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Development of a Health Geomatics
analysis framework to evaluate cardiac
arrests in Lombardy.
New information for decision-making
POLITECNICO DI MILANO
Marelli G1, Munoz C2, Brambilla P3, Sesana G3, Pagliosa A3,
Brovelli M 2, Caiani EG 1
1Eletronics, Information and Biomedical Eng. Dpt., Politecnico di Milano, Milan, Italy
2Environmental and Civil Eng., Politecnico di Milano, Milan, Italy
3Azienda Regionale Emergenza Urgenza (AREU), Milan, Italy
Introduction: Cardiac Arrest (CA)
POLITECNICO DI MILANO
Cardiac Arrest (CA) represents
a global major health problem:
in Italy, one over 1000
inhabitants loses his/her life
every year.
temporary
malfunction of
the cardiac
electric
conduction
system
arrhythmias VF CA
Car accidents: 0.06/1000
AIDS : 0.02/1000
enrico.caiani@polimi.it
Introduction: Cardiac Arrest (CA)
POLITECNICO DI MILANO
Consequences can be very
serious, as after 5-6
minutes brain cells, if not
opportunely oxigenated,
start dying.
Outcome from out-of-hospital CA (OHCA) remains poor: only
10.8% of adult patients with non-traumatic cardiac arrest who
have received resuscitative efforts from emergency medical
services (EMS) survive to hospital discharge [AHA Guidelines
Update 2015]
enrico.caiani@polimi.it
Introduction: Chain of Survival
POLITECNICO DI MILANO
Start immediately the actions prescribed in the Chain of
Survival.
enrico.caiani@polimi.it
Introduction: Cardiac Defibrillation
POLITECNICO DI MILANO
A proper distribution of AED on the territory is essential for
possible lay rescuers to access it when witnessing a CA, thus
increasing survival rate.
enrico.caiani@polimi.it
Aims of the work
POLITECNICO DI MILANO
• to analyze by health
geomatics techniques
the 2015 CA and
AED database
relevant to the
Lombardy Region in
Italy
• to retrospectively
focus on CA events
distribution and AED
coverage of the city
of Milan
We hypothesized that
approaches based on
health geomatics
applied to CA could
provide useful
information about the
distribution of events
and the definition of
strategies for
relocating
emergency
resources on a
specific territory.
enrico.caiani@polimi.it
Methods:Health Geomatics
POLITECNICO DI MILANO
Health Geomatics: gathering, storing, processing, and
delivering geographic information related to health through a
Geographical Information System
Location can influence
health (Hyppocrates, III b.c.)
John Snow
enrico.caiani@polimi.it
Methods: Cardiac Arrests in Lombardy in 2015
POLITECNICO DI MILANO
Fields in the database:
• Age and sex of the patient
• Geolocalization and date/time of the call
• Arrival time of the emergency medical services
• PCR: yes/no
• Result of PCR
• Utilized AED: yes/no
• Result of the emergency care
Geographical
information converted
into the WGS 84 -
UTM 32 Nord
coordinate reference
system
enrico.caiani@polimi.it
Methods: Open Access data relevant to Lombardy
POLITECNICO DI MILANO
Resident population
data for all towns in
Lombardy at 31/12/15,
divided by sex and age
Position of 6212 AED
in Lombardy
Cartography of towns,
provinces and
healthcare districts
(Aziende Sanitarie
Locali, ASL)
Open streets and
intersections
enrico.caiani@polimi.it
Methods: Merging and summarizing information
POLITECNICO DI MILANO
Chosing the proper subdivision of the territory for data merging:
1530 Towns
8 actual healthcare
discricts (ATS)
15 old healthcare
districts (ASL)
enrico.caiani@polimi.it
Results: Mapping CA in Lombardy
POLITECNICO DI MILANO
CA at home CA outside
At
home
87%
Out
13%
10686 CA events
enrico.caiani@polimi.it
Results: Mapping AED in Lombardy
POLITECNICO DI MILANO
ASL Code ASL Name # AED POPULATION
100*
DAE/POPULATION
(%)
1 Bergamo 806 1108298 0.073
2 Brescia 951 1163407 0.082
3 Como 426 599654 0.071
4 Cremona 168 360444 0.047
5 Lecco 202 339254 0.060
6 Lodi 148 236756 0.063
7 Mantova 252 412868 0.061
8 Milano 642 1615775 0.040
9 Milano 1 559 952855 0.059
10 Milano 2 341 632536 0.054
11 Monza e della Brianza 557 866076 0.064
12 Pavia 393 547926 0.072
13 Sondrio 117 181712 0.064
14 Varese 437 890090 0.049
15 Vallecamonica-Sebino 125 100698 0.124
Non-uniform distribution in
respect to the number of
residents, with a minimum of
4‰ (ASL 8) to a maximum of
10 ‰ (ASL 15).
Further analysis on
CA events distribution
and AED potential
coverage using
isochrones
enrico.caiani@polimi.it
Methods: Isochrones computation
POLITECNICO DI MILANO
Isochrones are temporal lines drawn on a map
connecting points that can be reached at the same
time from the same starting point.
RADIAL
REALISTIC:
real path on existing roads
enrico.caiani@polimi.it
POLITECNICO DI MILANO
Methods: Isochrones computation
DAE position
Closest road intersection
Network analysis: Milan’s
streets were considered as a
graph, formed by edges (the
streets), and nodes (their
intersection), with AED
position approximated by the
closest node.
15 Weight for each
edge: distance
PostgreSQL (http://www.postgresql.org) with pgRouting (http://pgrouting.org/)
and PostGIS https://postgis.net) extensions were used.
Realistic isochrones centered in each AED position, using as
parameter the distance that can be traveled in a roundtrip of 6
minutes, at three different walk speeds: 1.5 m/s (270 m), 2 m/s
(360 m) and 3 m/s (540 m).
enrico.caiani@polimi.it
POLITECNICO DI MILANO
Results: Milan territory covered by AED
3 m/s speed
realistic isochrones
Territory covered:
1.5 m/s  3.9%
2 m/s  7.1%
3 m/s  14.2%
4005 CAs events:
3556 at home, 449 outside
Median time of arrival:
9 min (7;12).
AED used in 1.5% cases
Not used: 45.8%
Unknown: 52.7%
Retrospective graphical analysis:
• 57% of CAs at home and 53% of CAs
outside potentially covered by one AED
within 540 m
• AED effectively used by laymen in
0.7% and 2% of cases only, respectively.
enrico.caiani@polimi.it
Limitations
POLITECNICO DI MILANO
• In isochrones computation:
- complete accuracy of the Milan road network topology
not guaranteed, as open data
- approximation of AED position with the closest node
- only ground level considered
• In available information:
- Missing data on AED utilization in >50% of CA events
- Missing data on >1 laymen presence at CA location
- AED inaccessible in certain hours not considered
enrico.caiani@polimi.it
Conclusions
POLITECNICO DI MILANO
Combined with the retrospective analysis of the effective
use of AED in CAs in Milan city in 2015, it showed that
AEDs were very rarely used by laymen, while waiting for
ambulance arrival, besides their potential availability.
Health geomatics approaches represent an additional tool
to assess the incidence of a disease on a specific territory,
and to evaluate the distribution of resources, useful for
designing spatial optimization strategies.
New strategies are needed to improve AEDs coverage of
the territory, citizen’s awareness about AEDs location and
how to use them, and active tools to alert possible nearby
rescuers.
enrico.caiani@polimi.it
Join us!
Acknowledgements
European Union H2020-TWINN-2015 (project
“Linking excellence in biomedical knowledge and
computational intelligence research for
personalized management of Cardio Vascular
Disease within Personalized Health Care”).
enrico.caiani@polimi.it

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Health geomatics framework to evaluate cardiac arrests in Lombardy - new tools for decision making

  • 1. Development of a Health Geomatics analysis framework to evaluate cardiac arrests in Lombardy. New information for decision-making POLITECNICO DI MILANO Marelli G1, Munoz C2, Brambilla P3, Sesana G3, Pagliosa A3, Brovelli M 2, Caiani EG 1 1Eletronics, Information and Biomedical Eng. Dpt., Politecnico di Milano, Milan, Italy 2Environmental and Civil Eng., Politecnico di Milano, Milan, Italy 3Azienda Regionale Emergenza Urgenza (AREU), Milan, Italy
  • 2. Introduction: Cardiac Arrest (CA) POLITECNICO DI MILANO Cardiac Arrest (CA) represents a global major health problem: in Italy, one over 1000 inhabitants loses his/her life every year. temporary malfunction of the cardiac electric conduction system arrhythmias VF CA Car accidents: 0.06/1000 AIDS : 0.02/1000 enrico.caiani@polimi.it
  • 3. Introduction: Cardiac Arrest (CA) POLITECNICO DI MILANO Consequences can be very serious, as after 5-6 minutes brain cells, if not opportunely oxigenated, start dying. Outcome from out-of-hospital CA (OHCA) remains poor: only 10.8% of adult patients with non-traumatic cardiac arrest who have received resuscitative efforts from emergency medical services (EMS) survive to hospital discharge [AHA Guidelines Update 2015] enrico.caiani@polimi.it
  • 4. Introduction: Chain of Survival POLITECNICO DI MILANO Start immediately the actions prescribed in the Chain of Survival. enrico.caiani@polimi.it
  • 5. Introduction: Cardiac Defibrillation POLITECNICO DI MILANO A proper distribution of AED on the territory is essential for possible lay rescuers to access it when witnessing a CA, thus increasing survival rate. enrico.caiani@polimi.it
  • 6. Aims of the work POLITECNICO DI MILANO • to analyze by health geomatics techniques the 2015 CA and AED database relevant to the Lombardy Region in Italy • to retrospectively focus on CA events distribution and AED coverage of the city of Milan We hypothesized that approaches based on health geomatics applied to CA could provide useful information about the distribution of events and the definition of strategies for relocating emergency resources on a specific territory. enrico.caiani@polimi.it
  • 7. Methods:Health Geomatics POLITECNICO DI MILANO Health Geomatics: gathering, storing, processing, and delivering geographic information related to health through a Geographical Information System Location can influence health (Hyppocrates, III b.c.) John Snow enrico.caiani@polimi.it
  • 8. Methods: Cardiac Arrests in Lombardy in 2015 POLITECNICO DI MILANO Fields in the database: • Age and sex of the patient • Geolocalization and date/time of the call • Arrival time of the emergency medical services • PCR: yes/no • Result of PCR • Utilized AED: yes/no • Result of the emergency care Geographical information converted into the WGS 84 - UTM 32 Nord coordinate reference system enrico.caiani@polimi.it
  • 9. Methods: Open Access data relevant to Lombardy POLITECNICO DI MILANO Resident population data for all towns in Lombardy at 31/12/15, divided by sex and age Position of 6212 AED in Lombardy Cartography of towns, provinces and healthcare districts (Aziende Sanitarie Locali, ASL) Open streets and intersections enrico.caiani@polimi.it
  • 10. Methods: Merging and summarizing information POLITECNICO DI MILANO Chosing the proper subdivision of the territory for data merging: 1530 Towns 8 actual healthcare discricts (ATS) 15 old healthcare districts (ASL) enrico.caiani@polimi.it
  • 11. Results: Mapping CA in Lombardy POLITECNICO DI MILANO CA at home CA outside At home 87% Out 13% 10686 CA events enrico.caiani@polimi.it
  • 12. Results: Mapping AED in Lombardy POLITECNICO DI MILANO ASL Code ASL Name # AED POPULATION 100* DAE/POPULATION (%) 1 Bergamo 806 1108298 0.073 2 Brescia 951 1163407 0.082 3 Como 426 599654 0.071 4 Cremona 168 360444 0.047 5 Lecco 202 339254 0.060 6 Lodi 148 236756 0.063 7 Mantova 252 412868 0.061 8 Milano 642 1615775 0.040 9 Milano 1 559 952855 0.059 10 Milano 2 341 632536 0.054 11 Monza e della Brianza 557 866076 0.064 12 Pavia 393 547926 0.072 13 Sondrio 117 181712 0.064 14 Varese 437 890090 0.049 15 Vallecamonica-Sebino 125 100698 0.124 Non-uniform distribution in respect to the number of residents, with a minimum of 4‰ (ASL 8) to a maximum of 10 ‰ (ASL 15). Further analysis on CA events distribution and AED potential coverage using isochrones enrico.caiani@polimi.it
  • 13. Methods: Isochrones computation POLITECNICO DI MILANO Isochrones are temporal lines drawn on a map connecting points that can be reached at the same time from the same starting point. RADIAL REALISTIC: real path on existing roads enrico.caiani@polimi.it
  • 14. POLITECNICO DI MILANO Methods: Isochrones computation DAE position Closest road intersection Network analysis: Milan’s streets were considered as a graph, formed by edges (the streets), and nodes (their intersection), with AED position approximated by the closest node. 15 Weight for each edge: distance PostgreSQL (http://www.postgresql.org) with pgRouting (http://pgrouting.org/) and PostGIS https://postgis.net) extensions were used. Realistic isochrones centered in each AED position, using as parameter the distance that can be traveled in a roundtrip of 6 minutes, at three different walk speeds: 1.5 m/s (270 m), 2 m/s (360 m) and 3 m/s (540 m). enrico.caiani@polimi.it
  • 15. POLITECNICO DI MILANO Results: Milan territory covered by AED 3 m/s speed realistic isochrones Territory covered: 1.5 m/s  3.9% 2 m/s  7.1% 3 m/s  14.2% 4005 CAs events: 3556 at home, 449 outside Median time of arrival: 9 min (7;12). AED used in 1.5% cases Not used: 45.8% Unknown: 52.7% Retrospective graphical analysis: • 57% of CAs at home and 53% of CAs outside potentially covered by one AED within 540 m • AED effectively used by laymen in 0.7% and 2% of cases only, respectively. enrico.caiani@polimi.it
  • 16. Limitations POLITECNICO DI MILANO • In isochrones computation: - complete accuracy of the Milan road network topology not guaranteed, as open data - approximation of AED position with the closest node - only ground level considered • In available information: - Missing data on AED utilization in >50% of CA events - Missing data on >1 laymen presence at CA location - AED inaccessible in certain hours not considered enrico.caiani@polimi.it
  • 17. Conclusions POLITECNICO DI MILANO Combined with the retrospective analysis of the effective use of AED in CAs in Milan city in 2015, it showed that AEDs were very rarely used by laymen, while waiting for ambulance arrival, besides their potential availability. Health geomatics approaches represent an additional tool to assess the incidence of a disease on a specific territory, and to evaluate the distribution of resources, useful for designing spatial optimization strategies. New strategies are needed to improve AEDs coverage of the territory, citizen’s awareness about AEDs location and how to use them, and active tools to alert possible nearby rescuers. enrico.caiani@polimi.it
  • 18. Join us! Acknowledgements European Union H2020-TWINN-2015 (project “Linking excellence in biomedical knowledge and computational intelligence research for personalized management of Cardio Vascular Disease within Personalized Health Care”). enrico.caiani@polimi.it