8. •They live in water
•Vibrio cholera is killed by:
Heating for 30 min at 56*C
By drying in sunlight
Bleaching powder
•El tor is more resistant than classical
•They produce a toxin called
ENTEROTOXIN
9. AGENT
HOST
MODE OF TRANSMISSION
PATHOGENESIS
CLINICAL FEATURES
CARRIER
LABORATORY DIAGNOSIS
CONTROL OF CHOLERA
15. AGENT
HOST
MODE OF TRANSMISSION
PATHOGENESIS
CLINICAL FEATURES
CARRIER
LABORATORY DIAGNOSIS
CONTROL OF CHOLERA
16. Entry is through oral route
Get adhered to small intestine
Incubation period is 2- days
Causes many symptoms
Get excreted to faeces and
vomiting
17.
18. • AGENT
• HOST
• MODE OF TRANSMISSION
• PATHOGENESIS
• CLINICAL FEATURES
• CARRIER
• LABORATORY DIAGNOSIS
CONTROL OF CHOLERA
19. Suspected
In an area where the disease is not known to
be present: severe dehydration or death from
acute watery diarrhoea in a patient aged 5
years or more;
In an area where there is cholera endemic:
acute watery diarrhoea, with or without
vomiting in a patient aged 5 years or more
Epidemic ongoing: acute watery diarrhoea
with or without vomitting
Confirmed
A suspected case that is laboratory-
confirmed.( Isolation of Vibrio cholerae O1 or
O139 from stools in any patient with diarrhoea
is the laboratory criteria for diagnosis)
20. • Stage of evacuation
• Stage of collapse
• Stage of recovery
21.
22.
23. • Sunken eyes
• Hollow cheeks
• Scaphoid abdomen
• Washerman hand and
feet
• Loss of elasticity of skin
• Sub-normal temperature
• Absent pulse
• Low BP
• Shallow and quick respiration
• Oliguria
24.
25.
26. AGENT
HOST
MODE OF TRANSMISSION
PATHOGENESIS
CLINICAL FEATURES
CARRIER
LABORATORY DIAGNOSIS
CONTROL OF CHOLERA
31. oLoss of at least 10% of body weight
oHypovolemic shock
oLow blood pressure
oRapid, weak, or undetectable
peripheral pulse
oSkin has lost normal turgor
(“tenting”)
oMouth is very dry
oThinking is dulled