A liver transplant replaces a diseased liver with a healthy donor liver. It is needed for chronic liver conditions like cirrhosis, genetic disorders, or liver damage. Candidates are evaluated by a team of specialists and undergo tests. Living donors can donate part of their healthy liver, while deceased donors provide whole livers after death. The transplant surgery implants the donor liver, and immunosuppressants prevent rejection. Risks include infection, recurrence of the original disease, and side effects of medication. India provides liver transplants at a lower cost than other countries.
Liver Transplantation is the second most common organ transplant surgery after kidney transplant. Read on to find out the procedure, outcomes and cost of undergoing liver transplant surgery in India.
Liver transplantation or hepatic transplantation is the replacement of a diseased liver with some or all of a healthy liver from another person. Liver transplantation is a viable treatment option for end-stage liver disease and acute liver failure.
Liver transplant In India by Dr. Abhideep Chaudhary, Sir Ganga Ram Hospitaldrabhideep
This presentation is related to Liver Transplant, Liver Failure, It's causes and remedy.
Here we also talk about liver transplant scenario in india and success rate of liver transplant both cadaver or living donor.
We also give a brief about the cost of liver transplant.
Dr. Abhideep Chaudhary, is liver transplant consultant/surgeon at Sir Ganga Ram Hospital, New Delhi, India.
Email : drabhideep@yahoo.com , care@drabhideep.com
Liver Transplantation is the second most common organ transplant surgery after kidney transplant. Read on to find out the procedure, outcomes and cost of undergoing liver transplant surgery in India.
Liver transplantation or hepatic transplantation is the replacement of a diseased liver with some or all of a healthy liver from another person. Liver transplantation is a viable treatment option for end-stage liver disease and acute liver failure.
Liver transplant In India by Dr. Abhideep Chaudhary, Sir Ganga Ram Hospitaldrabhideep
This presentation is related to Liver Transplant, Liver Failure, It's causes and remedy.
Here we also talk about liver transplant scenario in india and success rate of liver transplant both cadaver or living donor.
We also give a brief about the cost of liver transplant.
Dr. Abhideep Chaudhary, is liver transplant consultant/surgeon at Sir Ganga Ram Hospital, New Delhi, India.
Email : drabhideep@yahoo.com , care@drabhideep.com
Liver transplantation current status, controversies and mythsAbhishek Yadav
Details the present status, indications, techniques about liver transplantation. Also dispels some common myths surrounding liver transplantation. #liver transplantation # living donor liver transplantation #liver cirrhosis #liver failure#transplantation#live donor#drabhishekyadav.com#liversurgeon#myths#livedonorlivertransplantation#organtransplantation#alcohololiverdisease
History of liver transplant.
Why and When liver need to be transplant ?
What at basic requirements in LT.
Success and Failure %age
Global statistics of organ donation
Will someone from the family gift your child their liver?Jia Maheshwari
Never say never - never lose hope. You never know when a liver donor will be found and be a blessing for your family member suffering from end stage liver disease. But a lot of caution and care is required to guard against increasing instances of post surgery complications such as ones related to the biliary tract.
Selection and maintenance of a cadaver donor for liver transplantationApollo Hospitals
The need for the cadaver organ for liver transplant is increasing. Extended criteria/marginal donors can increase the donor pool significantly as ideal donors are very few. The combination of multiple marginal factors seems to be additive on graft injury. Although the organs from marginal donors may not be optimal, they are a viable alternative to dying while waiting for transplantation. In this review, the utility of various marginal donors in patients requiring liver transplantation will be described. It is inferred that older donors, mild to moderate steatosis, hypernatremia (preferably after correction), high ianotropic requirement, bacteremia, etc. are acceptable. Selected patients with low-grade malignancy may be accepted. Donors with positive viral serologies where transmission to the recipient is possible should be used only if the recipient is already infected with the same agent or the recipient has a critical need. The importance of liver biopsy and the goals of donor maintenance are also described. It is also concluded that the patients with high model for end-stage liver disease (MELD) score (>20) benefit the most with the marginal organs.
Scoring systems used to grade patients in liver disease , their impact on outcomes in liver transplant and perioperative setting. We describe the history of scoring systems in liver disease, their relevance to liver transplatation, critical care management and operating theater decisions.
Road to a Transplant: A glimpse at the organ transplantation processamylcarey
A brief look at the organ transplantation process. Inspired by Brian Primack, a heart transplant patient with Massachusetts General Hospital, Boston, MA. Listed with UNOS, Nov 2011.
Liver transplantation current status, controversies and mythsAbhishek Yadav
Details the present status, indications, techniques about liver transplantation. Also dispels some common myths surrounding liver transplantation. #liver transplantation # living donor liver transplantation #liver cirrhosis #liver failure#transplantation#live donor#drabhishekyadav.com#liversurgeon#myths#livedonorlivertransplantation#organtransplantation#alcohololiverdisease
History of liver transplant.
Why and When liver need to be transplant ?
What at basic requirements in LT.
Success and Failure %age
Global statistics of organ donation
Will someone from the family gift your child their liver?Jia Maheshwari
Never say never - never lose hope. You never know when a liver donor will be found and be a blessing for your family member suffering from end stage liver disease. But a lot of caution and care is required to guard against increasing instances of post surgery complications such as ones related to the biliary tract.
Selection and maintenance of a cadaver donor for liver transplantationApollo Hospitals
The need for the cadaver organ for liver transplant is increasing. Extended criteria/marginal donors can increase the donor pool significantly as ideal donors are very few. The combination of multiple marginal factors seems to be additive on graft injury. Although the organs from marginal donors may not be optimal, they are a viable alternative to dying while waiting for transplantation. In this review, the utility of various marginal donors in patients requiring liver transplantation will be described. It is inferred that older donors, mild to moderate steatosis, hypernatremia (preferably after correction), high ianotropic requirement, bacteremia, etc. are acceptable. Selected patients with low-grade malignancy may be accepted. Donors with positive viral serologies where transmission to the recipient is possible should be used only if the recipient is already infected with the same agent or the recipient has a critical need. The importance of liver biopsy and the goals of donor maintenance are also described. It is also concluded that the patients with high model for end-stage liver disease (MELD) score (>20) benefit the most with the marginal organs.
Scoring systems used to grade patients in liver disease , their impact on outcomes in liver transplant and perioperative setting. We describe the history of scoring systems in liver disease, their relevance to liver transplatation, critical care management and operating theater decisions.
Road to a Transplant: A glimpse at the organ transplantation processamylcarey
A brief look at the organ transplantation process. Inspired by Brian Primack, a heart transplant patient with Massachusetts General Hospital, Boston, MA. Listed with UNOS, Nov 2011.
Best Liver Transplantation, Liver Treatment and Liver Transplant Hospitals in Hyderabad, Bangalore, Chennai and Mumbai
Global Hospitals India’s leading Multi-Specialty, Multi-Organ Transplant Centre with locations in Hyderabad, Chennai, Bangalore and Mumbai. The hospital is home to the Institute of Liver, Pancreases Diseases and Transplants that is the foremost liver transplant facilities in the country with expertise for both live-donor and cadaver transplants.
The hospitals offers state-of-the-art infrastructure alongside a team of high-skilled doctors - with competencies to treating a wide array of liver-related ailments and emergencies.
Global Hospitals is the leading tertiary healthcare provider and has pioneered several advanced liver transplant surgeries. Acomprehensive liver disease and transplant centre - the institute has successfully performed over 600 transplants.
Comprising of some of the best known transplant surgeons, the state-of-the-art infrastructure facility delivers best post-operative care for complex hepatology cases and Hepatobiliary Surgeries, including Hepatitis C, Liver Cirrhosis, Fatty Liver Disease and others
cDR SUDHASATTWA SEN is a senior consultant and former head of the department. He also supervises Dept. Of GI HPB Surgery and GI HPB ONCO SURGERY at AMRI HOSPITAL, Dhakuria, Kolkata. Besides this, he is a JT director and Senior consultant of GI HPB and GS Department at Medica Super speciality Hospital, Kolkata (Former). Before joining the Medica family formerly; He was a senior consultant at Apollo Gleneagles, Fortis Kolkata, and Belle Vue Kolkata, CMRI, Woodlands, EEDF &SASK.
Dr. Sen’s achievements in each and every division of the medical field are commendable which made him win the award for best laparoscopic surgeon in Kolkata. He is also known as a top colorectal specialist in Kolkata. He has done a commendable job in treating acute gastrointestinal diseases and providing the best quality of services to his patients and also handles complicated gastro issues. Dr. Sen has performed many successful surgeries and has proved his mastery in the medical field by saving thousands of lives.
Liver transplant surgery is a procedure in which the defective liver of the patient is replaced by the healthy liver of another person who is also known as the donor. Rising Health Care provides the best medical services to patients searching for a top liver hospital in India.
Kidney transplantation is a life-altering procedure that provides hope and renewed vitality to individuals suffering from end-stage kidney disease. By delving into the intricacies of kidney transplantation, encompassing the procedure, types, costs, factors influencing success rates, and patient care guidelines, individuals can make well-informed choices to maximize their chances of a successful transplant and an enhanced quality of life.
At Mozocare, we understand the significance of finding the best center for kidney transplantation. We strive to empower patients by providing them with the necessary information and resources to make informed decisions. Our platform facilitates access to a network of renowned hospitals and medical professionals specializing in kidney transplantation, offering state-of-the-art facilities, experienced transplant teams, and high success rates. We aim to connect patients with the best hospitals in India, ensuring personalized care and a seamless healthcare journey.
Liver Transplant Surgeon_ The Architects of Second Chances.docxNoor Medicare
The human liver is an astonishingly resilient organ, responsible for vital functions like metabolism, detoxification, and digestion. However, when it succumbs to disease or damage, the consequences can be life-threatening. In these dire circumstances, liver transplant surgeons emerge as the architects of second chances. This document delves into the pivotal role of liver transplant surgeons.
Searching for an Organ Transplant surgeon? Dr. Ninad Deshmukh is a highly experienced Organ Transplant surgeon in Pune India with 15 years of a remarkable experience.
Similar to cost of Liver Transplant surgery in India (20)
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
2. About Liver Transplant in India
A liver transplant is a medical procedure in which a patient's diseased
liver is replaced with a whole or partial healthy liver taken from another
person. This article explains the current indications for liver
transplantation, types of liver donors, the operation itself, and the
immunosuppression that is required after liver transplantation.
Liver Transplant patients are diagnosed by an integrated
multidisciplinary team consisting of GI and Liver Transplant
Surgeons, Hepatologists, Surgical Critical Care
Specialists, Interventional Radiologists and other Supporting services
such as radiology, transfusion services, infectious diseases,
microbiology, histopathology, nephrology and dedicated ICU staff.
3. When Is a Liver Transplant Needed?
The following conditions may result in chronic liver failure:
Chronic hepatitis with cirrhosis.
Primary biliary cholangitis (it is a rare condition where the immune system
inappropriately attacks and destroys the bile ducts)
Sclerosing cholangitis (scarring and narrowing of the bile ducts inside and outside of
the liver, causing the backup of bile in the liver)
Biliary atresia (a rare disease of the liver that affects newborns)
Alcoholism
Wilson's disease (a rare inherited disease with abnormal levels of copper throughout
the body, including the liver)
Hemochromatosis (a common inherited disease where the body has too much iron)
Alpha-1 antitrypsin deficiency (an abnormal buildup of alpha-1 antitrypsin protein in
the liver, resulting in cirrhosis)
5. How are candidates for Liver Transplant
selected?
The team may include the following professionals:
Liver specialist (hepatologist)
Transplant surgeons
Transplant coordinator or usually a registered nurse who specializes in the
care of liver transplant patients
Social worker to discuss your support network of family and friends,
employment history, and financial needs
Psychiatrist to help you deal with issues, such as anxiety and depression,
which may accompany a liver transplant
Anesthesiologist to discuss potential anesthesia risks
Chemical dependency specialist to aid those with history of alcohol or drug
abuse
6. Which Tests are required before getting a
Liver Transplant?
Some or all of the following studies are generally performed during an
evaluation.
Computed tomography, or CT, which uses X-rays and a computer to create
pictures of the liver, showing its size and shape to rule out hepatocellular
carcinoma. CT scan and chest x-rays will also be taken to evaluate your heart and
lungs.
Doppler ultrasound to determine if the blood vessels to and from the liver are
open.
Echocardiogram to help check the heart function.
Pulmonary function studies to determine the lungs' ability to exchange oxygen
and carbon dioxide
Blood tests to determine blood type, clotting ability, and biochemical status of
blood, and to gauge liver function. HIV, other viral testing and hepatitis
screening are also included.
7. Where does a Liver for a Transplant Come
From?
There are two types of liver transplant options: living donor
transplant and deceased donor transplant.
Living donor:
Living donor liver transplants are an alternative for some patients
with the end-stage liver disease. This involves removing a segment
of liver from a healthy living donor and implanting it into a
recipient. Both the donor and recipient liver segments will grow to
normal size in few weeks.
8. Continue
Deceased Donor:
In deceased donor liver transplants, the donor may be a victim of
an accident or head injury. The donor's heart is still beating, but the
brain has stopped functioning. Such a person is considered legally
dead, because his or her brain has permanently and irreversibly
stopped working. At this point, the donor is usually in an intensive-
care unit and life support is withdrawn in the operating room during
the transplant.
9. Types of Liver Transplant Procedure:
Orthotopic Liver Transplantation
In Orthotopic Liver Transplantation, the recipient's diseased
liver is completely replaced with the healthy liver.
2. Heterotopic Liver Transplantation
In Heterotopic Liver Transplantation, the diseased liver is kept
remain intact at its place and donor's liver is placed at the nearest
site to the diseased liver. Heterotopic Liver Transplantation is
performed when the doctor is of the opinion that the diseased liver
might recover, if the liver recovers, the other organ shrivels away,
if not, then the original one shrivels and the donor's liver performs
the body functions.
10. Continue
3. Reduced size Liver Transplantation
Reduced Size Liver Transplantation is done on children and
involves the transplanting a part of the healthy donor liver into a
patient. Reduced Size Liver Transplantation is performed when 15-
20% of the original liver is intact. This way, one donor liver can be
used for two successful transplants.
11. What complications are associated with Liver
Transplant?
Some common problems related to liver transplant are the
following:
Rejection
Infection
Recurrent Disease
Post-Transplant Lymphoprolipherative Disorder (PTLD)
12. Best hospitals for Liver Transplant in
India?
Medanta- The Medicity, Gurgaon
Fortis Escorts, New Delhi
Apollo Hospital, Bangalore
Kokilaben Dhirubhai Ambani Hospital, Mumbai
Jaypee Hospital, Noida
BLK Hospital, Delhi
Global Hospital, Delhi
Artemis Health and Research Institute, Gurgaon
Dr. L. H. Hiranandani Hospital, Mumbai
Breach Candy Hospital, Mumbai
Lilavati Hospital, Mumbai
Sir Ganga Ram Hospital, Delhi
13. What is the cost of Liver Transplant in India?
Cost of Liver Transplant in India is:
1. Government Hospitals
The cost of liver transplant in India lies between 5 Lakhs - 10
Lakhs INR (i.e. USD 7500 - USD 16000).
2. Private Hospitals
In these hospitals the cost of liver transplant in India lies between
18 Lakhs - 24 Lakhs INR (i.e. USD 28000 - USD 40000).
14. Cost Comparison India vs Other
Countries
Cost of Liver Transplant Surgery in USA is approx to Rs. 2
crores ($300,000).
Cost of Liver Transplant Surgery in Singapore is approx to Rs.
1.2 crores ($200,000).
Cost of Liver Transplant Surgery in UK is approx to Rs. 1.2
crores ($200,000).
Cost of Liver Transplant in India is approx to Rs. 20 lakhs
($35,000).
15. Medical Tourism in India
Medical Tourism is a form of associating patients to world class
medical, dental and cosmetic surgery facilities overseas. India is a
growing destination for medical tourism, and people from all over
the world are looking to visit India for medical needs.
Medical Tourism involves traveling abroad to take world class
medical treatment at very economical rates, as compared to
countries like US, UK and Australia. As a result of which, we can
see a rise in Indian medical tourism with each of the passing day.
16. How to get medical visa to India
Lazoi is an online healthcare portal where the patients can come and book their
appointments with any of the doctors irrespective of their location. We are having
best Gastrointestinal surgeons in India who remains ready to work for the welfare
of the patients.
If you are an international patient and you had your medical treatment done in
India, you will get the facility of having second opinion with the doctor in the
mode as you like which will be provided by us. You can ask an online query, get
tele-consultation with the doctor or you can have an online video consultation.
This helps in saving the travel time of the international patients.
We act as a bridge and provide various facilities to the patients as well as the
doctors. This is because patients do not have the access of doctors. Lazoi is a
formal and a high reputed organization which is trusted by many. Beware of
misguiding agents which further can harm you and may also take huge amount of
money.
17. Contact Us
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