This document provides a four-step model for strengthening and revitalizing state or tribal epidemiological workgroups: 1) take stock of available resources and goals for the group; 2) identify and interview potential members to determine if they have needed skills; 3) gauge existing members' interests to maintain engagement; 4) provide meaningful responsibilities and opportunities to sustain membership over time like involving members in decision making and product development. The goal is to create active, well-functioning groups that can engage in data-guided prevention planning.