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Jittipan Chavadej, Ph.D.
Anatomy Dept., Fac. of Science
Mahidol University
yr.,2000
Mature components of the ears
The ear is composed of inner,
middle and outer ear portions
• outer ear -auricle
-ext. auditory meatus
-tympanic membrane
• middle ear - malleus, incus & stapes
- auditory tube
• inner ear - cochlear duct
- semicircular canal
Formation of the ear
Dual origin
- thickened ectodermal
placode at rhombencephalon
- first and second branchial
arches
Rhombencephalon
region:formation
of otic vesicles
Derivatives of
the 1st & 2nd
branchial arches
Development of inner ear
Induction - rhombencephalon~surface
ectoderm
Otic placode Otic vesicle
Dorsal vestibular
region
Ventral cochlear
region
Rhombencephalon
region:otic placode ,
otic pit and otic
vesicle
Ventral cochlear region
Saccule Cochlear duct
Utricle Semicircular
canals
Endolymphatic
duct
Membranous labyrinth
Development of the otic vesicle showing a dorsal utricular
portion with endolymphatic duct, and a ventral saccular
portion
Saccule, cochlea & organ of Corti
Outgrowth of cochlear duct-spiral
fashion 8th wk.- 21/2 turns
Cochlear duct conect with saccule
through ductus reuniens
Cochlear duct + mesenchyme
Scala media
Cartilageous shell
Scala vestibuli Scala tympani
Vestibular mem.
Basilar mem.
Organ of Corti
(S.media & S.vestibuli)
Development of the scala tympani & scala vestibuli
Note:the auditory nerve and spiral ganglion
Scala media - organ of Corti
Hair cells Tectorial mem.
(gelatineous substance)
Lateral wall-spiral ligament
Medial - modiolus
- spiral ganglion
Development of the organ of Corti
Semicircular canals & Utricle
Vestibular portion-central portion
appose to each other disappearance
3 semicircular canals
Crus ampullare-crista ampullaris
Utricle&Saccule-maculae acousticae
Statoacoustic ganglion CN VIII
Development of the semicircular canals
Note:disappearance of the central portion & the ampullae
in the semicircular canals
Development of the Middle Ear
Expansion of 1st pharyngeal pouch
middle cavity & auditory tube
**Lining- endodermal origin**
2nd mo.-blind end oftubotympanic
tube 1st pharyngeal cleft
Development of the middle ear
Note:tubotympanic recess, mesenchymal condensation ear
ossicle formation
6thwk.-condensation of mesenchyme
(mesoderm):just dorsal to the end of tubotympanic
end ear ossicles
Tympanic cavity-ear ossicles in
loose mesenchyme late pregnancy:
programmed cell death suspension
of ear ossicles
2 mo. after birth-free movement
of ear ossicles
Development of the ear ossicles in the tympanic cavity
Note: malleus contact with eardrum, stapes contact with
oval window and endodermal epithelium of tympanic cavity
Dual origin of ear ossicles
•malleus & incus-mesoderm of 1st
branchial arch
•stapes-mesoderm of 2nd branchial
arch
*Tensor tympani mus.- CN V
*Stapedius - CN VII
Development of the External Ear
Pinna - mesenchyme of 1st &2nd
branchial arches:2nd mo. auricular
hillock enlargement(asymmetry)
External auditory meatus - inward
expansion of the 1st branchial cleft
3rd-meatal plug(solid epith. plate)
7th-dissolution of meatal plug
Lateral view of the head showing the six auricular hillocks
surrounding the dorsal end of the 1st pharyngeal cleft
Congenital malformation of the ear
•Congenital deafness-inner ear
deafness(rubella),middle ear
deafness (1st & 2nd arches),agenesis
of external ear
•Auricular anomalies
Ear development

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Ear development

  • 1. Jittipan Chavadej, Ph.D. Anatomy Dept., Fac. of Science Mahidol University yr.,2000
  • 2. Mature components of the ears The ear is composed of inner, middle and outer ear portions • outer ear -auricle -ext. auditory meatus -tympanic membrane • middle ear - malleus, incus & stapes - auditory tube • inner ear - cochlear duct - semicircular canal
  • 3. Formation of the ear Dual origin - thickened ectodermal placode at rhombencephalon - first and second branchial arches
  • 5. Development of inner ear Induction - rhombencephalon~surface ectoderm Otic placode Otic vesicle Dorsal vestibular region Ventral cochlear region
  • 7. Ventral cochlear region Saccule Cochlear duct Utricle Semicircular canals Endolymphatic duct Membranous labyrinth
  • 8. Development of the otic vesicle showing a dorsal utricular portion with endolymphatic duct, and a ventral saccular portion
  • 9. Saccule, cochlea & organ of Corti Outgrowth of cochlear duct-spiral fashion 8th wk.- 21/2 turns Cochlear duct conect with saccule through ductus reuniens
  • 10. Cochlear duct + mesenchyme Scala media Cartilageous shell Scala vestibuli Scala tympani Vestibular mem. Basilar mem. Organ of Corti (S.media & S.vestibuli)
  • 11. Development of the scala tympani & scala vestibuli Note:the auditory nerve and spiral ganglion
  • 12. Scala media - organ of Corti Hair cells Tectorial mem. (gelatineous substance) Lateral wall-spiral ligament Medial - modiolus - spiral ganglion
  • 13. Development of the organ of Corti
  • 14. Semicircular canals & Utricle Vestibular portion-central portion appose to each other disappearance 3 semicircular canals Crus ampullare-crista ampullaris Utricle&Saccule-maculae acousticae Statoacoustic ganglion CN VIII
  • 15. Development of the semicircular canals Note:disappearance of the central portion & the ampullae in the semicircular canals
  • 16. Development of the Middle Ear Expansion of 1st pharyngeal pouch middle cavity & auditory tube **Lining- endodermal origin** 2nd mo.-blind end oftubotympanic tube 1st pharyngeal cleft
  • 17. Development of the middle ear Note:tubotympanic recess, mesenchymal condensation ear ossicle formation
  • 18. 6thwk.-condensation of mesenchyme (mesoderm):just dorsal to the end of tubotympanic end ear ossicles Tympanic cavity-ear ossicles in loose mesenchyme late pregnancy: programmed cell death suspension of ear ossicles 2 mo. after birth-free movement of ear ossicles
  • 19. Development of the ear ossicles in the tympanic cavity Note: malleus contact with eardrum, stapes contact with oval window and endodermal epithelium of tympanic cavity
  • 20. Dual origin of ear ossicles •malleus & incus-mesoderm of 1st branchial arch •stapes-mesoderm of 2nd branchial arch *Tensor tympani mus.- CN V *Stapedius - CN VII
  • 21. Development of the External Ear Pinna - mesenchyme of 1st &2nd branchial arches:2nd mo. auricular hillock enlargement(asymmetry) External auditory meatus - inward expansion of the 1st branchial cleft 3rd-meatal plug(solid epith. plate) 7th-dissolution of meatal plug
  • 22. Lateral view of the head showing the six auricular hillocks surrounding the dorsal end of the 1st pharyngeal cleft
  • 23. Congenital malformation of the ear •Congenital deafness-inner ear deafness(rubella),middle ear deafness (1st & 2nd arches),agenesis of external ear •Auricular anomalies