The HRB Clinical Research Coordination Ireland (HRB CRCI) provides support and coordination for multicenter clinical research activities in Ireland. It is co-funded by several organizations and collaborates with clinical research facilities and centers. The HRB CRCI aims to streamline clinical trial feasibility processes, improve study start-up timelines, and enhance quality standards nationally. Key services include signposting researchers, coordinating study feasibility assessments, and establishing quality oversight working groups. The goal is to facilitate innovative, high-quality clinical research across Ireland for the benefit of public health.