Dementia is a condition where you experience a decline in your mental abilities, impacting your daily life. It can lead to difficulties with memory, thinking, and planning. The progression of dementia varies from person to person, with some individuals remaining stable for years, while others may experience a rapid decline. The important point is prevention for dementia and what one can do to manage it. Prevention for dementia can be easily acquired if we do some activities that will be mentioned in this article.
5 tips to care neurological disorder patientshealthheal
Neurological disorders are diseases of the brain, spine and the nerves that connect them.For more information click here, http://healthheal.in/neurological%20care%20bangalore%20chennai%20india.html
5 tips to care neurological disorder patientshealthheal
Neurological disorders are diseases of the brain, spine and the nerves that connect them.For more information click here, http://healthheal.in/neurological%20care%20bangalore%20chennai%20india.html
The word dementia describes a set of symptoms that can include memory loss and difficulties with thinking, problem-solving or language. In vascular dementia, these symptoms occur when the brain is damaged because of problems with the supply of blood to the brain.
Alzheimer's disease is a progressive, degenerative disorder that attacks the brain's nerve cells, resulting in loss of memory, imagination and speaking skills, and behavioural changes. Alzheimer's disease is the most common cause of dementia, or loss of intellectual function, among people aged 65 and older.
The word dementia describes a set of symptoms that can include memory loss and difficulties with thinking, problem-solving or language. In vascular dementia, these symptoms occur when the brain is damaged because of problems with the supply of blood to the brain.
Alzheimer's disease is a progressive, degenerative disorder that attacks the brain's nerve cells, resulting in loss of memory, imagination and speaking skills, and behavioural changes. Alzheimer's disease is the most common cause of dementia, or loss of intellectual function, among people aged 65 and older.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. Dementia 101
In recent years, more older adults have been experiencing dementia. Let us first define what
dementia is so we can understand it more.
Dementia is a condition where you experience a decline in your mental abilities, impacting
your daily life. It can lead to difficulties with memory, thinking, and planning. The progression
of dementia varies from person to person, with some individuals remaining stable for years,
while others may experience a rapid decline. The important point is prevention for dementia
and what one can do to manage it. Prevention for dementia can be easily acquired if we
do some activities that will be mentioned in this article.
Causes of Dementia
Past studies have explored the causes of this disease. Are you living with Dementia?Then
you need to know the common causes and types of dementia which are:
• Alzheimer’s dementia, also referred to as Major Neurocognitive Disorder due to
Alzheimer’s disease
• Vascular Dementia
Parkinson’s Dementia
2. Frontotemporal Dementia
• Lewy Body Dementia
There are also less common causes of dementia which includes:
• Dementia due to multiple etiologies
• Dementia due to traumatic brain injury
• Dementia due to another medical condition
• Dementia due to substance/medication use
• Dementia due to HIV infection
• Huntington’s dementia
• Dementia due to Prion Disease
This was discussed by Dr Rathi Mahendran at our Living with Dementia webinar: "Am I
at risk of Dementia?”
Types of Dementia
The types of dementia can be seen below together with their brief description:
Types of dementia Brief Description
Alzheimer’s dementia
• Alzheimer’s dementia has a very gradual progression
of cognitive and functional decline.
It affects you slowly, possibly over 8 to 10 years.
• The Amnestic type involves loss of memory and
learning ability.
• The non-amnestic type involves loss of vision, spacial
awareness, and speech.
Vascular dementia • Vascular dementia often times happen due to
impacted blood vessels in the brain.
• Often caused by brain damage from strokes or heart-
related issues, and sometimes alongside Alzheimer’s
disease.
Parkinson’s dementia
• Starts with Parkinson’s disease and later leads to
Dementia
3. Frontotemporal dementia
-Frontotemporal dementia (FTD) is a group of brain diseases
that affect nerve cells in the frontal and temporal lobes. Unlike
Alzheimer's, it often doesn't involve amyloid plaques, and it
can be genetic, with symptoms starting between 40 and 65
years old, lasting around 5 to 10 years on average.
Lewy Body dementia
-Dementia with Lewy bodies (DLB) is a common progressive
dementia, often occurring without a family history. It involves
cell damage in the brain's cortex and midbrain, with abnormal
structures called Lewy bodies containing a protein called
alpha-synuclein, but the exact reason for their accumulation is
not yet understood.
Huntington’s disease
• Huntington’s disease is a brain disease where brain
cells break down.
• It is a rare and inherited disease that affects a
person’s functional ability.
• Those with Huntington’s disease often experience
emotional changes, loss of thinking abilities, and
uncontrolled movements.
Normal pressure
hydrocephalus -In the brain, there are chambers called ventricles that hold
fluid called cerebrospinal fluid. Sometimes, too much fluid
gathers in these chambers, causing a condition called normal
pressure hydrocephalus (NPH).
Creutzfeldt-Jakob
disease
-CJD is a rare and deadly brain disorder that typically starts
after age 60, with most patients passing away within a year.
It's thought to be caused by abnormal proteins called prions,
and while most cases occur randomly, a small percentage can
be hereditary, but it's not contagious through the air or casual
contact.
Corticobasal
degeneration
-Corticobasal degeneration (CBD) is a brain problem where
nerve cells die and certain brain areas shrink. People with
CBD have abnormal stuff in their brain cells called tau protein.
It slowly gets worse over about 6 to 8 years.
Mild cognitive impairment
-Mild cognitive impairment is when you have some memory
and thinking problems, but they don't affect your daily life. It's
not a specific disease and can have many different causes,
like dementia.
Prevention For Dementia
4. Now the questions are how can one with dementia be treated and the prevention of
dementia. There are two ways in which dementia can be treated but these are mostly
considered preventive measures and not cures.
Firstly there is the use of medications. Medications can't completely cure dementia, but they
can be used to slow it down a bit. These drugs might make your thinking better, improve your
mood, or help you behave in a more positive way.
Secondly, there is one called Palliative care which is for seriously ill people. It's not about
curing the illness but making life better in body, mind, and spirit.
The care may include:
• Ways to help the person do things on their own and handle daily life for as long as
they can.
• Medicines can't cure dementia, but they might make thinking better, mood happier, or
behaviour calmer.
• When you're diagnosed with dementia, it can bring up emotions like anger and fear.
To help with these feelings, talk to family, friends, or a dementia counsellor. They
can give you support and guidance during this challenging time.
Dementia treatment helps keep the person safe at home with caregiver support. Check-ups
every few months to watch their medicine and how they're doing. If necessary, the family
might think about a special care place later on. Also there is an opportunity to survive,
contact NUS Mind Science Centre to know more about How To Prevent Dementia
Singapore!
5. How to prevent dementia is a common question among old age people. It can be a bit
tricky because we don't always know exactly what causes it. But for some people who have
dementia linked to strokes, there's a chance to slow down the decline by reducing the risks of
heart disease and more strokes in the future. And guess what? These strategies aren't just
for them - they can be good for anyone's overall health:.
How To Prevent Dementia Naturally - H3
• Stay Active: Moving your body with regular exercise, like walking, swimming, or
dancing, can help keep your brain and body in good shape.
• Eat Well: A healthy diet full of fruits, veggies, whole grains, and lean proteins can
give your brain and body the fuel they need.
• Keep Your Heart Healthy: Since heart health is connected to brain health, try to
manage your blood pressure, cholesterol, and blood sugar levels.
• Stay Social: Being around friends and family, and staying engaged with activities
you enjoy, can help your brain stay active and sharp.
• Challenge Your Brain: Keep your mind busy with puzzles, reading, learning new
things, or even playing games.
• Get Enough Sleep: A good night's sleep helps your brain and body recover and
stay healthy.
6. • Manage Stress: Find ways to relax and reduce stress, like through
meditation, deep breathing, or hobbies you enjoy.
Remember, these steps can't guarantee you won't get dementia, but they can help
improve your overall well-being and reduce certain risks.
In conclusion, dementia is a complex condition that mainly affects older individuals. While
there is no cure, treatments aim to slow it down and improve the well-being of patients and
caregivers. Within the broader context of dementia, prevention for dementia plays a
crucial role. Particularly in cases related to strokes, understanding how to prevent dementia
is vital. Strategies such as staying active, eating well, and taking care of heart health can
contribute significantly to this prevention effort. As ongoing research provides hope for
better treatments, it further emphasises the importance of enhancing the lives of people with
dementia and supporting their caregivers.