Physical education aims to promote overall development through physical activity. Physical fitness refers to the body's ability for its systems to work efficiently to perform daily activities and be healthy. It means having enough energy to meet responsibilities at home and enjoy leisure activities. A physically fit person can respond effectively to normal life situations like chores, work, and hobbies. Physical fitness provides many benefits like boosting health, prolonging life, aiding growth and development, and promoting mental wellness. It also saves on healthcare costs long-term by preventing disease and injury. Different types of exercise like cardiovascular, anaerobic, flexibility, and strength building all contribute to physical fitness.
Physical fitness is a state of health and well-being and, more specifically, the ability to perform aspects of sports, occupations and daily activities. Physical fitness is generally achieved through proper nutrition, moderate-vigorous physical exercise, and sufficient rest.
Before the industrial revolution, fitness was defined as the capacity to carry out the day’s activities without undue fatigue. However, with automation and changes in lifestyles physical fitness is now considered a measure of the body's ability to function efficiently and effectively in work and leisure activities, to be healthy, to resist hypo kinetic diseases, and to meet emergency situations.
The document discusses various components of physical fitness, health, and wellness. It defines physical fitness as the ability to perform daily tasks vigorously and with alertness without undue fatigue. Physical fitness has two main components - general fitness involving overall health and well-being, and specific fitness referring to the ability to perform certain sports or tasks. Key aspects of physical fitness include cardiovascular endurance, muscular strength, endurance, and flexibility. Health-related fitness focuses on components like cardiovascular health, strength, and body composition. Wellness additionally encompasses social, emotional, spiritual, nutritional, and financial health dimensions.
The document outlines steps for assessing a family's health-related fitness: conducting fitness tests; identifying physical activity habits; assessing strengths and weaknesses in components of health-related fitness; performing exercises to improve cardiovascular and muscular fitness; demonstrating fitness regularly; explaining the purpose of activities; and designing family physical activities. It also defines fitness and divides physical fitness into health-related and skill-related components.
1) Physical fitness includes cardiovascular fitness, strength, muscular endurance, flexibility, and body composition, and it provides health benefits like disease prevention and improved mood and academics.
2) Physical activity includes sports, dance, and daily activities, while exercise is physical activity done specifically to improve fitness.
3) Physical fitness has both health-related components like cardiovascular fitness and strength as well as skill-related components like agility, balance, power, reaction time, and speed that are important for sports.
This document discusses the benefits of physical fitness and activity. It defines physical fitness as the ability of the body to work efficiently and carry out daily tasks with energy to spare. The benefits of physical activity include improved physical and mental health, reduced risk of disease, better academic performance, and an enhanced ability to enjoy life. Maintaining physical fitness requires regular exercise to strengthen cardiovascular health, muscles, flexibility, and maintain a healthy body composition and weight. An active lifestyle contributes significantly to overall wellness.
Physical fitness has both health-related and skill-related components. Health-related fitness focuses on cardiorespiratory endurance, muscular strength and endurance, flexibility, and body composition in order to promote health and prevent disease. The four main components of health-related fitness are cardiovascular fitness, muscular strength and endurance, flexibility, and body composition. Improving health-related fitness provides numerous health benefits such as decreasing risk of disease, improving bone and cardiovascular health, and increasing energy levels.
Physical education aims to promote overall development through physical activity. Physical fitness refers to the body's ability for its systems to work efficiently to perform daily activities and be healthy. It means having enough energy to meet responsibilities at home and enjoy leisure activities. A physically fit person can respond effectively to normal life situations like chores, work, and hobbies. Physical fitness provides many benefits like boosting health, prolonging life, aiding growth and development, and promoting mental wellness. It also saves on healthcare costs long-term by preventing disease and injury. Different types of exercise like cardiovascular, anaerobic, flexibility, and strength building all contribute to physical fitness.
Physical fitness is a state of health and well-being and, more specifically, the ability to perform aspects of sports, occupations and daily activities. Physical fitness is generally achieved through proper nutrition, moderate-vigorous physical exercise, and sufficient rest.
Before the industrial revolution, fitness was defined as the capacity to carry out the day’s activities without undue fatigue. However, with automation and changes in lifestyles physical fitness is now considered a measure of the body's ability to function efficiently and effectively in work and leisure activities, to be healthy, to resist hypo kinetic diseases, and to meet emergency situations.
The document discusses various components of physical fitness, health, and wellness. It defines physical fitness as the ability to perform daily tasks vigorously and with alertness without undue fatigue. Physical fitness has two main components - general fitness involving overall health and well-being, and specific fitness referring to the ability to perform certain sports or tasks. Key aspects of physical fitness include cardiovascular endurance, muscular strength, endurance, and flexibility. Health-related fitness focuses on components like cardiovascular health, strength, and body composition. Wellness additionally encompasses social, emotional, spiritual, nutritional, and financial health dimensions.
The document outlines steps for assessing a family's health-related fitness: conducting fitness tests; identifying physical activity habits; assessing strengths and weaknesses in components of health-related fitness; performing exercises to improve cardiovascular and muscular fitness; demonstrating fitness regularly; explaining the purpose of activities; and designing family physical activities. It also defines fitness and divides physical fitness into health-related and skill-related components.
1) Physical fitness includes cardiovascular fitness, strength, muscular endurance, flexibility, and body composition, and it provides health benefits like disease prevention and improved mood and academics.
2) Physical activity includes sports, dance, and daily activities, while exercise is physical activity done specifically to improve fitness.
3) Physical fitness has both health-related components like cardiovascular fitness and strength as well as skill-related components like agility, balance, power, reaction time, and speed that are important for sports.
This document discusses the benefits of physical fitness and activity. It defines physical fitness as the ability of the body to work efficiently and carry out daily tasks with energy to spare. The benefits of physical activity include improved physical and mental health, reduced risk of disease, better academic performance, and an enhanced ability to enjoy life. Maintaining physical fitness requires regular exercise to strengthen cardiovascular health, muscles, flexibility, and maintain a healthy body composition and weight. An active lifestyle contributes significantly to overall wellness.
Physical fitness has both health-related and skill-related components. Health-related fitness focuses on cardiorespiratory endurance, muscular strength and endurance, flexibility, and body composition in order to promote health and prevent disease. The four main components of health-related fitness are cardiovascular fitness, muscular strength and endurance, flexibility, and body composition. Improving health-related fitness provides numerous health benefits such as decreasing risk of disease, improving bone and cardiovascular health, and increasing energy levels.
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This document discusses the importance of fitness and its benefits. It defines physical fitness as the body's ability to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has many health benefits and includes both health-related and skill-related components. Health-related components are cardiovascular endurance, strength, flexibility, and body composition, while skill-related components include agility, balance, power, reaction time, and speed. Maintaining a lifetime of physical activity and fitness requires regular self-assessment and planning.
This document discusses the importance of fitness and its impact on physical, mental, and social health. It defines physical fitness as the body's ability to work efficiently and enjoy daily activities as well as respond to emergencies. Physical activity includes sports, dance, and work activities, while exercise is physical activity done specifically to improve fitness. Regular physical activity can prevent disease and illness while improving appearance, mood, and academic performance. Physical fitness has two main components - health-related fitness involving cardiovascular endurance, strength, flexibility, and body composition, and skill-related fitness involving agility, balance, power, reaction time, and speed. Maintaining a lifetime of physical activity is key to lifelong fitness.
Fitness refers to a state of physical and mental well-being that is achieved through regular physical activity, exercise, and a balanced lifestyle. It encompasses various components, including cardiovascular endurance, muscular strength and endurance, flexibility, body composition, and overall health.
This document discusses the importance of fitness and its benefits. It defines physical fitness as the body's ability to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has many health benefits and includes both health-related and skill-related components. Health-related components are cardiovascular endurance, strength, flexibility, and body composition, while skill-related components include agility, balance, power, reaction time, and speed. Maintaining a lifetime of physical activity and fitness requires regular self-assessment and planning.
This document discusses the importance of fitness and its benefits. It defines physical fitness as the body's ability to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has both health-related and skill-related components that benefit overall health, wellness, and sports performance. It emphasizes that regular physical activity and exercise are important to maintain lifetime fitness.
Fitness refers to a state of physical well-being and the ability to perform physical activities without undue fatigue. It involves various components, including cardiovascular endurance, muscular strength and endurance, flexibility, and body composition.
The document discusses the importance of physical fitness and health. It defines health-related physical fitness as having enough energy to complete daily tasks without fatigue and having reserved energy for emergencies. It states that physical fitness is important for health because it reduces the risk of illness, allowing one to perform daily activities. The document outlines the five components of health-related fitness as cardiorespiratory fitness, muscular strength and endurance, flexibility, and body composition.
This document discusses physical fitness and its benefits. It defines physical fitness as the body's ability to function efficiently and be able to handle daily tasks as well as emergencies. Regular physical activity and exercise can improve physical fitness in areas like cardiovascular health, strength, flexibility, and body composition. This physical fitness leads to health benefits like reduced disease risk and improved mood and academic performance. The document also outlines the components of health-related and skill-related physical fitness.
Staying physically fit through exercise provides numerous mental and physical health benefits such as strengthening the heart, reducing depression, and promoting an overall healthy and energetic lifestyle. Physical fitness is comprised of various components including cardiovascular endurance, muscular strength, flexibility, and body composition that allow a person to develop an efficient fitness routine. Maintaining physical fitness results in a long and healthy life with benefits like preventing excess body fat, reduced illness, strong bones, and increased energy through proper diet, lifestyle habits, and regular exercise.
Physical fitness is a state of health and well-being and, more specifically, the ability to perform aspects of sports, occupations and daily activities. Physical fitness is generally achieved through proper nutrition, moderate-vigorous physical exercise.
Example benefits of-fitness-presentationjoyeluvsfit
This document discusses the importance of physical fitness and its many benefits. It defines physical fitness as the ability of the body to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has both health-related and skill-related components, with health-related fitness including cardiovascular endurance, strength, flexibility, and body composition. The document outlines different aspects of skill-related fitness like agility, balance, power, reaction time and speed that are important for different sports. Maintaining regular physical activity and fitness provides significant health, wellness and quality of life benefits.
This document discusses health, fitness, and nutrition. It defines physical fitness as the ability of the body systems to work efficiently to carry out daily activities and respond to emergencies. Physical fitness has two parts: health-related fitness (cardiovascular endurance, strength, flexibility, etc.) and skill-related fitness (agility, balance, power, reaction time, speed). The document also discusses nutrition, explaining that a balanced diet from the major food groups provides vitamins, minerals and energy for growth. Maintaining fitness and a nutritious diet contributes to overall health and well-being.
The document discusses the importance of physical fitness and its many benefits. It defines physical fitness as the ability of the body's systems to work efficiently. Regular physical activity can help prevent disease and improve overall health, wellness, and quality of life. Physical fitness has both health-related and skill-related components that include cardiovascular endurance, muscular strength, flexibility, and more. Maintaining a lifetime of physical fitness requires regular self-assessment and planning to sustain activity levels.
Physical activity and exercise are important for maintaining good health and reducing the risk of diseases. There are five components of physical fitness: cardiorespiratory endurance, muscular strength, muscular endurance, flexibility, and body composition. Engaging in regular physical activity can provide health benefits like reducing the risk of obesity, heart disease, and diabetes, as well as improving mood, quality of life, and physical fitness. Making time for moderate physical activity most days of the week is key to achieving a healthy lifestyle with good nutrition.
Physical fitness is important for overall health and well-being. It allows the body to perform daily tasks without undue fatigue and reduces the risk of diseases. Physical fitness involves cardiovascular endurance, muscular strength and endurance, flexibility, and body composition. Regular exercise through activities like running, biking, swimming and team sports improves all aspects of physical fitness and provides advantages like reduced disease risk, stronger muscles and joints, better weight and stress management.
Physical fitness refers to the body's ability to function efficiently and perform daily tasks. It involves the cardiovascular system, muscles, flexibility, body composition, and overall health. There are six components of physical fitness - muscular strength, endurance, cardiovascular endurance, flexibility, body composition, and organic vigor. Regular exercise can improve overall health, reduce stress, improve quality of life, and reduce the risk of disease and injury.
The document describes two men, Mr. Chopin and Eric, who are both 36 years old with similar backgrounds but different levels of fitness and health. Mr. Chopin weighs 407 lbs, struggles with daily activities, and has health issues like hypertension and diabetes. Eric is in great shape, feels energetic, and engages in exercise. It is revealed that Eric Chopin underwent a weight loss program, lost over 200 lbs, and gained a new life, showing the power of fitness to improve health and well-being.
Physical fitness is the ability to live a healthy, productive life through correct exercise, nutrition, and rest. It allows the body to function efficiently during work and leisure activities and resist diseases from a sedentary lifestyle. There are two categories of physical fitness parameters: skill-related including agility, balance, and speed and health-related such as cardiovascular endurance, flexibility, and strength. Maintaining physical fitness reduces risks from hypokinetic diseases like obesity that result from too little physical activity and a sedentary lifestyle.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
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Similar to devesh-fit-presentation.pptx DEVESH BAHTT
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This document discusses the importance of fitness and its benefits. It defines physical fitness as the body's ability to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has many health benefits and includes both health-related and skill-related components. Health-related components are cardiovascular endurance, strength, flexibility, and body composition, while skill-related components include agility, balance, power, reaction time, and speed. Maintaining a lifetime of physical activity and fitness requires regular self-assessment and planning.
This document discusses the importance of fitness and its impact on physical, mental, and social health. It defines physical fitness as the body's ability to work efficiently and enjoy daily activities as well as respond to emergencies. Physical activity includes sports, dance, and work activities, while exercise is physical activity done specifically to improve fitness. Regular physical activity can prevent disease and illness while improving appearance, mood, and academic performance. Physical fitness has two main components - health-related fitness involving cardiovascular endurance, strength, flexibility, and body composition, and skill-related fitness involving agility, balance, power, reaction time, and speed. Maintaining a lifetime of physical activity is key to lifelong fitness.
Fitness refers to a state of physical and mental well-being that is achieved through regular physical activity, exercise, and a balanced lifestyle. It encompasses various components, including cardiovascular endurance, muscular strength and endurance, flexibility, body composition, and overall health.
This document discusses the importance of fitness and its benefits. It defines physical fitness as the body's ability to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has many health benefits and includes both health-related and skill-related components. Health-related components are cardiovascular endurance, strength, flexibility, and body composition, while skill-related components include agility, balance, power, reaction time, and speed. Maintaining a lifetime of physical activity and fitness requires regular self-assessment and planning.
This document discusses the importance of fitness and its benefits. It defines physical fitness as the body's ability to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has both health-related and skill-related components that benefit overall health, wellness, and sports performance. It emphasizes that regular physical activity and exercise are important to maintain lifetime fitness.
Fitness refers to a state of physical well-being and the ability to perform physical activities without undue fatigue. It involves various components, including cardiovascular endurance, muscular strength and endurance, flexibility, and body composition.
The document discusses the importance of physical fitness and health. It defines health-related physical fitness as having enough energy to complete daily tasks without fatigue and having reserved energy for emergencies. It states that physical fitness is important for health because it reduces the risk of illness, allowing one to perform daily activities. The document outlines the five components of health-related fitness as cardiorespiratory fitness, muscular strength and endurance, flexibility, and body composition.
This document discusses physical fitness and its benefits. It defines physical fitness as the body's ability to function efficiently and be able to handle daily tasks as well as emergencies. Regular physical activity and exercise can improve physical fitness in areas like cardiovascular health, strength, flexibility, and body composition. This physical fitness leads to health benefits like reduced disease risk and improved mood and academic performance. The document also outlines the components of health-related and skill-related physical fitness.
Staying physically fit through exercise provides numerous mental and physical health benefits such as strengthening the heart, reducing depression, and promoting an overall healthy and energetic lifestyle. Physical fitness is comprised of various components including cardiovascular endurance, muscular strength, flexibility, and body composition that allow a person to develop an efficient fitness routine. Maintaining physical fitness results in a long and healthy life with benefits like preventing excess body fat, reduced illness, strong bones, and increased energy through proper diet, lifestyle habits, and regular exercise.
Physical fitness is a state of health and well-being and, more specifically, the ability to perform aspects of sports, occupations and daily activities. Physical fitness is generally achieved through proper nutrition, moderate-vigorous physical exercise.
Example benefits of-fitness-presentationjoyeluvsfit
This document discusses the importance of physical fitness and its many benefits. It defines physical fitness as the ability of the body to work efficiently and carry out daily activities while having enough energy to handle emergencies. Physical fitness has both health-related and skill-related components, with health-related fitness including cardiovascular endurance, strength, flexibility, and body composition. The document outlines different aspects of skill-related fitness like agility, balance, power, reaction time and speed that are important for different sports. Maintaining regular physical activity and fitness provides significant health, wellness and quality of life benefits.
This document discusses health, fitness, and nutrition. It defines physical fitness as the ability of the body systems to work efficiently to carry out daily activities and respond to emergencies. Physical fitness has two parts: health-related fitness (cardiovascular endurance, strength, flexibility, etc.) and skill-related fitness (agility, balance, power, reaction time, speed). The document also discusses nutrition, explaining that a balanced diet from the major food groups provides vitamins, minerals and energy for growth. Maintaining fitness and a nutritious diet contributes to overall health and well-being.
The document discusses the importance of physical fitness and its many benefits. It defines physical fitness as the ability of the body's systems to work efficiently. Regular physical activity can help prevent disease and improve overall health, wellness, and quality of life. Physical fitness has both health-related and skill-related components that include cardiovascular endurance, muscular strength, flexibility, and more. Maintaining a lifetime of physical fitness requires regular self-assessment and planning to sustain activity levels.
Physical activity and exercise are important for maintaining good health and reducing the risk of diseases. There are five components of physical fitness: cardiorespiratory endurance, muscular strength, muscular endurance, flexibility, and body composition. Engaging in regular physical activity can provide health benefits like reducing the risk of obesity, heart disease, and diabetes, as well as improving mood, quality of life, and physical fitness. Making time for moderate physical activity most days of the week is key to achieving a healthy lifestyle with good nutrition.
Physical fitness is important for overall health and well-being. It allows the body to perform daily tasks without undue fatigue and reduces the risk of diseases. Physical fitness involves cardiovascular endurance, muscular strength and endurance, flexibility, and body composition. Regular exercise through activities like running, biking, swimming and team sports improves all aspects of physical fitness and provides advantages like reduced disease risk, stronger muscles and joints, better weight and stress management.
Physical fitness refers to the body's ability to function efficiently and perform daily tasks. It involves the cardiovascular system, muscles, flexibility, body composition, and overall health. There are six components of physical fitness - muscular strength, endurance, cardiovascular endurance, flexibility, body composition, and organic vigor. Regular exercise can improve overall health, reduce stress, improve quality of life, and reduce the risk of disease and injury.
The document describes two men, Mr. Chopin and Eric, who are both 36 years old with similar backgrounds but different levels of fitness and health. Mr. Chopin weighs 407 lbs, struggles with daily activities, and has health issues like hypertension and diabetes. Eric is in great shape, feels energetic, and engages in exercise. It is revealed that Eric Chopin underwent a weight loss program, lost over 200 lbs, and gained a new life, showing the power of fitness to improve health and well-being.
Physical fitness is the ability to live a healthy, productive life through correct exercise, nutrition, and rest. It allows the body to function efficiently during work and leisure activities and resist diseases from a sedentary lifestyle. There are two categories of physical fitness parameters: skill-related including agility, balance, and speed and health-related such as cardiovascular endurance, flexibility, and strength. Maintaining physical fitness reduces risks from hypokinetic diseases like obesity that result from too little physical activity and a sedentary lifestyle.
Similar to devesh-fit-presentation.pptx DEVESH BAHTT (20)
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
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Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
There are a wide variety of vectors used to deliver DNA or oligo nucleotides into mammalian cells, either in vitro or in vivo.
The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
Spontaneous Bacterial Peritonitis - Pathogenesis , Clinical Features & Manage...Jim Jacob Roy
In this presentation , SBP ( spontaneous bacterial peritonitis ) , which is a common complication in patients with cirrhosis and ascites is described in detail.
The reference for this presentation is Sleisenger and Fordtran's Gastrointestinal and Liver Disease Textbook ( 11th edition ).
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14...Donc Test
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
2. HEALTH
Health and fitness are important in every
day living, and being healthy means more
than not being ill or sick.
There are many parts of a person life which
contributes to their good health.
4. FITNESS
Fitness is defined as being in good physical
shape or being suitable for a specific task
or purpose. An example of fitness is the
status of your physical condition resulting
from exercise and proper nutrition.
5. WHAT MAKE SOMEONE FIT?
• AGE
• SEX
• SOMATOTYPE
• POWER
• FOUR S’S
• STRENGTH
• SUPPLENESS
(FLEXIBLITY)
• STAMINA
(ENDURANCE)
• SPEED
6. PHYSICAL FITNESS
• Physical fitness is
the ability of the
lungs, heart,
muscles and joints
to perform well.
• Regular physical
activity promotes
physical fitness.
A GOOD WAY TO REMEMBER
THIS IS USING PS:
• POWER
• SPEED
• STAMINA(endurance)
• STRENGTH
• SUPPLENESS(flexibility)
9. SPEED
This is the ability to cover
distance or movement in a
short time.
This ability is an
important part of most
sports.
10. STRENGTH
This is the ability of the
muscles to exhert a force
as they contract.
There are 3 types of
Strength
Dynamic
Explosive
Static
11. SUPPLENESS
The range of movement at the
joints is the flexibility,
mobility or suppleness of the
person.
Flexibility is important in
reducing the change of
muscles pulls.