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Genomes are The Long Now (draft 1)
This document discusses how genomes provide information to answer old questions and ask new ones. It describes how ancient DNA samples carry important data and how the quest to rewrite the tree of life is never-ending. It also outlines how genomic data is organized today with reference genomes, annotation tracks, and links to additional data resources. Future directions discussed include pan-genome displays and concerns around personal genomics and de-extinction science.
Genomes are The Long Now (draft 1)
- 1. GENOMES ARE THE LONGNOW Mary Mangan, PhD OpenHelix February 6, 2017 @mem_somerville on twitter
- 2. ANSWERING AGE-OLD QUESTIONS ALLOWINGUS TO ASK NEW ONES
- 3. ANCIENT SAMPLES CARRYIMPORTANT INFORMATION
- 4. THE NEVER-ENDING QUESTTO REWRITE THE TREE OF LIFE www.rna-seqblog.com/ the-never-ending-quest-to-rewrite-the-tree-of-life www.pbs.org/wgbh/nova/next/evolution/microbial-diversity
- 5. HOW WE ORGANIZEGENOME DATA TODAY
- 6. Copyright OpenHelix. Nouse or reproduction without express written consent 6 ORGANIZATION OF GENOMIC DATA CONCEPTUAL LAYOUT OF A GENOME BROWSER PAGE Reference genome: base position numbersequence AnnotationTracks chromosome band predicted genes phenotype and disease evolutionary conservation SNPs and structural variation gap locations known genes repeated regions microarray/expression data more… enhancer/promoter data Links out to more data
- 7. GENOME.UCSC.EDU LIVE DEMO ATTEMPTEDHERE (DEPENDS ON INTERNET CONNECTION)
- 8. GENOME.UCSC.EDU DISCLOSURE: MY COMPANYHAS AN OUTREACH CONTRACT WITH UCSC GENOME BROWSER TP53
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