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DISEASE DRUG OF CHOICE
Anthrax Penicillin G
Gas gangrene Penicillin G
Leptospira Penicillin G
Meningococcus Penicillin G
Rat bite fever Penicillin G
Streptococcus Penicillin G
Syphilis Penicillin G
Yaws Penicillin G
Extraintestinal/Intestinal
symptomatic Amoeba
Metronidazole
Extraintestinal/Intestinal
Asymptomatic Amoeba
Paromomycin
Aspergillus Voriconazole
Bacterial vaginosis Metronidazole
Trichomoniasis Metronidazole
Tetanus Metronidazole
Bacteroides Metronidazole
Borrelia Doxycycline
Brucella Doxycycline
Chlamydia Doxycycline
Cholera Doxycycline
Granuloma inguinale Doxycycline
LGV Doxycycline
Rickettsia Doxycycline
Pleurodesis Doxycycline
Pericardiodesis Doxycycline
Chancroid Azithromycin
Legionella Azithromycin
Mycoplasma Azithromycin
Chlamydia and cholera in
pregnancy
Azithromycin
Burn infection Silver sulfadiazine
Campylobacter Erythromycin
Diphtheria Erythromycin
Pertussis Erythromycin
Candida Fluconazole
Coccidial meningitis Fluconazole
Chagas disease Benznidazole
Clostridium difficile Vancomycin
Cryptococcus Amphotericin B
Kala azar Amphotericin B
mucormycosis Amphotericin B
Dermatophytes Terbinafine except T.capitis
Tinea capitis Griseofulvin
E.Coli Ceftriaxone
Gonococcus Ceftriaxone
HACEK organism Ceftriaxone
H.Influenzae Ceftriaxone
Klebsiella Ceftriaxone
Resistant typhoid Ceftriaxone
Giardia Tinidazole > Metronidazole
Gonococcus Ceftriaxone
Hepatitis B Entecavir
Hepatitis C Peg Interferon @
H.Pylori Amoxicillin + Clarithromycin + PPI
InfluenzaA Amantadine
Amantadine Resistance –
Oseltamavir
Influenza B
Bird flu
Oseltamavir > Zanamavir
Cutaneous Leishmania Sodium stibogluconate
Visceral Leishmania( Kala azar) Amphotericin B
Listeria Ampicillin > Cotrimoxazole
Meningococcus Prophylaxis Rifampicin
Shigella FQs
Mycobacterium Avium complex Clarithromycin + Ethambutol
Plague Gentamicin
Pneumocystis Cotrimoxazole
Toxoplasma Sulfadiaine + Pyrimethamine
Pregnancy- Spiramycin
Scabies Permethrin Cream
Doc infections
Doc infections
Doc infections
Doc infections
Doc infections
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Doc infections

  • 1. DISEASE DRUG OF CHOICE Anthrax Penicillin G Gas gangrene Penicillin G Leptospira Penicillin G Meningococcus Penicillin G Rat bite fever Penicillin G Streptococcus Penicillin G Syphilis Penicillin G Yaws Penicillin G Extraintestinal/Intestinal symptomatic Amoeba Metronidazole Extraintestinal/Intestinal Asymptomatic Amoeba Paromomycin
  • 2. Aspergillus Voriconazole Bacterial vaginosis Metronidazole Trichomoniasis Metronidazole Tetanus Metronidazole Bacteroides Metronidazole Borrelia Doxycycline Brucella Doxycycline Chlamydia Doxycycline Cholera Doxycycline Granuloma inguinale Doxycycline LGV Doxycycline Rickettsia Doxycycline
  • 3. Pleurodesis Doxycycline Pericardiodesis Doxycycline Chancroid Azithromycin Legionella Azithromycin Mycoplasma Azithromycin Chlamydia and cholera in pregnancy Azithromycin Burn infection Silver sulfadiazine Campylobacter Erythromycin Diphtheria Erythromycin Pertussis Erythromycin Candida Fluconazole Coccidial meningitis Fluconazole
  • 4. Chagas disease Benznidazole Clostridium difficile Vancomycin Cryptococcus Amphotericin B Kala azar Amphotericin B mucormycosis Amphotericin B Dermatophytes Terbinafine except T.capitis Tinea capitis Griseofulvin E.Coli Ceftriaxone Gonococcus Ceftriaxone HACEK organism Ceftriaxone H.Influenzae Ceftriaxone Klebsiella Ceftriaxone
  • 5. Resistant typhoid Ceftriaxone Giardia Tinidazole > Metronidazole Gonococcus Ceftriaxone Hepatitis B Entecavir Hepatitis C Peg Interferon @ H.Pylori Amoxicillin + Clarithromycin + PPI InfluenzaA Amantadine Amantadine Resistance – Oseltamavir Influenza B Bird flu Oseltamavir > Zanamavir
  • 6. Cutaneous Leishmania Sodium stibogluconate Visceral Leishmania( Kala azar) Amphotericin B Listeria Ampicillin > Cotrimoxazole Meningococcus Prophylaxis Rifampicin Shigella FQs Mycobacterium Avium complex Clarithromycin + Ethambutol Plague Gentamicin Pneumocystis Cotrimoxazole Toxoplasma Sulfadiaine + Pyrimethamine Pregnancy- Spiramycin Scabies Permethrin Cream