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Biswajit Chakraborty : biswajitmom@gmail.com
M.Sc., Ph.D. : +91-9433907546
Industrial R&D Experience: 3.70 Years West Bengal, India
Objective: Seeking Challenging and Rewarding assignments in the Field of Research and Development in the field of
Natural Product/Phyto-Chemistry.
Synopsis:
 Seasoned and self-motivated Technical & Quality Management professional backed by strong academic
qualifications (Ph.D. in Natural Product and Medicinal Chemistry) and more than 3 years of experience in the
areas of Testing, Training, Consultation, Analytical Research & Development Herbal products and Environment.
 Responsible for meeting major objectives for the organization, Supervise high-level professionals/ researchers/
scientists as well as students and labors.
 Excellent functional knowledge in initiating and streamlining the facility.
 Strong knowledge, hands on experience, calibration & maintenance of HPLC, HPTLC, Spray Dryer, UV-Vis
spetrophotometer and LC- MS (Water’s Xevo - TQD) and other Laboratory Instruments.
 Possesses an observant attitude with zeal to learn and effectively apply the acquired knowledge for the
achievement of targets.
 Well versed with FSSAI, ISO: 9001-2008, ISO: 9001-2015, Drug Control, etc.
 Having experience as an auditee in ISO: 9001-2008, ISO: 9001-2015 (DNV GL, London, UK) & GLP (Zurich,
Switzerland).
 Well versed with basic computer skills as well as software related with biology.
 Possesses good analytical/interpretation skills.
 Scientific and analytical temper.
Professional Experience:
 Present : Government of West Bengal
 Place : Darjeeling
 Position : Group A Officer
 Designation : Quinologist
 Division : Industrial Chemistry
 Responsibility : Administration of Century Old Govt. Quinine Factory, Mungpoo,
Darjeeling and handling more than 100 labors along with
isolation of bio-active molecules from Cinchona and other
medicinal plants, characterization, quantification and estimation
of the bio actives present and product development
 Total Experience : 1.5 years in Government Quinine Factory as a Quinologist + 2.20
Years as a Scientist-C in a USA based Natural Product Company
namely Natreon Inc.
Professional Capabilities:
 Expertise in isolation of biologically active compounds with the help of Soxhlet apparatus (for hot
extraction) and percolator (for cold extraction), solvent extraction, structure elucidation and
characterization [with the help of Mass, NMR(
1
H,
13
C, 2D technique like COSY, HSQC, HMBC, NOSY)] of the
isolated products from medicinal plants.
 Synthesis of different analogue library based on isolated bio-markers.
 Handling of laboratory instruments.
 Documentation, project outcome report/presentations and content creation.
 Lead role to manage and control hazards into Laboratory [Environmental Health and Safety (EHS)].
Expertise in: Research and Development (R&D):
 Ability to design and optimize new extraction technology and to deliver reproducible data with proven
efficacy.
 Work experience on major class of compounds e.g. Alkaloids, Flavonoids, Terpenes/ Terpenoids and their
Biswajit Chakraborty
glycosides.
 Capable for designing novel steps for the fractionation, refining, purification and isolation of the actives.
 Standardization of extracts through various chromatographic technologies.
Experimental Skills:
 Extraction (solvent-solvent extraction, fractionation and enrichment) and isolation of different secondary
metabolites of plants using chromatographic technologies.
 Scale up of analytical to prep-HPLC methods for isolation and purification of bio active natural products.
 Fingerprinting & marker profiling using various technologies e.g. HPTLC, HPLC with PDA and ELSD
detectors.
 Interpretation of experimental/analytical data: HPLC, FT-IR, UV-Vis spectra, Mass and NMR and 2D NMR
data.
 Hands on experience on Flash Chromatography, HPLC, HPTLC, Spray Dryer, UV-Vis spetrophotometer and
LC- MS (Water’s Xevo - TQD).
Instrument Management:
 FC: Flash Chromatography (Silica gel, C-18, LH-20, Sephadex, Reverse phase C-18)
 HPLC: Semi-preparative & preparative; Data acquisition- LC solution; Empower
 HPTLC: High Performance Thin Layer Chromatography (CAMAG); Data acquisition- WINCATS.
 Spray Dryer
 UV-Vis: Ultraviolet/visible Absorption Spectrophotometer
 pH meter
Core Competencies:
 Analytical Laboratory Management
 Training to Sub-ordinates, University, College Students, and Industrial Persons etc.
 Research and Development
 Food Safety
 Quality Assurance & Quality Control
 Analytical Testing & Development
 Quality management systems
 Technical Operations
 Project Management
 Team Management
 Inventory Management
Educational Profile:
Qualification University/ institute Year of
passing
% (Grade)
Doctor of
Philosophy
(Ph. D.) in
Natural
Product and
Medicinal
Chemistry
CSIR-Indian Institute Of Chemical Biology and Jadavpur
University, Kolkata, West Bengal, India.
Thesis entitle “Synthesis of various analogues based on Andrographolide and
Betulinic acid and evaluation of their anti-cancer potential”
Mentor: Dr. Chinmay Chowdhury & Dr. Nakul Chandra Maiti
2015
(76.5% in
course
work)
1st
M. Sc.
(Specialization
in Organic
Chemistry)
Vidyasagar University; Midnapore; West Bengal, India 2007
62.9
1st
B. Sc
(Chemistry) University of Calcutta, Kolkata, West Bengal, India 2005
52.12
2nd
Personal Details:
 Date of Birth: 31
st
March, 1983
 Sex: Male
 Nationality: Indian
 Marital Status: Married
Publications:
1. A rapid and facile method for the general synthesis of 3-aryl substituted 4,5,6,7- tetrahydro[1,2,3]triazolo[1,5-a]pyrazines and their
ring fused analogues; Chinmay Chowdhury, Sanjukta Mukherjee, Biswajit Chakraborty and Basudeb Achari; Organic &
Biomolecular Chemistry, 2011, 9, 5856-5862. (Impact factor: 3.56)
2. Apoptotic and Autophagic Effects of Sesbania grandiflora Flowers in Human Leukemic Cells; Rajneeta Roy,Deepak Kumar,
Biswajit Chakraborty, Chinmay Chowdhury, Padma Das; PLoS ONE, 2013, 8(8) e71672. (Impact factor: 3.23)
3. Synthesis and biological evaluation of andrographolide analogues as anti-cancer agent’; Ranjan Preet*, BiswajitChakraborty*,
Sumit Siddharth, Purusottam Mohapatra, Dipon Das, Shakti Ranjan Satapathy, Supriya Das, Nakul C.Maiti, Prakas R. Maulik,
Chanakya Nath Kundu and Chinmay Chowdhury; European Journal of Medicinal Chemistry, 2014, 85, 95−106. (* contributed
equally) (Impact factor: 3.45)
4. Induction of apoptosis by a potent Betulinic acid derivative in Human colon carcinoma HT-29 cells; Debasmita Dutta, Ankita
Sarkar, Biswajit Chakraborty, Chinmay Chowdhury and Padma Das; International Journal of Scientific and Research
Publications, 2015, 5(2), 1-5. (Impact factor: 2.07)
5. Synthesis and biological evaluation of a novel betulinic acid derivative as inducer of apoptosis in human coloncarcinoma cells (HT-
29); Biswajit Chakraborty, Debasmita Dutta, Sanjukta Mukherjee, Supriya Das, Nakul C. Maiti,Padma Das and Chinmay
Chowdhury; European Journal of Medicinal Chemistry, 2015, 102, 93-105. (Impact factor: 3.45)
6. A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomaldegradation pathway
in HT-29 cells; Debasmita Dutta, Biswajit Chakraborty, Ankita Sarkar, Chinmay Chowdhury and Padma Das; BMC Cancer,
2016, 16, 23. (Impact factor: 3.36)
7. 14-deoxy-11,12-didehydroandrographolide: A Novel Compound Isolated From Andrographis Paniculata Nees. Induces Robust
Apoptosis In Leukemic Cells. Swadesh Sarkar, Biswajit Chakraborty, Chinmay Chowdhury and Santanu Paul. Pharmacognosy
Phcog Mag, 2019,15, S135-43. (Impact factor: 1.53)
References:
I hereby declare that particulars supplied by me and that all the information’s given are true to the best of my knowledge and belief.
(Signature)
1) Dr. Bikash Chandra Pal
Ex Scientist, Medicinal Chemistry Division
CSIR-Indian Institute of Chemical Biology
Jadavpur, Kolkata-700032, India
E-Mail ID: drbcpal@gmail.com
Phone: +91-9432266279
2) Dr. Basudeb Achari
Ex Scientist, Chemistry Division
CSIR-Indian Institute of Chemical Biology
Jadavpur, Kolkata-700032, India
E-Mail ID: achari.basudeb@gmail.com
Phone: +91-9433001083
3) Dr. Chinmay Chowdhury (Ph.D.
supervisor)
Principal Scientist, Chemistry Division
CSIR-Indian Institute of Chemical Biology
Jadavpur, Kolkata-700032, India
E. Mail ID: chinmay@iicb.res.in or
cchinmay2@yahoo.com
Phone: +91-9007685961
4. Dr. Nakul C. Maiti, (Ph.D. supervisor)
Senior Scientist, Structural Biology and
Bioinformatics Division,
CSIR-Indian Institute of Chemical Biology,
Jadavpur, Kolkata-700032, India.
E. Mail ID: ncmaiti@iicb.res.in
Phone: +91-9432013452

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CV.pdf

  • 1. Biswajit Chakraborty : biswajitmom@gmail.com M.Sc., Ph.D. : +91-9433907546 Industrial R&D Experience: 3.70 Years West Bengal, India Objective: Seeking Challenging and Rewarding assignments in the Field of Research and Development in the field of Natural Product/Phyto-Chemistry. Synopsis:  Seasoned and self-motivated Technical & Quality Management professional backed by strong academic qualifications (Ph.D. in Natural Product and Medicinal Chemistry) and more than 3 years of experience in the areas of Testing, Training, Consultation, Analytical Research & Development Herbal products and Environment.  Responsible for meeting major objectives for the organization, Supervise high-level professionals/ researchers/ scientists as well as students and labors.  Excellent functional knowledge in initiating and streamlining the facility.  Strong knowledge, hands on experience, calibration & maintenance of HPLC, HPTLC, Spray Dryer, UV-Vis spetrophotometer and LC- MS (Water’s Xevo - TQD) and other Laboratory Instruments.  Possesses an observant attitude with zeal to learn and effectively apply the acquired knowledge for the achievement of targets.  Well versed with FSSAI, ISO: 9001-2008, ISO: 9001-2015, Drug Control, etc.  Having experience as an auditee in ISO: 9001-2008, ISO: 9001-2015 (DNV GL, London, UK) & GLP (Zurich, Switzerland).  Well versed with basic computer skills as well as software related with biology.  Possesses good analytical/interpretation skills.  Scientific and analytical temper. Professional Experience:  Present : Government of West Bengal  Place : Darjeeling  Position : Group A Officer  Designation : Quinologist  Division : Industrial Chemistry  Responsibility : Administration of Century Old Govt. Quinine Factory, Mungpoo, Darjeeling and handling more than 100 labors along with isolation of bio-active molecules from Cinchona and other medicinal plants, characterization, quantification and estimation of the bio actives present and product development  Total Experience : 1.5 years in Government Quinine Factory as a Quinologist + 2.20 Years as a Scientist-C in a USA based Natural Product Company namely Natreon Inc. Professional Capabilities:  Expertise in isolation of biologically active compounds with the help of Soxhlet apparatus (for hot extraction) and percolator (for cold extraction), solvent extraction, structure elucidation and characterization [with the help of Mass, NMR( 1 H, 13 C, 2D technique like COSY, HSQC, HMBC, NOSY)] of the isolated products from medicinal plants.  Synthesis of different analogue library based on isolated bio-markers.  Handling of laboratory instruments.  Documentation, project outcome report/presentations and content creation.  Lead role to manage and control hazards into Laboratory [Environmental Health and Safety (EHS)]. Expertise in: Research and Development (R&D):  Ability to design and optimize new extraction technology and to deliver reproducible data with proven efficacy.  Work experience on major class of compounds e.g. Alkaloids, Flavonoids, Terpenes/ Terpenoids and their Biswajit Chakraborty
  • 2. glycosides.  Capable for designing novel steps for the fractionation, refining, purification and isolation of the actives.  Standardization of extracts through various chromatographic technologies. Experimental Skills:  Extraction (solvent-solvent extraction, fractionation and enrichment) and isolation of different secondary metabolites of plants using chromatographic technologies.  Scale up of analytical to prep-HPLC methods for isolation and purification of bio active natural products.  Fingerprinting & marker profiling using various technologies e.g. HPTLC, HPLC with PDA and ELSD detectors.  Interpretation of experimental/analytical data: HPLC, FT-IR, UV-Vis spectra, Mass and NMR and 2D NMR data.  Hands on experience on Flash Chromatography, HPLC, HPTLC, Spray Dryer, UV-Vis spetrophotometer and LC- MS (Water’s Xevo - TQD). Instrument Management:  FC: Flash Chromatography (Silica gel, C-18, LH-20, Sephadex, Reverse phase C-18)  HPLC: Semi-preparative & preparative; Data acquisition- LC solution; Empower  HPTLC: High Performance Thin Layer Chromatography (CAMAG); Data acquisition- WINCATS.  Spray Dryer  UV-Vis: Ultraviolet/visible Absorption Spectrophotometer  pH meter Core Competencies:  Analytical Laboratory Management  Training to Sub-ordinates, University, College Students, and Industrial Persons etc.  Research and Development  Food Safety  Quality Assurance & Quality Control  Analytical Testing & Development  Quality management systems  Technical Operations  Project Management  Team Management  Inventory Management Educational Profile: Qualification University/ institute Year of passing % (Grade) Doctor of Philosophy (Ph. D.) in Natural Product and Medicinal Chemistry CSIR-Indian Institute Of Chemical Biology and Jadavpur University, Kolkata, West Bengal, India. Thesis entitle “Synthesis of various analogues based on Andrographolide and Betulinic acid and evaluation of their anti-cancer potential” Mentor: Dr. Chinmay Chowdhury & Dr. Nakul Chandra Maiti 2015 (76.5% in course work) 1st M. Sc. (Specialization in Organic Chemistry) Vidyasagar University; Midnapore; West Bengal, India 2007 62.9 1st B. Sc (Chemistry) University of Calcutta, Kolkata, West Bengal, India 2005 52.12 2nd Personal Details:  Date of Birth: 31 st March, 1983  Sex: Male  Nationality: Indian  Marital Status: Married
  • 3. Publications: 1. A rapid and facile method for the general synthesis of 3-aryl substituted 4,5,6,7- tetrahydro[1,2,3]triazolo[1,5-a]pyrazines and their ring fused analogues; Chinmay Chowdhury, Sanjukta Mukherjee, Biswajit Chakraborty and Basudeb Achari; Organic & Biomolecular Chemistry, 2011, 9, 5856-5862. (Impact factor: 3.56) 2. Apoptotic and Autophagic Effects of Sesbania grandiflora Flowers in Human Leukemic Cells; Rajneeta Roy,Deepak Kumar, Biswajit Chakraborty, Chinmay Chowdhury, Padma Das; PLoS ONE, 2013, 8(8) e71672. (Impact factor: 3.23) 3. Synthesis and biological evaluation of andrographolide analogues as anti-cancer agent’; Ranjan Preet*, BiswajitChakraborty*, Sumit Siddharth, Purusottam Mohapatra, Dipon Das, Shakti Ranjan Satapathy, Supriya Das, Nakul C.Maiti, Prakas R. Maulik, Chanakya Nath Kundu and Chinmay Chowdhury; European Journal of Medicinal Chemistry, 2014, 85, 95−106. (* contributed equally) (Impact factor: 3.45) 4. Induction of apoptosis by a potent Betulinic acid derivative in Human colon carcinoma HT-29 cells; Debasmita Dutta, Ankita Sarkar, Biswajit Chakraborty, Chinmay Chowdhury and Padma Das; International Journal of Scientific and Research Publications, 2015, 5(2), 1-5. (Impact factor: 2.07) 5. Synthesis and biological evaluation of a novel betulinic acid derivative as inducer of apoptosis in human coloncarcinoma cells (HT- 29); Biswajit Chakraborty, Debasmita Dutta, Sanjukta Mukherjee, Supriya Das, Nakul C. Maiti,Padma Das and Chinmay Chowdhury; European Journal of Medicinal Chemistry, 2015, 102, 93-105. (Impact factor: 3.45) 6. A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomaldegradation pathway in HT-29 cells; Debasmita Dutta, Biswajit Chakraborty, Ankita Sarkar, Chinmay Chowdhury and Padma Das; BMC Cancer, 2016, 16, 23. (Impact factor: 3.36) 7. 14-deoxy-11,12-didehydroandrographolide: A Novel Compound Isolated From Andrographis Paniculata Nees. Induces Robust Apoptosis In Leukemic Cells. Swadesh Sarkar, Biswajit Chakraborty, Chinmay Chowdhury and Santanu Paul. Pharmacognosy Phcog Mag, 2019,15, S135-43. (Impact factor: 1.53) References: I hereby declare that particulars supplied by me and that all the information’s given are true to the best of my knowledge and belief. (Signature) 1) Dr. Bikash Chandra Pal Ex Scientist, Medicinal Chemistry Division CSIR-Indian Institute of Chemical Biology Jadavpur, Kolkata-700032, India E-Mail ID: drbcpal@gmail.com Phone: +91-9432266279 2) Dr. Basudeb Achari Ex Scientist, Chemistry Division CSIR-Indian Institute of Chemical Biology Jadavpur, Kolkata-700032, India E-Mail ID: achari.basudeb@gmail.com Phone: +91-9433001083 3) Dr. Chinmay Chowdhury (Ph.D. supervisor) Principal Scientist, Chemistry Division CSIR-Indian Institute of Chemical Biology Jadavpur, Kolkata-700032, India E. Mail ID: chinmay@iicb.res.in or cchinmay2@yahoo.com Phone: +91-9007685961 4. Dr. Nakul C. Maiti, (Ph.D. supervisor) Senior Scientist, Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, Jadavpur, Kolkata-700032, India. E. Mail ID: ncmaiti@iicb.res.in Phone: +91-9432013452