This document discusses using approximations of gram matrices to reduce computational complexity for GMMN-based speech synthesis. It summarizes conventional local approximation and proposes using random Fourier features and clustering to select minibatches. An experiment compares these methods on a Japanese speech corpus, finding that RFF and clustering-based minibatch selection improved diversity of synthesized speech samples over baselines, while maintaining naturalness. The document concludes future work could employ sequence modeling, more data, and better evaluation of sampling-based text-to-speech.
In this work, we propose to apply trust region optimization to deep reinforcement
learning using a recently proposed Kronecker-factored approximation to
the curvature. We extend the framework of natural policy gradient and propose
to optimize both the actor and the critic using Kronecker-factored approximate
curvature (K-FAC) with trust region; hence we call our method Actor Critic using
Kronecker-Factored Trust Region (ACKTR). To the best of our knowledge, this
is the first scalable trust region natural gradient method for actor-critic methods.
It is also a method that learns non-trivial tasks in continuous control as well as
discrete control policies directly from raw pixel inputs. We tested our approach
across discrete domains in Atari games as well as continuous domains in the MuJoCo
environment. With the proposed methods, we are able to achieve higher
rewards and a 2- to 3-fold improvement in sample efficiency on average, compared
to previous state-of-the-art on-policy actor-critic methods. Code is available at
https://github.com/openai/baselines.
Research Inventy : International Journal of Engineering and Science is published by the group of young academic and industrial researchers with 12 Issues per year. It is an online as well as print version open access journal that provides rapid publication (monthly) of articles in all areas of the subject such as: civil, mechanical, chemical, electronic and computer engineering as well as production and information technology. The Journal welcomes the submission of manuscripts that meet the general criteria of significance and scientific excellence. Papers will be published by rapid process within 20 days after acceptance and peer review process takes only 7 days. All articles published in Research Inventy will be peer-reviewed.
EE402B Radio Systems and Personal Communication Networks notesHaris Hassan
Programmes in which available:
Masters of Engineering - Electrical and Electronic
Engineering. Masters of Engineering - Electronic
Engineering and Computer Science. Master of Science -
Communication Systems and Wireless Networking.
Master of Science - Smart Telecom and Sensing
Networks. Master of Science - Photonic Integrated
Circuits, Sensors and Networks.
In this work, we propose to apply trust region optimization to deep reinforcement
learning using a recently proposed Kronecker-factored approximation to
the curvature. We extend the framework of natural policy gradient and propose
to optimize both the actor and the critic using Kronecker-factored approximate
curvature (K-FAC) with trust region; hence we call our method Actor Critic using
Kronecker-Factored Trust Region (ACKTR). To the best of our knowledge, this
is the first scalable trust region natural gradient method for actor-critic methods.
It is also a method that learns non-trivial tasks in continuous control as well as
discrete control policies directly from raw pixel inputs. We tested our approach
across discrete domains in Atari games as well as continuous domains in the MuJoCo
environment. With the proposed methods, we are able to achieve higher
rewards and a 2- to 3-fold improvement in sample efficiency on average, compared
to previous state-of-the-art on-policy actor-critic methods. Code is available at
https://github.com/openai/baselines.
Research Inventy : International Journal of Engineering and Science is published by the group of young academic and industrial researchers with 12 Issues per year. It is an online as well as print version open access journal that provides rapid publication (monthly) of articles in all areas of the subject such as: civil, mechanical, chemical, electronic and computer engineering as well as production and information technology. The Journal welcomes the submission of manuscripts that meet the general criteria of significance and scientific excellence. Papers will be published by rapid process within 20 days after acceptance and peer review process takes only 7 days. All articles published in Research Inventy will be peer-reviewed.
EE402B Radio Systems and Personal Communication Networks notesHaris Hassan
Programmes in which available:
Masters of Engineering - Electrical and Electronic
Engineering. Masters of Engineering - Electronic
Engineering and Computer Science. Master of Science -
Communication Systems and Wireless Networking.
Master of Science - Smart Telecom and Sensing
Networks. Master of Science - Photonic Integrated
Circuits, Sensors and Networks.
Performance Analysis of PAPR Reduction in MIMO-OFDMIJARBEST JOURNAL
Authors: Jayaraman.G1, VeeraKumar K2, Selvakani.S3
Abstract— In communication system, it is aimed to provide highest possible
transmission rate at the lowest possible power and with the least possible noise. MIMOOFDM
has been chosen for high data rate communications and widely deployed in many
wireless communication standards. The major drawback in OFDM signal transmission is
high PAPR. In previous, use clipping technique to tackle this problem. In this paper, use
EM-GAMP algorithm to reduce PAPR in considerable amount.
This presentation contains the concepts of frequency domain filtering of digital images. This includes the different kinds of filters used in frequency domain analysis,their characteristics and various phenomenon such as aliasing, inverse filtering etc. The contents are taken from variety of sources like Gonzalez image processing book, Pratt image processing book and some on-line resources.
DFA minimization algorithms in map reduceIraj Hedayati
Explaining implementation and analysis of two well known DFA minimisation algorithms namely Morore and Hopcroft, in Map Reduce using Hadoop. Cost analysis and complexity are described.
Please follow this link: http://spectrum.library.concordia.ca/980838/
Joint Compensation of CIM3 and I/Q Imbalance in the Up-conversion Mixer with ...Ealwan Lee
Slides used during the lecture in RFIT-2017 on Aug 31, 2017(Seoul, Korea)
Refined Model for this work is presented at https://lnkd.in/gBhJmSRa
Corrective info about the errata in the paper of the proceeding is provided.
final camera-ready paper
http://ieeexplore.ieee.org/document/8048295/
pre-print
https://www.researchgate.net/publication/319973013_Joint_compensation_of_CIM3_and_IQ_imbalance_in_the_up-conversion_mixer_with_a_single_skew_matrix
Explaining implementation and analysis of two well known DFA minimisation algorithms namely Morore and Hopcroft, in Map Reduce using Hadoop. Cost analysis and complexity are described.
Please follow this link: http://dl.acm.org/citation.cfm?id=2926537
OPTIMAL BEAM STEERING ANGLES OF A SENSOR ARRAY FOR A MULTIPLE SOURCE SCENARIOcsandit
We present the gradient and Hessian of the trace of the multivariate Cramér-Rao bound (CRB)
formula for unknown impinging angles of plane waves with non-unitary beamspace measurements,. These gradient and Hessian can be used to find the optimal beamspace
transformation matrix, i.e., the optimum beamsteering angles, using the Newton-Raphson iteration. These trace formulas are particularly useful to deal with the multiple source senario.
We also show the mean squred error (MSE) performance gain of the optimally steered beamspace measurements compared with the usuall DFT steered measurements, when the angle
of arrivals (AOAs) are estimated with stochastic maximum likelihood (SMLE) algorithm.
We introduce a sparse kernel learning framework for the Continuous Relevance Model (CRM). State-of-the-art image annotation models linearly combine evidence from several different feature types to improve image annotation accuracy. While previous authors have focused on learning the linear combination weights for these features, there has been no work examining the optimal combination of kernels. We address this gap by formulating a sparse kernel learning framework for the CRM, dubbed the SKL-CRM, that greedily selects an optimal combination of kernels. Our kernel learning framework rapidly converges to an annotation accuracy that substantially outperforms a host of state-of-the-art annotation models. We make two surprising conclusions: firstly, if the kernels are chosen correctly, only a very small number of features are required so to achieve superior performance over models that utilise a full suite of feature types; and secondly, the standard default selection of kernels commonly used in the literature is sub-optimal, and it is much better to adapt the kernel choice based on the feature type and image dataset.
Presentation at IEEE WCNC 2018 on simple asymptotic bounds on channel estimation and prediction. This work is the presentation of the following paper: https://sfx.aub.aau.dk/sfxaub?sid=pureportal&doi=10.1109/WCNC.2018.8377005.
Fixed Point Realization of Iterative LR-Aided Soft MIMO Decoding AlgorithmCSCJournals
Multiple-input multiple-output (MIMO) systems have been widely acclaimed in order to provide high data rates. Recently Lattice Reduction (LR) aided detectors have been proposed to achieve near Maximum Likelihood (ML) performance with low complexity. In this paper, we develop the fixed point design of an iterative soft decision based LR-aided K-best decoder, which reduces the complexity of existing sphere decoder. A simulation based word-length optimization is presented for physical implementation of the K-best decoder. Simulations show that the fixed point result of 16 bit precision can keep bit error rate (BER) degradation within 0.3 dB for 8×8 MIMO systems with different modulation schemes.
Iterative Soft Decision Based Complex K-best MIMO DecoderCSCJournals
This paper presents an iterative soft decision based complex multiple input multiple output (MIMO) decoding algorithm, which reduces the complexity of Maximum Likelihood (ML) detector. We develop a novel iterative complex K-best decoder exploiting the techniques of lattice reduction for 8×8 MIMO. Besides list size, a new adjustable variable has been introduced in order to control the on-demand child expansion. Following this method, we obtain 6.9 to 8.0 dB improvement over real domain K-best decoder and 1.4 to 2.5 dB better performance compared to iterative conventional complex decoder for 4th iteration and 64-QAM modulation scheme. We also demonstrate the significance of new parameter on bit error rate. The proposed decoder not only increases the performance, but also reduces the computational complexity to a certain level.
Iterative Soft Decision Based Complex K-best MIMO DecoderCSCJournals
This paper presents an iterative soft decision based complex multiple input multiple output (MIMO) decoding algorithm, which reduces the complexity of Maximum Likelihood (ML) detector. We develop a novel iterative complex K-best decoder exploiting the techniques of lattice reduction for 8×8 MIMO. Besides list size, a new adjustable variable has been introduced in order to control the on-demand child expansion. Following this method, we obtain 6.9 to 8.0 dB improvement over real domain K-best decoder and 1.4 to 2.5 dB better performance compared to iterative conventional complex decoder for 4th iteration and 64-QAM modulation scheme. We also demonstrate the significance of new parameter on bit error rate. The proposed decoder not only increases the performance, but also reduces the computational complexity to a certain level.
Performance Analysis of PAPR Reduction in MIMO-OFDMIJARBEST JOURNAL
Authors: Jayaraman.G1, VeeraKumar K2, Selvakani.S3
Abstract— In communication system, it is aimed to provide highest possible
transmission rate at the lowest possible power and with the least possible noise. MIMOOFDM
has been chosen for high data rate communications and widely deployed in many
wireless communication standards. The major drawback in OFDM signal transmission is
high PAPR. In previous, use clipping technique to tackle this problem. In this paper, use
EM-GAMP algorithm to reduce PAPR in considerable amount.
This presentation contains the concepts of frequency domain filtering of digital images. This includes the different kinds of filters used in frequency domain analysis,their characteristics and various phenomenon such as aliasing, inverse filtering etc. The contents are taken from variety of sources like Gonzalez image processing book, Pratt image processing book and some on-line resources.
DFA minimization algorithms in map reduceIraj Hedayati
Explaining implementation and analysis of two well known DFA minimisation algorithms namely Morore and Hopcroft, in Map Reduce using Hadoop. Cost analysis and complexity are described.
Please follow this link: http://spectrum.library.concordia.ca/980838/
Joint Compensation of CIM3 and I/Q Imbalance in the Up-conversion Mixer with ...Ealwan Lee
Slides used during the lecture in RFIT-2017 on Aug 31, 2017(Seoul, Korea)
Refined Model for this work is presented at https://lnkd.in/gBhJmSRa
Corrective info about the errata in the paper of the proceeding is provided.
final camera-ready paper
http://ieeexplore.ieee.org/document/8048295/
pre-print
https://www.researchgate.net/publication/319973013_Joint_compensation_of_CIM3_and_IQ_imbalance_in_the_up-conversion_mixer_with_a_single_skew_matrix
Explaining implementation and analysis of two well known DFA minimisation algorithms namely Morore and Hopcroft, in Map Reduce using Hadoop. Cost analysis and complexity are described.
Please follow this link: http://dl.acm.org/citation.cfm?id=2926537
OPTIMAL BEAM STEERING ANGLES OF A SENSOR ARRAY FOR A MULTIPLE SOURCE SCENARIOcsandit
We present the gradient and Hessian of the trace of the multivariate Cramér-Rao bound (CRB)
formula for unknown impinging angles of plane waves with non-unitary beamspace measurements,. These gradient and Hessian can be used to find the optimal beamspace
transformation matrix, i.e., the optimum beamsteering angles, using the Newton-Raphson iteration. These trace formulas are particularly useful to deal with the multiple source senario.
We also show the mean squred error (MSE) performance gain of the optimally steered beamspace measurements compared with the usuall DFT steered measurements, when the angle
of arrivals (AOAs) are estimated with stochastic maximum likelihood (SMLE) algorithm.
We introduce a sparse kernel learning framework for the Continuous Relevance Model (CRM). State-of-the-art image annotation models linearly combine evidence from several different feature types to improve image annotation accuracy. While previous authors have focused on learning the linear combination weights for these features, there has been no work examining the optimal combination of kernels. We address this gap by formulating a sparse kernel learning framework for the CRM, dubbed the SKL-CRM, that greedily selects an optimal combination of kernels. Our kernel learning framework rapidly converges to an annotation accuracy that substantially outperforms a host of state-of-the-art annotation models. We make two surprising conclusions: firstly, if the kernels are chosen correctly, only a very small number of features are required so to achieve superior performance over models that utilise a full suite of feature types; and secondly, the standard default selection of kernels commonly used in the literature is sub-optimal, and it is much better to adapt the kernel choice based on the feature type and image dataset.
Presentation at IEEE WCNC 2018 on simple asymptotic bounds on channel estimation and prediction. This work is the presentation of the following paper: https://sfx.aub.aau.dk/sfxaub?sid=pureportal&doi=10.1109/WCNC.2018.8377005.
Fixed Point Realization of Iterative LR-Aided Soft MIMO Decoding AlgorithmCSCJournals
Multiple-input multiple-output (MIMO) systems have been widely acclaimed in order to provide high data rates. Recently Lattice Reduction (LR) aided detectors have been proposed to achieve near Maximum Likelihood (ML) performance with low complexity. In this paper, we develop the fixed point design of an iterative soft decision based LR-aided K-best decoder, which reduces the complexity of existing sphere decoder. A simulation based word-length optimization is presented for physical implementation of the K-best decoder. Simulations show that the fixed point result of 16 bit precision can keep bit error rate (BER) degradation within 0.3 dB for 8×8 MIMO systems with different modulation schemes.
Iterative Soft Decision Based Complex K-best MIMO DecoderCSCJournals
This paper presents an iterative soft decision based complex multiple input multiple output (MIMO) decoding algorithm, which reduces the complexity of Maximum Likelihood (ML) detector. We develop a novel iterative complex K-best decoder exploiting the techniques of lattice reduction for 8×8 MIMO. Besides list size, a new adjustable variable has been introduced in order to control the on-demand child expansion. Following this method, we obtain 6.9 to 8.0 dB improvement over real domain K-best decoder and 1.4 to 2.5 dB better performance compared to iterative conventional complex decoder for 4th iteration and 64-QAM modulation scheme. We also demonstrate the significance of new parameter on bit error rate. The proposed decoder not only increases the performance, but also reduces the computational complexity to a certain level.
Iterative Soft Decision Based Complex K-best MIMO DecoderCSCJournals
This paper presents an iterative soft decision based complex multiple input multiple output (MIMO) decoding algorithm, which reduces the complexity of Maximum Likelihood (ML) detector. We develop a novel iterative complex K-best decoder exploiting the techniques of lattice reduction for 8×8 MIMO. Besides list size, a new adjustable variable has been introduced in order to control the on-demand child expansion. Following this method, we obtain 6.9 to 8.0 dB improvement over real domain K-best decoder and 1.4 to 2.5 dB better performance compared to iterative conventional complex decoder for 4th iteration and 64-QAM modulation scheme. We also demonstrate the significance of new parameter on bit error rate. The proposed decoder not only increases the performance, but also reduces the computational complexity to a certain level.
This presentation on Pseudo Random Number Generator enlists the different generators, their mechanisms and the various applications of random numbers and pseudo random numbers in different arenas.
OPTIMIZED RATE ALLOCATION OF HYPERSPECTRAL IMAGES IN COMPRESSED DOMAIN USING ...Pioneer Natural Resources
This paper studies the application of bit allocation using JPEG2000 for compressing multi-dimensional remote sensing data. Past experiments have shown that the Karhunen- Lo
`
e
ve transform (KLT) along with rate distortion optimal(RDO) bit allocation produces good compression perfor-mance. However, this model has the unavoidable disadvan-tage of paying a price in terms of implementation complex-ity. In this research we address this complexity problem byusing the discrete wavelet transform (DWT) instead of theKLT as the decorrelator. Further, we have incorporated amixed model (MM) to find the rate distortion curves instead of the prior method of using experimental rate distortioncurves for RDO bit allocation. We compared our results tothe traditional high bit rate quantizer bit allocation modelbased on the logarithm of variances among the bands. Our comparisons show that by using the MM-RDO bit rate al-location method result in lower mean squared error (MSE)compared to the traditional bit allocation scheme. Our ap- proach also has an additional advantage of using DWT asa computationally efficient decorrelator when compared tothe KLT
Analysis of Adaptive and Advanced Speckle Filters on SAR DataIOSRjournaljce
Synthetic Aperture RADAR(SAR) images get inherently affected by speckle noise which is multiplicative in nature. This noise affects the image spatial statistics and properties. Over the past several years, many SAR denoising algorithms have been developed to reduce speckle noise. Some of the standard speckle filters are Gamma MAP, Lee, Frost and Kuan filters. Further, these have also been modified to obtain better results after filtering, than their original counterparts. Apart from the standard speckle filters, advanced SAR filters like Block Matching 3 Dimensional (BM3D) are also present. In this paper several standard as well as advanced speckle filters have been analyzed and compared. For comparison, Quality Assessment has been performed where the filtered images are compared to each other using parameters like Radiometric Resolution and others. These parameters help to distinguish the performance of the filters on basis of signal strength, speckle reduction, mean preservation and edge and feature preservation. In the paper, radiometric resolution, speckle index and mean preservation index will be used to analyze among the performance of the filters.
International Journal of Engineering Research and Development (IJERD)IJERD Editor
journal publishing, how to publish research paper, Call For research paper, international journal, publishing a paper, IJERD, journal of science and technology, how to get a research paper published, publishing a paper, publishing of journal, publishing of research paper, reserach and review articles, IJERD Journal, How to publish your research paper, publish research paper, open access engineering journal, Engineering journal, Mathemetics journal, Physics journal, Chemistry journal, Computer Engineering, Computer Science journal, how to submit your paper, peer reviw journal, indexed journal, reserach and review articles, engineering journal, www.ijerd.com, research journals,
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論文紹介
S. Yang, H. Lu, S. Kang, L. Xie and D. Yu, "Enhancing Hybrid Self-attention Structure with Relative-position-aware Bias for Speech Synthesis," Proc. ICASSP, pp. 6910-6914, 2019.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
1. GMMN
A Study of Sparse Approximation of Gram Matrices
for GMMN-based Speech Synthesis
2. Background
‣ Statistical speech synthesis
•Model the relationship between input context and output acoustic
features
- In general, synthetic speech is always the same in perception
if the sentence is the same
- Different from real human communication
‣ Sampling-based speech synthesis [Takamichi et al., 2017]
•Models the relationship between input context and
the distribution of output acoustic features
•Samples speech parameter from the distribution
•Uses generative moment matching network (GMMN) as a model
3. Generative moment matching network (GMMN)
‣ Generative model based on DNN
•Predict the sample of output distribution from noise vector
•Use conditional maximum mean discrepancy (CMMD) as a cost
function
•Applications
- i-vector for speaker verification [Shiota et al., 2018]
- singing voice for double-tracking [Tamaru et al., 2019]
•Advantage
- Sampling is easily performed without considering parametric p.d.f.
- Min-max optimization is not required
4. Purpose
‣ Computational complexity problem
•CMMD is computationally infeasible for a large amount of data
- when N is the number of training data points
•Conventional method
- Partitions data based on randomly selected minibatch
- Calculates CMMD for each minibatch
‣ Purpose of this study
O(N3
)
•Review the approximation method of CMMD, which is used as a
cost function of GMNN
•Evaluate naturalness and diversity of generates synthetic speech
5. Maximum Mean Discrepancy [Gretton et al.,, 2012]
The distance of two distributions is defined by
the distance of means of RKHS points
{yi} {˜yi}
ϕ(y) ϕ(y)
RKHS RKHS
μ ˜μ
𝔼[ ⋅ ] 𝔼[ ⋅ ]
MMD2
= ∥μ − ˜μ∥2
P(Y) P( ˜Y)
6. Conditional MMD (CMMD) [Ren et al.,, 2012]
The distance of two conditional distributions is defined by
the distance of linear operator of RKHSs
{yi} {˜yi}
ϕ(y) ϕ(y)
RKHS RKHS
μ = Cψ(x) ˜μ = ˜Cψ(x)
𝔼[ ⋅ ] 𝔼[ ⋅ ]
CMMD2
= ∥C − ˜C∥2
x
ψ(x)
RKHS
P(Y|x)
P( ˜Y|x)
7. Conditional MMD (CMMD)
CMMD2
= ∥C − ˜C∥2
CMMD2
= Tr [(KY,Y + K˜Y, ˜Y − 2KY, ˜Y)(H + λI)−1
H(H + λI)−1
]
– Linear operators are estimated by kernel regressionC, ˜C
– Kernel trick is used
The distance of two conditional distributions is calculated by
the kernel functions of input features and output features
Gram matrices for output Gram matrix for input
8. Generative Moment Matching Network (GMMN)
[Ren et al.,, 2012]
Predict the samples of conditional distributions
using DNN, which is trained by CMMD cost function
{yi}
x {ni; ni ∼ 𝒩(0,I)}
DNN (GMNN)
{˜yi}
CMMD
: training data points
: noise
backprop
9. GMMN-Based Speech Synthesis
Use two DNNs, MSE criterion and
CMMD criterion that predicts residual of acoustic features
Gram
matrix
Gram
matrix
DNN with
MSE criterion
Context
Acoustic
feature
Bottleneck
feature
CMMD
Random vaue
GMMN for
sampling
10. Problem of GMMN-based speech synthesis
CMMD2
= Tr [(KY,Y + K˜Y, ˜Y − 2KY, ˜Y)(H + λI)−1
H(H + λI)−1
]
2. Calculation of inverse matrix
1. Calculation of Gram matrices
O(N2
)
O(N3
)
‣ Impossible to use CMMD directly for speech synthesis,
because N of speech synthesis is large
‣ Unable to train a model by Minibatch-based optimization
11. Local Approximation (Conventional Method)
‣ CMMD is calculated for each partitioned minibatch
‣ This method is regarded as block diagonal approximation
•Blocks are determined by minibatch
‣ Computational complexity for each minibatch:
•B: minibatch size
CMMD2
= Tr [(KY,Y + K˜Y, ˜Y − 2KY, ˜Y)(H + λI)−1
H(H + λI)−1
]
O(B3
)
12. Random Fourier Features (RFF) [Rahimi & Recht, 2008]
Kernel function is approximated by the inner product of a finite
number of basis to obtain low-rank Gram matrix
kRBF(x, x′) = (exp( −∥x − x′∥2
/2) kRBF(x, x′) ≈
1
M
M
∑
r=1
cos(x⊤
ωr + br)cos(x′⊤
ωr + br)
RBF kernel RBF kernel approx. with RFF
example:
-1.0
1.0
0.0
-1.0
1.0
0.0
Gram matrix with rank N=1000 Gram matrix with rank M=100
13. RFF-based Approximation
‣ Approximate Gram matrices of input features by RFF
‣ Can reduce computational complexity by matrix inversion
formula
‣ Computational complexity for each minibatch:
•B: minibatch size, M: RFF dimensions
CMMD2
= Tr [(KY,Y + K˜Y, ˜Y − 2KY, ˜Y)(H + λI)−1
H(H + λI)−1
]
O(BM2
)
low rank low rank
14. Clustering for Minibatch Selection
‣ Conventional method chose minibatch randomly
•Gram matrices tended to be sparse
- Since /a/ and /s/ are distant, kernel function value is almost zero
•Sparse matrix is redundant
‣ Collect similar contexts and use cluster as minibatch
•Perform K-means clustering (K=2) on bottleneck features
•Top-down partition until cluster size becomes sufficiently small
15. Experimental Conditions
Database
1 female, 203 sentences
(ATR B-set subset a & j
REPEAT included in JSUT corpus)
Each sentence was repeated 5 times.
Training data 5 x 150 utterances (ATR-a and REPEAT)
Development set 5 x 26 utterances (ATR-j27 to j53)
Test data 27 utterances (ATR-j01 to j26), 5 samples are generated
Acoustic
features
0-39th mel-cepstrum, log F0, and 5-band aperiodicity
with their delta and delta-delta, and VUV
19. Subjective Evaluation: Diversity
95% confidence interval
p<0.05 p<0.001
MSE
1 2 3 4 5
LOCAL-RAND
LOCAL-CLST
RFF-RAND
RFF-CLST
VOC
Score
(1: completely equivalent, 5: very different)
• Participants listened to two samples generated using different random inputs
• They rate how different two samples are in 5 point scale
20. Variance of Sampled Speech Parameters
The score of diversity increased with the variance of phone
duration
0-th mel-
cepstrum
1-st mel-
cepstrum
log F0
[cent]
phone
duration
[ms]
Diversity
MOS
LOCAL-RAND 0.023 0.012 15.8 2.46 1.61
LOCAL-CLST 0.053 0.022 18.2 3.50 1.71
RFF-RAND 0.021 0.007 1.5 3.77 1.73
RFF-CLST 0.049 0.027 14.0 5.47 1.94
21. Conclusions
‣ Examined the approximation methods to reduce
computational complexity of GMMN-based speech
synthesis
•Local approximation / Low rank approximation (RFF)
•Minibatch selection using clustering
‣ RFF and clustering-based minibatch improved diversity
‣ Future work
•Employ sequence-level modeling
•Use more data
•Investigate evaluation method of sampling-based TTS