What are glyconutrients? How do glyconutrients work? Where to get glyconutrients for $89 a pound? Find the answers here.
http://www.glycoinformation.com/
Bamboo Reinforced Concrete Truss Bridge for Rural InfrastructureIJERA Editor
Bamboo is one of a potential renewable construction material in the village. Bamboo is known to have a high mechanical strength in direction of the fibers. The weakness of bamboo in lateral direction of the fiber could be solved by constructing a composite structure with the concrete. The appropriate construction with hold the loads in axial direction is a truss structure. In a bamboo concrete truss structure, the bars are composed from the concrete column with a bamboo reinforcement. The research studies about the performance of the bridge and the effect of loading position on the strain and deformation of bamboo reinforced concrete truss bridge. The bridge whose span and width are respectively 1.5 m and 1.2 m was prepared. Load applied to the truss bridge conducted by using vehicle load changes with position. Mounting the strains gauge in bamboo reinforcement of primary truss is to observe the strain. The LVDT is used to observe the deflection of the truss bridge. The results show that the loading position influences the strain and deformation as well as a theoretical view.
Evaluating pollution potential of leachate from landfill site, from the Tangi...IJERA Editor
Leachate from municipalities’ landfills represents a potential health risk to ecosystems in generally and human populations in particularly. This study which was taken during year from 2010 to 2011was focused to study the physicochemical evaluation of the leachate from the landfill of the Tangier city (north of Morocco). The analyses of the sampled leachate revealed strong content of biodegradable organic matter (BOD =166.78 mg/l, COD=2397.25 mg/l and BOD/COD=0.069) and of SM (SM = 577.97 mg/l). Contents in nitrate (NO3=199.77 mg/l) were also revealed. The discharge of the Tangier city is characterized by an old leachate. The long-term monitoring of the evaluation of physicochemical parameters in polluted leachate, on how environmental conditions change over time, could then lead to models useful in the prediction of natural attenuation in aquifers. Therefore, an adaptable and efficient treatment process must be used to eliminate the wide range of pollutants present in leachate.
Waste Metal For Improving Concrete Performance And Utilisation As An Alternat...IJERA Editor
Waste material disposal is considered as a difficult issue to adopt in current world. Waste metal, which has been
recognised as a major problem in the environment and resource deficiency, could have important implications in
the concrete construction industries. Waste metal utilisation in construction of reinforced cement concrete (RCC)
works is immerging in recent time. Construction industries are looking for cost effective structural materials and
utilisation of renewable materials. Metal waste such as chips of tin, still and other metal fragments which is
abandoned and spread in the environment could be utilize as a replacement of traditional steel reinforcement bar
in the RCC. In this experiment, three different types of waste metal have been compared with commercial 40, 60
and 72 graded steel reinforcement bar. Compressive strength class of C25 concrete was used in the experiment
and mechanical properties of concrete incorporating different waste metal were investigated in the first stage.
Finally, three-point bend test on short beam was performed to compare their performances. Smaller metal
fragments has shown better performance through micro crack bridging in concrete during loading stage and
hence better than ordinary reinforcement concrete structure in some extent.
Buckling and Pull-In Instability of Multi-Walled Carbon Nanotube Probes Near ...IJERA Editor
In this paper, integration of the power series method and the Padé approximants (PS-Padé) is utilized to study buckling and pull-in instability of multi-walled carbon nanotube (MWCNT) cantilevers in the vicinity of graphite sheets due to intermolecular forces. A hybrid nano-scale continuum model based on the Lennard–Jones potential is used to simulate the Van der Waals forces and evaluate the buckling of MWCNT. A closed form power series, based on the symbolic power series polynomials, is utilized to obtain a series solution for the governing boundary value differential equation of the nanotube. In order to handle the boundary conditions and increasing the accuracy of solution, the symbolic power series are transformed into Padé approximants. The governing differential equation is also solved numerically using the finite difference method. The PS-Padé results are compared with the numerical results and other methods reported in literature. The results obtained by using the PS-Padé approach correspond very well with the numerical results. Furthermore, the detachment length and the minimum gap between MWCNT and the graphite plane as important parameters of engineering designs are computed. It is found that for a fixed gap, the detachment length of a MWCNT can be increased with the increase of the radius, wall thickness and the effective Young modulus of the MWCNT.
Laboratory Analysis of Fly Ash Mix Cement Concrete for Rigid Pavement.IJERA Editor
This study investigated the engineering properties of fly ash concrete for rigid pavement construction. Concrete cubes and beams were prepared with 0%, 10%, 20%, 30%, and 40% fly ash replacement of cement by weight. The specimens were tested for compressive strength, flexural strength, and workability at various ages. Results showed that compressive and flexural strength increased up to 30% fly ash replacement compared to the control mix. Workability decreased with higher fly ash content due to the spherical shape of fly ash particles. The study concluded that 30% fly ash concrete provides acceptable strength for rigid pavements while providing environmental and economic benefits over traditional concrete.
Design of a Low Power Combinational Circuit by using Adiabatic LogicIJERA Editor
A novel low power and Positive Feedback Adiabatic Logic (PFAL) combinational low power circuit is presented in this paper. The power consumption and general characteristics of the PFAL combinationallow power circuit arethen compared against two combinational low power circuit Efficient Charge Recovery Logic (ECRL), Conventional CMOS. The proposed PFAL combinational low power circuit design was proven to be superior to the other two designs in power dissipation and area. The combination of low power and low transistor count makes the new PFAL cell a viable option for low power design.
Concrete Poetry and It’s Varieties in Persian PoetryIJERA Editor
Concrete poetry is a form of visual poetry which is known as imaginary poetry, in Persian language. We can enter the genealogy of concrete poetry from two perspectives, First Persian acrostic Moshajjar and Mottayar poetry, the other one is French poet, Guillaume Apollinaire lyrics, which is known to Cali grams.But the systematic concrete poetry formed by poets such as Eugene Gvmanzhh, Gstvdh Pygmatary Campos and in South America.In contemporary Iranian poetry, visual aspect of poetry considered by poets and different varieties of this type has been created. Unlike traditional poetry, which is dependent on words, elements of fantasy, metaphors and symbols, Concrete poetry realization requires an understanding of the visual aspect of it, which is achieved through cooperation of concrete elements and techniques.This kind of poetry has a direct relationship with exploration, understanding and audience reception.In fact, it is the audience who makes and completes the work, by receiving the hidden layer of poetry. The poet does not end the poetry,because the audience completes the text by exploring the relationship between implicit and explicit and reading the unwritten parts. In this study, we follow the historical discussion of concrete poetry,and the way it shaped, and how the poets entered concrete poetry,and we try to present a new classification, according to the poems that have been classified as concrete.
This document discusses metrics for measuring reusability in source code. It proposes a method for identifying reusable modules in source code by calculating various metrics. The document first discusses previous work on measuring reusability based on size of reused code versus new code. It then discusses properties like complexity, size, dependencies that affect a module's reusability. Various metrics are proposed to measure attributes like understandability, maintainability, and adaptability that influence reusability. These include lines of code, comment percentage, weighted methods per class, depth of inheritance tree, number of children, and coupling. The goal is to help identify existing reusable components and improve software development productivity through reuse.
Bamboo Reinforced Concrete Truss Bridge for Rural InfrastructureIJERA Editor
Bamboo is one of a potential renewable construction material in the village. Bamboo is known to have a high mechanical strength in direction of the fibers. The weakness of bamboo in lateral direction of the fiber could be solved by constructing a composite structure with the concrete. The appropriate construction with hold the loads in axial direction is a truss structure. In a bamboo concrete truss structure, the bars are composed from the concrete column with a bamboo reinforcement. The research studies about the performance of the bridge and the effect of loading position on the strain and deformation of bamboo reinforced concrete truss bridge. The bridge whose span and width are respectively 1.5 m and 1.2 m was prepared. Load applied to the truss bridge conducted by using vehicle load changes with position. Mounting the strains gauge in bamboo reinforcement of primary truss is to observe the strain. The LVDT is used to observe the deflection of the truss bridge. The results show that the loading position influences the strain and deformation as well as a theoretical view.
Evaluating pollution potential of leachate from landfill site, from the Tangi...IJERA Editor
Leachate from municipalities’ landfills represents a potential health risk to ecosystems in generally and human populations in particularly. This study which was taken during year from 2010 to 2011was focused to study the physicochemical evaluation of the leachate from the landfill of the Tangier city (north of Morocco). The analyses of the sampled leachate revealed strong content of biodegradable organic matter (BOD =166.78 mg/l, COD=2397.25 mg/l and BOD/COD=0.069) and of SM (SM = 577.97 mg/l). Contents in nitrate (NO3=199.77 mg/l) were also revealed. The discharge of the Tangier city is characterized by an old leachate. The long-term monitoring of the evaluation of physicochemical parameters in polluted leachate, on how environmental conditions change over time, could then lead to models useful in the prediction of natural attenuation in aquifers. Therefore, an adaptable and efficient treatment process must be used to eliminate the wide range of pollutants present in leachate.
Waste Metal For Improving Concrete Performance And Utilisation As An Alternat...IJERA Editor
Waste material disposal is considered as a difficult issue to adopt in current world. Waste metal, which has been
recognised as a major problem in the environment and resource deficiency, could have important implications in
the concrete construction industries. Waste metal utilisation in construction of reinforced cement concrete (RCC)
works is immerging in recent time. Construction industries are looking for cost effective structural materials and
utilisation of renewable materials. Metal waste such as chips of tin, still and other metal fragments which is
abandoned and spread in the environment could be utilize as a replacement of traditional steel reinforcement bar
in the RCC. In this experiment, three different types of waste metal have been compared with commercial 40, 60
and 72 graded steel reinforcement bar. Compressive strength class of C25 concrete was used in the experiment
and mechanical properties of concrete incorporating different waste metal were investigated in the first stage.
Finally, three-point bend test on short beam was performed to compare their performances. Smaller metal
fragments has shown better performance through micro crack bridging in concrete during loading stage and
hence better than ordinary reinforcement concrete structure in some extent.
Buckling and Pull-In Instability of Multi-Walled Carbon Nanotube Probes Near ...IJERA Editor
In this paper, integration of the power series method and the Padé approximants (PS-Padé) is utilized to study buckling and pull-in instability of multi-walled carbon nanotube (MWCNT) cantilevers in the vicinity of graphite sheets due to intermolecular forces. A hybrid nano-scale continuum model based on the Lennard–Jones potential is used to simulate the Van der Waals forces and evaluate the buckling of MWCNT. A closed form power series, based on the symbolic power series polynomials, is utilized to obtain a series solution for the governing boundary value differential equation of the nanotube. In order to handle the boundary conditions and increasing the accuracy of solution, the symbolic power series are transformed into Padé approximants. The governing differential equation is also solved numerically using the finite difference method. The PS-Padé results are compared with the numerical results and other methods reported in literature. The results obtained by using the PS-Padé approach correspond very well with the numerical results. Furthermore, the detachment length and the minimum gap between MWCNT and the graphite plane as important parameters of engineering designs are computed. It is found that for a fixed gap, the detachment length of a MWCNT can be increased with the increase of the radius, wall thickness and the effective Young modulus of the MWCNT.
Laboratory Analysis of Fly Ash Mix Cement Concrete for Rigid Pavement.IJERA Editor
This study investigated the engineering properties of fly ash concrete for rigid pavement construction. Concrete cubes and beams were prepared with 0%, 10%, 20%, 30%, and 40% fly ash replacement of cement by weight. The specimens were tested for compressive strength, flexural strength, and workability at various ages. Results showed that compressive and flexural strength increased up to 30% fly ash replacement compared to the control mix. Workability decreased with higher fly ash content due to the spherical shape of fly ash particles. The study concluded that 30% fly ash concrete provides acceptable strength for rigid pavements while providing environmental and economic benefits over traditional concrete.
Design of a Low Power Combinational Circuit by using Adiabatic LogicIJERA Editor
A novel low power and Positive Feedback Adiabatic Logic (PFAL) combinational low power circuit is presented in this paper. The power consumption and general characteristics of the PFAL combinationallow power circuit arethen compared against two combinational low power circuit Efficient Charge Recovery Logic (ECRL), Conventional CMOS. The proposed PFAL combinational low power circuit design was proven to be superior to the other two designs in power dissipation and area. The combination of low power and low transistor count makes the new PFAL cell a viable option for low power design.
Concrete Poetry and It’s Varieties in Persian PoetryIJERA Editor
Concrete poetry is a form of visual poetry which is known as imaginary poetry, in Persian language. We can enter the genealogy of concrete poetry from two perspectives, First Persian acrostic Moshajjar and Mottayar poetry, the other one is French poet, Guillaume Apollinaire lyrics, which is known to Cali grams.But the systematic concrete poetry formed by poets such as Eugene Gvmanzhh, Gstvdh Pygmatary Campos and in South America.In contemporary Iranian poetry, visual aspect of poetry considered by poets and different varieties of this type has been created. Unlike traditional poetry, which is dependent on words, elements of fantasy, metaphors and symbols, Concrete poetry realization requires an understanding of the visual aspect of it, which is achieved through cooperation of concrete elements and techniques.This kind of poetry has a direct relationship with exploration, understanding and audience reception.In fact, it is the audience who makes and completes the work, by receiving the hidden layer of poetry. The poet does not end the poetry,because the audience completes the text by exploring the relationship between implicit and explicit and reading the unwritten parts. In this study, we follow the historical discussion of concrete poetry,and the way it shaped, and how the poets entered concrete poetry,and we try to present a new classification, according to the poems that have been classified as concrete.
This document discusses metrics for measuring reusability in source code. It proposes a method for identifying reusable modules in source code by calculating various metrics. The document first discusses previous work on measuring reusability based on size of reused code versus new code. It then discusses properties like complexity, size, dependencies that affect a module's reusability. Various metrics are proposed to measure attributes like understandability, maintainability, and adaptability that influence reusability. These include lines of code, comment percentage, weighted methods per class, depth of inheritance tree, number of children, and coupling. The goal is to help identify existing reusable components and improve software development productivity through reuse.
The Comparative Study of Gray Model and Markov Model in Pavement Performance ...IJERA Editor
Pavement performance prediction is an essential component of pavement maintenance management system, which directly affects the choice of maintenance measures and funds. Firstly, this paper uses the Gray theoretical model to predict the status of certain highway pavement damaged. Secondly, the Grey theory and Markov prediction method are combined to forecast it. Finally, the comparison of the results between Grey theory and Markov prediction method analyzes the similarities and differences .The results show that Grey theoretical model is more suitable for recent forecasting, while combination method is suitable for longer-term forecasting.
Distributed Mathematical Model of Vasopressin in Patients with Severe Brain I...IJERA Editor
Disorders of water and sodium balance are frequently seen in patients with severe brain injury (SBI), and may worsen their prognosis. AVP serum levels remained within the normal range in SBI patients (either traumatic or non-traumatic), although tended to be greater in non-survivor than in survivor patients. AVP serum levels remained within the normal range values in these SBI patients, but those who died have shown higher incidence of abnormal sodium and water balance during the first week post-injury. We applied this to the steady-state availability of systems with times to outages and recoveries that are generally distributed. Also we provide the steady-state availability for a system subject to unplanned outages, for which times-to-outages are exponentially distributed and planned outages for which times-to outages have bounded distributions to check the damage of the hormonal levels.
El documento habla sobre la concepción holística del aprendizaje como un proceso que involucra todas las dimensiones del desarrollo humano. Reconoce que existen múltiples formas de aprender y diferentes estilos de aprendizaje. También menciona varios modelos de estilos de aprendizaje como VAK, Kolb y Honey-Munford. Finalmente, describe los elementos y procesos del aprendizaje como la sensibilización, atención, adquisición, personalización, recuperación y evaluación.
Ação direta de inconstitucionalidade 4Franck Lenzi
Este documento trata de uma Ação Direta de Inconstitucionalidade sobre a aplicação do regime jurídico da união estável às uniões entre pessoas do mesmo sexo. O relator Ministro Ayres Britto argumenta que o reconhecimento dessas uniões é obrigação constitucional devido aos princípios da dignidade humana e da liberdade, independentemente da omissão do legislador. Ele também discute a relação entre Direito e moralidade nesta questão.
La Unión Europea ha acordado un embargo petrolero contra Rusia en respuesta a la invasión de Ucrania. El embargo prohibirá las importaciones marítimas de petróleo ruso a la UE y pondrá fin a las entregas a través de oleoductos dentro de seis meses. Esta medida forma parte de un sexto paquete de sanciones de la UE destinadas a aumentar la presión económica sobre Moscú y privar al Kremlin de fondos para financiar su guerra.
El documento describe el origen e historia temprana de Internet. Comenzó como la red ARPANET desarrollada por DARPA en la década de 1960 para permitir que los ordenadores se comunicaran entre sí. La idea de una arquitectura de red abierta que permitiera la interconexión de múltiples redes independientes fue fundamental. Esto llevó al desarrollo de protocolos como TCP/IP que permitieron que diferentes redes se comunicaran entre sí y dieron origen a lo que hoy conocemos como Internet.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The document discusses best practices for social tools, knowledge management, and innovation. It provides links to resources on topics like serendipity, knowledge management, change agents, and using social tools to foster collaboration and knowledge sharing. The focus is on creating an environment where knowledge can flow freely and innovation can happen.
El documento es un aviso de convocatoria para una licitación pública del Municipio de Necoclí, Antioquia, para mejorar 41 km de vías terciarias en varias localidades. La licitación tiene un valor aproximado de $4.672.897.197 y un plazo de tres meses. Los interesados pueden presentar sus propuestas del 13 al 21 de agosto en las oficinas de la Alcaldía Municipal. Para participar, las propuestas deben cumplir con requisitos de experiencia, capacidad jurídica, financiera y organizacional
Este documento describe diferentes métodos para determinar los parámetros de una máquina síncrona, incluida la prueba de la tasa de caída de la componente DC. Esta prueba se realiza fuera de línea y permite determinar las reactancias de eje directo e indirecto, reactancias transitorias y subtransitorias, y constantes de tiempo mediante la medición de la caída de la corriente cuando se abre un interruptor mientras la máquina está alimentada por una fuente de corriente continua reducida.
A empresa anunciou um novo produto para competir no mercado de smartphones. O novo aparelho tem câmera de alta resolução, processador rápido e bateria de longa duração por preço acessível. A expectativa é que o lançamento ajude a empresa a aumentar sua participação no mercado.
Mercurius is named after the roman god mercurius, the god of trade and science. The planet mercurius is named after the same god. Mercurius is sometimes called hydrargyrum, means ‘watery silver’. Its shine and colour are very similar to silver, but mercury is a fluid at room temperatures. The name quick silver is a translation of hydrargyrum, where the word quick describes its tendency to scatter away in all directions.
The droplets have a tendency to conglomerate to one big mass, but on being shaken they fall apart into countless little droplets again. It is used to ignite explosives, like mercury fulminate, the explosive character is one of its general themes.
The Comparative Study of Gray Model and Markov Model in Pavement Performance ...IJERA Editor
Pavement performance prediction is an essential component of pavement maintenance management system, which directly affects the choice of maintenance measures and funds. Firstly, this paper uses the Gray theoretical model to predict the status of certain highway pavement damaged. Secondly, the Grey theory and Markov prediction method are combined to forecast it. Finally, the comparison of the results between Grey theory and Markov prediction method analyzes the similarities and differences .The results show that Grey theoretical model is more suitable for recent forecasting, while combination method is suitable for longer-term forecasting.
Distributed Mathematical Model of Vasopressin in Patients with Severe Brain I...IJERA Editor
Disorders of water and sodium balance are frequently seen in patients with severe brain injury (SBI), and may worsen their prognosis. AVP serum levels remained within the normal range in SBI patients (either traumatic or non-traumatic), although tended to be greater in non-survivor than in survivor patients. AVP serum levels remained within the normal range values in these SBI patients, but those who died have shown higher incidence of abnormal sodium and water balance during the first week post-injury. We applied this to the steady-state availability of systems with times to outages and recoveries that are generally distributed. Also we provide the steady-state availability for a system subject to unplanned outages, for which times-to-outages are exponentially distributed and planned outages for which times-to outages have bounded distributions to check the damage of the hormonal levels.
El documento habla sobre la concepción holística del aprendizaje como un proceso que involucra todas las dimensiones del desarrollo humano. Reconoce que existen múltiples formas de aprender y diferentes estilos de aprendizaje. También menciona varios modelos de estilos de aprendizaje como VAK, Kolb y Honey-Munford. Finalmente, describe los elementos y procesos del aprendizaje como la sensibilización, atención, adquisición, personalización, recuperación y evaluación.
Ação direta de inconstitucionalidade 4Franck Lenzi
Este documento trata de uma Ação Direta de Inconstitucionalidade sobre a aplicação do regime jurídico da união estável às uniões entre pessoas do mesmo sexo. O relator Ministro Ayres Britto argumenta que o reconhecimento dessas uniões é obrigação constitucional devido aos princípios da dignidade humana e da liberdade, independentemente da omissão do legislador. Ele também discute a relação entre Direito e moralidade nesta questão.
La Unión Europea ha acordado un embargo petrolero contra Rusia en respuesta a la invasión de Ucrania. El embargo prohibirá las importaciones marítimas de petróleo ruso a la UE y pondrá fin a las entregas a través de oleoductos dentro de seis meses. Esta medida forma parte de un sexto paquete de sanciones de la UE destinadas a aumentar la presión económica sobre Moscú y privar al Kremlin de fondos para financiar su guerra.
El documento describe el origen e historia temprana de Internet. Comenzó como la red ARPANET desarrollada por DARPA en la década de 1960 para permitir que los ordenadores se comunicaran entre sí. La idea de una arquitectura de red abierta que permitiera la interconexión de múltiples redes independientes fue fundamental. Esto llevó al desarrollo de protocolos como TCP/IP que permitieron que diferentes redes se comunicaran entre sí y dieron origen a lo que hoy conocemos como Internet.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
The document discusses best practices for social tools, knowledge management, and innovation. It provides links to resources on topics like serendipity, knowledge management, change agents, and using social tools to foster collaboration and knowledge sharing. The focus is on creating an environment where knowledge can flow freely and innovation can happen.
El documento es un aviso de convocatoria para una licitación pública del Municipio de Necoclí, Antioquia, para mejorar 41 km de vías terciarias en varias localidades. La licitación tiene un valor aproximado de $4.672.897.197 y un plazo de tres meses. Los interesados pueden presentar sus propuestas del 13 al 21 de agosto en las oficinas de la Alcaldía Municipal. Para participar, las propuestas deben cumplir con requisitos de experiencia, capacidad jurídica, financiera y organizacional
Este documento describe diferentes métodos para determinar los parámetros de una máquina síncrona, incluida la prueba de la tasa de caída de la componente DC. Esta prueba se realiza fuera de línea y permite determinar las reactancias de eje directo e indirecto, reactancias transitorias y subtransitorias, y constantes de tiempo mediante la medición de la caída de la corriente cuando se abre un interruptor mientras la máquina está alimentada por una fuente de corriente continua reducida.
A empresa anunciou um novo produto para competir no mercado de smartphones. O novo aparelho tem câmera de alta resolução, processador rápido e bateria de longa duração por preço acessível. A expectativa é que o lançamento ajude a empresa a aumentar sua participação no mercado.
Mercurius is named after the roman god mercurius, the god of trade and science. The planet mercurius is named after the same god. Mercurius is sometimes called hydrargyrum, means ‘watery silver’. Its shine and colour are very similar to silver, but mercury is a fluid at room temperatures. The name quick silver is a translation of hydrargyrum, where the word quick describes its tendency to scatter away in all directions.
The droplets have a tendency to conglomerate to one big mass, but on being shaken they fall apart into countless little droplets again. It is used to ignite explosives, like mercury fulminate, the explosive character is one of its general themes.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
2. Take Precaution While Purchasing Glyconutrients
Glyconutrients are an advanced and latest form of nutraceuticals. Generally people use the
terms nutraceuticals to denote medically healing products and medicines that are made out of
natural substances. These are also referred to as diet supplements that tend to improve and
optimize human health without causing any harmful side effects. Glyconutrient is a specialized
type of nutrition supplement that plays a vital role in enhancing and improving the ability of our
tissue cells to recognize and communicate with other tissue cells and therefore perform
better.They are responsible for providing monosaccharaides that are required for improvement
of human body health. The basic and fundamental body structure is what these special
nutrients deal with in order to optimize the functioning of the body and its various parts.
Collateral to this, the toxins that are harmful for the body are drained out or eliminated as well.
Quality Glyconutrients:
As we all know, every product is available in various quality standards. We can even come across
fake ones. Therefore it is highly important that we are fully aware of what we are going to
purchase and we must remain cautious and make sure that the product we are buying is original
and of standardized quality. Obviously you can't simply tell the quality of any medical or
nutritional product by just looking at its packing.
http://www.glycoinformation.com/