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This document is the curriculum vitae of Dr. William M. Coplin dated May 6, 2015. It summarizes his education, including obtaining an MD from Baylor College of Medicine in 1989. It also lists his postgraduate training and faculty appointments from 1989 to 2012 at institutions including the University of Washington and Wayne State University. Finally, it outlines his extensive professional experience and accomplishments in neurocritical care, including leadership roles in major societies.

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COPLIN_CV_05.06.2015 Updated: 6 May 2015 __________________________ Signature WILLIAM M. COPLIN, MD, FCCM, FNCS E-mail: wmcoplin@gmail.com EDUCATION Medical: Baylor College of Medicine, Houston, TX, MD May 1989 Baccalaureate: University of Chicago, IL, AB, Biological Sciences June 1985 Other: University of Alabama, Birmingham, Physics, Summer 1983 Other: Cornell University, Ithaca, NY, Biology, Summer 1980 DATES 1985-1989 1981-1985 1983 1980 POSTGRADUATE TRAINING Fellowships: University of Washington, Seattle Senior Fellow, Department of Neurological Surgery (Critical Care) Senior Fellow, Division of Pulmonary & Critical Care Medicine Residency: University of Washington, Seattle, Neurology Internship: University of Washington, Seattle, Internal Medicine 1995-1996 1994-1996 1990-1993 1989-1990 FACULTY APPOINTMENTS Associate Professor, Departments of Neurology & Neurological Surgery, Wayne State University, Detroit, MI Assistant Professor, Neurological Surgery, Wayne State University, Detroit, MI Assistant Professor, Neurology, Wayne State University, Detroit, MI Acting Instructor, Neurology/Medicine, University of Washington, Seattle 2001-2012 1996-2001 1996-2001 1993-1996 HOSPITAL OR OTHER PROFESSIONAL APPOINTMENTS Trauma Performance Improvement Patient Safety Committees, Penrose Hospital, Colorado Springs, CO Stroke Excellence Committee, Penrose-St. Francis Health Services, Colorado Springs, CO Medical Staff, Penrose Hospital, Colorado Springs, CO Medical Staff, St. Mary-Corwin Hospital, Pueblo, CO Neurocritical Care & Neurosciences Medical Director, Neurosciences System of Care, Centura Health, Englewood CO Neurosciences Council (co-chair) Centura Health, Englewood, CO Spine Council (co-chair), Centura Health, Englewood, CO Trauma Council (ad hoc), Centura Health, Englewood, CO Growth & Innovation Committee, Centura Health, Englewood, CO Clinical Improvement Steering Committee (invited guest, ad hoc), Centura Health, Englewood, CO Physician Champion, System Stroke Coordinators, Centura Health, Englewood, CO Level-One Trauma, Trauma Morbidity and Mortality, and Trauma Quality Improvement Operations Committees, St. Anthony Hospital, Lakewood, CO Pharmacy & Therapeutics Committee, St. Anthony Hospital, Lakewood, CO Critical Care Practice Council, St. Anthony Hospital, Lakewood, CO Stroke/Neuroscience Peer Review Committee, St. Anthony Hospital, Lakewood, 2014-2015 2014-2015 2014-2015 2014-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2014 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 2 CO Director, Neurocritical Care, St. Anthony Hospital, Lakewood, CO Medical Staff, St. Anthony Hospital, Lakewood, CO Comprehensive Stroke Research Committee, Penrose Hospital, Colorado Springs, CO Neurosciences Committee, Littleton Adventist Hospital, Littleton, CO Trauma Committee (ad hoc), Littleton Adventist Hospital, Littleton, CO Neurosciences Committee, Parker Adventist Hospital, Parker, CO Spine Committee, Parker Adventist Hospital, Parker, CO Trauma Committee (ad hoc), St. Mary-Corwin Hospital, Pueblo, CO TBI Committee, St. Anthony Summit Medical Center, Frisco, CO Resuscitation Committee, Detroit Medical Center hospitals, MI System-Wide Stroke Committee, Detroit Medical Center hospitals, MI System-Wide Critical Care Committee, Detroit Medical Center hospitals, MI Pharmacy and Therapeutics Committee, Detroit Medical Center hospitals, MI Chief of Neurology, Detroit Receiving Hospital, MI Medical Director, Neurotrauma & Critical Care, Detroit Receiving Hospital, MI Ethics Committee, Detroit Receiving Hospital, MI Physician Champion, Organ Donation Protocol Committee, Detroit Receiving Hospital, MI Program Director, Neurotrauma and Neurocritical Care Fellowships, Wayne State University/Detroit Medical Center, MI Level-One Trauma and Trauma Morbidity and Mortality Committees, Detroit Receiving Hospital, MI Special Care Committee, Detroit Receiving Hospital, MI Medical Staff, Detroit Receiving Hospital/Detroit Medical Center hospitals, MI 2013-2014 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2010-2012 2009-2012 2009-2012 1999-2012 1999-2011 1998-2011 1998-2012 1998-2012 1997-2011 1996-2012 1996-2012 1996-2012 MAJOR PROFESSIONAL SOCIETIES Neurocritical Care Society – Founding Board Member (inception-2013; http://www.neurocriticalcare.org/about-us/history); initial Co-Chair, Long-Range Planning Committee (past); Annual Meeting Committee (past); External Ventricular Drain Guidelines Committee (current); Co-Chair, Emergency Neurological Life Support Certification Subcommittee (current) American Neurological Association American Stroke Association/AmericanHeart Association – Stroke Council American Association of Neurological Surgeons – Executive Committee, Joint Section on Neurotrauma & Critical Care (2000-present) Congress of Neurological Surgeons – Executive Committee, Joint Section on Neurotrauma & Critical Care (2000-present) Society of Critical Care Medicine – Past Chair, Neuroscience Section (2004-2006); Program Planning Committee (2004-2009); Course Director, Neurocritical Care (2005-2009); Sedation and Analgesia PracticeParameters Committee (1998-2010) American Academy of Neurology – Past Chair, Critical Care and Emergency Neurology Section (2005-2007); Executive Committee, CriticalCare and Emergency Neurology Section (2007-2009); Course Director, Neurotrauma Course (past) 1999-present ~2000-2011 ~1997-present ~1996-present ~1996-present ~1994-present ~1990-present
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 3 MEDICAL LICENSURE Colorado DR.0053222 (11/25/2013 – 4/30/2015) Michigan 4301068197 (5/22/1996 – 1/31/2015) Washington MD00028748 (expired 2/7/97) BOARD CERTIFICATION FLEX (630207004, 12/1990) Neurology (expires 3/2018) Neurocritical Care (expires 12/2020) Advanced Cardiac Life Support Advanced Trauma Life Support – Instructor Emergency Neurological Life Support - Instructor HONORS/AWARDS Best Attending Physician (Nursing), Detroit Receiving Hospital Neurology Residents’ Teaching Award, Wayne State University Presidential Citations, Society of Critical Care Medicine School of Medicine Teaching Award, Wayne State University Joseph F. Dasta Pharmacy Research Award (with Denise H Rhoney, PharmD), Society of Critical Care Medicine Nursing Research Award, Society of Critical Care Medicine 2010-2011 2008-2009 1999, 2007 2003-2004 2003 2000 SERVICE Centura Health Neurotrauma & Neurocritical Care, Acute Stroke Team, Neurology inpatient service – on-call emergency and inpatient coverage and consultative coverage and availability St. Anthony Hospital, Penrose Hospital, St. Francis Medical Center Neurocritical Care, Neurotrauma, Acute Stroke Team, Neurology, and Neurosurgery – consultative and clinical guidance availability, case reviews Centura Health Neurosciences System of Care (15 hospitals and 9 affiliates) Centura Health Neuroscience System of Care (SOC) Accomplishments  Neuroscience SOC Redefined and updated to include all neurology, neurological surgery and some psychiatry, otolaryngology, and physical medicine & rehabilitation diagnoses  Neuroscience disease-based database constructed  Centura regained top market share for stroke and TIA  Centura Health Physician Group neuro-interventionalists joined to cross- cover multiple facilities  St. Anthony Hospital achieved Joint Commission (TJC) Comprehensive Stroke Center certification  Avista Adventist and St. Catherine’s hospitals achieved TJC Primary Stroke Center certification  Avista Adventist and St. Anthony North hospitals obtained fulltime neurology acute care coverage  Avista Adventist Hospital achieved TJC Spine Certification 2013-2015 2013-2015 2013-2015
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 4  Neuroscience-specific outreach and provider/staff education established (over 102 encounters)  Littleton Adventist Hospital (LAH) opened Centura’s first Epilepsy Monitoring Unit (EMU)  LAH performed the world’s first asleep Deep Brain Stimulation (DBS) surgery with the Mazor® Robotic Guidance System  Centura became the US’s first healthcare system to partner (with CortiCare®) in continuous EEG cloud monitoring  Two research studies with platform presentations at the International Stroke Conference; won “best of” honors for representation at American Heart Association Annual Sessions National Meeting  One abstract accepted and presented at the Society of Critical Care Medicine  National presentation at Society of Interventional Neurology Annual Meeting (Ms. Santos, System VP Neuroscience & administrative dyad partner)  System-wide standardization for swallow screen, stroke patient and family education, and stroke order sets  System-wide standardization for Triage Back Pain Protocol  System guidelines of care and order set standardization for Therapeutic Temperature Management after Cardiac Arrest, Spinal Cord Injury, Severe Traumatic Brain Injury Wayne State University Clinical Neurotrauma & Neurocritical Care inpatient services – shared duty, continual availability Detroit Receiving, Harper, Sinai-Grace, Hutzel, and Children’s hospitals Acute stroke team – shared duties for continuous coverage Detroit Receiving, Harper, Sinai-Grace, Huron Valley, and Children’s hospitals; Michigan Stroke Network Neurology inpatient service – ad hoc ward coverage Detroit Receiving Hospital Neurotrauma, Stroke, Neurocritical Care, Pulmonary & Critical Care, Trauma Surgery, and Burn Surgery fellows – supervisionand training Neurology, Neurological Surgery, Emergency Medicine, Physical Medicine & Rehabilitation residents – supervision and training Departmental/Divisional Department of Neurology Internal Review Committee Department of Neurological Surgery Internal Review Committee Fellowship Director, Neurotrauma and Neurocritical Care Fellowships School of Medicine Emergency Medicine Chair Search Committee Pediatrics Chair Search Committee 1996-2011 1997-2011 1996-2011 1996-2011 1996-2011 1997-2011 Professional (e.g., other medical or scientific organizations and societies) April 1997 - 2003 American Academy of Neurology Critical Care and Emergency Neurology Section Credentialing Committee
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 5 February 1998 - 2011 NACABI Intraventricular Thrombolysis Trial Executive Committee December 1998 – 2010 Society of Critical Care Medicine Sedation and Analgesia Practice Parameters Committee February 2000 – January 2002 Society of Critical Care Medicine Neurosciences Section, Secretary/Treasurer May 2000 – May 2008 Interventional Management of Stroke clinical trial Steering Committee Fall 2000 - Present AANS/CNS Joint Section on Neurotrauma and Critical Care Executive Committee – Critical Care and Neurocritical Care liaison Spring 2001 – Spring 2009 American Academy of Neurology Section on Emergency and Critical Care Executive Committee January 2002 – 2004 Society of Critical Care Medicine Neurosciences Section, Chair-Elect August 2002 – September 2014 Neurocritical Care Society Board of Directors, founding member January 2004 – Present Society of Critical Care Medicine Neurosciences Section, Chair January 2002 – 2004 AANS/Brain Trauma Foundation Guidelines for the Management of Severe Traumatic Brain Injury Committee November 2012 – Present Neurocritical Care Society Brain Death Subcommittee of NCS Ethics Committee January 2013 – Present Neurocritical Care Society External Ventricular Drains Guidelines Committee and co-author January 2015 – Present Neurocritical Care Society Emergency Neurological Life Support Subcommittee on Certification, Co-Chair
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 6 Community (e.g., presentations for lay audiences, educational outreach, media presentations/interviews) News service interviews: Traumatic brain injury, stroke, and hemicraniectomy, hypothermia: MSNBC et al. Michigan Stroke Initiative, Enhancing Access to Acute Stroke Care in Michigan Communities, 1999-2011 Great Lakes Transplantation Association, medicaladvisory board, 1999- 2011 Wayne County Traffic Safety Commission, 2000-2011 Community Stroke education, Detroit, MI Community Education and Feedback for Waiver of Informed Consent for Hemicraniectomy clinical trial, Detroit, MI Brain Injury Association of Michigan Brain Injury Association of Colorado, May 2014 Online Live Chat – Stroke Prevention – Centura Health, May 2013 Centura Health Neurosciences System of Care, Affiliate, Critical Accessand Community Outreach, May 2013-January 2015 (* = multiple) – includes presentations, clinical and didacticeducation, case reviews, etc Cheyenne Regional Medical Center, Cheyenne, WY Denver Health Medical Center, Denver, CO Aspen Valley Hospital, Aspen, CO St. Vincent’s Hospital, Leadville, CO* Longmont United Hospital, Longmont, CO* Platte Valley Medical Center, Brighton, CO* Good Samaritan Medical Center, Lafayette, CO Heart of The Rockies Regional Medical Center, Salida, CO* San Luis Valley Regional Medical Center, Alamosa, CO* Rio Grande Hospital, Del Norte, CO* Conejos County Hospital, La Jara, CO Pagosa Springs Medical Center, Pagosa Springs, CO* San Juan Regional Medical Center, Farmington, NM Southwest Memorial Hospital, Cortez, CO Lincoln Community Hospital, Hugo, CO Miners’ Colfax Medical Center, Raton, NM Kit Carson County Memorial Hospital, Burlington, CO Goodland Regional Medical Center, Goodland, KS Consulting Remifentanil Advisory Board, Glaxo-Wellcome, February 1998
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 7 Tirilazad Mesylate in SAH advisory panel, Pharmacia & Upjohn, April 1999 Innercool Therapies, Stroke Initiative, April 2000 Medivance Hypothermia Panel/Arctic Circle, Feb. 2002 – 2011 Integra Neurosciences, 2002 – Present Ortho-McNeil, 2003 – 2008 ESP Pharma, 2003 – 2005 PDL Biopharma, 2005-2008 UCB Pharma, 2015 – Present Bard Medical, 2015 – Present Multiple investment banking organizations Scholarly Service Grant Review Committees National June 1999 - 2005 NIH/NINDS - Member Cell Death and Injury in Neurodegeneration Study Section (formerly Brain Disorders and Clinical Neurosciences –3) NIH/NINDS: Clinical Trials Study Group – Ad hoc Regional/Local Rehabilitation Institute of Michigan internal grant reviews – last 2011 Service for Peer-Reviewed Journals Editorial Board Membership – Neurocritical Care Review of Manuscripts – ad hoc reviews for Neurosurgery, Journal of the Neurological Sciences, American Journal of Kidney Diseases, Respiratory Care, Neurology, Stroke, Archives of Neurology, Cerebrovascular Diseases, New England Journal of Medicine, Journal of Stroke and Cerebrovascular Diseases, Annals of Neurology, Journal of Neuroimaging, Critical Care, and Critical Care Medicine Moderator for numerous scientific sessions, e.g., Rocky Mountain Neurocritical Care Conference, Denver, 2013 (Course Director); Neurocritical Care Society; Society of Critical Care Medicine (Course Director, Neurocritical Care); American Academy of Neurology (Course director, Neurotrauma, 2002-
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 8 2003); International NeurocriticalCare Symposia – Panama; IInd National Workshop – Critical Care Neurology, Hyderabad, India (Course Director, Critical Care Neurology, 2003) OTHER SERVICE DATES TEACHING Centura Health Neurosciences System of Care, Centura Health Hospital Affiliates, Colorado Critical Access Hospital Outreach Undergraduate students Bedside rounding Nursing and Respiratory Therapy Medical students Bedside rounding Rocky Vista University College of Osteopathic Medicine Residents/Fellows Bedside rounding and didactic (see didactic below) St. Anthony Hospital Surgical residents University of ColoradoPulmonary & Critical Care Medicine fellows Physicians/Nurses/Pharmacists (CME/CEU/CE) Bedside/clinical rounds; didactics; case reviewsfor Neurology, Stroke/ICH/SAH, Neurosurgery, Trauma, Neuroradiology, Skull-Base Surgery/Otolaryngology/Head & Neck Surgery, and Emergency Medicine; also see Invited Lectures/Presentations Wayne State University Teaching at Wayne State University Under the categories below, list course number/title or type of teaching activity and your role. Indicate year(s) when taught. Undergraduate students Shadowing elective in Neurology/Neuro-Emergencies/Neurocritical Care/Neurotrauma for high school and Wayne State University college students Graduate students School of Pharmacy Students – regular rotation through NeuroICU Shadowing elective for Wayne State University Law School students Neuropsychology resident and fellow didactics – traumatic brain injury Certified Registered Nurse Anesthetist students Lectures - airway management and ventilation of the brain-injured Clinical Preceptorship – neuroemergencies, neurotrauma, and neurocritical care Advanced Cinical Nurse Practitioner students 2013-2015 1996-2012
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 9 Clinical Preceptorship - neuroemergencies, neurotrauma, and neurocritical care Medical students Year Two – lectures and small group didactic sessions Neuropathophysiology course Objective Structured Clinical Exam Neurology Clinical Vignettes Year Three – attending physician for Neurocritical Care/Neurology clinical rotation – included didactic core lectures Year Four – elective clinical attending and preceptorships in Neurocritical Care, Neurology, Stroke/Vascular Neurology, Neurological Surgery, Critical Care Medicine, Trauma Surgery, and Emergency Medicine – included didactic lectures Residents/Fellows Neurology Residents – rounding attending physician (NeuroICU and ward services), mentoring, didactic lectures Neurology Resident Teaching Conference Neurology Journal Club Neurology Professor’sRounds Stroke Conference Neurological Surgery Residents – rounding attending physician, (NeuroICU and ward services), mentoring, didactic lectures Neurosurgery Resident Core Lectures Neurosurgery Journal Club Neurotrauma Conference Emergency Medicine Residents – rounding attending physician (1st -year NeuroICU rotation and Senior Resident electives), mentoring, didactic lectures Pharmacy Practice Residents -- rounding attending physician (NeuroICU rotation), research mentoring, didactic lectures General Surgery Residents – rounding consulting physician, mentoring Trauma Conference Internal Medicine Residents’ board review - Neurology Physical Medicine & Rehabilitation Residents – NeuroICU elective rounding attending physician, mentoring, didactic lectures Physical Medicine & Rehabilitation Lecture Series Neurotrauma Fellows – Program Director, rounding attending physician, research mentoring, didactic lectures Neurocritical Care Fellows -- Program Director, rounding attending physician, research mentoring, didactic lectures
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 10 Pulmonary & Critical Care Medicine Fellows – rounding attending physician (scheduled Neurocritical Care rotation and electives), mentoring, didactic lectures Core Lectures Fundamentals in Critical Care Support Course – Neurologic Assessment and Support Emergency Medicine Critical Care Fellows -- rounding attending physician, mentoring, didactic lectures Trauma Surgery Fellows -- rounding attending physician(scheduled Neurotrauma/Neurocritical Care rotation and elective), mentoring, didactic lectures Burn Surgery Fellows – rounding attending physician (elective Neurocritical Care rotation), mentoring, didactic lectures Physicians/Nurses/Pharmacists (CME/CEU/CE) Didactics; case reviews for Neurology, Stroke/ICH/SAH, Neurosurgery, Trauma, Neuroradiology, and Emergency Medicine; also see Invited Lectures/Presentations Nutritionist/dietician didactics Speech and Language Therapy didactics Faculty (CME) University of Washington Graduate Professional students Law B520 (Trial Advocacy) Medical students Human Biology 550 (Basic Neurology) Medicine 686 (Neurology Clerkship) Human Biology 541 (The Respiratory System) Residents/Fellows Neurology Resident Teaching Conferences Neurology Journal Club Neurological Surgery Resident Teaching Conference Respiratory/Critical Care Conference VA Chief of Medicine Rounds VA Medicine Noon Conferences University of Washington Medicine Noon Conferences Swedish Hospital Medicine Noon Conferences Swedish Hospital Medicine Morning Report Physicians/Nurses/Pharmacists (CME/CEU/CE) Neurology, Neurological Surgery, Pulmonary & Critical Care Medicine Grand Rounds and conferences and didactics - also see Invited Lectures/Presentations Mentorship 1993-1996 1995 1993-1996 1993-1996 1995 1993-1996 1993-1996 1995
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 11 Multiple medical, pharmacy, nurse anesthetist, acute care nurse practitioner, and dietician students and residents Faith Abbott, DO, neurotrauma fellow Prasad Policherla, MD, neurotrauma and neurocritical care fellow Rodney Leacock, MD, neurotrauma and neurocritical care fellow Jacqueline Kraus, MD, neurotrauma and neurocritical care fellow Gregory Norris, MD, neurotrauma and neurocritical care fellow Ahmed Abdulsalam, MD, neurocritical care fellow Benjamin Atkinson, MD, neurotrauma and neurocritical care fellow Theses/Dissertations mentoring assistance – Wayne State University Bill D. Underwood, MD, PhD, clinical and editorial, heat shock protein and other gene expression after penetrating traumatic braininjury Julie G. Pilitsis, MD, PhD, clinical and editorial, central nervous system free fatty acid metabolism and disposition after acute brain injury John J. Steele III, MD, PhD, clinical and editorial, electrophysiological alterationsand topography after acute brain injury Course and curriculum development  Refining Skills in Nutrition Support (Educational Planning Committee) 1999  Critical Care Neurology (IInd National Workshop – Critical Care Neurology, Hyderabad, India) 2003  Neurotrauma (American Academy of Neurology) 2002 & 2003  Neurocritical Care (Society of Critical Care Medicine) 2005-2009  Neurocritical Care in Catastrophic Conditions (Neurocritical Care Society) 2011  Rocky Mountain Neurocritical Care Conference (Centura Health) 2013 1995-1996 1993-1995 1993-1995 1993-1995 1993-1994 1993-1994 1993-1996 1996-2011 GRANTS, CONTRACTS, AND OTHER FUNDING Active and Pending Grants and Contracts None Previously funded NIH Grant as PI NIH/NINDS 1 RO1 NS38905-01, Early hemicraniectomy to manage traumatic brain injury. 7/16/99 – 6/30/03, $260,606 Previously submitted, not funded Grants and Contracts as PI NIH/NINDS 1 R21 NS048744-01, IntraCranial PressurePrevention and Control Investigation. (Coplin) 1999-2003 CLINICAL TRIALS ACTIVITIES Within last two years: • A Non-Transfer Protocol for Patientswith Stable, Mild, Isolated Traumatic Brain Injury at Level III and IV Trauma Centers, co-PI • Neurotelemetry: Remote cEEG Monitoring and Reading for Neurocritical Care Patient Management, co-PI and abstract presenter • Boehringer-Ingelheim 1160.189 (ESUS study), local PI – while at Centura Health • POINT, co-investigator – while at Centura Health • Association Between Pharmacological Thromboprophylaxis And Hemorrhage Progression In
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 12 Patients With Hemorrhagic Stroke, co-investigator, abstract presenter, and lead author for manuscript in progress • Pharmacological Thromboprophylaxis Reducesthe Odds of Venous Thromboembolism In Patients With Hemorrhagic Stroke, co-investigator, abstract presenter, and lead author for manuscript in progress PUBLICATIONS • Recent and representative publications in journals(selected from > 69). Does not include presentations, abstracts, book chapters, or articles ‘in preparation’ or ‘submitted.’ Chesnut, R, et al. A Consensus-based Guide to the Interpretation of the BEST TRIP ICP Trial. J Neurotrauma. 2015;in press Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, et al. Very early administration of progesterone for acute traumatic brain injury. N Engl J Med. 2014;371(26):2457- 66. Frank JI, Schumm LP, Wroblewski K, Chyatte D, Rosengart AJ, Kordeck C, et al. Hemicraniectomy and durotomy upon deterioration from infarction-related swelling trial: randomized pilot clinical trial. Stroke. 2014;45(3):781-7. Levy AS, Salottolo K, Coplin WM, Smith R, Santos P, Bar-Or D. Pharmocologic thromboprophylaxis reduces the odds of venous thromboembolism in patients with hemorrhagic stroke. Stroke. 2014 – presented at 2014 International Stroke Conference, San Diego Levy AS, Salottolo K, Coplin WM, Orlando A, Smith R, Santos P, Bar-Or D. Association between pharmacologic thromboprophylaxis and hemorrhage progression in patients with hemorrhagic stroke. Stroke. 2014 – presented at 2014 International Stroke Conference, San Diego Coplin WM. Traumatic spinal cord injury. In: NCS Practice Update Textbook, Neurocritical Care Society, 2014. Liu-DeRyke X, Levy PD, Parker D Jr, Coplin W, Rhoney DH. A prospective evaluation of labetalol versus nicardipine for blood pressure management in patients with acute stroke. Neurocrit Care. 2013;19:41-7. Bhattacharya P, Kansara A, Chaturvedi S, Coplin W. What drives the increasing utilisation of hemicraniectomy in acute ischaemic stroke? J Neurol Neurosurg Psychiatry. 2013; 84(7):727-31. Nagaraja N, Bhattacharya P, Norris G, Coplin W, Narayanan S, Xavier A, et al. Arrival by ambulance is associated with acute stroke intervention in young adults. J Neurol Sci. 2012;316(1- 2):168-9. Coplin WM. Critical care management of acute ischemic stroke. Neurology. Continuum (Minneap Minn). 2012;18(3):547-59. Naff N, Williams MA, Keyl PM, Tuhrim S, Bullock MR, Mayer SA, et al. Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke. 2011;42(11):3009-16. Kullar R, Chin JN, Edwards DJ, Parker D, Coplin WM, Rybak MJ. Pharmacokinetics of single-dose
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 13 daptomycin in patients with suspected or confirmed neurological infections. Antimicrob Agents Chemother. 2011;55(7):3505-9. Rhoney DH, Coplin WM, Lin Y, Frankel M, Lyden PD, Levine SR. Time of day, outcome, and response to thrombolytic therapy: the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trial experience. J Stroke Cerebrovasc Dis. 2010;19(1):40-8. Browning L, Parker D, Jr., Liu-DeRyke X, Shah A, Coplin WM, Rhoney DH. Possible removal of topiramate by continuous renal replacement therapy. J Neurol Sci. 2010;288(1-2):186-9. Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, et al. Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke. 2008;39(6):1759-65. Ramappa P, Thatai D, Coplin W, Gellman S, Carhuapoma JR, Quah R, et al. Cardiac troponin-I: a predictor of prognosis in subarachnoid hemorrhage. Neurocrit Care. 2008;8(3):398-403. Liu-Deryke X, Janisse J, Coplin WM, Parker D, Jr., Norris G, Rhoney DH. A comparison of nicardipine and labetalol for acute hypertension management following stroke. Neurocrit Care. 2008;9(2):167-76. Chang CW, Torbey MT, Diringer MN, Coplin W, Mayer SA, Hemphill EC, et al. Neurointensivists: part of the problem or part of the solution? Crit Care Med. 2008;36(10):2963-4; author reply 5. Benson RR, Meda SA, Vasudevan S, Kou Z, Govindarajan KA, Hanks RA, et al. Global white matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury. J Neurotrauma. 2007;24(3):446-59. Murugappan A, Coplin WM, Al-Sadat AN, McAllen KJ, Schwamm LH, Wechsler LR, et al. Thrombolytic therapy of acute ischemic stroke during pregnancy. Neurology. 2006;66(5):768-70. Mayer SA, Coplin WM, Chang C, Suarez J, Gress D, Diringer MN, et al. Core curriculum and competencies for advanced training in neurological intensive care: United Council for Neurologic Subspecialties guidelines. Neurocrit Care. 2006;5(2):159-65. Mayer SA, Coplin WM, Chang C, Suarez J, Gress D, Diringer MN, et al. Program requirements for fellowship training in neurological intensive care: United Council for Neurologic Subspecialties guidelines. Neurocrit Care. 2006;5(2):166-71. Esper DH, Coplin WM, Carhuapoma JR. Energy expenditure in patients with nontraumatic intracranial hemorrhage. JPEN J Parenter Enteral Nutr. 2006;30(2):71-5. Borsody M, Burke A, Coplin W, Miller-Lotan R, Levy A. Haptoglobin and the development of cerebral artery vasospasm after subarachnoid hemorrhage. Neurology. 2006;66(5):634-40. Albers GW, Thijs VN, Wechsler L, Kemp S, Schlaug G, Skalabrin E, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol. 2006;60(5):508-17.
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 14 Barrett RJ, Hussain R, Coplin WM, Berry S, Keyl PM, Hanley DF, et al. Frameless stereotactic aspiration and thrombolysis of spontaneous intracerebral hemorrhage. Neurocrit Care. 2005;3(3):237-45. Larive LL, Rhoney DH, Parker D, Jr., Coplin WM, Carhuapoma JR. Introducing hypertonic saline for cerebral edema: an academic center experience. Neurocrit Care. 2004;1(4):435-40. Rhoney DH, Tam VH, Parker D, Jr., McKinnon PS, Coplin WM. Disposition of cefepime in the central nervous system of patients with external ventricular drains. Pharmacotherapy. 2003;23(3):310-4. Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Free fatty acids in cerebrospinal fluids from patients with traumatic brain injury. Neurosci Lett. 2003;349(2):136-8. Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Measurement of free fatty acids in cerebrospinal fluid from patients with hemorrhagic and ischemic stroke. Brain Res. 2003;985(2):198-201. Carhuapoma JR, Gupta K, Coplin WM, Muddassir SM, Meratee MM. Treatment of refractory fever in the neurosciences critical care unit using a novel, water-circulating cooling device. A single-center pilot experience. J Neurosurg Anesthesiol. 2003;15(4):313-8. Rhoney DH, Parker D, Jr., Formea CM, Yap C, Coplin WM. Tolerability of bolus versus continuous gastric feeding in brain-injured patients. Neurological Res. 2002;24(6):613-20. Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Free fatty acids in human cerebrospinal fluid following subarachnoid hemorrhage and their potential role in vasospasm: a preliminary observation. J Neurosurg. 2002;97(2):272-9. Narayan RK, Michel ME, Ansell B, Baethmann A, Biegon A, Bracken MB, et al. Clinical trials in head injury. J Neurotrauma. 2002;19(5):503-57. Kraus JJ, Metzler MD, Coplin WM. Critical care issues in stroke and subarachnoid hemorrhage. Neurol Res. 2002;24 Suppl 1:S47-57. Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med. 2002;30(1):119-41. Coplin WM, Rhoney DH, Rebuck JA, Clements EA, Cochran MS, O'Neil BJ. Randomized evaluation of adverse events and length-of-stay with routine emergency department use of phenytoin or fosphenytoin. Neurol Res. 2002;24(8):842-8. Tirschwell DL, Coplin WM, Becker KJ, Vogelzang P, Eskridge J, Haynor D, et al. Intra-arterial urokinase for acute ischemic stroke: factors associated with complications. Neurology. 2001;57(6):1100-3. Pilitsis JG, Diaz FG, Wellwood JM, O’Regan MH, Fairfax MR, Phillis JW, et al. Quantification of free fatty acids in human cerebrospinal fluid. Neurochem Res. 2001;26(12):1265-70. Joshi N, Chaturvedi S, Coplin WM. Poor prognosis of acute stroke patients denied thrombolysis
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 15 due to early CT findings. J Neuroimaging. 2001;11(1):40-3. Coplin WM, Cullen NK, Policherla PN, Vinas FC, Wilseck JM, Zafonte RD, et al. Safety and feasibility of craniectomy with duraplasty as the initial surgical intervention for severe traumatic brain injury. J Trauma. 2001;50(6):1050-9. Coplin WM, Cochran MS, Levine SR, Crawford SW. Stroke after bone marrow transplantation: frequency, aetiology and outcome. Brain. 2001;124(Pt 5):1043-51. Coplin WM, Broderick J, Tomsick TT. Intraarterial recombinant tissue plasminogen activator for ischemic stroke: an accelerated dosing regimen. Neurosurgery. 2001;49(1):228-9. Coplin WM. Intracranial pressure and surgical decompression for traumatic brain injury: biological rationale and protocol for a randomized clinical trial. Neurol Res. 2001;23(2-3):277-90. Vinas FC, Kazmierczak C, Coplin WM. Active intracerebral hemorrhage from the lateral posterior choroidal artery. Arch Neurol. 2000;57(6):889-90. Tipps LB, Coplin WM, Murry KR, Rhoney DH. Safety and feasibility of continuous infusion of remifentanil in the neurosurgical intensive care unit. Neurosurgery. 2000;46(3):596-601; discussion - 2. Rhoney DH, Tipps LB, Murry KR, Basham MC, Michael DB, Coplin WM. Anticonvulsant prophylaxis and timing of seizures after aneurysmal subarachnoid hemorrhage. Neurology. 2000;55(2):258-65. Rebuck JA, Murry KR, Rhoney DH, Michael DB, Coplin WM. Infection related to intracranial pressure monitors in adults: analysis of risk factors and antibiotic prophylaxis. J Neurol Neurosurg Psychiatry. 2000;69(3):381-4. Devlin JW, Coplin WM, Murry KR, Rengachary SS, Wilson RF. Nimodipine-induced acute hypoxemia: case report. Neurosurgery. 2000;47(5):1243-6; discussion 6-7. Coplin WM, Pierson DJ, Cooley KD, Newell DW, Rubenfeld GD. Implications of extubation delay in brain-injured patients meeting standard weaning criteria. Am J Respir Crit Care Med. 2000;161(5):1530-6. PRESENTATIONS International/national, local/regional, and invited Seminars and Grand Rounds since May 2013 1. Online Live Chat – Stroke Prevention – Centura Health – 5/23/13 2. Stroke in the Emergency Department: What to do… - St. Catherine Hospital (med staff) – 5/29-13 3. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – University of Virginia Neurology Grand Rounds – 5/31/13 4. Optimal Glucose Control in Hemorrhagic Stroke – St. Anthony Hospital (MD/RN) – 6/13/13 5. TBI Case Studies – St. Anthony Neuro/Trauma Nursing Staff – monthly x 2, first 6/14/13 6. Brain Injury Management – Grand Rounds Santo Tomas Hospital, Panama – 6/19/13
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 16 7. Delayed Brain Injury - 3rd International Neurocritical Care Symposium, Panama – 6/20/13 8. Updates in Neuromonitoring of TBI Patients - 3rd International Neurocritical Care Symposium, Panama – 6/20/13 9. Brain Tissue Oxygen Based Therapy and Outcome after Severe Traumatic Brain Injury - 3rd International Neurocritical Care Symposium, Panama – 6/21/13 10. Update in the Management of Traumatic Spinal Cord Injury - 3rd International Neurocritical Care Symposium, Panama – 6/21/13 11. Traumatic Spinal Cord Injury – St. Anthony Trauma Multidisciplinary QI – 7/1/13 12. Early Goal Directed Therapy for Traumatic Brain Injury – Cheyenne Regional Medical Center (WY) – 7/9/13 13. Hospital Neurological Assessments – Penrose Hospital (Centura Stroke Coordinators’ monthly meeting) – 7/12/13 14. Traumatic Spinal Cord Injury – Panorama Orthopedics (physician/PA staff) – 7/15/13 15. Controversies in Spine Injury – Parker Adventist Hospital (Spine Committee) – 7/30/13 16. Clearing the Spine in the ED: Exam, Imaging, Gear Removal, and Transition to Further Care: The Neuro Doc's Perspective – 1st Annual Rocky Mountain Sports Medicine Symposium, Durango – 8/2/13 17. Hypoxia Unplugged: Altitude and Carbon Monoxide– 1st Annual Rocky Mountain Sports Medicine Symposium, Durango – 8/3/13 18. Neurological Assessment – St. Anthony North (nursing) – 8/7/13 19. You Won’t Get Far If You Keep On Sticking Your Hand In The Medicine Jar: Steroids Work, Don’t They? – Littleton Adventist Hospital (trauma) – 8/15/13 20. Transfusion “Requirements” in Traumatic Brain Injury – Littleton Adventist Hospital (trauma) – 8/15/13 21. Toxic Encephalopathies: Ethanol Withdrawal – Critical Care Karma, Porter Adventist Hospital – 8/21/13 22. Blood Pressure Management for Different Types of Stroke - St. Anthony Hospital – 8/26/13 23. Severe Traumatic Brain Injury: Initial Assessment and Resuscitation – St. Anthony Hospital – 8/29/13 24. Use of Clinical Examination Scales in Patients with Neurological Injury: Why All the Confusion? – St. Anthony Hospital (Neurocritical Care board review series) – 9/9/13 25. Monitoreo Multimodal en Neurointensivo - Asociación Colombiana de Medicina Interna – Pasto – 9/13/13 26. Presión Tisular de Oxígeno Cerebral - Asociación Colombiana de Medicina Interna – Pasto – 9/13/13 27. Minimizing Perioperative Spine Surgery Infections: Why All The Confusion? – Parker Adventist Hospital (Spine Committee) – 9/17/13 28. Traumatic Spinal Cord Injury – Neurocritical Care Society – Philadelphia – 10/2/13 29. General Approach to Ventilating the Comatose Trauma Patient – St. Anthony Hospital (trauma) – 10/7/13 30. Fluids, Electrolytes, Resuscitation Do’s and Don’ts – St. Anthony Hospital (Neurocritical Care board review series) – 10/10/13 31. Hypercalcemia – Heart of the Rockies Regional Medical Center, Salida – 10/10/13 32. Coagulopathies – Littleton Adventist Hospital (trauma) – 10/17/13 33. Acute Management of Neurological Emergencies – St. Mary-Corwin (nursing) – 10/19/13 34. Neuropharmacology – Rocky Mountain Neurocritical Care Conference – 10/29/13 35. Neuroendocrinology – Rocky Mountain Neurocritical Care Conference – 10/30/13 36. Spinal Cord Injury – Rocky Mountain Neurocritical Care Conference – 10/30/13 37. Natural, Supernatural, and Man-Made Catastrophes – Rocky Mountain Neurocritical Care Conference – 10/30/13
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 17 38. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – St. Mary’s Medical Center’s 4th Annual Neuroscience Symposium – Advancements in Neuroscience, Palm Beach Gardens, FL – 11/2/13 39. Traumatic Intracranial Hemorrhage – Mercy Regional Medical Center Trauma Conference – 11/9/13 40. Traumatic Intracranial Hemorrhage – Mercy Regional Medical Center – 11/11/13 41. Toxic Encephalopathies: Ethanol Withdrawal – Mercy Regional Medical Center – 11/11/13 42. Mild TBI Transfer Algorithm – Mercy Regional Medical Center – 11/13/13 43. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – Critical Care Karma - 11/18/13 44. Severe TBI – St. Anthony Hospital (Neurocritical Care board review series) – 11/26/13 45. Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The Confusion? – St. Vincent Hospital, Leadville – 12/2/13 46. Multimodality Monitoring in Neurocritical Care – St. Anthony Hospital (Neurocritical Care board review series) – 12/5/13 47. Spinal Cord Injury – St. Anthony Hospital (nursing) – 12/6/13 48. There Will Be Blood – Aspen Valley Hospital (trauma) – 12/10/13 49. Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The Confusion? – Mercy Regional Medical Center – 12/11/13 50. “Neuroradiology”. Lecture for RNs. St. Anthony Hospital - 2/20/14 51. “HACA: 33 vs 36C”. CCPSA Journal Club. St. Anthony Hospital - 2/24/14 52. “Traumatic Brain Injury”. Wilz Neuroscience and Trauma Symposium. Pueblo Convention Center - 3/1/14 53. “Appropriate TBI Admissions and TBI Management, Including Rehab and Follow Up”. San Luis Valley Regional Medical Center - 3/17/14 54. “Fluid and Electrolyte Management In Critically-Ill Patients After Neurological Catastrophes”. Neurotrauma Critical Care Review and Update for Practicing Neurosurgeon. 82nd American Association of Neurological Surgeons Annual Scientific Meeting, San Francisco - 4/5/14 55. “Traumatic Brain Injury”. Miners’ Colfax Medical Center. Raton, NM - 4/10/14 56. “Telestroke” St. Thomas More Emergency Department. Canon City, CO - 4/16/14 57. “Alcohol Withdrawal Syndrome: A New Approach To Prevention and Intervention of Severe Alcohol Withdrawal Symptoms”. Mercy Regional Medical Center. Durango, CO - 4/17/14 58. “Alcohol Withdrawal Syndrome: Interdepartmental/Interdisciplinary Approach Based on the Evidence Based Medicine Review”. Mercy Regional Medical Center. Durango, CO - 4/17/14 59. “Alcohol Withdrawal Syndrome: Protocol/Standardization of Treatment in Inpatients, Pre- ICU, ICU, and ED Patients”. Mercy Regional Medical Center. Durango, CO - 4/17/14 60. “Traumatic Brain Injury”. Platte Valley Medical Center - 4/24/14 61. “Therapeutic Temperature Management after Neurological Catastrophe: Why All the Confusion?”. Trauma Multidisciplinary Meeting. St. Anthony Hospital - 5/5/14 62. “Hospital Neurological Stroke Assessments”. Mega Nursing Grand Rounds. Porter Adventist Hospital - 5/6/14 63. “Disability”. Rural Trauma Team Development Course. San Luis Valley Regional Medical Center - 5/8/14 64. “Zombie Neurobiology: Are We Ready For The Looming Apocalypse?” South State EMS. Penrose Hospital. Colorado Springs, CO - 5/13/14 65. “Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The Confusion?” Pagosa Springs Medical Center - 5/15/14 66. “Mild Brain Injury – When to Refer; When and Where to Manage”. Brain Injury Alliance of
___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 18 Colorado Summit County Conference. Beaver Run, CO - 5/16/14 67. “VTE Prophylaxis Timing after Brain and/or Spinal Cord Injury”. Penrose-St. Francis Trauma Education. Colorado Springs, CO – 9/5/14 68. “Traumatic Spinal Cord Injury”. Neurocritical Care Society. Seattle, WA – 9/10/14 69. “Guidelines are great for neurocritical care in general, but not for real experts like me.” Neurocritical Care Society. Seattle, WA – 9/14/14 70. “Concussion”. Copper Mountain Emergency Medicine. Edwards, CO – 10/23/14 71. “Head Injury and Hollywood: A Case Study of the Three Stooges”. Mercy Regional Medical Center Trauma Conference. Durango, CO – 10/25/14 72. “Urgent Warfarin Reversal”. Association of California Nurses. Santa Ana, CA – 10/28/14 73. “Association Between Pharmacological Thromboprophylaxis and Hemorrhage Progression in Patients with Hemorrhagic Stroke”. St. Mary’s Medical Center’s 5th Annual Neuroscience Symposium – A Lustrum of Progress. Palm Beach Gardens, FL – 11/1/14 74. “Association Between Pharmacologic Thromboprophylaxis and Hemorrhage Progression in Patients With Hemorrhagic Stroke”. Best of AHA Specialty Conferences at Scientific Sessions. Chicago, IL – 11/17/14 75. “Concussion and Clearing the Spine in the ED: Exam, Imaging, Gear Removal, and Transition to Further Care”. Rio Grande Hospital Quarterly Trauma Review and CME. Del Norte, CO – 11/21/14 76. “Current Trends In Neurotrauma”. Wilz Trauma Symposium. Pueblo, CO – 3/7/15 77. “Zombie Neurobiology: Are We Ready For The Looming Apocalypse?”. 12th Annual Critical Care Symposium. Manchester, UK – 4/23/15 78. “Pharmacological Thromboprophylaxis, Venous Thromboembolism & Hemorrhage Progression In Patients With Hemorrhagic Stroke: Why All The Confusion? 12th Annual Critical Care Symposium. Manchester, UK – 4/24/15 79. “Neurocritical Care Update” 12th Annual Critical Care Symposium. Manchester, UK – 4/24/15 80. “Extubation Readiness Independent Of Level Of Consciousness”. 12th Annual Critical Care Symposium. Manchester, UK – 4/24/15 81. “Coagulopathy and VTE: Timing of Use of Chemical Prophylaxis & Management of VTE Events in the Perioperative Period”. Neurotrauma Critical Care Review and Update. 83rd American Association of Neurological Surgeons Annual Scientific Meeting. Washington, DC – 5/2/15

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Coplin_CV_05.06.2015_no personal info

  • 1.
    COPLIN_CV_05.06.2015 Updated: 6 May2015 __________________________ Signature WILLIAM M. COPLIN, MD, FCCM, FNCS E-mail: wmcoplin@gmail.com EDUCATION Medical: Baylor College of Medicine, Houston, TX, MD May 1989 Baccalaureate: University of Chicago, IL, AB, Biological Sciences June 1985 Other: University of Alabama, Birmingham, Physics, Summer 1983 Other: Cornell University, Ithaca, NY, Biology, Summer 1980 DATES 1985-1989 1981-1985 1983 1980 POSTGRADUATE TRAINING Fellowships: University of Washington, Seattle Senior Fellow, Department of Neurological Surgery (Critical Care) Senior Fellow, Division of Pulmonary & Critical Care Medicine Residency: University of Washington, Seattle, Neurology Internship: University of Washington, Seattle, Internal Medicine 1995-1996 1994-1996 1990-1993 1989-1990 FACULTY APPOINTMENTS Associate Professor, Departments of Neurology & Neurological Surgery, Wayne State University, Detroit, MI Assistant Professor, Neurological Surgery, Wayne State University, Detroit, MI Assistant Professor, Neurology, Wayne State University, Detroit, MI Acting Instructor, Neurology/Medicine, University of Washington, Seattle 2001-2012 1996-2001 1996-2001 1993-1996 HOSPITAL OR OTHER PROFESSIONAL APPOINTMENTS Trauma Performance Improvement Patient Safety Committees, Penrose Hospital, Colorado Springs, CO Stroke Excellence Committee, Penrose-St. Francis Health Services, Colorado Springs, CO Medical Staff, Penrose Hospital, Colorado Springs, CO Medical Staff, St. Mary-Corwin Hospital, Pueblo, CO Neurocritical Care & Neurosciences Medical Director, Neurosciences System of Care, Centura Health, Englewood CO Neurosciences Council (co-chair) Centura Health, Englewood, CO Spine Council (co-chair), Centura Health, Englewood, CO Trauma Council (ad hoc), Centura Health, Englewood, CO Growth & Innovation Committee, Centura Health, Englewood, CO Clinical Improvement Steering Committee (invited guest, ad hoc), Centura Health, Englewood, CO Physician Champion, System Stroke Coordinators, Centura Health, Englewood, CO Level-One Trauma, Trauma Morbidity and Mortality, and Trauma Quality Improvement Operations Committees, St. Anthony Hospital, Lakewood, CO Pharmacy & Therapeutics Committee, St. Anthony Hospital, Lakewood, CO Critical Care Practice Council, St. Anthony Hospital, Lakewood, CO Stroke/Neuroscience Peer Review Committee, St. Anthony Hospital, Lakewood, 2014-2015 2014-2015 2014-2015 2014-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2014 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015
  • 2.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 2 CO Director, Neurocritical Care,St. Anthony Hospital, Lakewood, CO Medical Staff, St. Anthony Hospital, Lakewood, CO Comprehensive Stroke Research Committee, Penrose Hospital, Colorado Springs, CO Neurosciences Committee, Littleton Adventist Hospital, Littleton, CO Trauma Committee (ad hoc), Littleton Adventist Hospital, Littleton, CO Neurosciences Committee, Parker Adventist Hospital, Parker, CO Spine Committee, Parker Adventist Hospital, Parker, CO Trauma Committee (ad hoc), St. Mary-Corwin Hospital, Pueblo, CO TBI Committee, St. Anthony Summit Medical Center, Frisco, CO Resuscitation Committee, Detroit Medical Center hospitals, MI System-Wide Stroke Committee, Detroit Medical Center hospitals, MI System-Wide Critical Care Committee, Detroit Medical Center hospitals, MI Pharmacy and Therapeutics Committee, Detroit Medical Center hospitals, MI Chief of Neurology, Detroit Receiving Hospital, MI Medical Director, Neurotrauma & Critical Care, Detroit Receiving Hospital, MI Ethics Committee, Detroit Receiving Hospital, MI Physician Champion, Organ Donation Protocol Committee, Detroit Receiving Hospital, MI Program Director, Neurotrauma and Neurocritical Care Fellowships, Wayne State University/Detroit Medical Center, MI Level-One Trauma and Trauma Morbidity and Mortality Committees, Detroit Receiving Hospital, MI Special Care Committee, Detroit Receiving Hospital, MI Medical Staff, Detroit Receiving Hospital/Detroit Medical Center hospitals, MI 2013-2014 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2013-2015 2010-2012 2009-2012 2009-2012 1999-2012 1999-2011 1998-2011 1998-2012 1998-2012 1997-2011 1996-2012 1996-2012 1996-2012 MAJOR PROFESSIONAL SOCIETIES Neurocritical Care Society – Founding Board Member (inception-2013; http://www.neurocriticalcare.org/about-us/history); initial Co-Chair, Long-Range Planning Committee (past); Annual Meeting Committee (past); External Ventricular Drain Guidelines Committee (current); Co-Chair, Emergency Neurological Life Support Certification Subcommittee (current) American Neurological Association American Stroke Association/AmericanHeart Association – Stroke Council American Association of Neurological Surgeons – Executive Committee, Joint Section on Neurotrauma & Critical Care (2000-present) Congress of Neurological Surgeons – Executive Committee, Joint Section on Neurotrauma & Critical Care (2000-present) Society of Critical Care Medicine – Past Chair, Neuroscience Section (2004-2006); Program Planning Committee (2004-2009); Course Director, Neurocritical Care (2005-2009); Sedation and Analgesia PracticeParameters Committee (1998-2010) American Academy of Neurology – Past Chair, Critical Care and Emergency Neurology Section (2005-2007); Executive Committee, CriticalCare and Emergency Neurology Section (2007-2009); Course Director, Neurotrauma Course (past) 1999-present ~2000-2011 ~1997-present ~1996-present ~1996-present ~1994-present ~1990-present
  • 3.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 3 MEDICAL LICENSURE Colorado DR.0053222(11/25/2013 – 4/30/2015) Michigan 4301068197 (5/22/1996 – 1/31/2015) Washington MD00028748 (expired 2/7/97) BOARD CERTIFICATION FLEX (630207004, 12/1990) Neurology (expires 3/2018) Neurocritical Care (expires 12/2020) Advanced Cardiac Life Support Advanced Trauma Life Support – Instructor Emergency Neurological Life Support - Instructor HONORS/AWARDS Best Attending Physician (Nursing), Detroit Receiving Hospital Neurology Residents’ Teaching Award, Wayne State University Presidential Citations, Society of Critical Care Medicine School of Medicine Teaching Award, Wayne State University Joseph F. Dasta Pharmacy Research Award (with Denise H Rhoney, PharmD), Society of Critical Care Medicine Nursing Research Award, Society of Critical Care Medicine 2010-2011 2008-2009 1999, 2007 2003-2004 2003 2000 SERVICE Centura Health Neurotrauma & Neurocritical Care, Acute Stroke Team, Neurology inpatient service – on-call emergency and inpatient coverage and consultative coverage and availability St. Anthony Hospital, Penrose Hospital, St. Francis Medical Center Neurocritical Care, Neurotrauma, Acute Stroke Team, Neurology, and Neurosurgery – consultative and clinical guidance availability, case reviews Centura Health Neurosciences System of Care (15 hospitals and 9 affiliates) Centura Health Neuroscience System of Care (SOC) Accomplishments  Neuroscience SOC Redefined and updated to include all neurology, neurological surgery and some psychiatry, otolaryngology, and physical medicine & rehabilitation diagnoses  Neuroscience disease-based database constructed  Centura regained top market share for stroke and TIA  Centura Health Physician Group neuro-interventionalists joined to cross- cover multiple facilities  St. Anthony Hospital achieved Joint Commission (TJC) Comprehensive Stroke Center certification  Avista Adventist and St. Catherine’s hospitals achieved TJC Primary Stroke Center certification  Avista Adventist and St. Anthony North hospitals obtained fulltime neurology acute care coverage  Avista Adventist Hospital achieved TJC Spine Certification 2013-2015 2013-2015 2013-2015
  • 4.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 4  Neuroscience-specific outreachand provider/staff education established (over 102 encounters)  Littleton Adventist Hospital (LAH) opened Centura’s first Epilepsy Monitoring Unit (EMU)  LAH performed the world’s first asleep Deep Brain Stimulation (DBS) surgery with the Mazor® Robotic Guidance System  Centura became the US’s first healthcare system to partner (with CortiCare®) in continuous EEG cloud monitoring  Two research studies with platform presentations at the International Stroke Conference; won “best of” honors for representation at American Heart Association Annual Sessions National Meeting  One abstract accepted and presented at the Society of Critical Care Medicine  National presentation at Society of Interventional Neurology Annual Meeting (Ms. Santos, System VP Neuroscience & administrative dyad partner)  System-wide standardization for swallow screen, stroke patient and family education, and stroke order sets  System-wide standardization for Triage Back Pain Protocol  System guidelines of care and order set standardization for Therapeutic Temperature Management after Cardiac Arrest, Spinal Cord Injury, Severe Traumatic Brain Injury Wayne State University Clinical Neurotrauma & Neurocritical Care inpatient services – shared duty, continual availability Detroit Receiving, Harper, Sinai-Grace, Hutzel, and Children’s hospitals Acute stroke team – shared duties for continuous coverage Detroit Receiving, Harper, Sinai-Grace, Huron Valley, and Children’s hospitals; Michigan Stroke Network Neurology inpatient service – ad hoc ward coverage Detroit Receiving Hospital Neurotrauma, Stroke, Neurocritical Care, Pulmonary & Critical Care, Trauma Surgery, and Burn Surgery fellows – supervisionand training Neurology, Neurological Surgery, Emergency Medicine, Physical Medicine & Rehabilitation residents – supervision and training Departmental/Divisional Department of Neurology Internal Review Committee Department of Neurological Surgery Internal Review Committee Fellowship Director, Neurotrauma and Neurocritical Care Fellowships School of Medicine Emergency Medicine Chair Search Committee Pediatrics Chair Search Committee 1996-2011 1997-2011 1996-2011 1996-2011 1996-2011 1997-2011 Professional (e.g., other medical or scientific organizations and societies) April 1997 - 2003 American Academy of Neurology Critical Care and Emergency Neurology Section Credentialing Committee
  • 5.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 5 February 1998 -2011 NACABI Intraventricular Thrombolysis Trial Executive Committee December 1998 – 2010 Society of Critical Care Medicine Sedation and Analgesia Practice Parameters Committee February 2000 – January 2002 Society of Critical Care Medicine Neurosciences Section, Secretary/Treasurer May 2000 – May 2008 Interventional Management of Stroke clinical trial Steering Committee Fall 2000 - Present AANS/CNS Joint Section on Neurotrauma and Critical Care Executive Committee – Critical Care and Neurocritical Care liaison Spring 2001 – Spring 2009 American Academy of Neurology Section on Emergency and Critical Care Executive Committee January 2002 – 2004 Society of Critical Care Medicine Neurosciences Section, Chair-Elect August 2002 – September 2014 Neurocritical Care Society Board of Directors, founding member January 2004 – Present Society of Critical Care Medicine Neurosciences Section, Chair January 2002 – 2004 AANS/Brain Trauma Foundation Guidelines for the Management of Severe Traumatic Brain Injury Committee November 2012 – Present Neurocritical Care Society Brain Death Subcommittee of NCS Ethics Committee January 2013 – Present Neurocritical Care Society External Ventricular Drains Guidelines Committee and co-author January 2015 – Present Neurocritical Care Society Emergency Neurological Life Support Subcommittee on Certification, Co-Chair
  • 6.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 6 Community (e.g., presentationsfor lay audiences, educational outreach, media presentations/interviews) News service interviews: Traumatic brain injury, stroke, and hemicraniectomy, hypothermia: MSNBC et al. Michigan Stroke Initiative, Enhancing Access to Acute Stroke Care in Michigan Communities, 1999-2011 Great Lakes Transplantation Association, medicaladvisory board, 1999- 2011 Wayne County Traffic Safety Commission, 2000-2011 Community Stroke education, Detroit, MI Community Education and Feedback for Waiver of Informed Consent for Hemicraniectomy clinical trial, Detroit, MI Brain Injury Association of Michigan Brain Injury Association of Colorado, May 2014 Online Live Chat – Stroke Prevention – Centura Health, May 2013 Centura Health Neurosciences System of Care, Affiliate, Critical Accessand Community Outreach, May 2013-January 2015 (* = multiple) – includes presentations, clinical and didacticeducation, case reviews, etc Cheyenne Regional Medical Center, Cheyenne, WY Denver Health Medical Center, Denver, CO Aspen Valley Hospital, Aspen, CO St. Vincent’s Hospital, Leadville, CO* Longmont United Hospital, Longmont, CO* Platte Valley Medical Center, Brighton, CO* Good Samaritan Medical Center, Lafayette, CO Heart of The Rockies Regional Medical Center, Salida, CO* San Luis Valley Regional Medical Center, Alamosa, CO* Rio Grande Hospital, Del Norte, CO* Conejos County Hospital, La Jara, CO Pagosa Springs Medical Center, Pagosa Springs, CO* San Juan Regional Medical Center, Farmington, NM Southwest Memorial Hospital, Cortez, CO Lincoln Community Hospital, Hugo, CO Miners’ Colfax Medical Center, Raton, NM Kit Carson County Memorial Hospital, Burlington, CO Goodland Regional Medical Center, Goodland, KS Consulting Remifentanil Advisory Board, Glaxo-Wellcome, February 1998
  • 7.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 7 Tirilazad Mesylate inSAH advisory panel, Pharmacia & Upjohn, April 1999 Innercool Therapies, Stroke Initiative, April 2000 Medivance Hypothermia Panel/Arctic Circle, Feb. 2002 – 2011 Integra Neurosciences, 2002 – Present Ortho-McNeil, 2003 – 2008 ESP Pharma, 2003 – 2005 PDL Biopharma, 2005-2008 UCB Pharma, 2015 – Present Bard Medical, 2015 – Present Multiple investment banking organizations Scholarly Service Grant Review Committees National June 1999 - 2005 NIH/NINDS - Member Cell Death and Injury in Neurodegeneration Study Section (formerly Brain Disorders and Clinical Neurosciences –3) NIH/NINDS: Clinical Trials Study Group – Ad hoc Regional/Local Rehabilitation Institute of Michigan internal grant reviews – last 2011 Service for Peer-Reviewed Journals Editorial Board Membership – Neurocritical Care Review of Manuscripts – ad hoc reviews for Neurosurgery, Journal of the Neurological Sciences, American Journal of Kidney Diseases, Respiratory Care, Neurology, Stroke, Archives of Neurology, Cerebrovascular Diseases, New England Journal of Medicine, Journal of Stroke and Cerebrovascular Diseases, Annals of Neurology, Journal of Neuroimaging, Critical Care, and Critical Care Medicine Moderator for numerous scientific sessions, e.g., Rocky Mountain Neurocritical Care Conference, Denver, 2013 (Course Director); Neurocritical Care Society; Society of Critical Care Medicine (Course Director, Neurocritical Care); American Academy of Neurology (Course director, Neurotrauma, 2002-
  • 8.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 8 2003); International NeurocriticalCareSymposia – Panama; IInd National Workshop – Critical Care Neurology, Hyderabad, India (Course Director, Critical Care Neurology, 2003) OTHER SERVICE DATES TEACHING Centura Health Neurosciences System of Care, Centura Health Hospital Affiliates, Colorado Critical Access Hospital Outreach Undergraduate students Bedside rounding Nursing and Respiratory Therapy Medical students Bedside rounding Rocky Vista University College of Osteopathic Medicine Residents/Fellows Bedside rounding and didactic (see didactic below) St. Anthony Hospital Surgical residents University of ColoradoPulmonary & Critical Care Medicine fellows Physicians/Nurses/Pharmacists (CME/CEU/CE) Bedside/clinical rounds; didactics; case reviewsfor Neurology, Stroke/ICH/SAH, Neurosurgery, Trauma, Neuroradiology, Skull-Base Surgery/Otolaryngology/Head & Neck Surgery, and Emergency Medicine; also see Invited Lectures/Presentations Wayne State University Teaching at Wayne State University Under the categories below, list course number/title or type of teaching activity and your role. Indicate year(s) when taught. Undergraduate students Shadowing elective in Neurology/Neuro-Emergencies/Neurocritical Care/Neurotrauma for high school and Wayne State University college students Graduate students School of Pharmacy Students – regular rotation through NeuroICU Shadowing elective for Wayne State University Law School students Neuropsychology resident and fellow didactics – traumatic brain injury Certified Registered Nurse Anesthetist students Lectures - airway management and ventilation of the brain-injured Clinical Preceptorship – neuroemergencies, neurotrauma, and neurocritical care Advanced Cinical Nurse Practitioner students 2013-2015 1996-2012
  • 9.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 9 Clinical Preceptorship -neuroemergencies, neurotrauma, and neurocritical care Medical students Year Two – lectures and small group didactic sessions Neuropathophysiology course Objective Structured Clinical Exam Neurology Clinical Vignettes Year Three – attending physician for Neurocritical Care/Neurology clinical rotation – included didactic core lectures Year Four – elective clinical attending and preceptorships in Neurocritical Care, Neurology, Stroke/Vascular Neurology, Neurological Surgery, Critical Care Medicine, Trauma Surgery, and Emergency Medicine – included didactic lectures Residents/Fellows Neurology Residents – rounding attending physician (NeuroICU and ward services), mentoring, didactic lectures Neurology Resident Teaching Conference Neurology Journal Club Neurology Professor’sRounds Stroke Conference Neurological Surgery Residents – rounding attending physician, (NeuroICU and ward services), mentoring, didactic lectures Neurosurgery Resident Core Lectures Neurosurgery Journal Club Neurotrauma Conference Emergency Medicine Residents – rounding attending physician (1st -year NeuroICU rotation and Senior Resident electives), mentoring, didactic lectures Pharmacy Practice Residents -- rounding attending physician (NeuroICU rotation), research mentoring, didactic lectures General Surgery Residents – rounding consulting physician, mentoring Trauma Conference Internal Medicine Residents’ board review - Neurology Physical Medicine & Rehabilitation Residents – NeuroICU elective rounding attending physician, mentoring, didactic lectures Physical Medicine & Rehabilitation Lecture Series Neurotrauma Fellows – Program Director, rounding attending physician, research mentoring, didactic lectures Neurocritical Care Fellows -- Program Director, rounding attending physician, research mentoring, didactic lectures
  • 10.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 10 Pulmonary & CriticalCare Medicine Fellows – rounding attending physician (scheduled Neurocritical Care rotation and electives), mentoring, didactic lectures Core Lectures Fundamentals in Critical Care Support Course – Neurologic Assessment and Support Emergency Medicine Critical Care Fellows -- rounding attending physician, mentoring, didactic lectures Trauma Surgery Fellows -- rounding attending physician(scheduled Neurotrauma/Neurocritical Care rotation and elective), mentoring, didactic lectures Burn Surgery Fellows – rounding attending physician (elective Neurocritical Care rotation), mentoring, didactic lectures Physicians/Nurses/Pharmacists (CME/CEU/CE) Didactics; case reviews for Neurology, Stroke/ICH/SAH, Neurosurgery, Trauma, Neuroradiology, and Emergency Medicine; also see Invited Lectures/Presentations Nutritionist/dietician didactics Speech and Language Therapy didactics Faculty (CME) University of Washington Graduate Professional students Law B520 (Trial Advocacy) Medical students Human Biology 550 (Basic Neurology) Medicine 686 (Neurology Clerkship) Human Biology 541 (The Respiratory System) Residents/Fellows Neurology Resident Teaching Conferences Neurology Journal Club Neurological Surgery Resident Teaching Conference Respiratory/Critical Care Conference VA Chief of Medicine Rounds VA Medicine Noon Conferences University of Washington Medicine Noon Conferences Swedish Hospital Medicine Noon Conferences Swedish Hospital Medicine Morning Report Physicians/Nurses/Pharmacists (CME/CEU/CE) Neurology, Neurological Surgery, Pulmonary & Critical Care Medicine Grand Rounds and conferences and didactics - also see Invited Lectures/Presentations Mentorship 1993-1996 1995 1993-1996 1993-1996 1995 1993-1996 1993-1996 1995
  • 11.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 11 Multiple medical, pharmacy,nurse anesthetist, acute care nurse practitioner, and dietician students and residents Faith Abbott, DO, neurotrauma fellow Prasad Policherla, MD, neurotrauma and neurocritical care fellow Rodney Leacock, MD, neurotrauma and neurocritical care fellow Jacqueline Kraus, MD, neurotrauma and neurocritical care fellow Gregory Norris, MD, neurotrauma and neurocritical care fellow Ahmed Abdulsalam, MD, neurocritical care fellow Benjamin Atkinson, MD, neurotrauma and neurocritical care fellow Theses/Dissertations mentoring assistance – Wayne State University Bill D. Underwood, MD, PhD, clinical and editorial, heat shock protein and other gene expression after penetrating traumatic braininjury Julie G. Pilitsis, MD, PhD, clinical and editorial, central nervous system free fatty acid metabolism and disposition after acute brain injury John J. Steele III, MD, PhD, clinical and editorial, electrophysiological alterationsand topography after acute brain injury Course and curriculum development  Refining Skills in Nutrition Support (Educational Planning Committee) 1999  Critical Care Neurology (IInd National Workshop – Critical Care Neurology, Hyderabad, India) 2003  Neurotrauma (American Academy of Neurology) 2002 & 2003  Neurocritical Care (Society of Critical Care Medicine) 2005-2009  Neurocritical Care in Catastrophic Conditions (Neurocritical Care Society) 2011  Rocky Mountain Neurocritical Care Conference (Centura Health) 2013 1995-1996 1993-1995 1993-1995 1993-1995 1993-1994 1993-1994 1993-1996 1996-2011 GRANTS, CONTRACTS, AND OTHER FUNDING Active and Pending Grants and Contracts None Previously funded NIH Grant as PI NIH/NINDS 1 RO1 NS38905-01, Early hemicraniectomy to manage traumatic brain injury. 7/16/99 – 6/30/03, $260,606 Previously submitted, not funded Grants and Contracts as PI NIH/NINDS 1 R21 NS048744-01, IntraCranial PressurePrevention and Control Investigation. (Coplin) 1999-2003 CLINICAL TRIALS ACTIVITIES Within last two years: • A Non-Transfer Protocol for Patientswith Stable, Mild, Isolated Traumatic Brain Injury at Level III and IV Trauma Centers, co-PI • Neurotelemetry: Remote cEEG Monitoring and Reading for Neurocritical Care Patient Management, co-PI and abstract presenter • Boehringer-Ingelheim 1160.189 (ESUS study), local PI – while at Centura Health • POINT, co-investigator – while at Centura Health • Association Between Pharmacological Thromboprophylaxis And Hemorrhage Progression In
  • 12.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 12 Patients With HemorrhagicStroke, co-investigator, abstract presenter, and lead author for manuscript in progress • Pharmacological Thromboprophylaxis Reducesthe Odds of Venous Thromboembolism In Patients With Hemorrhagic Stroke, co-investigator, abstract presenter, and lead author for manuscript in progress PUBLICATIONS • Recent and representative publications in journals(selected from > 69). Does not include presentations, abstracts, book chapters, or articles ‘in preparation’ or ‘submitted.’ Chesnut, R, et al. A Consensus-based Guide to the Interpretation of the BEST TRIP ICP Trial. J Neurotrauma. 2015;in press Wright DW, Yeatts SD, Silbergleit R, Palesch YY, Hertzberg VS, Frankel M, et al. Very early administration of progesterone for acute traumatic brain injury. N Engl J Med. 2014;371(26):2457- 66. Frank JI, Schumm LP, Wroblewski K, Chyatte D, Rosengart AJ, Kordeck C, et al. Hemicraniectomy and durotomy upon deterioration from infarction-related swelling trial: randomized pilot clinical trial. Stroke. 2014;45(3):781-7. Levy AS, Salottolo K, Coplin WM, Smith R, Santos P, Bar-Or D. Pharmocologic thromboprophylaxis reduces the odds of venous thromboembolism in patients with hemorrhagic stroke. Stroke. 2014 – presented at 2014 International Stroke Conference, San Diego Levy AS, Salottolo K, Coplin WM, Orlando A, Smith R, Santos P, Bar-Or D. Association between pharmacologic thromboprophylaxis and hemorrhage progression in patients with hemorrhagic stroke. Stroke. 2014 – presented at 2014 International Stroke Conference, San Diego Coplin WM. Traumatic spinal cord injury. In: NCS Practice Update Textbook, Neurocritical Care Society, 2014. Liu-DeRyke X, Levy PD, Parker D Jr, Coplin W, Rhoney DH. A prospective evaluation of labetalol versus nicardipine for blood pressure management in patients with acute stroke. Neurocrit Care. 2013;19:41-7. Bhattacharya P, Kansara A, Chaturvedi S, Coplin W. What drives the increasing utilisation of hemicraniectomy in acute ischaemic stroke? J Neurol Neurosurg Psychiatry. 2013; 84(7):727-31. Nagaraja N, Bhattacharya P, Norris G, Coplin W, Narayanan S, Xavier A, et al. Arrival by ambulance is associated with acute stroke intervention in young adults. J Neurol Sci. 2012;316(1- 2):168-9. Coplin WM. Critical care management of acute ischemic stroke. Neurology. Continuum (Minneap Minn). 2012;18(3):547-59. Naff N, Williams MA, Keyl PM, Tuhrim S, Bullock MR, Mayer SA, et al. Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial. Stroke. 2011;42(11):3009-16. Kullar R, Chin JN, Edwards DJ, Parker D, Coplin WM, Rybak MJ. Pharmacokinetics of single-dose
  • 13.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 13 daptomycin in patientswith suspected or confirmed neurological infections. Antimicrob Agents Chemother. 2011;55(7):3505-9. Rhoney DH, Coplin WM, Lin Y, Frankel M, Lyden PD, Levine SR. Time of day, outcome, and response to thrombolytic therapy: the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trial experience. J Stroke Cerebrovasc Dis. 2010;19(1):40-8. Browning L, Parker D, Jr., Liu-DeRyke X, Shah A, Coplin WM, Rhoney DH. Possible removal of topiramate by continuous renal replacement therapy. J Neurol Sci. 2010;288(1-2):186-9. Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, et al. Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke. 2008;39(6):1759-65. Ramappa P, Thatai D, Coplin W, Gellman S, Carhuapoma JR, Quah R, et al. Cardiac troponin-I: a predictor of prognosis in subarachnoid hemorrhage. Neurocrit Care. 2008;8(3):398-403. Liu-Deryke X, Janisse J, Coplin WM, Parker D, Jr., Norris G, Rhoney DH. A comparison of nicardipine and labetalol for acute hypertension management following stroke. Neurocrit Care. 2008;9(2):167-76. Chang CW, Torbey MT, Diringer MN, Coplin W, Mayer SA, Hemphill EC, et al. Neurointensivists: part of the problem or part of the solution? Crit Care Med. 2008;36(10):2963-4; author reply 5. Benson RR, Meda SA, Vasudevan S, Kou Z, Govindarajan KA, Hanks RA, et al. Global white matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury. J Neurotrauma. 2007;24(3):446-59. Murugappan A, Coplin WM, Al-Sadat AN, McAllen KJ, Schwamm LH, Wechsler LR, et al. Thrombolytic therapy of acute ischemic stroke during pregnancy. Neurology. 2006;66(5):768-70. Mayer SA, Coplin WM, Chang C, Suarez J, Gress D, Diringer MN, et al. Core curriculum and competencies for advanced training in neurological intensive care: United Council for Neurologic Subspecialties guidelines. Neurocrit Care. 2006;5(2):159-65. Mayer SA, Coplin WM, Chang C, Suarez J, Gress D, Diringer MN, et al. Program requirements for fellowship training in neurological intensive care: United Council for Neurologic Subspecialties guidelines. Neurocrit Care. 2006;5(2):166-71. Esper DH, Coplin WM, Carhuapoma JR. Energy expenditure in patients with nontraumatic intracranial hemorrhage. JPEN J Parenter Enteral Nutr. 2006;30(2):71-5. Borsody M, Burke A, Coplin W, Miller-Lotan R, Levy A. Haptoglobin and the development of cerebral artery vasospasm after subarachnoid hemorrhage. Neurology. 2006;66(5):634-40. Albers GW, Thijs VN, Wechsler L, Kemp S, Schlaug G, Skalabrin E, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol. 2006;60(5):508-17.
  • 14.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 14 Barrett RJ, HussainR, Coplin WM, Berry S, Keyl PM, Hanley DF, et al. Frameless stereotactic aspiration and thrombolysis of spontaneous intracerebral hemorrhage. Neurocrit Care. 2005;3(3):237-45. Larive LL, Rhoney DH, Parker D, Jr., Coplin WM, Carhuapoma JR. Introducing hypertonic saline for cerebral edema: an academic center experience. Neurocrit Care. 2004;1(4):435-40. Rhoney DH, Tam VH, Parker D, Jr., McKinnon PS, Coplin WM. Disposition of cefepime in the central nervous system of patients with external ventricular drains. Pharmacotherapy. 2003;23(3):310-4. Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Free fatty acids in cerebrospinal fluids from patients with traumatic brain injury. Neurosci Lett. 2003;349(2):136-8. Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Measurement of free fatty acids in cerebrospinal fluid from patients with hemorrhagic and ischemic stroke. Brain Res. 2003;985(2):198-201. Carhuapoma JR, Gupta K, Coplin WM, Muddassir SM, Meratee MM. Treatment of refractory fever in the neurosciences critical care unit using a novel, water-circulating cooling device. A single-center pilot experience. J Neurosurg Anesthesiol. 2003;15(4):313-8. Rhoney DH, Parker D, Jr., Formea CM, Yap C, Coplin WM. Tolerability of bolus versus continuous gastric feeding in brain-injured patients. Neurological Res. 2002;24(6):613-20. Pilitsis JG, Coplin WM, O'Regan MH, Wellwood JM, Diaz FG, Fairfax MR, et al. Free fatty acids in human cerebrospinal fluid following subarachnoid hemorrhage and their potential role in vasospasm: a preliminary observation. J Neurosurg. 2002;97(2):272-9. Narayan RK, Michel ME, Ansell B, Baethmann A, Biegon A, Bracken MB, et al. Clinical trials in head injury. J Neurotrauma. 2002;19(5):503-57. Kraus JJ, Metzler MD, Coplin WM. Critical care issues in stroke and subarachnoid hemorrhage. Neurol Res. 2002;24 Suppl 1:S47-57. Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med. 2002;30(1):119-41. Coplin WM, Rhoney DH, Rebuck JA, Clements EA, Cochran MS, O'Neil BJ. Randomized evaluation of adverse events and length-of-stay with routine emergency department use of phenytoin or fosphenytoin. Neurol Res. 2002;24(8):842-8. Tirschwell DL, Coplin WM, Becker KJ, Vogelzang P, Eskridge J, Haynor D, et al. Intra-arterial urokinase for acute ischemic stroke: factors associated with complications. Neurology. 2001;57(6):1100-3. Pilitsis JG, Diaz FG, Wellwood JM, O’Regan MH, Fairfax MR, Phillis JW, et al. Quantification of free fatty acids in human cerebrospinal fluid. Neurochem Res. 2001;26(12):1265-70. Joshi N, Chaturvedi S, Coplin WM. Poor prognosis of acute stroke patients denied thrombolysis
  • 15.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 15 due to earlyCT findings. J Neuroimaging. 2001;11(1):40-3. Coplin WM, Cullen NK, Policherla PN, Vinas FC, Wilseck JM, Zafonte RD, et al. Safety and feasibility of craniectomy with duraplasty as the initial surgical intervention for severe traumatic brain injury. J Trauma. 2001;50(6):1050-9. Coplin WM, Cochran MS, Levine SR, Crawford SW. Stroke after bone marrow transplantation: frequency, aetiology and outcome. Brain. 2001;124(Pt 5):1043-51. Coplin WM, Broderick J, Tomsick TT. Intraarterial recombinant tissue plasminogen activator for ischemic stroke: an accelerated dosing regimen. Neurosurgery. 2001;49(1):228-9. Coplin WM. Intracranial pressure and surgical decompression for traumatic brain injury: biological rationale and protocol for a randomized clinical trial. Neurol Res. 2001;23(2-3):277-90. Vinas FC, Kazmierczak C, Coplin WM. Active intracerebral hemorrhage from the lateral posterior choroidal artery. Arch Neurol. 2000;57(6):889-90. Tipps LB, Coplin WM, Murry KR, Rhoney DH. Safety and feasibility of continuous infusion of remifentanil in the neurosurgical intensive care unit. Neurosurgery. 2000;46(3):596-601; discussion - 2. Rhoney DH, Tipps LB, Murry KR, Basham MC, Michael DB, Coplin WM. Anticonvulsant prophylaxis and timing of seizures after aneurysmal subarachnoid hemorrhage. Neurology. 2000;55(2):258-65. Rebuck JA, Murry KR, Rhoney DH, Michael DB, Coplin WM. Infection related to intracranial pressure monitors in adults: analysis of risk factors and antibiotic prophylaxis. J Neurol Neurosurg Psychiatry. 2000;69(3):381-4. Devlin JW, Coplin WM, Murry KR, Rengachary SS, Wilson RF. Nimodipine-induced acute hypoxemia: case report. Neurosurgery. 2000;47(5):1243-6; discussion 6-7. Coplin WM, Pierson DJ, Cooley KD, Newell DW, Rubenfeld GD. Implications of extubation delay in brain-injured patients meeting standard weaning criteria. Am J Respir Crit Care Med. 2000;161(5):1530-6. PRESENTATIONS International/national, local/regional, and invited Seminars and Grand Rounds since May 2013 1. Online Live Chat – Stroke Prevention – Centura Health – 5/23/13 2. Stroke in the Emergency Department: What to do… - St. Catherine Hospital (med staff) – 5/29-13 3. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – University of Virginia Neurology Grand Rounds – 5/31/13 4. Optimal Glucose Control in Hemorrhagic Stroke – St. Anthony Hospital (MD/RN) – 6/13/13 5. TBI Case Studies – St. Anthony Neuro/Trauma Nursing Staff – monthly x 2, first 6/14/13 6. Brain Injury Management – Grand Rounds Santo Tomas Hospital, Panama – 6/19/13
  • 16.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 16 7. Delayed BrainInjury - 3rd International Neurocritical Care Symposium, Panama – 6/20/13 8. Updates in Neuromonitoring of TBI Patients - 3rd International Neurocritical Care Symposium, Panama – 6/20/13 9. Brain Tissue Oxygen Based Therapy and Outcome after Severe Traumatic Brain Injury - 3rd International Neurocritical Care Symposium, Panama – 6/21/13 10. Update in the Management of Traumatic Spinal Cord Injury - 3rd International Neurocritical Care Symposium, Panama – 6/21/13 11. Traumatic Spinal Cord Injury – St. Anthony Trauma Multidisciplinary QI – 7/1/13 12. Early Goal Directed Therapy for Traumatic Brain Injury – Cheyenne Regional Medical Center (WY) – 7/9/13 13. Hospital Neurological Assessments – Penrose Hospital (Centura Stroke Coordinators’ monthly meeting) – 7/12/13 14. Traumatic Spinal Cord Injury – Panorama Orthopedics (physician/PA staff) – 7/15/13 15. Controversies in Spine Injury – Parker Adventist Hospital (Spine Committee) – 7/30/13 16. Clearing the Spine in the ED: Exam, Imaging, Gear Removal, and Transition to Further Care: The Neuro Doc's Perspective – 1st Annual Rocky Mountain Sports Medicine Symposium, Durango – 8/2/13 17. Hypoxia Unplugged: Altitude and Carbon Monoxide– 1st Annual Rocky Mountain Sports Medicine Symposium, Durango – 8/3/13 18. Neurological Assessment – St. Anthony North (nursing) – 8/7/13 19. You Won’t Get Far If You Keep On Sticking Your Hand In The Medicine Jar: Steroids Work, Don’t They? – Littleton Adventist Hospital (trauma) – 8/15/13 20. Transfusion “Requirements” in Traumatic Brain Injury – Littleton Adventist Hospital (trauma) – 8/15/13 21. Toxic Encephalopathies: Ethanol Withdrawal – Critical Care Karma, Porter Adventist Hospital – 8/21/13 22. Blood Pressure Management for Different Types of Stroke - St. Anthony Hospital – 8/26/13 23. Severe Traumatic Brain Injury: Initial Assessment and Resuscitation – St. Anthony Hospital – 8/29/13 24. Use of Clinical Examination Scales in Patients with Neurological Injury: Why All the Confusion? – St. Anthony Hospital (Neurocritical Care board review series) – 9/9/13 25. Monitoreo Multimodal en Neurointensivo - Asociación Colombiana de Medicina Interna – Pasto – 9/13/13 26. Presión Tisular de Oxígeno Cerebral - Asociación Colombiana de Medicina Interna – Pasto – 9/13/13 27. Minimizing Perioperative Spine Surgery Infections: Why All The Confusion? – Parker Adventist Hospital (Spine Committee) – 9/17/13 28. Traumatic Spinal Cord Injury – Neurocritical Care Society – Philadelphia – 10/2/13 29. General Approach to Ventilating the Comatose Trauma Patient – St. Anthony Hospital (trauma) – 10/7/13 30. Fluids, Electrolytes, Resuscitation Do’s and Don’ts – St. Anthony Hospital (Neurocritical Care board review series) – 10/10/13 31. Hypercalcemia – Heart of the Rockies Regional Medical Center, Salida – 10/10/13 32. Coagulopathies – Littleton Adventist Hospital (trauma) – 10/17/13 33. Acute Management of Neurological Emergencies – St. Mary-Corwin (nursing) – 10/19/13 34. Neuropharmacology – Rocky Mountain Neurocritical Care Conference – 10/29/13 35. Neuroendocrinology – Rocky Mountain Neurocritical Care Conference – 10/30/13 36. Spinal Cord Injury – Rocky Mountain Neurocritical Care Conference – 10/30/13 37. Natural, Supernatural, and Man-Made Catastrophes – Rocky Mountain Neurocritical Care Conference – 10/30/13
  • 17.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 17 38. Zombie Neurobiology:Are We Ready For The Looming Apocalypse? – St. Mary’s Medical Center’s 4th Annual Neuroscience Symposium – Advancements in Neuroscience, Palm Beach Gardens, FL – 11/2/13 39. Traumatic Intracranial Hemorrhage – Mercy Regional Medical Center Trauma Conference – 11/9/13 40. Traumatic Intracranial Hemorrhage – Mercy Regional Medical Center – 11/11/13 41. Toxic Encephalopathies: Ethanol Withdrawal – Mercy Regional Medical Center – 11/11/13 42. Mild TBI Transfer Algorithm – Mercy Regional Medical Center – 11/13/13 43. Zombie Neurobiology: Are We Ready For The Looming Apocalypse? – Critical Care Karma - 11/18/13 44. Severe TBI – St. Anthony Hospital (Neurocritical Care board review series) – 11/26/13 45. Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The Confusion? – St. Vincent Hospital, Leadville – 12/2/13 46. Multimodality Monitoring in Neurocritical Care – St. Anthony Hospital (Neurocritical Care board review series) – 12/5/13 47. Spinal Cord Injury – St. Anthony Hospital (nursing) – 12/6/13 48. There Will Be Blood – Aspen Valley Hospital (trauma) – 12/10/13 49. Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The Confusion? – Mercy Regional Medical Center – 12/11/13 50. “Neuroradiology”. Lecture for RNs. St. Anthony Hospital - 2/20/14 51. “HACA: 33 vs 36C”. CCPSA Journal Club. St. Anthony Hospital - 2/24/14 52. “Traumatic Brain Injury”. Wilz Neuroscience and Trauma Symposium. Pueblo Convention Center - 3/1/14 53. “Appropriate TBI Admissions and TBI Management, Including Rehab and Follow Up”. San Luis Valley Regional Medical Center - 3/17/14 54. “Fluid and Electrolyte Management In Critically-Ill Patients After Neurological Catastrophes”. Neurotrauma Critical Care Review and Update for Practicing Neurosurgeon. 82nd American Association of Neurological Surgeons Annual Scientific Meeting, San Francisco - 4/5/14 55. “Traumatic Brain Injury”. Miners’ Colfax Medical Center. Raton, NM - 4/10/14 56. “Telestroke” St. Thomas More Emergency Department. Canon City, CO - 4/16/14 57. “Alcohol Withdrawal Syndrome: A New Approach To Prevention and Intervention of Severe Alcohol Withdrawal Symptoms”. Mercy Regional Medical Center. Durango, CO - 4/17/14 58. “Alcohol Withdrawal Syndrome: Interdepartmental/Interdisciplinary Approach Based on the Evidence Based Medicine Review”. Mercy Regional Medical Center. Durango, CO - 4/17/14 59. “Alcohol Withdrawal Syndrome: Protocol/Standardization of Treatment in Inpatients, Pre- ICU, ICU, and ED Patients”. Mercy Regional Medical Center. Durango, CO - 4/17/14 60. “Traumatic Brain Injury”. Platte Valley Medical Center - 4/24/14 61. “Therapeutic Temperature Management after Neurological Catastrophe: Why All the Confusion?”. Trauma Multidisciplinary Meeting. St. Anthony Hospital - 5/5/14 62. “Hospital Neurological Stroke Assessments”. Mega Nursing Grand Rounds. Porter Adventist Hospital - 5/6/14 63. “Disability”. Rural Trauma Team Development Course. San Luis Valley Regional Medical Center - 5/8/14 64. “Zombie Neurobiology: Are We Ready For The Looming Apocalypse?” South State EMS. Penrose Hospital. Colorado Springs, CO - 5/13/14 65. “Workup, Management, and Disposition of Mild Traumatic Brain Injury: Why All The Confusion?” Pagosa Springs Medical Center - 5/15/14 66. “Mild Brain Injury – When to Refer; When and Where to Manage”. Brain Injury Alliance of
  • 18.
    ___________________________________________________________________________________________________ COPLIN_CV_05.06.2015 18 Colorado Summit CountyConference. Beaver Run, CO - 5/16/14 67. “VTE Prophylaxis Timing after Brain and/or Spinal Cord Injury”. Penrose-St. Francis Trauma Education. Colorado Springs, CO – 9/5/14 68. “Traumatic Spinal Cord Injury”. Neurocritical Care Society. Seattle, WA – 9/10/14 69. “Guidelines are great for neurocritical care in general, but not for real experts like me.” Neurocritical Care Society. Seattle, WA – 9/14/14 70. “Concussion”. Copper Mountain Emergency Medicine. Edwards, CO – 10/23/14 71. “Head Injury and Hollywood: A Case Study of the Three Stooges”. Mercy Regional Medical Center Trauma Conference. Durango, CO – 10/25/14 72. “Urgent Warfarin Reversal”. Association of California Nurses. Santa Ana, CA – 10/28/14 73. “Association Between Pharmacological Thromboprophylaxis and Hemorrhage Progression in Patients with Hemorrhagic Stroke”. St. Mary’s Medical Center’s 5th Annual Neuroscience Symposium – A Lustrum of Progress. Palm Beach Gardens, FL – 11/1/14 74. “Association Between Pharmacologic Thromboprophylaxis and Hemorrhage Progression in Patients With Hemorrhagic Stroke”. Best of AHA Specialty Conferences at Scientific Sessions. Chicago, IL – 11/17/14 75. “Concussion and Clearing the Spine in the ED: Exam, Imaging, Gear Removal, and Transition to Further Care”. Rio Grande Hospital Quarterly Trauma Review and CME. Del Norte, CO – 11/21/14 76. “Current Trends In Neurotrauma”. Wilz Trauma Symposium. Pueblo, CO – 3/7/15 77. “Zombie Neurobiology: Are We Ready For The Looming Apocalypse?”. 12th Annual Critical Care Symposium. Manchester, UK – 4/23/15 78. “Pharmacological Thromboprophylaxis, Venous Thromboembolism & Hemorrhage Progression In Patients With Hemorrhagic Stroke: Why All The Confusion? 12th Annual Critical Care Symposium. Manchester, UK – 4/24/15 79. “Neurocritical Care Update” 12th Annual Critical Care Symposium. Manchester, UK – 4/24/15 80. “Extubation Readiness Independent Of Level Of Consciousness”. 12th Annual Critical Care Symposium. Manchester, UK – 4/24/15 81. “Coagulopathy and VTE: Timing of Use of Chemical Prophylaxis & Management of VTE Events in the Perioperative Period”. Neurotrauma Critical Care Review and Update. 83rd American Association of Neurological Surgeons Annual Scientific Meeting. Washington, DC – 5/2/15