This document summarizes the African Development Bank's experience with an entrepreneurship ecosystem approach in Tunisia called Souk Attanmia. The program provided seed grants, mentoring, and co-financing to support entrepreneurs, especially those from disadvantaged regions, youth, and women. Over 2000 applications were received for the first round of funding and 61 projects were selected. The program leveraged 1 million euros to raise over twice that amount in financing from local banks. It is estimated the funded businesses will create 1000 new jobs. The African Development Bank plans to expand this approach to other countries and partner with more private sector and foundation partners.