2. IVF(In-Vitro Fertilization)
IVF is also known as Test Tube Baby process.
IVF is a process of artificially fertilization of Ovarian
egg.
Fertilization process takes place outside the mother’s
body.
This process takes place via Insemination
3. Insemination
It can be done by two ways:
Using father sperms
Using donor sperms.
(As requirement of couple )
5. EVALUATION
For IVF treatment, couples are advised for certain
investigations.
Ultrasound, for checking condition of ovaries and uterus.
Semen analysis and culture for other problems.
Abnormality test must be carried before IVF procedure.
Evaluation complete—procedure initiates.
6. DOWN REGULATION
Process starts on 21st day of month before IVF cycle.
Blood Investigation for checking LH,FSH and E2
hormones to confirm down regulation.
7. OVULATION INDUCTION
This process depends on patient’s certain conditions
Age
Hormonal problems
Local protocols
FSH or HMG injections are given till desired follicles
size.
8. MONITORING
Cycle is monitored to check growth of eggs and
thickness of endometrium by ultrasound.
Sometimes estrogen level test is done by blood test.
9. EGG PICKUP
When egg reached at desired size, an injection is given
for final maturation(HCG).
Ovum pickup is planned after 35-36 hrs process under
sedation.
With ultrasound, eggs are extracted from follicles with
the help of fine needle.
This process takes 20 min.
10. ICSI
When eggs are retrieved from group of cells, they are
aspirated and after keeping them in incubator they are
ready for fertilization.
IVF/ICSI fertilization process are decided by
embryologist.
In case of poor count and motility ICSI is performed.
TESA/PESA is done for removing sperms from testis.
Then the embryos are left to grow in the controlled
environment of incubator for 2-5 days.
11. EMBROYO TRANSFER
Embryologist assess the quality of embryos and
decides about embryo transfer.
With the help of soft cathedra embryos are placed in
the womb.
After some rest patient can go home.
12. EMBRYO FREEZING
Extra embryos are frozen in liquid nitrogen for
preserving them for years.
Embryos are frozen because the transfer is electively
planned as endrotrium or lining of uterus or patient
has OHSS(ovarian hyper simulation syndrome).
13. EMBROYO HATCHING
In this, outer lining of embryos is treated with either
laser or with certain chemicals.
This process is used to make outer lining more sticky
and more adhesive to lining of womb.
It is effective in older women, in case of failures and
weak lining of womb.
14. IUI(IntraUterine Insemination)
Most commonly used assisted reproductive technique.
Safe, cost effective and non invasive method.
Semen of husband or donor is clinically washed to
improve its fertilization capability and injected into
womb.
15. IUI INDICATIONS
Cervical factors
Mild-moderate male sub-fertility
Unexplained infertility
Immunological factors
An-Ovulation
Endometriosis
Male anatomical defects
Psycosexual disorder-erection ejaculation related
problems
16. IUI INDICATIONS
Genetic, hereditary problems
Severe sperm defects
Contraindications
Several tubal defects
Severe semen abnormalities
Pelvic mass or uterine cavity distortion
17. EVALUATION
Proper timing and proper patient selection of IUI is
essential.
Detailed clinical history and physical examination of
both partners is required.
If any abnormalities is suspected evaluation of
hormonal problems are carried out.
18. IUI LAB
Any center doing IUI must have
TVS facility
Semen collection area
Semen preparation lab with laminar hood, centrifuge
, compound microscope, co2 incubator, CO2
cylinders, semen fertility and storage facility.
Insemination area
19. SUCCESS RATE
Based on age of patient and semen varies from 6-28%
IUI is a very simple and safe procedure but certain
problems may arise:
Trauma to cervix
Infection
Cramps or pain
20.
Contact Us
Dr. Sumita Prabhakar
CMI Hospital, 54, Haridwar Road, Dehradun.
Uttarakhand, India. PIN:248001
Phone: 0135-6542172, 0135-2520042, 2720142, 2720238
Mob: -
Email: sumitaprabhakar@gmail.com