6. Corona Virus
Large Family of viruses
(Common Cold – MERS – SARS )
Covid 19 - nCoV (SARS-CoV-2)
A Novel CoronaVirus,new strain not previously
identified in humans
RNAVirus
Zoonotic
8. Origin of Pandemic
Hubei province,Wuhan ,China (31st Dec 2019)
The first case in India (30th Jan 2020)
WHO declared Pandemic (11th March 2020)
Total 214 countries and territories in the world are affected
(Till Date)
(11 countries have not confirmed any cases of COVID-19.
Many of these countries withoutCOVID-19 are Pacific Island countries in Oceania)
9. Pathogenesis
ACE 2 receptors are used by virus to enter
type II pneumocytes in the lung
? Neuropilin in nasal mucosa
Multiorgan Involvement
Acute ImmunogenicThrombogenic
Inflammatory Disease