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EPIDEMIOLOGY and
DISEASE TRANSMISSION
Factors that Contribute to the Spread of Disease
Virulence of
pathogen
Susceptibility of
the population
Lack of
immunization
Mode of
transmission of
the pathogen
Inadequate
sanitation
procedures
Reservoirs of Infections
• any site where the pathogen can multiply or merely survive
until it is transferred to the host
– Human reservoir
– Animal reservoir
– Inanimate reservoir
• principal living reservoir of disease because
many human pathogens are specie-specific
• carrier – harbors the pathogen but have no
signs and symptoms
Human Reservoir
Carrier
• incubatory carrier – transmits the pathogen during
the incubation period
• convalescent carrier – transmit pathogen during
convalescence or recovery period
• active carriers – completely recovered from
disease but continue to harbor the pathogen
indefinitely
• passive carriers – carry the pathogen without ever
having the disease
zoonoses- infectious diseases that humans
acquire from animal sources
Routes:
• Direct contact – with infected animal or
with domestic pet waste
• Inhalation – from contaminated hides,
fur, feathers
• Ingestion – contaminated food and
water; consumption of infected animal
products
• Injection of the pathogen – insect vector
Animal reservoir
Inanimate (non-living) reservoir
• e.g. air, soil, food, milk, water, and fomites
• Fomites – contaminated materials
• e.g. clothing, bedding, urinals/bedpans, eating and drinking
utensils
• Air – contaminated by dust, smoke, and respiratory
secretions of humans expelled into the air by
breathing, blowing, sneezing, and coughing
• Contact transmission
• Vehicle transmission
• Vector transmission
MODE OF TRANSMISSION
Contact Transmission
- spread of an agent of disease by direct, indirect or
droplet transmission
• Direct Contact Transmission
• person to person transmission of an agent by
• physical contact (source to susceptible host)
• no intermediate host involved i.e. touching,
• kissing, sexual intercourse
Contact Transmission…
• Indirect Contact Transmission
• from source to a non-living object to a
susceptible host
• Droplet Transmission
• Microbe spread in droplet nuclei that travels only
a short distance (<1 meter) i.e. coughing,
sneezing.
• Laughing or talking
transmission of disease agent by a medium
(i.e. water,
food, air, etc)
• Waterborne Transmission
• water contamination i.e. cholera,
Shigella
• Foodborne Transmission
• raw of poorly preserved or prepared
food
• Airborne Transmission
• spread of agents of infection by
droplet nuclei in dust that travel > 1
meter from the reservoir to host
Vehicle Transmission
Vector Transmission
animals that carry
pathogens from one
host to another
Control of Epidemic Disease
• Report cases of communicable diseases to proper
agencies
• Public education
• Identification and elimination of reservoirs of
infection
• Isolated disease person
• Participate in immunization program
• Help to treat sick person

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epidemiology and disease transmission2.pdf

  • 2. Factors that Contribute to the Spread of Disease Virulence of pathogen Susceptibility of the population Lack of immunization Mode of transmission of the pathogen Inadequate sanitation procedures
  • 3. Reservoirs of Infections • any site where the pathogen can multiply or merely survive until it is transferred to the host – Human reservoir – Animal reservoir – Inanimate reservoir
  • 4. • principal living reservoir of disease because many human pathogens are specie-specific • carrier – harbors the pathogen but have no signs and symptoms Human Reservoir
  • 5. Carrier • incubatory carrier – transmits the pathogen during the incubation period • convalescent carrier – transmit pathogen during convalescence or recovery period • active carriers – completely recovered from disease but continue to harbor the pathogen indefinitely • passive carriers – carry the pathogen without ever having the disease
  • 6. zoonoses- infectious diseases that humans acquire from animal sources Routes: • Direct contact – with infected animal or with domestic pet waste • Inhalation – from contaminated hides, fur, feathers • Ingestion – contaminated food and water; consumption of infected animal products • Injection of the pathogen – insect vector Animal reservoir
  • 7. Inanimate (non-living) reservoir • e.g. air, soil, food, milk, water, and fomites • Fomites – contaminated materials • e.g. clothing, bedding, urinals/bedpans, eating and drinking utensils • Air – contaminated by dust, smoke, and respiratory secretions of humans expelled into the air by breathing, blowing, sneezing, and coughing
  • 8. • Contact transmission • Vehicle transmission • Vector transmission MODE OF TRANSMISSION
  • 9. Contact Transmission - spread of an agent of disease by direct, indirect or droplet transmission • Direct Contact Transmission • person to person transmission of an agent by • physical contact (source to susceptible host) • no intermediate host involved i.e. touching, • kissing, sexual intercourse
  • 10. Contact Transmission… • Indirect Contact Transmission • from source to a non-living object to a susceptible host • Droplet Transmission • Microbe spread in droplet nuclei that travels only a short distance (<1 meter) i.e. coughing, sneezing. • Laughing or talking
  • 11. transmission of disease agent by a medium (i.e. water, food, air, etc) • Waterborne Transmission • water contamination i.e. cholera, Shigella • Foodborne Transmission • raw of poorly preserved or prepared food • Airborne Transmission • spread of agents of infection by droplet nuclei in dust that travel > 1 meter from the reservoir to host Vehicle Transmission
  • 12. Vector Transmission animals that carry pathogens from one host to another
  • 13. Control of Epidemic Disease • Report cases of communicable diseases to proper agencies • Public education • Identification and elimination of reservoirs of infection • Isolated disease person • Participate in immunization program • Help to treat sick person