early and late clinical manifestations of all oxygenation alterations. Solution Early clinical manifestations of all oxygenation alterations: 1. Restlessness or anxiety 2. Flaring of nostrils or pursed lips 3. Tachypnea 4. Dyspnea Late clinical manifestations of all oxygenation alterations: 1. Change in mental status 2. Changes in skin colour to bluish or gray 3. Cyanosis 4. Level of consciousness will decrease. 5. Hypotension 6. COPD 7. Heart failure 8. Anemia 9. Pneumonia.