Allegra is an antihistamine that reduces histamine in the body to relieve symptoms of sneezing, itching, watery eyes, and runny nose caused by allergies. Robitussin contains guaifenesin, an expectorant that helps loosen congestion in the chest and throat to make coughing easier. Flonase is a nasal spray containing the corticosteroid fluticasone that prevents inflammation and treats nasal symptoms like congestion from allergies.