This document discusses the importance of evidence-based practice in nursing. It notes that practices like bloodletting and certain wound treatments are no longer used because evidence does not support their effectiveness. Randomized controlled trials are considered the gold standard for evidence, but such trials are lacking for most medical practices. The document recommends determining if existing data from other study designs can provide useful evidence to guide practices, and clarifying the desired health outcomes, rather than relying solely on past practices not supported by evidence. It provides resources for finding synthesized evidence and promoting integrity in health research publication.