 1 Sukoharjo. Cafetaria ini dilayani oleh siswa sebagai tempat praktek dan terletak di belakang BCS serta sebelah barat kelas XID/AP 2. Mereka menawarkan berbagai menu makanan dan minuman seperti nasi, gorengan, sate, roti, es, teh dan air mineral dengan harga terjangkau antara Rp. 500 - Rp. 1500. Cafetaria ini menjamin kehalalan mak
Gesture recognition1
The document discusses gesture recognition systems, which allow humans to interact with machines through visible bodily motions or facial expressions. It describes how such systems work by capturing images of gestures via cameras, preprocessing the images, and identifying the gestures. Examples of applications mentioned include sign language recognition, game control through gestures, and using facial expressions for affective computing. Challenges with gesture recognition systems include the cost and difficulty of developing them, as each gesture must be assigned a specific command.
Anteprima modulo 4
Il Modulo che ti proponiamo oggi è dedicato alla scoperta delle "Strategie per gestire le risorse umane" che devono trovare applicazione all'interno dello studio in quanto la capacità dello studio di assicurare alla propria clientela un servizio di qualità che sia al tempo stesso remunerativo è strettamente legata alla professionalità e all'abilità dello staff e della direzione.
Support The Young Innovators Awards Program
The Young Innovators Association (YIA) was founded in 2004 to stimulate research and development (R&D) in Egypt. YIA provides annual awards to fund university student research projects and prototypes. It also offers traineeships to help scientific startups commercialize. YIA has benefited over 3,700 students across 19 universities. Past award winners have developed successful products and startups. However, Egypt spends only 0.25% of its GDP on R&D, ranking 50th out of 53 countries. YIA seeks to address this by raising awareness, encouraging innovation, and connecting researchers to the market. Sponsoring YIA provides benefits like access to talented innovators, brand awareness, and linkages to new
Ge Careers How To Apply
The GE application process involves joining the GE Talent Community by creating a profile, applying to jobs, and submitting a resume and other application materials. Applicants can search for jobs by keyword, title, location, or function, apply to opportunities, and check the status of their applications online. Returning applicants can easily apply to more jobs and edit their profiles as needed.
Virtual + Magazine (2012 vEN)
The document describes ISUS, an online language learning platform that connects learners with trainers from around the world for personalized instruction. Learners are assigned a dedicated trainer who analyzes their needs, sets goals, and guides them through engaging one-on-one programs. ISUS also offers an e-magazine for self-study that features interactive articles, videos, and activities covering business English, current events, and other topics. The platform aims to make language learning effective and convenient through an intuitive interface and flexible online or blended options.
FloBoard SlideShare
FloBoard provides visual process management and shadow boards to help organizations track tasks, improve quality assurance, and coordinate activities. Their magnetic boards allow tasks, personnel, assets and other items to be moved and tracked visually. Case studies describe boards designed for maintenance tracking, traffic management scheduling, production line safety, and sales lead tracking that helped different companies work more efficiently.
White Paper Employee Retention
This document discusses strategies for employee retention. It outlines tools to determine which employees to retain, such as a uniqueness grid to identify employees with specialized skills. It also discusses how to treat exiting employees respectfully to maintain trust with remaining employees. Finally, it recommends establishing retention policies focused on communication, recognition, and culture fit to motivate employees to stay.
GE Industial Internet Vision Paper
The document discusses three waves of innovation:
1) The Industrial Revolution which increased productivity through mechanization.
2) The Internet Revolution which further increased productivity through computing and communication technologies.
3) The emerging Third Wave called the Industrial Internet, which connects intelligent machines via sensors and analytics, combining the advances of the prior two revolutions. This convergence holds potential for significant productivity gains across industries through improved efficiency.
Edema tx
This document defines key terms related to substance use disorders and provides diagnostic criteria. It discusses dependence, abuse, intoxication, withdrawal, and tolerance. Dependence involves impaired control over substance use and continuation despite adverse consequences. Abuse involves harmful use with impairment. The DSM-IV criteria for substance abuse, withdrawal, and dependence are outlined. Factors influencing substance use disorders include genetics, neurochemistry, peer pressure, and comorbid mental health conditions. Treatment aims to manage withdrawal and facilitate long-term behavioral change through various interventions.
Photosheet slideshow
This document provides details on 29 outdoor advertising locations in West Virginia, including coordinates and structure descriptions. The locations span major interstates and highways from Parkersburg to Charleston. Each entry includes the location's daily traffic count, coordinates, structure type (e.g. double-stacked steel monopole), number of faces, and face sizes. Contact information is provided for Heather Perkins, VP of Sales and Marketing at Hicks Outdoor Advertising.
Anteprima modulo 8
Il Modulo che ti proponiamo oggi è dedicato alla "Pianificazione della successione" e viene descritto il modo in cui è possibile pianificare la successione per consentire un ritiro programmato dall’attività dello studio assieme alle strategie che è possibile adottare in tale contesto, affrontando temi quali la valutazione dello studio e la definizione di un prezzo per la sua cessione, o l’opportunità di optare per una fusione o un’acquisizione dall’interno o dall’esterno.
Mike baker r ecuerda
Este documento enfatiza la importancia de recordar vivir la vida plenamente y disfrutar cada momento como si fuera el último. Recuerda ser feliz y aprovechar cada segundo de la única vida que se tiene.
TROMBOLISIS INTRA-ARTERIAL EN EVENTO CEREBRAL VASCULAR ISQUEMICO AGUDO
NEUROINTERVENCIONISMO
Revisión de los Estudios de Trombolisis Intra-Arterial Superselectiva en el Tratamiento del Evento Cerebral Vascular Isquémico Agudo ( Mayo 2012 )
ESTADO DEL ARTE: TERAPIA ENDOVASCULAR BASADA EN CATETERES PARA EL EVENTO CER...
ESTADO DEL ARTE: TERAPIA ENDOVASCULAR BASADA EN CATETERES PARA EL EVENTO CER...Dr. Jose L. Assad-Morell
Actualización de los Estudios de Trombectomía Mecánica para la Recanalización de las Oclusiones de las Grandes Arterias Cerebrales en el Evento Cerebral Vascular Isquémico Agudo. La Revisión termina el 26 de Agosto, 2012 .-SINDROMES AORTICOS AGUDOS
Review of the ACUTE AORTIC SYNDROMES with major emphasis over Acute Type B Aortic Dissection and a brief Analysis of the different Trials including IRAD, INSTEAD, VALOR, VIRTUE and STABLE.-
ISCHEMIC MITRAL VALVE DISEASE: THERAPEUTIC CONUNDRUM
THIS A REVIEW OF THE MEDICAL COMPLEXITIES RELATED TO THE THERAPEUTIC MANAGEMENT OF ISCHEMIC MITRAL VALVE INSUFFICIENCY
ABDOMINAL AORTIC ANEURYSMS :SMALL AND LARGE
The document discusses the benefits of regular exercise for both physical and mental health. It notes that exercise can help reduce the risk of diseases like heart disease, diabetes, and some cancers. The document recommends that adults get at least 150 minutes of moderate exercise or 75 minutes of vigorous exercise per week to experience these health benefits.
INTERVENTIONAL TECHNIQUES IN CHRONIC TOTAL OCCLUSIONS
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
FEMORAL ARTERY : STATE OF THE ART OF ENDOVASCULAR THERAPY
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help boost feelings of calmness, happiness and focus.
STENT CAROTIDEO : COMO PREVENIR Y MANEJAR LAS COMPLICACIONES
Revisión exhaustiva de las complicaciones del stent carotídeo : indicaciones y sugerencias de como prevenir las complicaciones y como tratarlas cuando estas ocurren .-
CAROTID STENTING : TECHNICAL TIPS & TRICKS
This presentation helps to understand the Technical Tips and Tricks useful at the time of performing Carotid Stenting
DEEP VEIN THROMBOSIS & CATHETER DIRECTED MECHANICAL THROMBECTOMY
This presentation is directed to show the Catheter Directed Mechanical Thrombectomy in the Treatment of Iliofemoral Deep Vein Thrombosis ( includes analysis of recent clinical trials )
More Related Content
Viewers also liked
Ge Careers How To Apply
The GE application process involves joining the GE Talent Community by creating a profile, applying to jobs, and submitting a resume and other application materials. Applicants can search for jobs by keyword, title, location, or function, apply to opportunities, and check the status of their applications online. Returning applicants can easily apply to more jobs and edit their profiles as needed.
Virtual + Magazine (2012 vEN)
The document describes ISUS, an online language learning platform that connects learners with trainers from around the world for personalized instruction. Learners are assigned a dedicated trainer who analyzes their needs, sets goals, and guides them through engaging one-on-one programs. ISUS also offers an e-magazine for self-study that features interactive articles, videos, and activities covering business English, current events, and other topics. The platform aims to make language learning effective and convenient through an intuitive interface and flexible online or blended options.
FloBoard SlideShare
FloBoard provides visual process management and shadow boards to help organizations track tasks, improve quality assurance, and coordinate activities. Their magnetic boards allow tasks, personnel, assets and other items to be moved and tracked visually. Case studies describe boards designed for maintenance tracking, traffic management scheduling, production line safety, and sales lead tracking that helped different companies work more efficiently.
White Paper Employee Retention
This document discusses strategies for employee retention. It outlines tools to determine which employees to retain, such as a uniqueness grid to identify employees with specialized skills. It also discusses how to treat exiting employees respectfully to maintain trust with remaining employees. Finally, it recommends establishing retention policies focused on communication, recognition, and culture fit to motivate employees to stay.
GE Industial Internet Vision Paper
The document discusses three waves of innovation:
1) The Industrial Revolution which increased productivity through mechanization.
2) The Internet Revolution which further increased productivity through computing and communication technologies.
3) The emerging Third Wave called the Industrial Internet, which connects intelligent machines via sensors and analytics, combining the advances of the prior two revolutions. This convergence holds potential for significant productivity gains across industries through improved efficiency.
Edema tx
This document defines key terms related to substance use disorders and provides diagnostic criteria. It discusses dependence, abuse, intoxication, withdrawal, and tolerance. Dependence involves impaired control over substance use and continuation despite adverse consequences. Abuse involves harmful use with impairment. The DSM-IV criteria for substance abuse, withdrawal, and dependence are outlined. Factors influencing substance use disorders include genetics, neurochemistry, peer pressure, and comorbid mental health conditions. Treatment aims to manage withdrawal and facilitate long-term behavioral change through various interventions.
Photosheet slideshow
This document provides details on 29 outdoor advertising locations in West Virginia, including coordinates and structure descriptions. The locations span major interstates and highways from Parkersburg to Charleston. Each entry includes the location's daily traffic count, coordinates, structure type (e.g. double-stacked steel monopole), number of faces, and face sizes. Contact information is provided for Heather Perkins, VP of Sales and Marketing at Hicks Outdoor Advertising.
Anteprima modulo 8
Il Modulo che ti proponiamo oggi è dedicato alla "Pianificazione della successione" e viene descritto il modo in cui è possibile pianificare la successione per consentire un ritiro programmato dall’attività dello studio assieme alle strategie che è possibile adottare in tale contesto, affrontando temi quali la valutazione dello studio e la definizione di un prezzo per la sua cessione, o l’opportunità di optare per una fusione o un’acquisizione dall’interno o dall’esterno.
Mike baker r ecuerda
Este documento enfatiza la importancia de recordar vivir la vida plenamente y disfrutar cada momento como si fuera el último. Recuerda ser feliz y aprovechar cada segundo de la única vida que se tiene.
Viewers also liked (12)
More from Dr. Jose L. Assad-Morell
TROMBOLISIS INTRA-ARTERIAL EN EVENTO CEREBRAL VASCULAR ISQUEMICO AGUDO
NEUROINTERVENCIONISMO
Revisión de los Estudios de Trombolisis Intra-Arterial Superselectiva en el Tratamiento del Evento Cerebral Vascular Isquémico Agudo ( Mayo 2012 )
ESTADO DEL ARTE: TERAPIA ENDOVASCULAR BASADA EN CATETERES PARA EL EVENTO CER...
ESTADO DEL ARTE: TERAPIA ENDOVASCULAR BASADA EN CATETERES PARA EL EVENTO CER...Dr. Jose L. Assad-Morell
Actualización de los Estudios de Trombectomía Mecánica para la Recanalización de las Oclusiones de las Grandes Arterias Cerebrales en el Evento Cerebral Vascular Isquémico Agudo. La Revisión termina el 26 de Agosto, 2012 .-SINDROMES AORTICOS AGUDOS
Review of the ACUTE AORTIC SYNDROMES with major emphasis over Acute Type B Aortic Dissection and a brief Analysis of the different Trials including IRAD, INSTEAD, VALOR, VIRTUE and STABLE.-
ISCHEMIC MITRAL VALVE DISEASE: THERAPEUTIC CONUNDRUM
THIS A REVIEW OF THE MEDICAL COMPLEXITIES RELATED TO THE THERAPEUTIC MANAGEMENT OF ISCHEMIC MITRAL VALVE INSUFFICIENCY
ABDOMINAL AORTIC ANEURYSMS :SMALL AND LARGE
The document discusses the benefits of regular exercise for both physical and mental health. It notes that exercise can help reduce the risk of diseases like heart disease, diabetes, and some cancers. The document recommends that adults get at least 150 minutes of moderate exercise or 75 minutes of vigorous exercise per week to experience these health benefits.
INTERVENTIONAL TECHNIQUES IN CHRONIC TOTAL OCCLUSIONS
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
FEMORAL ARTERY : STATE OF THE ART OF ENDOVASCULAR THERAPY
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help boost feelings of calmness, happiness and focus.
STENT CAROTIDEO : COMO PREVENIR Y MANEJAR LAS COMPLICACIONES
Revisión exhaustiva de las complicaciones del stent carotídeo : indicaciones y sugerencias de como prevenir las complicaciones y como tratarlas cuando estas ocurren .-
CAROTID STENTING : TECHNICAL TIPS & TRICKS
This presentation helps to understand the Technical Tips and Tricks useful at the time of performing Carotid Stenting
DEEP VEIN THROMBOSIS & CATHETER DIRECTED MECHANICAL THROMBECTOMY
This presentation is directed to show the Catheter Directed Mechanical Thrombectomy in the Treatment of Iliofemoral Deep Vein Thrombosis ( includes analysis of recent clinical trials )
Left main coronary artery
Este documento discute la revascularización del tronco coronario izquierdo no protegido (TCI-NP) mediante cirugía de puentes coronarios versus intervención coronaria percutánea (ICP) con stents liberadores de fármacos. Los lineamientos actuales recomiendan la cirugía como tratamiento de primera línea para el TCI-NP. Sin embargo, varios estudios recientes muestran que la ICP con stents liberadores de fármacos puede tratar con éxito lesiones del TCI-NP con bajas tasas de mortalidad, infart
Endovascular Treatment of Critical Limb Ischemia
Describes the definition of critical limb ischemia, main Trials over the last 2 years and different techniques for critical limb ischemia rescue.- Name of the game is the salvage of the extremity !!!
Therapeutic window for stroke management
ACUTE STROKE
Therapeutic Window for Stroke Management:
from Logic to Logistics for Providing Improved Health Care
More from Dr. Jose L. Assad-Morell (13)
TROMBOLISIS INTRA-ARTERIAL EN EVENTO CEREBRAL VASCULAR ISQUEMICO AGUDO
TROMBOLISIS INTRA-ARTERIAL EN EVENTO CEREBRAL VASCULAR ISQUEMICO AGUDO
ESTADO DEL ARTE: TERAPIA ENDOVASCULAR BASADA EN CATETERES PARA EL EVENTO CER...
ESTADO DEL ARTE: TERAPIA ENDOVASCULAR BASADA EN CATETERES PARA EL EVENTO CER...
ISCHEMIC MITRAL VALVE DISEASE: THERAPEUTIC CONUNDRUM
ISCHEMIC MITRAL VALVE DISEASE: THERAPEUTIC CONUNDRUM
INTERVENTIONAL TECHNIQUES IN CHRONIC TOTAL OCCLUSIONS
INTERVENTIONAL TECHNIQUES IN CHRONIC TOTAL OCCLUSIONS
FEMORAL ARTERY : STATE OF THE ART OF ENDOVASCULAR THERAPY
FEMORAL ARTERY : STATE OF THE ART OF ENDOVASCULAR THERAPY
STENT CAROTIDEO : COMO PREVENIR Y MANEJAR LAS COMPLICACIONES
STENT CAROTIDEO : COMO PREVENIR Y MANEJAR LAS COMPLICACIONES
DEEP VEIN THROMBOSIS & CATHETER DIRECTED MECHANICAL THROMBECTOMY
DEEP VEIN THROMBOSIS & CATHETER DIRECTED MECHANICAL THROMBECTOMY
Recently uploaded
10 Benefits an EPCR Software should Bring to EMS Organizations
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
CLEAR ALIGNER THERAPY IN ORTHODONTICS .pptx
Dr. ZANAB FARHEEN FAYAZ ,MDS(ORTHODONTICS & DENTOFACIAL ORTHOPEDICS ).
Know the difference between Endodontics and Orthodontics.
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
What are the different types of Dental implants.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Fallopian tube blockage may cause female infertility. For treatment, herbal medicine Fuyan Pill can be a solution.
SENSORY NEEDS B.SC. NURSING SEMESTER II.
Sensation is the neurological process by which we become aware of surrounding environment.
Skin Diseases That Happen During Summer.
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
une 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Nano-gold for Cancer Therapy chemistry investigatory project
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
This quiz was conducted as a promotional event for the 2024 Annual Meet of Kerala Chapter of API.
More than 20 participants took part everyday !
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Recently uploaded (20)
10 Benefits an EPCR Software should Bring to EMS Organizations
10 Benefits an EPCR Software should Bring to EMS Organizations
Know the difference between Endodontics and Orthodontics.
Know the difference between Endodontics and Orthodontics.
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis - Definition , Evaluation and Management .pdf
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Nano-gold for Cancer Therapy chemistry investigatory project
Nano-gold for Cancer Therapy chemistry investigatory project
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf